diff --git a/.github/workflows/tpu.yaml b/.github/workflows/tpu.yaml
new file mode 100644
index 00000000000..311d65db710
--- /dev/null
+++ b/.github/workflows/tpu.yaml
@@ -0,0 +1,54 @@
+# Copyright 2024 Google LLC
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#      http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+name: tpu
+on:
+  push:
+    branches:
+    - main
+    paths:
+    - 'tpu/**'
+    - '.github/workflows/tpu.yaml'
+    - '.github/workflows/test.yaml'
+  pull_request:
+    types:
+    - opened
+    - reopened
+    - synchronize
+    - labeled
+    paths:
+    - 'tpu/**'
+    - '.github/workflows/tpu.yaml'
+    - '.github/workflows/test.yaml'
+  schedule:
+  - cron:  '0 0 * * 0'
+jobs:
+  test:
+    # Ref: https://github.com/google-github-actions/auth#usage
+    permissions:
+      contents: 'read'
+      id-token: 'write'
+    if: github.event.action != 'labeled' || github.event.label.name == 'actions:force-run'
+    uses: ./.github/workflows/test.yaml
+    with:
+      name: 'tpu'
+      path: 'tpu'
+  flakybot:
+    # Ref: https://github.com/google-github-actions/auth#usage
+    permissions:
+      contents: 'read'
+      id-token: 'write'
+    if: github.event_name == 'schedule' && always() # always() submits logs even if tests fail
+    uses: ./.github/workflows/flakybot.yaml
+    needs: [test]
\ No newline at end of file
diff --git a/.github/workflows/utils/workflows.json b/.github/workflows/utils/workflows.json
index ff954978f83..49884faf2d6 100644
--- a/.github/workflows/utils/workflows.json
+++ b/.github/workflows/utils/workflows.json
@@ -90,6 +90,7 @@
   "speech",
   "talent",
   "texttospeech",
+  "tpu",
   "translate",
   "video-intelligence",
   "vision/productSearch",
diff --git a/CODEOWNERS b/CODEOWNERS
index beba1e13c79..c1391fc278e 100644
--- a/CODEOWNERS
+++ b/CODEOWNERS
@@ -20,6 +20,7 @@ compute @GoogleCloudPlatform/dee-infra @GoogleCloudPlatform/nodejs-samples-revie
 iam @GoogleCloudPlatform/dee-infra @GoogleCloudPlatform/nodejs-samples-reviewers @GoogleCloudPlatform/cloud-samples-reviewers
 kms @GoogleCloudPlatform/dee-infra @GoogleCloudPlatform/nodejs-samples-reviewers @GoogleCloudPlatform/cloud-samples-reviewers
 orgpolicy @GoogleCloudPlatform/dee-infra @GoogleCloudPlatform/nodejs-samples-reviewers @GoogleCloudPlatform/cloud-samples-reviewers
+tpu @GoogleCloudPlatform/dee-infra @GoogleCloudPlatform/nodejs-samples-reviewers @GoogleCloudPlatform/cloud-samples-reviewers
 recaptcha_enterprise @GoogleCloudPlatform/dee-infra @GoogleCloudPlatform/nodejs-samples-reviewers @GoogleCloudPlatform/cloud-samples-reviewers
 recaptcha_enterprise/demosite @GoogleCloudPlatform/dee-infra @GoogleCloudPlatform/recaptcha-customer-obsession-reviewers @GoogleCloudPlatform/nodejs-samples-reviewers @GoogleCloudPlatform/cloud-samples-reviewers
 secret-manager @GoogleCloudPlatform/dee-infra @GoogleCloudPlatform/nodejs-samples-reviewers @GoogleCloudPlatform/cloud-samples-reviewers @GoogleCloudPlatform/cloud-secrets-team
diff --git a/tpu/package.json b/tpu/package.json
new file mode 100644
index 00000000000..81edf2e8829
--- /dev/null
+++ b/tpu/package.json
@@ -0,0 +1,23 @@
+{
+    "name": "nodejs-docs-samples-tpu",
+    "license": "Apache-2.0",
+    "author": "Google Inc.",
+    "engines": {
+      "node": ">=16.0.0"
+    },
+    "repository": "googleapis/nodejs-tpu",
+    "private": true,
+    "files": [
+      "*.js"
+    ],
+    "scripts": {
+      "test": "c8 mocha -p -j 2 test --timeout 1200000"
+    },
+    "dependencies": {
+      "@google-cloud/tpu": "^3.5.0"
+    },
+    "devDependencies": {
+      "c8": "^10.0.0",
+      "mocha": "^10.0.0"
+    }
+  }
\ No newline at end of file
diff --git a/tpu/queuedResources/createQueuedResourceStartupScript.js b/tpu/queuedResources/createQueuedResourceStartupScript.js
new file mode 100644
index 00000000000..4ee2decb204
--- /dev/null
+++ b/tpu/queuedResources/createQueuedResourceStartupScript.js
@@ -0,0 +1,130 @@
+/*
+ * Copyright 2024 Google LLC
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *     https://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+
+'use strict';
+
+async function main(
+  nodeName,
+  queuedResourceName,
+  zone,
+  tpuType,
+  tpuSoftwareVersion
+) {
+  // [START tpu_queued_resources_startup_script]
+  // Import the TPU library
+  const {TpuClient} = require('@google-cloud/tpu').v2alpha1;
+  const {Node, NetworkConfig, QueuedResource} =
+    require('@google-cloud/tpu').protos.google.cloud.tpu.v2alpha1;
+
+  // Instantiate a tpuClient
+  const tpuClient = new TpuClient();
+
+  /**
+   * TODO(developer): Update/uncomment these variables before running the sample.
+   */
+  // Project ID or project number of the Google Cloud project, where you want to create queued resource.
+  const projectId = await tpuClient.getProjectId();
+
+  // The name of the network you want the node to connect to. The network should be assigned to your project.
+  const networkName = 'compute-tpu-network';
+
+  // The region of the network, that you want the node to connect to.
+  const region = 'europe-west4';
+
+  // The name for your queued resource.
+  // queuedResourceName = 'queued-resource-1';
+
+  // The name for your node.
+  // nodeName = 'node-name-1';
+
+  // The zone in which to create the node.
+  // For more information about supported TPU types for specific zones,
+  // see https://cloud.google.com/tpu/docs/regions-zones
+  // zone = 'europe-west4-a';
+
+  // The accelerator type that specifies the version and size of the node you want to create.
+  // For more information about supported accelerator types for each TPU version,
+  // see https://cloud.google.com/tpu/docs/system-architecture-tpu-vm#versions.
+  // tpuType = 'v2-8';
+
+  // Software version that specifies the version of the node runtime to install. For more information,
+  // see https://cloud.google.com/tpu/docs/runtimes
+  // tpuSoftwareVersion = 'tpu-vm-tf-2.14.1';
+
+  async function callCreateQueuedResourceStartupScript() {
+    // Create a node
+    const node = new Node({
+      name: nodeName,
+      zone,
+      acceleratorType: tpuType,
+      runtimeVersion: tpuSoftwareVersion,
+      // Define network
+      networkConfig: new NetworkConfig({
+        enableExternalIps: true,
+        network: `projects/${projectId}/global/networks/${networkName}`,
+        subnetwork: `projects/${projectId}/regions/${region}/subnetworks/${networkName}`,
+      }),
+      queuedResource: `projects/${projectId}/locations/${zone}/queuedResources/${queuedResourceName}`,
+      metadata: {
+        // The script updates numpy to the latest version and logs the output to a file.
+        'startup-script': `#!/bin/bash
+    echo "Hello World" > /var/log/hello.log
+    sudo pip3 install --upgrade numpy >> /var/log/hello.log 2>&1`,
+      },
+    });
+
+    // Define parent for requests
+    const parent = `projects/${projectId}/locations/${zone}`;
+
+    // Create queued resource
+    const queuedResource = new QueuedResource({
+      name: queuedResourceName,
+      tpu: {
+        nodeSpec: [
+          {
+            parent,
+            node,
+            nodeId: nodeName,
+          },
+        ],
+      },
+    });
+
+    const request = {
+      parent: `projects/${projectId}/locations/${zone}`,
+      queuedResource,
+      queuedResourceId: queuedResourceName,
+    };
+
+    const [operation] = await tpuClient.createQueuedResource(request);
+
+    // Wait for the create operation to complete.
+    await operation.promise();
+
+    // You can wait until TPU Node is READY,
+    // and check its status using getTpuVm() from `tpu_vm_get` sample.
+    console.log(
+      `Queued resource ${queuedResourceName} with start-up script created.`
+    );
+  }
+  await callCreateQueuedResourceStartupScript();
+  // [END tpu_queued_resources_startup_script]
+}
+
+main(...process.argv.slice(2)).catch(err => {
+  console.error(err);
+  process.exitCode = 1;
+});
diff --git a/tpu/queuedResources/forceDeleteQueuedResource.js b/tpu/queuedResources/forceDeleteQueuedResource.js
new file mode 100644
index 00000000000..e842c39e269
--- /dev/null
+++ b/tpu/queuedResources/forceDeleteQueuedResource.js
@@ -0,0 +1,59 @@
+/*
+ * Copyright 2024 Google LLC
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *     https://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+
+'use strict';
+
+async function main(queuedResourceName, zone) {
+  // [START tpu_queued_resources_delete_force]
+  // Import the TPU library
+  const {TpuClient} = require('@google-cloud/tpu').v2alpha1;
+
+  // Instantiate a tpuClient
+  const tpuClient = new TpuClient();
+
+  /**
+   * TODO(developer): Update/uncomment these variables before running the sample.
+   */
+  // Project ID or project number of the Google Cloud project, where you want to delete node.
+  const projectId = await tpuClient.getProjectId();
+
+  // The name of queued resource.
+  // queuedResourceName = 'queued-resource-1';
+
+  // The zone of your queued resource.
+  // zone = 'europe-west4-a';
+
+  async function callForceDeleteQueuedResource() {
+    const request = {
+      name: `projects/${projectId}/locations/${zone}/queuedResources/${queuedResourceName}`,
+      force: true,
+    };
+
+    const [operation] = await tpuClient.deleteQueuedResource(request);
+
+    // Wait for the delete operation to complete.
+    await operation.promise();
+
+    console.log(`Queued resource ${queuedResourceName} deletion forced.`);
+  }
+  await callForceDeleteQueuedResource();
+  // [END tpu_queued_resources_delete_force]
+}
+
+main(...process.argv.slice(2)).catch(err => {
+  console.error(err);
+  process.exitCode = 1;
+});
diff --git a/tpu/test/.eslintrc b/tpu/test/.eslintrc
new file mode 100644
index 00000000000..e28757c0a59
--- /dev/null
+++ b/tpu/test/.eslintrc
@@ -0,0 +1,3 @@
+---
+env:
+  mocha: true
\ No newline at end of file
diff --git a/tpu/test/createQueuedResourceStartupScript.test.js b/tpu/test/createQueuedResourceStartupScript.test.js
new file mode 100644
index 00000000000..d82f7704744
--- /dev/null
+++ b/tpu/test/createQueuedResourceStartupScript.test.js
@@ -0,0 +1,58 @@
+/*
+ * Copyright 2024 Google LLC
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *     https://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+
+'use strict';
+
+const path = require('path');
+const assert = require('node:assert/strict');
+const {after, describe, it} = require('mocha');
+const cp = require('child_process');
+
+const execSync = cmd => cp.execSync(cmd, {encoding: 'utf-8'});
+const cwd = path.join(__dirname, '..');
+
+describe('TPU queued resource with start-up script', async () => {
+  const queuedResourceName = `queued-resource-startup-script-${Math.floor(Math.random() * 1000 + 1)}`;
+  const nodeName = `node-startup-script-2a2b3c${Math.floor(Math.random() * 1000 + 1)}`;
+  const zone = 'us-east1-d';
+  const tpuType = 'v3-32';
+  const tpuSoftwareVersion = 'tpu-vm-tf-2.14.1';
+
+  after(() => {
+    // Delete queued resource
+    execSync(
+      `node ./queuedResources/forceDeleteQueuedResource.js ${queuedResourceName} ${zone}`,
+      {
+        cwd,
+      }
+    );
+  });
+
+  it('should create queued resource with start-up script', () => {
+    const response = execSync(
+      `node ./queuedResources/createQueuedResourceStartupScript.js ${nodeName} ${queuedResourceName} ${zone} ${tpuType} ${tpuSoftwareVersion}`,
+      {
+        cwd,
+      }
+    );
+
+    assert(
+      response.includes(
+        `Queued resource ${queuedResourceName} with start-up script created.`
+      )
+    );
+  });
+});