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# **PLAPT: Protein-Ligand Binding Affinity Prediction Using Pretrained Transformer Models**
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# **PLAPT: Protein-Ligand Binding Affinity Prediction Using Pretrained Transformers**
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This is the official code repository for PLAPT, a state-of-the-art 1D sequence-only protein-ligand binding affinity predictor, first introduced [here](https://community.wolfram.com/groups/-/m/t/3094670)
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#### Importing Encoders and Running the Notebook
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For users to import the encoders and run the Wolfram notebook (`WL Notebooks/FinalEssay.nb`), we provide the `encoders_to_onnx.ipynb` notebook. This ensures that users can replicate our encoding process and utilize the full capabilities of PLAPT.
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### Results
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PLAPT achieved impressive results, demonstrating both high accuracy and state-of-the-art generalization in protein-ligand binding affinity prediction. Detailed analysis can be found in our paper. Key metrics include:
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