diff --git a/neo/rawio/spikeglxrawio.py b/neo/rawio/spikeglxrawio.py
index 15f969e5d..34e77a6e2 100644
--- a/neo/rawio/spikeglxrawio.py
+++ b/neo/rawio/spikeglxrawio.py
@@ -408,8 +408,12 @@ def extract_stream_info(meta_file, meta):
             # https://github.com/billkarsh/SpikeGLX/blob/15ec8898e17829f9f08c226bf04f46281f106e5f/Markdown/Metadata_30.md#imec
             # We allow also LF streams for NP2.0 because CatGT can produce them
             # See: https://github.com/SpikeInterface/spikeinterface/issues/1949
-            per_channel_gain[:-1] = 1 / 80.
-            gain_factor = float(meta['imAiRangeMax']) / 8192
+            if 'imChan0apGain' in meta:
+                per_channel_gain[:-1] = 1 / float(meta['imChan0apGain'])
+            else:
+                per_channel_gain[:-1] = 1 / 80.
+            max_int = int(meta['imMaxInt']) if 'imMaxInt' in meta else 8192
+            gain_factor = float(meta['imAiRangeMax']) / max_int
             channel_gains = gain_factor * per_channel_gain * 1e6
         else:
             raise NotImplementedError('This meta file version of spikeglx'