It is possible the 22 Ohm resistors on the USB data lines are redundant, due to misleading reference schematics. To investigate.
A report from one of the users received on Riot:
I am watching some videos about USB, one seems to tell that 22 r resistors on the USB data lines are not needed
https://youtu.be/vwlXUOY7KY0?t=269
They are on the Nitrokey_Pro_v2_schematics.pdf, and I think I saw them on other board designs
That seemed weird, but why not. Then I saw the video suggesting that a "reference" design included them without mentioning it was a workaround because an improper ESD part was used