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+# # Enzyme constrained models
+
+using COBREXA
+
+# Here we will construct an enzyme constrained variant of the *E. coli* "core"
+# model. We will need the model, which we can download if it is not already present.
+
+import Downloads: download
+
+!isfile("e_coli_core.json") &&
+    download("http://bigg.ucsd.edu/static/models/e_coli_core.json", "e_coli_core.json")
+
+# Additionally to COBREXA and the model format package, we will need a solver
+# -- let's use Tulip here:
+
+import JSONFBCModels
+import Tulip
+
+model = load_model("e_coli_core.json")
+
+# Enzyme constrained models require parameters that are usually not used by
+# conventional constraint based models. These include reaction specific turnover
+# numbers, molar masses of enzymes, and capacity bounds.
+
+import AbstractFBCModels as A