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title: "Culhane Computational Oncology & Cancer Genomics Lab"
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title: "Culhane Computational Oncology & Cancer Genomics Lab"
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# Computational Oncology & Cancer Genomics

We develop computational tools and algorithms to understand cancer biology and improve treatment outcomes.
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### Our Research

We specialize in developing algorithms for multi-modal analysis of cancer omics data, creating tools to discover insights into tumor evolution and treatment efficacy.

[Explore Projects](projects.html){.btn .btn-primary}
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### Connected Data

We lead initiatives in federated cancer data infrastructure, working with global consortiums to build frameworks that improve cancer research and care.

[Learn More](Projects/eHealthHub.html){.btn .btn-primary}
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### Open Science

We embrace open science principles, contributing to Bioconductor and sharing tools with the research community to accelerate cancer research globally.

[See Our Software](software.html){.btn .btn-primary}
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## Recent Publications

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#### Correspondence analysis for dimension reduction, batch integration, and visualization of single-cell RNA-seq data

**Hsu LL, Culhane AC** (2023) Scientific Reports

[Read Paper](https://doi.org/10.1038/s41598-022-26434-1){.btn .btn-sm .btn-outline-secondary}
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#### Anti-CAIX BBζ CAR4/8 T cells exhibit superior efficacy in a ccRCC mouse model

**Wang Y, Buck A, Grimaud M, Culhane AC,** et al. (2022) Molecular Therapy Oncolytics

[Read Paper](https://doi.org/10.1016/j.omto.2021.12.019){.btn .btn-sm .btn-outline-secondary}
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[View All Publications](publications.html){.btn .btn-primary .mt-3}
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## Latest News

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### New Grant Award

Our lab has received funding for all-island eHealth research in cancer.

[Read More](News/22-04-04_LimerickPost.html){.btn .btn-sm .btn-outline-secondary}
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### RTE Brainstorm Article

Prof Aedin Culhane and Prof Mark Lawler spoke with RTE Brainstorm about the pressing need for harmonization of clinical cancer health data.

[Read More](News/22_05_19_BrainStorm.html){.btn .btn-sm .btn-outline-secondary}
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[View All News](news.html){.btn .btn-primary}
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