-
Notifications
You must be signed in to change notification settings - Fork 17
Description
Describe the bug
A clear and concise description of what the bug is.
I was using Manta (Galaxy Version 1.6+galaxy9 and also Galaxy Version 1.6+galaxy8) and selecting "Additional parameters --> Set options for WES input: turn off depth filters" does not seem to be working properly.
Upon checking the command line in the diploidSV.vcf.gz header, I got this:
##cmdline=/usr/local/bin/configManta.py --referenceFasta=localref.fa --config=./configManta.py.ini --bam=normal.bam --runDir=./MantaWorkflow --scanSizeMb=12 --callMemMb=8000
I was expecting the argument --exome to appear in the command line, but it did not. Moreover, I found the FILTER field in my vcf file still reports "MaxDepth" flag, which should not has appeared if depth filters were turned off for the exome mode. For example:
#CHROM | POS | ID | REF | ALT | QUAL | FILTERchr1 | 6440498 | MantaBND:32:49:49:0:0:0:0 | G | [chr1:6440589[G | 0 | MaxDepth;MinQUAL;SampleFT