DESCRIPTION

Package: avengeme
Title: Analysis of polygenic scoring methods
Version: 1.0
Authors@R: c(person("Frank", "Dudbridge", email = "frank.dudbridge@leicester.ac.uk", role = c("aut", "cre")),
             person("Christopher B.", "Cole", email = "chris.c.1221@gmail.com", role = c("aut", "cre")),
             person("Luigi","Palla", email = "luigi.palla@lshtm.ac.uk", role = c("aut")))
Description: AVENGEME (Additive Variance Explained and Number of Genetic Effects Method of Estimation) is a package for the analysis of the polygenic scoring method. Polygenic scores access a large proportion of the heritability of a trait by aggregating genetic effects across thousands of markers into a single composite score. The markers may not be individually associated with the trait at standard statistical significance levels. However, the composite score may be associated, indicating a substantial polygenic component within the score.
Depends: R (>= 3.0.0)
License: GPL-3
Encoding: UTF-8
LazyData: true
RoxygenNote: 6.0.1
Author: Frank Dudbridge [aut, cre]
Maintainer: Frank Dudbridge <frank.dudbridge@leicester.ac.uk>
Imports: mvtnorm
Suggests: shiny