diff --git a/package.json b/package.json
index 975d66d962..c23930f7d0 100644
--- a/package.json
+++ b/package.json
@@ -45,7 +45,7 @@
     "@babel/plugin-transform-runtime": "^7.4.4",
     "@babel/polyfill": "^7.4.4",
     "@gmod/bam": "^1.0.15",
-    "@gmod/cram": "^1.5.1",
+    "@gmod/cram": "^1.5.3",
     "@gmod/gff": "^1.1.1",
     "@gmod/indexedfasta": "^1.0.11",
     "@gmod/tabix": "^1.1.5",
diff --git a/webpack.config.js b/webpack.config.js
index 14d8e0df80..5bf3bf4706 100644
--- a/webpack.config.js
+++ b/webpack.config.js
@@ -62,7 +62,7 @@ var webpackConf = {
         rules: [
             {
                 test: /\.js$/,
-                exclude: /node_modules\/(?!(quick-lru|@gmod\/cram|@gmod\/bam|@gmod\/indexedfasta|@gmod\/tabix|@gmod\/tribble-index|@gmod\/binary-parser|@gmod\/bgzf-filehandle))/,
+                exclude: /node_modules\/(?!quick-lru)/,
                 use: {
                     loader: 'babel-loader',
                     options: {
diff --git a/yarn.lock b/yarn.lock
index 649ccc0ba9..9f3f5df481 100644
--- a/yarn.lock
+++ b/yarn.lock
@@ -699,6 +699,14 @@
     core-js "^2.6.5"
     regenerator-runtime "^0.13.2"
 
+"@babel/runtime-corejs3@^7.4.5":
+  version "7.4.5"
+  resolved "https://registry.yarnpkg.com/@babel/runtime-corejs3/-/runtime-corejs3-7.4.5.tgz#7df89702351c5fdc34b5555544fcf11b4ea7051c"
+  integrity sha512-yxHpUObdpx4zbuLJOHIZkw43E4NbWGsGH+85kRUj+VEcdtjlqI0vDcAja9mwOHqD7/4vCZp69q6eztz/sFDibQ==
+  dependencies:
+    core-js-pure "^3.0.0"
+    regenerator-runtime "^0.13.2"
+
 "@babel/runtime@^7.3.4", "@babel/runtime@^7.4.4":
   version "7.4.4"
   resolved "https://registry.yarnpkg.com/@babel/runtime/-/runtime-7.4.4.tgz#dc2e34982eb236803aa27a07fea6857af1b9171d"
@@ -818,13 +826,6 @@
     long "^4.0.0"
     pako "^1.0.10"
 
-"@gmod/binary-parser@^1.3.2":
-  version "1.3.3"
-  resolved "https://registry.yarnpkg.com/@gmod/binary-parser/-/binary-parser-1.3.3.tgz#a29b69e19afcce8fff632cf0325c7c24d4544792"
-  integrity sha512-+NZOfXj9Ajd6Yr2GW7I4mH+2uEjoBQALznDRoPiMyYZek3s0r8mHB30L9SS0OjzdINx2hM+zXf1uRD/b8Nv8PA==
-  dependencies:
-    long "^4.0.0"
-
 "@gmod/binary-parser@^1.3.5":
   version "1.3.5"
   resolved "https://registry.yarnpkg.com/@gmod/binary-parser/-/binary-parser-1.3.5.tgz#6b460565ce8b2df2c03c05b5a617791dfd779c35"
@@ -832,13 +833,13 @@
   dependencies:
     long "^4.0.0"
 
-"@gmod/cram@^1.5.1":
-  version "1.5.2"
-  resolved "https://registry.yarnpkg.com/@gmod/cram/-/cram-1.5.2.tgz#e6748fbd210a41693c65f537e2d6a09a33e8c076"
-  integrity sha512-FGK3qwp0ByZgSnuJCn1AtUYsvn+/tR6sgychS2E+xF8IO5bbVnvgKL0HmUWwlW/XCGqwuhuyTk8ETzIB6/2vEg==
+"@gmod/cram@^1.5.3":
+  version "1.5.3"
+  resolved "https://registry.yarnpkg.com/@gmod/cram/-/cram-1.5.3.tgz#25a1395d49509b76eb90254fa0f5ba792cc48e56"
+  integrity sha512-LK8DlJn40isAclD9VfnQFvCXcaXuA37LClCER/cEOutLC0NyFYr7KaGQ+/RF2uZpu65VFf9jt2JleSNyaba+bQ==
   dependencies:
-    "@gmod/binary-parser" "^1.3.2"
-    babel-runtime "^6.26.0"
+    "@babel/runtime-corejs3" "^7.4.5"
+    "@gmod/binary-parser" "^1.3.5"
     buffer-crc32 "^0.2.13"
     cross-fetch "^3.0.0"
     es6-promisify "^6.0.1"
@@ -2718,7 +2719,7 @@ core-js-compat@^3.1.1:
     core-js-pure "3.1.2"
     semver "^6.0.0"
 
-core-js-pure@3.1.2:
+core-js-pure@3.1.2, core-js-pure@^3.0.0:
   version "3.1.2"
   resolved "https://registry.yarnpkg.com/core-js-pure/-/core-js-pure-3.1.2.tgz#62fc435f35b7374b9b782013cdcb2f97e9f6dffa"
   integrity sha512-5ckIdBF26B3ldK9PM177y2ZcATP2oweam9RskHSoqfZCrJ2As6wVg8zJ1zTriFsZf6clj/N1ThDFRGaomMsh9w==