From 3ce3c4c6c2d3818b1a93c845056d8d3113306ea4 Mon Sep 17 00:00:00 2001 From: Jeremy Wildfire Date: Tue, 12 Oct 2021 12:04:16 -0400 Subject: [PATCH 01/50] very rough cm prototype --- DESCRIPTION | 2 +- NAMESPACE | 1 + R/init_cmExplorer.R | 42 ++++++++++++++++++++++++++++++++++++ inst/config/cmExplorer.yaml | 18 ++++++++++++++++ inst/config/cmTimelines.yaml | 17 +++++++++++++++ man/init_cmExplorer.Rd | 19 ++++++++++++++++ 6 files changed, 98 insertions(+), 1 deletion(-) create mode 100644 R/init_cmExplorer.R create mode 100644 inst/config/cmExplorer.yaml create mode 100644 inst/config/cmTimelines.yaml create mode 100644 man/init_cmExplorer.Rd diff --git a/DESCRIPTION b/DESCRIPTION index 4b890a2..bcf0662 100644 --- a/DESCRIPTION +++ b/DESCRIPTION @@ -15,7 +15,7 @@ BugReports: https://github.com/SafetyGraphics/safetyCharts/issues License: MIT + file LICENSE Encoding: UTF-8 LazyData: true -RoxygenNote: 7.1.1 +RoxygenNote: 7.1.2 Roxygen: list(markdown = TRUE) Imports: dplyr, diff --git a/NAMESPACE b/NAMESPACE index a994227..66d85e2 100644 --- a/NAMESPACE +++ b/NAMESPACE @@ -4,6 +4,7 @@ export(demogRTF_server) export(demogRTF_table) export(demogRTF_ui) export(init_aeExplorer) +export(init_cmExplorer) export(init_paneledOutlierExplorer) export(init_safetyOutlierExplorer) export(init_safetyResultsOverTime) diff --git a/R/init_cmExplorer.R b/R/init_cmExplorer.R new file mode 100644 index 0000000..0505831 --- /dev/null +++ b/R/init_cmExplorer.R @@ -0,0 +1,42 @@ +#' Initialize Settings for Adverse Event Explorer widget +#' +#' @param data labs data structured as one record per person per visit per measurement. See details for column requirements. +#' @param settings named list of settings +#' +#' @return returns list with data and settings +#' +#' @export + + +init_cmExplorer <- function(data, settings) { + print("CM TIME") + # Merge treatment with adverse events. + dm_sub <- data$dm %>% select(settings[["dm"]][["id_col"]], settings[["dm"]][["treatment_col"]]) + anly <- dm_sub %>% left_join(data$cm) # left join to keep all rows in dm (even if there were no AEs) + + settings <- c(settings$cm, settings$labs) + + settings$variables <- list( + major = settings[["bodsys_col"]], + minor = settings[["term_col"]], + group = settings[["trt_col"]], + id = paste0(settings[["id_col"]]), + filters = list(), + details = list() + ) + + settings$variableOptions <- list( + group = c( + settings[["treatment_values--group1"]], + settings[["treatment_values--group2"]] + ) + ) + + settings$defaults <- list( + placeholderFlag = list( + valueCol = settings[["bodsys_col"]], + values = c("", NA, NULL) + ) + ) + return(list(data = anly, settings = settings)) +} diff --git a/inst/config/cmExplorer.yaml b/inst/config/cmExplorer.yaml new file mode 100644 index 0000000..3988cb9 --- /dev/null +++ b/inst/config/cmExplorer.yaml @@ -0,0 +1,18 @@ +env: safetyGraphics +label: Conmeds Explorer +type: htmlwidget +package: safetyCharts +export: true +order: 2 +domain: + - cm + - dm +workflow: + init: init_cmExplorer + widget: aeExplorer +links: + Homepage: https://github.com/RhoInc/aeexplorer + Wiki: https://github.com/RhoInc/aeexplorer/wiki + Issues: https://github.com/RhoInc/aeexplorer/issues + Demo: https://rhoinc.github.io/aeexplorer/test-page/ + safetyCharts: https://github.com/SafetyGraphics/safetycharts \ No newline at end of file diff --git a/inst/config/cmTimelines.yaml b/inst/config/cmTimelines.yaml new file mode 100644 index 0000000..ae8517f --- /dev/null +++ b/inst/config/cmTimelines.yaml @@ -0,0 +1,17 @@ +env: safetyGraphics +label: Com Meds Timelines +type: htmlwidget +package: safetyCharts +export: false +order: 3 +domain: + - cm +workflow: + widget: aeTimelines +links: + Homepage: https://github.com/RhoInc/ae-timelines + Wiki: https://github.com/RhoInc/ae-timelines/wiki + Issues: https://github.com/RhoInc/ae-timelines/issues + Demo: https://rhoinc.github.io/ae-timelines/test-page/ + safetyCharts: https://github.com/SafetyGraphics/safetycharts + diff --git a/man/init_cmExplorer.Rd b/man/init_cmExplorer.Rd new file mode 100644 index 0000000..3b71083 --- /dev/null +++ b/man/init_cmExplorer.Rd @@ -0,0 +1,19 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/init_cmExplorer.R +\name{init_cmExplorer} +\alias{init_cmExplorer} +\title{Initialize Settings for Adverse Event Explorer widget} +\usage{ +init_cmExplorer(data, settings) +} +\arguments{ +\item{data}{labs data structured as one record per person per visit per measurement. See details for column requirements.} + +\item{settings}{named list of settings} +} +\value{ +returns list with data and settings +} +\description{ +Initialize Settings for Adverse Event Explorer widget +} From 6b59c9a14a23fe3c83039cf2e8b53d88eb63dcf9 Mon Sep 17 00:00:00 2001 From: Maya Gans Date: Fri, 15 Apr 2022 06:48:09 -0700 Subject: [PATCH 02/50] scaffolding paneledOutlierExplorer --- R/paneled_outlier_explorer.R | 52 ++++++++++++++++++++++++++++++++++++ 1 file changed, 52 insertions(+) create mode 100644 R/paneled_outlier_explorer.R diff --git a/R/paneled_outlier_explorer.R b/R/paneled_outlier_explorer.R new file mode 100644 index 0000000..07fe027 --- /dev/null +++ b/R/paneled_outlier_explorer.R @@ -0,0 +1,52 @@ +#' Paneled Outlier Explorer +#' +#' @import htmlwidgets +#' +#' @export +#' @example paneledOutlierExplorer(init_paneledOutlierExplorer(adbds, settings)) +paneledOutlierExplorer <- function(data, settings, width = NULL, height = NULL, elementId = NULL) { + + # forward options using x + x = list( + data = data, + settings = settings + ) + + # create widget + htmlwidgets::createWidget( + name = 'paneledOutlierExplorer', + x, + width = width, + height = height, + package = 'paneledOutlierExplorer', + elementId = elementId + ) +} + +#' Shiny bindings for paneledOutlierExplorer +#' +#' Output and render functions for using paneledOutlierExplorer within Shiny +#' applications and interactive Rmd documents. +#' +#' @param outputId output variable to read from +#' @param width,height Must be a valid CSS unit (like \code{'100\%'}, +#' \code{'400px'}, \code{'auto'}) or a number, which will be coerced to a +#' string and have \code{'px'} appended. +#' @param expr An expression that generates a paneledOutlierExplorer +#' @param env The environment in which to evaluate \code{expr}. +#' @param quoted Is \code{expr} a quoted expression (with \code{quote()})? This +#' is useful if you want to save an expression in a variable. +#' +#' @name paneledOutlierExplorer-shiny +#' +#' @export +paneledOutlierExplorerOutput <- function(outputId, width = '100%', height = '400px'){ + htmlwidgets::shinyWidgetOutput(outputId, 'paneledOutlierExplorer', width, height, package = 'paneledOutlierExplorer') +} + +#' @rdname paneledOutlierExplorer-shiny +#' @export +renderPaneledOutlierExplorer <- function(expr, env = parent.frame(), quoted = FALSE) { + if (!quoted) { expr <- substitute(expr) } # force quoted + htmlwidgets::shinyRenderWidget(expr, paneledOutlierExplorerOutput, env, quoted = TRUE) +} From a85cd8d6b653c8220a44b4bec99f103329faa3e2 Mon Sep 17 00:00:00 2001 From: Maya Gans Date: Fri, 15 Apr 2022 06:50:33 -0700 Subject: [PATCH 03/50] use init as input --- R/paneled_outlier_explorer.R | 6 +++--- 1 file changed, 3 insertions(+), 3 deletions(-) diff --git a/R/paneled_outlier_explorer.R b/R/paneled_outlier_explorer.R index 07fe027..2a4be09 100644 --- a/R/paneled_outlier_explorer.R +++ b/R/paneled_outlier_explorer.R @@ -4,12 +4,12 @@ #' #' @export #' @example paneledOutlierExplorer(init_paneledOutlierExplorer(adbds, settings)) -paneledOutlierExplorer <- function(data, settings, width = NULL, height = NULL, elementId = NULL) { +paneledOutlierExplorer <- function(data, width = NULL, height = NULL, elementId = NULL) { # forward options using x x = list( - data = data, - settings = settings + data = data$data, + settings = data$settings ) # create widget From a0eed9b6d1b53528ca2594955cf5ccffe201b75c Mon Sep 17 00:00:00 2001 From: Maya Gans Date: Fri, 15 Apr 2022 11:08:54 -0400 Subject: [PATCH 04/50] adding static settings, will turn into variables once this works --- R/init_safetyOutlierExplorer.R | 89 +++++++++++++++++++++++++++++----- 1 file changed, 77 insertions(+), 12 deletions(-) diff --git a/R/init_safetyOutlierExplorer.R b/R/init_safetyOutlierExplorer.R index 1eea5cd..f845d4d 100644 --- a/R/init_safetyOutlierExplorer.R +++ b/R/init_safetyOutlierExplorer.R @@ -1,4 +1,4 @@ -#' Initialize Settings for Safety Outlier Explorer widget +#' Initialize Settings for Paneled Outlier Explorer widget #' #' @param data labs data structured as one record per person per visit per measurement. See details for column requirements. #' @param settings named list of settings @@ -7,15 +7,80 @@ #' #' @export -init_safetyOutlierExplorer <- function(data, settings) { - settings$time_cols <- data_frame( - value_col = c(settings[["visit_col"]], settings[["studyday_col"]]), - type = c("ordinal", "linear"), - order_col = c(settings[["visitn_col"]], "null"), - label = c("Visit", "Study Day"), - rotate_tick_labels = c(T, F), - vertical_space = c(100, 0) - ) - - return(list(data = data, settings = settings)) +init_paneledOutlierExplorer <- function(data) { + + settings = list( + measure_col = 'TEST', + time_cols = list( + list( + value_col = "VISIT", + type = "ordinal", + order = NULL, + order_col = "VISITNUM", + label = "VISIT", + rotate_tick_labels = TRUE, + vertical_space = 75 + ), + list( + value_col = 'DY', + type = 'linear', + order = NULL, + order_col = 'DY', + label = 'Study Day', + rotate_tick_labels = FALSE, + vertical_space = 0 + ) + ), + value_col = 'STRESN', + id_col = 'USUBJID', + unit_col = 'STRESU', + lln_col = 'STNRLO', + uln_col = 'STNRHI', + measures = NULL, + filters = NULL, + multiples_sizing = list( + width = 350, + height = 175 + ), + inliers = FALSE, + normal_range_method = 'LLN-ULN', + normal_range_sd = 1.96, + normal_range_quantile_low = 0.05, + normal_range_quantile_high = 0.95, + visits_without_data = FALSE, + unscheduled_visits = FALSE, + unscheduled_visit_pattern = '/unscheduled|early termination/i', + unscheduled_visit_values = NULL, + x = list( + type = NULL, + column = NULL, + label = NULL + ), + y = list( + type = 'linear', + column = NULL, + label = '' + ), + marks = list( + list( + type = 'line', + per = NULL, #sync to [ id_col ] and [ measure_col ] + attributes = list( + 'stroke-width' = 1, + 'stroke-opacity' = 0.2, + stroke = 'black' + ) + ) + ), + resizable = FALSE, + scale_text = FALSE, + margin = list( + bottom = 0, + left = 50 + ), + gridlines = 'xy' + ) + + return(list(data = data, settings = settings)) + } From 5b21d05645d8e6163eeb52868e358cc8f775deef Mon Sep 17 00:00:00 2001 From: Maya Gans Date: Fri, 15 Apr 2022 11:28:47 -0400 Subject: [PATCH 05/50] abstracting settings --- R/init_safetyOutlierExplorer.R | 118 ++++++++++++++++++++++----------- R/paneled_outlier_explorer.R | 2 +- 2 files changed, 82 insertions(+), 38 deletions(-) diff --git a/R/init_safetyOutlierExplorer.R b/R/init_safetyOutlierExplorer.R index f845d4d..2a5726b 100644 --- a/R/init_safetyOutlierExplorer.R +++ b/R/init_safetyOutlierExplorer.R @@ -9,62 +9,106 @@ init_paneledOutlierExplorer <- function(data) { + x_value_col = "VISIT" + x_type = 'ordinal' + x_order = NULL + x_order_col = 'VISITNUM' + x_label = "VISIT" + x_rotate_tick_labels = TRUE + x_vertical_space = 75 + + value_col = 'DY' + type = 'linear' + order = NULL + order_col = 'DY' + label = 'Study Day' + rotate_tick_labels = FALSE + vertical_space = 0 + + y_value_col = "DY" + y_type = 'linear' + y_order = NULL + y_order_col = 'DY' + y_label = "Study Day" + y_rotate_tick_labels = FALSE + y_vertical_space = 0 + + value_col = 'STRESN' + id_col = 'USUBJID' + unit_col = 'STRESU' + lln_col = 'STNRLO' + uln_col = 'STNRHI' + measures = NULL + filters = NULL + + multiples_sizing_width = 350 + mutliples_sizing_height = 175 + inliers = FALSE + normal_range_method = 'LLN-ULN' + normal_range_sd = 1.96 + normal_range_quantile_low = 0.05 + normal_range_quantile_high = 0.95 + visits_without_data = FALSE + unscheduled_visits = FALSE + unscheduled_visit_pattern = '/unscheduled|early termination/i' + unscheduled_visit_values = NULL + settings = list( measure_col = 'TEST', time_cols = list( list( - value_col = "VISIT", - type = "ordinal", - order = NULL, - order_col = "VISITNUM", - label = "VISIT", - rotate_tick_labels = TRUE, - vertical_space = 75 + value_col = x_value_col, + type = x_type, + order = x_order, + order_col = x_order_col, + label = x_label, + rotate_tick_labels = x_rotate_tick_labels, + vertical_space = x_vertical_space ), list( - value_col = 'DY', - type = 'linear', - order = NULL, - order_col = 'DY', - label = 'Study Day', - rotate_tick_labels = FALSE, - vertical_space = 0 + value_col = y_value_col, + type = y_type, + order = y_order, + order_col = y_order_col, + label = y_label, + rotate_tick_labels = y_rotate_tick_labels, + vertical_space = y_vertical_space ) ), - value_col = 'STRESN', - id_col = 'USUBJID', - unit_col = 'STRESU', - lln_col = 'STNRLO', - uln_col = 'STNRHI', - measures = NULL, - filters = NULL, + value_col = value_col, + id_col = id_col, + unit_col = unit_col, + lln_col = lln_col, + uln_col = uln_col, + measures = measures, + filters = filters, multiples_sizing = list( width = 350, height = 175 ), - inliers = FALSE, - normal_range_method = 'LLN-ULN', - normal_range_sd = 1.96, - normal_range_quantile_low = 0.05, - normal_range_quantile_high = 0.95, - visits_without_data = FALSE, - unscheduled_visits = FALSE, - unscheduled_visit_pattern = '/unscheduled|early termination/i', - unscheduled_visit_values = NULL, + inliers = inliers, + normal_range_method = normal_range_method, + normal_range_sd = normal_range_sd, + normal_range_quantile_low = normal_range_quantile_low, + normal_range_quantile_high = normal_range_quantile_high, + visits_without_data = visits_without_data, + unscheduled_visits = unscheduled_visits, + unscheduled_visit_pattern = unscheduled_visit_pattern, + unscheduled_visit_values = unscheduled_visit_values, # takes precedence over unscheduled_visit_pattern visits_without_data: false, x = list( - type = NULL, - column = NULL, - label = NULL + type = x_type, #sync to [ time_cols[0].type ] + column = x_value_col, #sync to [ time_cols[0].value_col ] + label = x_label #sync to [ time_cols[0].label ] ), y = list( - type = 'linear', - column = NULL, - label = '' + type = y_type, + column = y_value_col, # sync to [ value_col ] + label = y_label ), marks = list( list( type = 'line', - per = NULL, #sync to [ id_col ] and [ measure_col ] + per = id_col, #sync to [ id_col ] and [ measure_col ] attributes = list( 'stroke-width' = 1, 'stroke-opacity' = 0.2, diff --git a/R/paneled_outlier_explorer.R b/R/paneled_outlier_explorer.R index 2a4be09..b155321 100644 --- a/R/paneled_outlier_explorer.R +++ b/R/paneled_outlier_explorer.R @@ -9,7 +9,7 @@ paneledOutlierExplorer <- function(data, width = NULL, height = NULL, elementId # forward options using x x = list( data = data$data, - settings = data$settings + settings = jsonlite::toJSON(data$settings) ) # create widget From 95d4fbcbe988508736a75f8fabab8dc07d6f9994 Mon Sep 17 00:00:00 2001 From: Maya Gans Date: Fri, 15 Apr 2022 11:32:42 -0400 Subject: [PATCH 06/50] adding settings as arguments --- R/init_safetyOutlierExplorer.R | 80 +++++++++++++++------------------- 1 file changed, 35 insertions(+), 45 deletions(-) diff --git a/R/init_safetyOutlierExplorer.R b/R/init_safetyOutlierExplorer.R index 2a5726b..ae64137 100644 --- a/R/init_safetyOutlierExplorer.R +++ b/R/init_safetyOutlierExplorer.R @@ -7,51 +7,41 @@ #' #' @export -init_paneledOutlierExplorer <- function(data) { - - x_value_col = "VISIT" - x_type = 'ordinal' - x_order = NULL - x_order_col = 'VISITNUM' - x_label = "VISIT" - x_rotate_tick_labels = TRUE - x_vertical_space = 75 - - value_col = 'DY' - type = 'linear' - order = NULL - order_col = 'DY' - label = 'Study Day' - rotate_tick_labels = FALSE - vertical_space = 0 - - y_value_col = "DY" - y_type = 'linear' - y_order = NULL - y_order_col = 'DY' - y_label = "Study Day" - y_rotate_tick_labels = FALSE - y_vertical_space = 0 - - value_col = 'STRESN' - id_col = 'USUBJID' - unit_col = 'STRESU' - lln_col = 'STNRLO' - uln_col = 'STNRHI' - measures = NULL - filters = NULL - - multiples_sizing_width = 350 - mutliples_sizing_height = 175 - inliers = FALSE - normal_range_method = 'LLN-ULN' - normal_range_sd = 1.96 - normal_range_quantile_low = 0.05 - normal_range_quantile_high = 0.95 - visits_without_data = FALSE - unscheduled_visits = FALSE - unscheduled_visit_pattern = '/unscheduled|early termination/i' - unscheduled_visit_values = NULL +init_paneledOutlierExplorer <- function( + data, + x_value_col = "VISIT", + x_type = 'ordinal', + x_order = NULL, + x_order_col = 'VISITNUM', + x_label = "VISIT", + x_rotate_tick_labels = TRUE, + x_vertical_space = 75, + y_value_col = 'DY', + y_type = 'linear', + y_order = NULL, + y_order_col = 'DY', + y_label = 'Study Day', + y_rotate_tick_labels = FALSE, + y_vertical_space = 0, + value_col = 'STRESN', + id_col = 'USUBJID', + unit_col = 'STRESU', + lln_col = 'STNRLO', + uln_col = 'STNRHI', + measures = NULL, + filters = NULL, + multiples_sizing_width = 350, + mutliples_sizing_height = 175, + inliers = FALSE, + normal_range_method = 'LLN-ULN', + normal_range_sd = 1.96, + normal_range_quantile_low = 0.05, + normal_range_quantile_high = 0.95, + visits_without_data = FALSE, + unscheduled_visits = FALSE, + unscheduled_visit_pattern = '/unscheduled|early termination/i', + unscheduled_visit_values = NULL +) { settings = list( measure_col = 'TEST', From a4512a0dc987c2967f19a9ea332c004cc964c690 Mon Sep 17 00:00:00 2001 From: Jeremy Wildfire Date: Sat, 16 Apr 2022 11:48:12 -0400 Subject: [PATCH 07/50] refactor to use wrapper for --- NAMESPACE | 1 + R/init_safetyOutlierExplorer.R | 125 ++++----------------------------- R/paneled_outlier_explorer.R | 52 -------------- 3 files changed, 14 insertions(+), 164 deletions(-) delete mode 100644 R/paneled_outlier_explorer.R diff --git a/NAMESPACE b/NAMESPACE index b8ff9c6..e1a00ce 100644 --- a/NAMESPACE +++ b/NAMESPACE @@ -15,6 +15,7 @@ export(init_safetyResultsOverTime) export(init_safetyShiftPlot) export(lab_distribution_server) export(lab_distribution_ui) +export(paneledOutlierExplorer) export(render_widget) export(safetyOutlierExplorer_server) export(safetyOutlierExplorer_ui) diff --git a/R/init_safetyOutlierExplorer.R b/R/init_safetyOutlierExplorer.R index ae64137..2d79694 100644 --- a/R/init_safetyOutlierExplorer.R +++ b/R/init_safetyOutlierExplorer.R @@ -1,4 +1,4 @@ -#' Initialize Settings for Paneled Outlier Explorer widget +#' Initialize Settings for Safety Outlier Explorer widget #' #' @param data labs data structured as one record per person per visit per measurement. See details for column requirements. #' @param settings named list of settings @@ -7,114 +7,15 @@ #' #' @export -init_paneledOutlierExplorer <- function( - data, - x_value_col = "VISIT", - x_type = 'ordinal', - x_order = NULL, - x_order_col = 'VISITNUM', - x_label = "VISIT", - x_rotate_tick_labels = TRUE, - x_vertical_space = 75, - y_value_col = 'DY', - y_type = 'linear', - y_order = NULL, - y_order_col = 'DY', - y_label = 'Study Day', - y_rotate_tick_labels = FALSE, - y_vertical_space = 0, - value_col = 'STRESN', - id_col = 'USUBJID', - unit_col = 'STRESU', - lln_col = 'STNRLO', - uln_col = 'STNRHI', - measures = NULL, - filters = NULL, - multiples_sizing_width = 350, - mutliples_sizing_height = 175, - inliers = FALSE, - normal_range_method = 'LLN-ULN', - normal_range_sd = 1.96, - normal_range_quantile_low = 0.05, - normal_range_quantile_high = 0.95, - visits_without_data = FALSE, - unscheduled_visits = FALSE, - unscheduled_visit_pattern = '/unscheduled|early termination/i', - unscheduled_visit_values = NULL -) { - - settings = list( - measure_col = 'TEST', - time_cols = list( - list( - value_col = x_value_col, - type = x_type, - order = x_order, - order_col = x_order_col, - label = x_label, - rotate_tick_labels = x_rotate_tick_labels, - vertical_space = x_vertical_space - ), - list( - value_col = y_value_col, - type = y_type, - order = y_order, - order_col = y_order_col, - label = y_label, - rotate_tick_labels = y_rotate_tick_labels, - vertical_space = y_vertical_space - ) - ), - value_col = value_col, - id_col = id_col, - unit_col = unit_col, - lln_col = lln_col, - uln_col = uln_col, - measures = measures, - filters = filters, - multiples_sizing = list( - width = 350, - height = 175 - ), - inliers = inliers, - normal_range_method = normal_range_method, - normal_range_sd = normal_range_sd, - normal_range_quantile_low = normal_range_quantile_low, - normal_range_quantile_high = normal_range_quantile_high, - visits_without_data = visits_without_data, - unscheduled_visits = unscheduled_visits, - unscheduled_visit_pattern = unscheduled_visit_pattern, - unscheduled_visit_values = unscheduled_visit_values, # takes precedence over unscheduled_visit_pattern visits_without_data: false, - x = list( - type = x_type, #sync to [ time_cols[0].type ] - column = x_value_col, #sync to [ time_cols[0].value_col ] - label = x_label #sync to [ time_cols[0].label ] - ), - y = list( - type = y_type, - column = y_value_col, # sync to [ value_col ] - label = y_label - ), - marks = list( - list( - type = 'line', - per = id_col, #sync to [ id_col ] and [ measure_col ] - attributes = list( - 'stroke-width' = 1, - 'stroke-opacity' = 0.2, - stroke = 'black' - ) - ) - ), - resizable = FALSE, - scale_text = FALSE, - margin = list( - bottom = 0, - left = 50 - ), - gridlines = 'xy' - ) - - return(list(data = data, settings = settings)) - -} +init_safetyOutlierExplorer <- function(data, settings) { + settings$time_cols <- data_frame( + value_col = c(settings[["visit_col"]], settings[["studyday_col"]]), + type = c("ordinal", "linear"), + order_col = c(settings[["visitn_col"]], "null"), + label = c("Visit", "Study Day"), + rotate_tick_labels = c(T, F), + vertical_space = c(100, 0) + ) + + return(list(data = data, settings = settings)) +} \ No newline at end of file diff --git a/R/paneled_outlier_explorer.R b/R/paneled_outlier_explorer.R deleted file mode 100644 index b155321..0000000 --- a/R/paneled_outlier_explorer.R +++ /dev/null @@ -1,52 +0,0 @@ -#' Paneled Outlier Explorer -#' -#' @import htmlwidgets -#' -#' @export -#' @example paneledOutlierExplorer(init_paneledOutlierExplorer(adbds, settings)) -paneledOutlierExplorer <- function(data, width = NULL, height = NULL, elementId = NULL) { - - # forward options using x - x = list( - data = data$data, - settings = jsonlite::toJSON(data$settings) - ) - - # create widget - htmlwidgets::createWidget( - name = 'paneledOutlierExplorer', - x, - width = width, - height = height, - package = 'paneledOutlierExplorer', - elementId = elementId - ) -} - -#' Shiny bindings for paneledOutlierExplorer -#' -#' Output and render functions for using paneledOutlierExplorer within Shiny -#' applications and interactive Rmd documents. -#' -#' @param outputId output variable to read from -#' @param width,height Must be a valid CSS unit (like \code{'100\%'}, -#' \code{'400px'}, \code{'auto'}) or a number, which will be coerced to a -#' string and have \code{'px'} appended. -#' @param expr An expression that generates a paneledOutlierExplorer -#' @param env The environment in which to evaluate \code{expr}. -#' @param quoted Is \code{expr} a quoted expression (with \code{quote()})? This -#' is useful if you want to save an expression in a variable. -#' -#' @name paneledOutlierExplorer-shiny -#' -#' @export -paneledOutlierExplorerOutput <- function(outputId, width = '100%', height = '400px'){ - htmlwidgets::shinyWidgetOutput(outputId, 'paneledOutlierExplorer', width, height, package = 'paneledOutlierExplorer') -} - -#' @rdname paneledOutlierExplorer-shiny -#' @export -renderPaneledOutlierExplorer <- function(expr, env = parent.frame(), quoted = FALSE) { - if (!quoted) { expr <- substitute(expr) } # force quoted - htmlwidgets::shinyRenderWidget(expr, paneledOutlierExplorerOutput, env, quoted = TRUE) -} From 7cc90aea6b1dc5602847d4d2ba408673beb1dc42 Mon Sep 17 00:00:00 2001 From: Jeremy Wildfire Date: Sat, 16 Apr 2022 11:48:23 -0400 Subject: [PATCH 08/50] refactor to use wrapper for --- R/paneledOutlierExplorer.R | 115 ++++++ docs/404.html | 148 +++++++ docs/LICENSE-text.html | 150 +++++++ docs/LICENSE.html | 154 ++++++++ docs/authors.html | 147 +++++++ docs/bootstrap-toc.css | 60 +++ docs/bootstrap-toc.js | 159 ++++++++ docs/docsearch.css | 148 +++++++ docs/docsearch.js | 85 ++++ docs/index.html | 146 +++++++ docs/link.svg | 12 + docs/news/index.html | 163 ++++++++ docs/pkgdown.css | 367 ++++++++++++++++++ docs/pkgdown.js | 108 ++++++ docs/pkgdown.yml | 6 + docs/reference/QT_OutlierExplorer_server.html | 177 +++++++++ docs/reference/QT_OutlierExplorer_ui.html | 165 ++++++++ docs/reference/QT_Outlier_Explorer.html | 183 +++++++++ docs/reference/Rplot001.png | Bin 0 -> 34966 bytes docs/reference/Rplot002.png | Bin 0 -> 38917 bytes docs/reference/Rplot003.png | Bin 0 -> 56259 bytes docs/reference/demogRTF_server.html | 177 +++++++++ docs/reference/demogRTF_table.html | 310 +++++++++++++++ docs/reference/demogRTF_ui.html | 165 ++++++++ docs/reference/hepExplorer.html | 232 +++++++++++ docs/reference/index.html | 323 +++++++++++++++ docs/reference/init_aeExplorer.html | 169 ++++++++ docs/reference/init_aeTimelines.html | 169 ++++++++ .../init_paneledOutlierExplorer.html | 169 ++++++++ .../reference/init_safetyOutlierExplorer.html | 169 ++++++++ .../reference/init_safetyResultsOverTime.html | 169 ++++++++ docs/reference/init_safetyShiftPlot.html | 169 ++++++++ docs/reference/lab_distribution_server.html | 177 +++++++++ docs/reference/lab_distribution_ui.html | 165 ++++++++ docs/reference/meta_aes.html | 173 +++++++++ docs/reference/meta_dm.html | 173 +++++++++ docs/reference/meta_ecg.html | 173 +++++++++ docs/reference/meta_hepExplorer.html | 173 +++++++++ docs/reference/meta_labs.html | 173 +++++++++ docs/reference/render_widget.html | 170 ++++++++ .../safetyOutlierExplorer_server.html | 177 +++++++++ docs/reference/safetyOutlierExplorer_ui.html | 165 ++++++++ docs/reference/safety_outlier_explorer-1.png | Bin 0 -> 514205 bytes docs/reference/safety_outlier_explorer.html | 191 +++++++++ docs/reference/safety_results_over_time-1.png | Bin 0 -> 114180 bytes docs/reference/safety_results_over_time-2.png | Bin 0 -> 116774 bytes docs/reference/safety_results_over_time-3.png | Bin 0 -> 150642 bytes docs/reference/safety_results_over_time.html | 218 +++++++++++ docs/reference/tendril_chart.html | 182 +++++++++ man/paneledOutlierExplorer.Rd | 81 ++++ 50 files changed, 7105 insertions(+) create mode 100644 R/paneledOutlierExplorer.R create mode 100644 docs/404.html create mode 100644 docs/LICENSE-text.html create mode 100644 docs/LICENSE.html create mode 100644 docs/authors.html create mode 100644 docs/bootstrap-toc.css create mode 100644 docs/bootstrap-toc.js create mode 100644 docs/docsearch.css create mode 100644 docs/docsearch.js create mode 100644 docs/index.html create mode 100644 docs/link.svg create mode 100644 docs/news/index.html create mode 100644 docs/pkgdown.css create mode 100644 docs/pkgdown.js create mode 100644 docs/pkgdown.yml create mode 100644 docs/reference/QT_OutlierExplorer_server.html create mode 100644 docs/reference/QT_OutlierExplorer_ui.html create mode 100644 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docs/reference/meta_dm.html create mode 100644 docs/reference/meta_ecg.html create mode 100644 docs/reference/meta_hepExplorer.html create mode 100644 docs/reference/meta_labs.html create mode 100644 docs/reference/render_widget.html create mode 100644 docs/reference/safetyOutlierExplorer_server.html create mode 100644 docs/reference/safetyOutlierExplorer_ui.html create mode 100644 docs/reference/safety_outlier_explorer-1.png create mode 100644 docs/reference/safety_outlier_explorer.html create mode 100644 docs/reference/safety_results_over_time-1.png create mode 100644 docs/reference/safety_results_over_time-2.png create mode 100644 docs/reference/safety_results_over_time-3.png create mode 100644 docs/reference/safety_results_over_time.html create mode 100644 docs/reference/tendril_chart.html create mode 100644 man/paneledOutlierExplorer.Rd diff --git a/R/paneledOutlierExplorer.R b/R/paneledOutlierExplorer.R new file mode 100644 index 0000000..0c96a1c --- /dev/null +++ b/R/paneledOutlierExplorer.R @@ -0,0 +1,115 @@ +#' Make standalone paneledOutlierExplorer html widget +#' +#' Convience mapping of render_widget for paneledOutlierExplorer. +#' +#' @details The [data](https://github.com/Rhoinc/paneled-outlier-explorer/wiki/Data-Guidelines) and [mapping](https://github.com/RhoInc/paneled-outlier-explorer/wiki/Configuration) should match the specs described in the [paneledOutlierExplorer](https://github.com/rhoinc/paneled-outlier-explorer/wiki/Configuration) javascript library. Items passed in ... are added to mapping, and then the list is converted to json via `jsonlite::toJSON(mapping, auto_unbox=TRUE, null="null")`. +#' +#' The default mapping shown below is designed to work with data in the CDISC ADaM format (like `safetydata::adam_adlbc`). +#' +#' ``` +#' mapping <- list( +#' measure_col = 'PARAM', +#' time_cols = list( +#' list( +#' value_col = "VISIT", +#' order_col = "VISITNUM", +#' label = "VISIT", +#' type = 'ordinal', +#' label="Visit", +#' rotate_tick_labels = TRUE, +#' vertical_space = 75 +#' ), +#' list( +#' value_col = "ADY", +#' order_col = "ADY", +#' label = "Study Day", +#' type = 'linear', +#' label="Visit", +#' rotate_tick_labels = FALSE, +#' vertical_space = 0 +#' ) +#' ), +#' value_col = 'AVAL', +#' id_col = 'USUBJID', +#' lln_col = 'A1LO', +#' uln_col = 'A1HI' +#' ) +#' ``` +#' +#' Parameters that are not included in the default mapping can be accessed via ...; Key options and defaults for safetyData::adam_adlbc shown below: +#' +#' - `filters`: list of columns to be included as data filters formatted as `filters=c("SEX","AGEGR1")``) +#' +#' For more options see the [full specs](https://github.com/rhoinc/paneled-outlier-explorer/wiki/Configuration) in the javascript library. +#' +#' @examples +#' \dontrun{ +#' # Render widget with defaults +#' paneledOutlierExplorer() +#' +#' # Add Sex and Age Filters +#' paneledOutlierExplorer( +#' filters=list( +#' list(value_col="SEX"), +#' list(value_col="AGEGR1",label="Age") +#' ) +#' ) +#' +#' # customize panel size (in pixels) +#' paneledOutlierExplorer(multiples_sizing=list("width"= 500,"height"= 300)) +#' +#' # customize default normal range +#' paneledOutlierExplorer( +#' normal_range_method = 'quantiles', +#' normal_range_quantile_low = 0.2, +#' normal_range_quantile_high = 0.8, +#' ) +#' } +#' @param df data frame containing lab data used to render for paneledOutlierExplorer. Default is safetyData::adam_adlbc. +#' @param mapping named list with the current data mappings. See details for default mapping. +#' @param ... additional options to be added to mapping. Will overwrite mapping. +#' +#' @importFrom purrr list_modify +#' +#' @export +#' + +paneledOutlierExplorer <- function(df=safetyData::adam_adlbc, mapping=NULL, ...){ + if(is.null(mapping)){ + mapping <- list( + measure_col = 'PARAM', + time_cols = list( + list( + value_col = "VISIT", + order_col = "VISITNUM", + label = "VISIT", + type = 'ordinal', + label="Visit", + rotate_tick_labels = TRUE, + vertical_space = 75 + ), + list( + value_col = "ADY", + order_col = "ADY", + label = "Study Day", + type = 'linear', + label="Visit", + rotate_tick_labels = FALSE, + vertical_space = 0 + ) + ), + value_col = 'AVAL', + id_col = 'USUBJID', + lln_col = 'A1LO', + uln_col = 'A1HI' + ) + } + + # add ... to mapping + if(length(list(...))>0){ + mapping <- purrr::list_modify(mapping, !!!list(...)) + } + + # render widget as standalone html page + render_widget("paneledOutlierExplorer" ,df, mapping) +} diff --git a/docs/404.html b/docs/404.html new file mode 100644 index 0000000..cdb5801 --- /dev/null +++ b/docs/404.html @@ -0,0 +1,148 @@ + + + + + + + + +Page not found (404) • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
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+ + + + + + + + diff --git a/docs/bootstrap-toc.css b/docs/bootstrap-toc.css new file mode 100644 index 0000000..5a85941 --- /dev/null +++ b/docs/bootstrap-toc.css @@ -0,0 +1,60 @@ +/*! + * Bootstrap Table of Contents v0.4.1 (http://afeld.github.io/bootstrap-toc/) + * Copyright 2015 Aidan Feldman + * Licensed under MIT (https://github.com/afeld/bootstrap-toc/blob/gh-pages/LICENSE.md) */ + +/* modified from https://github.com/twbs/bootstrap/blob/94b4076dd2efba9af71f0b18d4ee4b163aa9e0dd/docs/assets/css/src/docs.css#L548-L601 */ + +/* All levels of nav */ +nav[data-toggle='toc'] .nav > li > a { + display: block; + padding: 4px 20px; + font-size: 13px; + font-weight: 500; + color: #767676; +} +nav[data-toggle='toc'] .nav > li > a:hover, +nav[data-toggle='toc'] .nav > li > a:focus { + padding-left: 19px; + color: #563d7c; + text-decoration: none; + background-color: transparent; + border-left: 1px solid #563d7c; +} +nav[data-toggle='toc'] .nav > .active > a, +nav[data-toggle='toc'] .nav > .active:hover > a, +nav[data-toggle='toc'] .nav > .active:focus > a { + padding-left: 18px; + font-weight: bold; + color: #563d7c; + background-color: transparent; + border-left: 2px solid #563d7c; +} + +/* Nav: second level (shown on .active) */ +nav[data-toggle='toc'] .nav .nav { + display: none; /* Hide by default, but at >768px, show it */ + padding-bottom: 10px; +} +nav[data-toggle='toc'] .nav .nav > li > a { + padding-top: 1px; + padding-bottom: 1px; + padding-left: 30px; + font-size: 12px; + font-weight: normal; +} +nav[data-toggle='toc'] .nav .nav > li > a:hover, +nav[data-toggle='toc'] .nav .nav > li > a:focus { + padding-left: 29px; +} +nav[data-toggle='toc'] .nav .nav > .active > a, +nav[data-toggle='toc'] .nav .nav > .active:hover > a, +nav[data-toggle='toc'] .nav .nav > .active:focus > a { + padding-left: 28px; + font-weight: 500; +} + +/* from https://github.com/twbs/bootstrap/blob/e38f066d8c203c3e032da0ff23cd2d6098ee2dd6/docs/assets/css/src/docs.css#L631-L634 */ +nav[data-toggle='toc'] .nav > .active > ul { + display: block; +} diff --git a/docs/bootstrap-toc.js b/docs/bootstrap-toc.js new file mode 100644 index 0000000..1cdd573 --- /dev/null +++ b/docs/bootstrap-toc.js @@ -0,0 +1,159 @@ +/*! + * Bootstrap Table of Contents v0.4.1 (http://afeld.github.io/bootstrap-toc/) + * Copyright 2015 Aidan Feldman + * Licensed under MIT (https://github.com/afeld/bootstrap-toc/blob/gh-pages/LICENSE.md) */ +(function() { + 'use strict'; + + window.Toc = { + helpers: { + // return all matching elements in the set, or their descendants + findOrFilter: function($el, selector) { + // http://danielnouri.org/notes/2011/03/14/a-jquery-find-that-also-finds-the-root-element/ + // http://stackoverflow.com/a/12731439/358804 + var $descendants = $el.find(selector); + return $el.filter(selector).add($descendants).filter(':not([data-toc-skip])'); + }, + + generateUniqueIdBase: function(el) { + var text = $(el).text(); + var anchor = text.trim().toLowerCase().replace(/[^A-Za-z0-9]+/g, '-'); + return anchor || el.tagName.toLowerCase(); + }, + + generateUniqueId: function(el) { + var anchorBase = this.generateUniqueIdBase(el); + for (var i = 0; ; i++) { + var anchor = anchorBase; + if (i > 0) { + // add suffix + anchor += '-' + i; + } + // check if ID already exists + if (!document.getElementById(anchor)) { + return anchor; + } + } + }, + + generateAnchor: function(el) { + if (el.id) { + return el.id; + } else { + var anchor = this.generateUniqueId(el); + el.id = anchor; + return anchor; + } + }, + + createNavList: function() { + return $('
    '); + }, + + createChildNavList: function($parent) { + var $childList = this.createNavList(); + $parent.append($childList); + return $childList; + }, + + generateNavEl: function(anchor, text) { + var $a = $(''); + $a.attr('href', '#' + anchor); + $a.text(text); + var $li = $('
  • '); + $li.append($a); + return $li; + }, + + generateNavItem: function(headingEl) { + var anchor = this.generateAnchor(headingEl); + var $heading = $(headingEl); + var text = $heading.data('toc-text') || $heading.text(); + return this.generateNavEl(anchor, text); + }, + + // Find the first heading level (`

    `, then `

    `, etc.) that has more than one element. Defaults to 1 (for `

    `). + getTopLevel: function($scope) { + for (var i = 1; i <= 6; i++) { + var $headings = this.findOrFilter($scope, 'h' + i); + if ($headings.length > 1) { + return i; + } + } + + return 1; + }, + + // returns the elements for the top level, and the next below it + getHeadings: function($scope, topLevel) { + var topSelector = 'h' + topLevel; + + var secondaryLevel = topLevel + 1; + var secondarySelector = 'h' + secondaryLevel; + + return this.findOrFilter($scope, topSelector + ',' + secondarySelector); + }, + + getNavLevel: function(el) { + return parseInt(el.tagName.charAt(1), 10); + }, + + populateNav: function($topContext, topLevel, $headings) { + var $context = $topContext; + var $prevNav; + + var helpers = this; + $headings.each(function(i, el) { + var $newNav = helpers.generateNavItem(el); + var navLevel = helpers.getNavLevel(el); + + // determine the proper $context + if (navLevel === topLevel) { + // use top level + $context = $topContext; + } else if ($prevNav && $context === $topContext) { + // create a new level of the tree and switch to it + $context = helpers.createChildNavList($prevNav); + } // else use the current $context + + $context.append($newNav); + + $prevNav = $newNav; + }); + }, + + parseOps: function(arg) { + var opts; + if (arg.jquery) { + opts = { + $nav: arg + }; + } else { + opts = arg; + } + opts.$scope = opts.$scope || $(document.body); + return opts; + } + }, + + // accepts a jQuery object, or an options object + init: function(opts) { + opts = this.helpers.parseOps(opts); + + // ensure that the data attribute is in place for styling + opts.$nav.attr('data-toggle', 'toc'); + + var $topContext = this.helpers.createChildNavList(opts.$nav); + var topLevel = this.helpers.getTopLevel(opts.$scope); + var $headings = this.helpers.getHeadings(opts.$scope, topLevel); + this.helpers.populateNav($topContext, topLevel, $headings); + } + }; + + $(function() { + $('nav[data-toggle="toc"]').each(function(i, el) { + var $nav = $(el); + Toc.init($nav); + }); + }); +})(); diff --git a/docs/docsearch.css b/docs/docsearch.css new file mode 100644 index 0000000..e5f1fe1 --- /dev/null +++ b/docs/docsearch.css @@ -0,0 +1,148 @@ +/* Docsearch -------------------------------------------------------------- */ +/* + Source: https://github.com/algolia/docsearch/ + License: MIT +*/ + +.algolia-autocomplete { + display: block; + -webkit-box-flex: 1; + -ms-flex: 1; + flex: 1 +} + +.algolia-autocomplete .ds-dropdown-menu { + width: 100%; + min-width: none; + max-width: none; + padding: .75rem 0; + background-color: #fff; + background-clip: padding-box; + border: 1px solid rgba(0, 0, 0, .1); + box-shadow: 0 .5rem 1rem rgba(0, 0, 0, .175); +} + +@media (min-width:768px) { + .algolia-autocomplete .ds-dropdown-menu { + width: 175% + } +} + +.algolia-autocomplete .ds-dropdown-menu::before { + display: none +} + +.algolia-autocomplete .ds-dropdown-menu [class^=ds-dataset-] { + padding: 0; + background-color: rgb(255,255,255); + border: 0; + max-height: 80vh; +} + +.algolia-autocomplete .ds-dropdown-menu .ds-suggestions { + margin-top: 0 +} + +.algolia-autocomplete .algolia-docsearch-suggestion { + padding: 0; + overflow: visible +} + +.algolia-autocomplete .algolia-docsearch-suggestion--category-header { + padding: .125rem 1rem; + margin-top: 0; + font-size: 1.3em; + font-weight: 500; + color: #00008B; + border-bottom: 0 +} + +.algolia-autocomplete .algolia-docsearch-suggestion--wrapper { + float: none; + padding-top: 0 +} + +.algolia-autocomplete .algolia-docsearch-suggestion--subcategory-column { + float: none; + width: auto; + padding: 0; + text-align: left +} + +.algolia-autocomplete .algolia-docsearch-suggestion--content { + float: none; + width: auto; + padding: 0 +} + +.algolia-autocomplete .algolia-docsearch-suggestion--content::before { + display: none +} + +.algolia-autocomplete .ds-suggestion:not(:first-child) .algolia-docsearch-suggestion--category-header { + padding-top: .75rem; + margin-top: .75rem; + border-top: 1px solid rgba(0, 0, 0, .1) +} + +.algolia-autocomplete .ds-suggestion .algolia-docsearch-suggestion--subcategory-column { + display: block; + padding: .1rem 1rem; + margin-bottom: 0.1; + font-size: 1.0em; + font-weight: 400 + /* display: none */ +} + +.algolia-autocomplete .algolia-docsearch-suggestion--title { + display: block; + padding: .25rem 1rem; + margin-bottom: 0; + font-size: 0.9em; + font-weight: 400 +} + +.algolia-autocomplete .algolia-docsearch-suggestion--text { + padding: 0 1rem .5rem; + margin-top: -.25rem; + font-size: 0.8em; + font-weight: 400; + line-height: 1.25 +} + +.algolia-autocomplete .algolia-docsearch-footer { + width: 110px; + height: 20px; + z-index: 3; + margin-top: 10.66667px; + float: right; + font-size: 0; + line-height: 0; +} + +.algolia-autocomplete .algolia-docsearch-footer--logo { + background-image: url("data:image/svg+xml;utf8,"); + background-repeat: no-repeat; + background-position: 50%; + background-size: 100%; + overflow: hidden; + text-indent: -9000px; + width: 100%; + height: 100%; + display: block; + transform: translate(-8px); +} + +.algolia-autocomplete .algolia-docsearch-suggestion--highlight { + color: #FF8C00; + background: rgba(232, 189, 54, 0.1) +} + + +.algolia-autocomplete .algolia-docsearch-suggestion--text .algolia-docsearch-suggestion--highlight { + box-shadow: inset 0 -2px 0 0 rgba(105, 105, 105, .5) +} + +.algolia-autocomplete .ds-suggestion.ds-cursor .algolia-docsearch-suggestion--content { + background-color: rgba(192, 192, 192, .15) +} diff --git a/docs/docsearch.js b/docs/docsearch.js new file mode 100644 index 0000000..b35504c --- /dev/null +++ b/docs/docsearch.js @@ -0,0 +1,85 @@ +$(function() { + + // register a handler to move the focus to the search bar + // upon pressing shift + "/" (i.e. "?") + $(document).on('keydown', function(e) { + if (e.shiftKey && e.keyCode == 191) { + e.preventDefault(); + $("#search-input").focus(); + } + }); + + $(document).ready(function() { + // do keyword highlighting + /* modified from https://jsfiddle.net/julmot/bL6bb5oo/ */ + var mark = function() { + + var referrer = document.URL ; + var paramKey = "q" ; + + if (referrer.indexOf("?") !== -1) { + var qs = referrer.substr(referrer.indexOf('?') + 1); + var qs_noanchor = qs.split('#')[0]; + var qsa = qs_noanchor.split('&'); + var keyword = ""; + + for (var i = 0; i < qsa.length; i++) { + var currentParam = qsa[i].split('='); + + if (currentParam.length !== 2) { + continue; + } + + if (currentParam[0] == paramKey) { + keyword = decodeURIComponent(currentParam[1].replace(/\+/g, "%20")); + } + } + + if (keyword !== "") { + $(".contents").unmark({ + done: function() { + $(".contents").mark(keyword); + } + }); + } + } + }; + + mark(); + }); +}); + +/* Search term highlighting ------------------------------*/ + +function matchedWords(hit) { + var words = []; + + var hierarchy = hit._highlightResult.hierarchy; + // loop to fetch from lvl0, lvl1, etc. + for (var idx in hierarchy) { + words = words.concat(hierarchy[idx].matchedWords); + } + + var content = hit._highlightResult.content; + if (content) { + words = words.concat(content.matchedWords); + } + + // return unique words + var words_uniq = [...new Set(words)]; + return words_uniq; +} + +function updateHitURL(hit) { + + var words = matchedWords(hit); + var url = ""; + + if (hit.anchor) { + url = hit.url_without_anchor + '?q=' + escape(words.join(" ")) + '#' + hit.anchor; + } else { + url = hit.url + '?q=' + escape(words.join(" ")); + } + + return url; +} diff --git a/docs/index.html b/docs/index.html new file mode 100644 index 0000000..a61008f --- /dev/null +++ b/docs/index.html @@ -0,0 +1,146 @@ + + + + + + + +Charts for Monitoring Clinical Trial Safety • safetyCharts + + + + + + + + + + +
    +
    + + + + +
    +
    + +
    +

    +safetyCharts

    + + +

    The {safetyCharts} R package contains a set of charts used in clinical trial research. These charts are optimized for usage with the {safetyGraphics} package and shiny application, but can also easily be used as standalone displays.

    +
    +
    +

    +Chart Types

    +

    There are several types of charts included in this package:

    +
      +
    • Static Displays - These are written as R functions that output static statistical displays. See the help files for each chart for more details. Saved in \R.
      • +
    • +htmlwidgets - Interactive graphics written in javascript and configured for R using the htmlwidgets package. Saved in \inst\htmlwidgets.
      • +
    • Chart configuration Files - YAML files specifying chart details needed for safetyGraphics. Saved in \inst\config.
      • +
    +

    For more information on using these charts with {safetyGraphics} see this vignette.

    +
    + +
    + + +
    + + +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + diff --git a/docs/link.svg b/docs/link.svg new file mode 100644 index 0000000..88ad827 --- /dev/null +++ b/docs/link.svg @@ -0,0 +1,12 @@ + + + + + + diff --git a/docs/news/index.html b/docs/news/index.html new file mode 100644 index 0000000..cf675c7 --- /dev/null +++ b/docs/news/index.html @@ -0,0 +1,163 @@ + + + + + + + + +Changelog • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Changelog

    + Source: NEWS.md +
    + +
    +

    +safetyCharts v0.3 Unreleased +

    +

    This release adds several new features and bug fixes. New features include:

    +
      +
    • Chart metadata has been migrated from safetygraphics to safetycharts to support the new metadata framework being introduced in the upcoming safetyGraphics v2.1 release.
      • +
    • A new hepExplorer() function has been added to allow for a simple workflow to render the hepatic explorer with customizations. hepExplorer() calls a new renderWidget() function has been added for a more generalized widget rendering workflow. More updates may be added in this area in future releases.
      • +
    +
    +
    +

    +safetyCharts v0.2 Unreleased +

    +

    Initial CRAN release for safetyCharts.

    +

    See the GitHub release tracker for additional release documentation and links to issues.

    +
    +
    + + + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/pkgdown.css b/docs/pkgdown.css new file mode 100644 index 0000000..1273238 --- /dev/null +++ b/docs/pkgdown.css @@ -0,0 +1,367 @@ +/* Sticky footer */ + +/** + * Basic idea: https://philipwalton.github.io/solved-by-flexbox/demos/sticky-footer/ + * Details: https://github.com/philipwalton/solved-by-flexbox/blob/master/assets/css/components/site.css + * + * .Site -> body > .container + * .Site-content -> body > .container .row + * .footer -> footer + * + * Key idea seems to be to ensure that .container and __all its parents__ + * have height set to 100% + * + */ + +html, body { + height: 100%; +} + +body { + position: relative; +} + +body > .container { + display: flex; + height: 100%; + flex-direction: column; +} + +body > .container .row { + flex: 1 0 auto; +} + +footer { + margin-top: 45px; + padding: 35px 0 36px; + border-top: 1px solid #e5e5e5; + color: #666; + display: flex; + flex-shrink: 0; +} +footer p { + margin-bottom: 0; +} +footer div { + flex: 1; +} +footer .pkgdown { + text-align: right; +} +footer p { + margin-bottom: 0; +} + +img.icon { + float: right; +} + +img { + max-width: 100%; +} + +/* Fix bug in bootstrap (only seen in firefox) */ +summary { + display: list-item; +} + +/* Typographic tweaking ---------------------------------*/ + +.contents .page-header { + margin-top: calc(-60px + 1em); +} + +dd { + margin-left: 3em; +} + +/* Section anchors ---------------------------------*/ + +a.anchor { + margin-left: -30px; + display:inline-block; + width: 30px; + height: 30px; + visibility: hidden; + + background-image: url(./link.svg); + background-repeat: no-repeat; + background-size: 20px 20px; + background-position: center center; +} + +.hasAnchor:hover a.anchor { + visibility: visible; +} + +@media (max-width: 767px) { + .hasAnchor:hover a.anchor { + visibility: hidden; + } +} + + +/* Fixes for fixed navbar --------------------------*/ + +.contents h1, .contents h2, .contents h3, .contents h4 { + padding-top: 60px; + margin-top: -40px; +} + +/* Navbar submenu --------------------------*/ + +.dropdown-submenu { + position: relative; +} + +.dropdown-submenu>.dropdown-menu { + top: 0; + left: 100%; + margin-top: -6px; + margin-left: -1px; + border-radius: 0 6px 6px 6px; +} + +.dropdown-submenu:hover>.dropdown-menu { + display: block; +} + +.dropdown-submenu>a:after { + display: block; + content: " "; + float: right; + width: 0; + height: 0; + border-color: transparent; + border-style: solid; + border-width: 5px 0 5px 5px; + border-left-color: #cccccc; + margin-top: 5px; + margin-right: -10px; +} + +.dropdown-submenu:hover>a:after { + border-left-color: #ffffff; +} + +.dropdown-submenu.pull-left { + float: none; +} + +.dropdown-submenu.pull-left>.dropdown-menu { + left: -100%; + margin-left: 10px; + border-radius: 6px 0 6px 6px; +} + +/* Sidebar --------------------------*/ + +#pkgdown-sidebar { + margin-top: 30px; + position: -webkit-sticky; + position: sticky; + top: 70px; +} + +#pkgdown-sidebar h2 { + font-size: 1.5em; + margin-top: 1em; +} + +#pkgdown-sidebar h2:first-child { + margin-top: 0; +} + +#pkgdown-sidebar .list-unstyled li { + margin-bottom: 0.5em; +} + +/* bootstrap-toc tweaks ------------------------------------------------------*/ + +/* All levels of nav */ + +nav[data-toggle='toc'] .nav > li > a { + padding: 4px 20px 4px 6px; + font-size: 1.5rem; + font-weight: 400; + color: inherit; +} + +nav[data-toggle='toc'] .nav > li > a:hover, +nav[data-toggle='toc'] .nav > li > a:focus { + padding-left: 5px; + color: inherit; + border-left: 1px solid #878787; +} + +nav[data-toggle='toc'] .nav > .active > a, +nav[data-toggle='toc'] .nav > .active:hover > a, +nav[data-toggle='toc'] .nav > .active:focus > a { + padding-left: 5px; + font-size: 1.5rem; + font-weight: 400; + color: inherit; + border-left: 2px solid #878787; +} + +/* Nav: second level (shown on .active) */ + +nav[data-toggle='toc'] .nav .nav { + display: none; /* Hide by default, but at >768px, show it */ + padding-bottom: 10px; +} + +nav[data-toggle='toc'] .nav .nav > li > a { + padding-left: 16px; + font-size: 1.35rem; +} + +nav[data-toggle='toc'] .nav .nav > li > a:hover, +nav[data-toggle='toc'] .nav .nav > li > a:focus { + padding-left: 15px; +} + +nav[data-toggle='toc'] .nav .nav > .active > a, +nav[data-toggle='toc'] .nav .nav > .active:hover > a, +nav[data-toggle='toc'] .nav .nav > .active:focus > a { + padding-left: 15px; + font-weight: 500; + font-size: 1.35rem; +} + +/* orcid ------------------------------------------------------------------- */ + +.orcid { + font-size: 16px; + color: #A6CE39; + /* margins are required by official ORCID trademark and display guidelines */ + margin-left:4px; + margin-right:4px; + vertical-align: middle; +} + +/* Reference index & topics ----------------------------------------------- */ + +.ref-index th {font-weight: normal;} + +.ref-index td {vertical-align: top; min-width: 100px} +.ref-index .icon {width: 40px;} +.ref-index .alias {width: 40%;} +.ref-index-icons .alias {width: calc(40% - 40px);} +.ref-index .title {width: 60%;} + +.ref-arguments th {text-align: right; padding-right: 10px;} +.ref-arguments th, .ref-arguments td {vertical-align: top; min-width: 100px} +.ref-arguments .name {width: 20%;} +.ref-arguments .desc {width: 80%;} + +/* Nice scrolling for wide elements --------------------------------------- */ + +table { + display: block; + overflow: auto; +} + +/* Syntax highlighting ---------------------------------------------------- */ + +pre { + word-wrap: normal; + word-break: normal; + border: 1px solid #eee; +} + +pre, code { + background-color: #f8f8f8; + color: #333; +} + +pre code { + overflow: auto; + word-wrap: normal; + white-space: pre; +} + +pre .img { + margin: 5px 0; +} + +pre .img img { + background-color: #fff; + display: block; + height: auto; +} + +code a, pre a { + color: #375f84; +} + +a.sourceLine:hover { + text-decoration: none; +} + +.fl {color: #1514b5;} +.fu {color: #000000;} /* function */ +.ch,.st {color: #036a07;} /* string */ +.kw {color: #264D66;} /* keyword */ +.co {color: #888888;} /* comment */ + +.message { color: black; font-weight: bolder;} +.error { color: orange; font-weight: bolder;} +.warning { color: #6A0366; font-weight: bolder;} + +/* Clipboard --------------------------*/ + +.hasCopyButton { + position: relative; +} + +.btn-copy-ex { + position: absolute; + right: 0; + top: 0; + visibility: hidden; +} + +.hasCopyButton:hover button.btn-copy-ex { + visibility: visible; +} + +/* headroom.js ------------------------ */ + +.headroom { + will-change: transform; + transition: transform 200ms linear; +} +.headroom--pinned { + transform: translateY(0%); +} +.headroom--unpinned { + transform: translateY(-100%); +} + +/* mark.js ----------------------------*/ + +mark { + background-color: rgba(255, 255, 51, 0.5); + border-bottom: 2px solid rgba(255, 153, 51, 0.3); + padding: 1px; +} + +/* vertical spacing after htmlwidgets */ +.html-widget { + margin-bottom: 10px; +} + +/* fontawesome ------------------------ */ + +.fab { + font-family: "Font Awesome 5 Brands" !important; +} + +/* don't display links in code chunks when printing */ +/* source: https://stackoverflow.com/a/10781533 */ +@media print { + code a:link:after, code a:visited:after { + content: ""; + } +} diff --git a/docs/pkgdown.js b/docs/pkgdown.js new file mode 100644 index 0000000..7e7048f --- /dev/null +++ b/docs/pkgdown.js @@ -0,0 +1,108 @@ +/* http://gregfranko.com/blog/jquery-best-practices/ */ +(function($) { + $(function() { + + $('.navbar-fixed-top').headroom(); + + $('body').css('padding-top', $('.navbar').height() + 10); + $(window).resize(function(){ + $('body').css('padding-top', $('.navbar').height() + 10); + }); + + $('[data-toggle="tooltip"]').tooltip(); + + var cur_path = paths(location.pathname); + var links = $("#navbar ul li a"); + var max_length = -1; + var pos = -1; + for (var i = 0; i < links.length; i++) { + if (links[i].getAttribute("href") === "#") + continue; + // Ignore external links + if (links[i].host !== location.host) + continue; + + var nav_path = paths(links[i].pathname); + + var length = prefix_length(nav_path, cur_path); + if (length > max_length) { + max_length = length; + pos = i; + } + } + + // Add class to parent
  • , and enclosing
  • if in dropdown + if (pos >= 0) { + var menu_anchor = $(links[pos]); + menu_anchor.parent().addClass("active"); + menu_anchor.closest("li.dropdown").addClass("active"); + } + }); + + function paths(pathname) { + var pieces = pathname.split("/"); + pieces.shift(); // always starts with / + + var end = pieces[pieces.length - 1]; + if (end === "index.html" || end === "") + pieces.pop(); + return(pieces); + } + + // Returns -1 if not found + function prefix_length(needle, haystack) { + if (needle.length > haystack.length) + return(-1); + + // Special case for length-0 haystack, since for loop won't run + if (haystack.length === 0) { + return(needle.length === 0 ? 0 : -1); + } + + for (var i = 0; i < haystack.length; i++) { + if (needle[i] != haystack[i]) + return(i); + } + + return(haystack.length); + } + + /* Clipboard --------------------------*/ + + function changeTooltipMessage(element, msg) { + var tooltipOriginalTitle=element.getAttribute('data-original-title'); + element.setAttribute('data-original-title', msg); + $(element).tooltip('show'); + element.setAttribute('data-original-title', tooltipOriginalTitle); + } + + if(ClipboardJS.isSupported()) { + $(document).ready(function() { + var copyButton = ""; + + $(".examples, div.sourceCode").addClass("hasCopyButton"); + + // Insert copy buttons: + $(copyButton).prependTo(".hasCopyButton"); + + // Initialize tooltips: + $('.btn-copy-ex').tooltip({container: 'body'}); + + // Initialize clipboard: + var clipboardBtnCopies = new ClipboardJS('[data-clipboard-copy]', { + text: function(trigger) { + return trigger.parentNode.textContent; + } + }); + + clipboardBtnCopies.on('success', function(e) { + changeTooltipMessage(e.trigger, 'Copied!'); + e.clearSelection(); + }); + + clipboardBtnCopies.on('error', function() { + changeTooltipMessage(e.trigger,'Press Ctrl+C or Command+C to copy'); + }); + }); + } +})(window.jQuery || window.$) diff --git a/docs/pkgdown.yml b/docs/pkgdown.yml new file mode 100644 index 0000000..13b47be --- /dev/null +++ b/docs/pkgdown.yml @@ -0,0 +1,6 @@ +pandoc: 2.11.4 +pkgdown: 1.6.1 +pkgdown_sha: ~ +articles: {} +last_built: 2022-03-24T17:14Z + diff --git a/docs/reference/QT_OutlierExplorer_server.html b/docs/reference/QT_OutlierExplorer_server.html new file mode 100644 index 0000000..14e7255 --- /dev/null +++ b/docs/reference/QT_OutlierExplorer_server.html @@ -0,0 +1,177 @@ + + + + + + + + +QT Outlier Explorer Module - UI — QT_OutlierExplorer_server • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    QT Outlier Explorer Module - UI

    + Source: R/mod_QT_OutlierExplorer.R + +
    + +
    +

    QT Outlier Explorer Module - UI

    +
    + + 
    QT_OutlierExplorer_server(input, output, session, params)
    + +

    Arguments

    + + + + + + + + + + + + + + + + + + +
    input

    module input

    output

    module output

    session

    module session

    params

    parameters object with data and settings options.

    + +

    Value

    + +

    returns shiny module Server function

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/QT_OutlierExplorer_ui.html b/docs/reference/QT_OutlierExplorer_ui.html new file mode 100644 index 0000000..371e2a0 --- /dev/null +++ b/docs/reference/QT_OutlierExplorer_ui.html @@ -0,0 +1,165 @@ + + + + + + + + +QT Outlier Explorer Module - UI — QT_OutlierExplorer_ui • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    QT Outlier Explorer Module - UI

    + Source: R/mod_QT_OutlierExplorer.R + +
    + +
    +

    QT Outlier Explorer Module - UI

    +
    + + 
    QT_OutlierExplorer_ui(id)
    + +

    Arguments

    + + + + + + +
    id

    module id

    + +

    Value

    + +

    returns shiny module UI

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/QT_Outlier_Explorer.html b/docs/reference/QT_Outlier_Explorer.html new file mode 100644 index 0000000..394e088 --- /dev/null +++ b/docs/reference/QT_Outlier_Explorer.html @@ -0,0 +1,183 @@ + + + + + + + + +QT Outlier Explorer — QT_Outlier_Explorer • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    QT Outlier Explorer

    + Source: R/QT_Outlier_Explorer.R + +
    + +
    +

    QT Outlier Explorer

    +
    + + 
    QT_Outlier_Explorer(data, settings)
    + +

    Arguments

    + + + + + + + + + + +
    data

    ECG data structured as one record per person per visit per measurement. See details for column requirements.

    settings

    named list of settings with the parameters specified below.

    + +

    Value

    + +

    returns a chart object

    +

    Details

    + +

    The settings object provides details the columns in the data set.

    +
      +

    • "id_col"ID column

      • +

    • "value_col"Value column

      • +

    • "measure_col"Measure column

      • +

    • "measure_values"Measure values

      • +

    • "visit_col"Visit column

      • +

    • "visitn_col"Visit number column (numeric)

      • +

    • "baseline_flag_colBaseline flag column

      • +

    • "baseline_flag_valuesBaseline flag value

      • +
    + + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/Rplot001.png b/docs/reference/Rplot001.png new file mode 100644 index 0000000000000000000000000000000000000000..94d42e6b81f2a259ebf279e519e30b1a7315f12d GIT binary patch literal 34966 zcmbrm2RzpQ+cr+gD4Xm}Mj@MI6e4>?$SylGB)iBCN%jaKdq?(`O*Yv|_TK9`KYf4C zb3ga%x&QZl|DUHs19}W%<=B3n2#wetGt<9<>iXlWLF|rcOJLZneoPj$-OuUwZ zm=v-KQsj^91cOdU@b5Fyb&RKsE!nslWLFM9Ihfix@i7=0Rhd-LIM`qNb>^BR@_sqH z_fBR{-pRL#J2He4nD_()s&x^0`6vVg{dUc03Q|(fP?-%G7#OaN=H=hJ*>6r9m!YkP z120re+KfIIXquP1yhWe8l3#^O>v@o!7ExNt=Exwd(GG@tv#BqVW!v?!I8 zl{0&;vvxuXfwb?W3Buam$H!aAxucj{SxKs@5|e;NURhD6AMr8{C5bPWpXvvMqe{&!0c{JUwgK%xF>YasBCiy+>B~Z`9_m z!0TL2$;6mw$VVnw-b&CD6BEb4frRhgg|l9(noNi!4wU+oZ7F^7`LX`1D?}_x&E#eY z?^VYt^XFSg4HS;bQRBUD$jZ4b-t_fm@61?>L}i+f*YF$LI!VL+I=fJjha1B4Oj~LH zt+rp|OTM2Ih9zSPS(LPmu$aXtL|g;}@2|vo2L=SN*Z=S9&V@=uK%ni76%!Ef{gOhx zl#~>S;U(sO_Yw2aASs3b=`=ELs~>$_$fujsJUm1nX}ry__>z-TQYp-bjgy7O?(3bM zt@-%r=m6ilvwN50Qdz@I$Zy=Z!OF?$*ZE6=kD{znhg_CQs&9t(Ght!=in+OYVI@UV 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zgOQHI-Y&8G`!H2Y1_8-$eiA$$S6f?4HQ5gqnJ9b4YnB8Y0shPiGYV1jug2E%(OU8W_G@JcOqi|KM>EZE|4mQsK7Tz@OI=Oea{9LN>LI5rGmG7F}cUEgeE`F%gEvw9{%I?R|BV-9CvP(?8mR^CInP!ZO=p$E!F_3L@`e8>Z>>dn$ zBsNFL>Pq1rn|Qo_gkdCo?TpD4nfNP3*Zyis98cqv`Pf4x^aC#;I)FeFBIRP9pZ7=m zh6^Sg;TaJ?NO*X-t-U?bDL{(&Q9-{JmBu^PZbEqB7HKR}@y32jp@X`n@w}Pkkx^QeCrQu6@)mV_3yRsuV zJH#OaaYwwOA?OKa6)6|d)qv&Ge|EO+$}+-RgD$%GX@8 zV(<*lB-(tEQzCoYYS+Q?-dR<}+v_X}$ZhxIj;gFmSpJ)-O6A5erG`I6oT@)?nXJd@ zlck=Dj1CU-bm1tcwbg@H;`KJmzE?n=oUvDtS;cf%Jiv?@dxrfY9%Rq4znjZl358P3)D-$@AD=rj6)ZL7yPx%@ zD|qs3wnExfSPs|{1rAYHfgI}tb(vPr4=baSNbAkMMGC96Hd^;lmCih+=T+a z>Xu=CH`nT=#p(&C%WScr=A_+L4c{t_4uA36o>{Z#S=r<_@1OE082eJ*s9f~6lY3^P zZ91ZDeJ1o&uVzKll16E1X)#W8DQ9~n%tTEq1!_s<$$YGos+$jZ<6M1UEGY5a4oilD zCH#gBgl{EjDChEE%cGywb41k-^sH?%_7*N5A5jVpJ#V#sNOfA1ZZSwM_i%Vulg+UZ zgl;Yi>~pS>Y^%F6NT&pxToU-jxQXC0(J?!<6S;+h^gx?qmu2F+-9mHBdgz&D(cXS~ z9QD=#dj8~GpMQuZ-9EY?qbY@|y_ZRQ*Kuc)z>nt9=;^6Rr}+C1Y`dE`LkJDCEi4(v zT3a?Zz9v0xe1uP@W<)vFaC6z-y7G + + + + + + + +Demographics Table RTF - UI — demogRTF_server • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Demographics Table RTF - UI

    + Source: R/mod_demogRTF.R + +
    + +
    +

    Demographics Table RTF - UI

    +
    + + 
    demogRTF_server(input, output, session, params)
    + +

    Arguments

    + + + + + + + + + + + + + + + + + + +
    input

    module input

    output

    module output

    session

    module session

    params

    parameters object with data and settings options.

    + +

    Value

    + +

    returns shiny module Server function

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/demogRTF_table.html b/docs/reference/demogRTF_table.html new file mode 100644 index 0000000..e0db4fc --- /dev/null +++ b/docs/reference/demogRTF_table.html @@ -0,0 +1,310 @@ + + + + + + + + +create demographics RTF table — demogRTF_table • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    create demographics RTF table

    + Source: R/mod_demogRTF.R + +
    + +
    +

    create demographics RTF table

    +
    + + 
    demogRTF_table(data, settings)
    + +

    Arguments

    + + + + + + + + + + +
    data

    demographics data frame with columns specified in settings object

    settings

    list with parameters specifying the column names for:

      +

    • sex (settings$sex_col),

      • +

    • race (settings$race_col)

      • +

    • age (settings$age_Col)

      • +
    + +

    Value

    + +

    rtf doc object

    + +

    Examples

    + 
    settings <- list(treatment_col = "ARM", sex_col = "SEX", race_col = "RACE", age_col = "AGE")
+demogRTF_table(safetyData::sdtm_dm, settings)
+
    #> Warning: number of items to replace is not a multiple of replacement length
    #> $table
+#>                                 Placebo\l   Xanomelin   Xanomelin    Screen    
+#>                                 ine(N=86)       e           e       Failure\l  
+#>                                               High         Low      ine(N=52)  
+#>                                             Dose\line   Dose\line              
+#>                                              (N=84)      (N=84)                
+#>  ──────────────────────────────────────────────────────────────────────────────
+#>    Race          AMERICAN       0 ( 0.0%)   1 ( 1.2%)   0 ( 0.0%)   1 ( 1.9%)  
+#>                  INDIAN OR                                                     
+#>                  ALASKA                                                        
+#>                  NATIVE                                                        
+#>    Race          ASIAN          0 ( 0.0%)   0 ( 0.0%)   0 ( 0.0%)   2 ( 3.8%)  
+#>    Race          BLACK OR       8 ( 9.3%)      9 (      6 ( 7.1%)      6 (     
+#>                  AFRICAN                     10.7%)                  11.5%)    
+#>                  AMERICAN                                                      
+#>    Race          WHITE            78 (        74 (        78 (        43 (     
+#>                                  90.7%)      88.1%)      92.9%)      82.7%)    
+#>    Age (Years)   n                 86          84          84          52      
+#>    Age (Years)   Mean (SD)       75.2 (      74.4 (      75.7 (      75.1 (    
+#>                                   8.59)       7.89)       8.29)       9.70)    
+#>    Age (Years)   Median           76.0        76.0        77.5        76.0     
+#>    Age (Years)   Q1, Q3           69.2,       70.8,       71.0,       71.8,    
+#>                                   81.8        80.0        82.0        81.2     
+#>    Age (Years)   Min, Max        52, 89      56, 88      51, 88      50, 89    
+#>    Age (Years)   Missing            0           0           0           0      
+#> 
+#> Column names: row_label1, row_label2, var1_Placebo, var1_Xanomeline High Dose,
+#> var1_Xanomeline Low Dose, var1_Screen Failure, var1_Total
+#> 
+#> 6/7 columns shown.
+#> $titles
+#> $titles[[1]]
+#> $text
+#> [1] "Protocol: XXX"              "PAGE_FORMAT: Page %s of %s"
+#> 
+#> attr(,"align")
+#> [1] "split"
+#> attr(,"bold")
+#> [1] TRUE
+#> attr(,"italic")
+#> [1] TRUE
+#> attr(,"font")
+#> [1] NA
+#> attr(,"font_size")
+#> [1] NA
+#> attr(,"index")
+#> [1] NA
+#> attr(,"class")
+#> [1] "hf_line"
+#> 
+#> $titles[[2]]
+#> $text
+#> [1] "Table 14-2.01"
+#> 
+#> attr(,"align")
+#> [1] "center"
+#> attr(,"bold")
+#> [1] TRUE
+#> attr(,"italic")
+#> [1] TRUE
+#> attr(,"font")
+#> [1] NA
+#> attr(,"font_size")
+#> [1] NA
+#> attr(,"index")
+#> [1] NA
+#> attr(,"class")
+#> [1] "hf_line"
+#> 
+#> $titles[[3]]
+#> $text
+#> [1] "Summary of Demographic and Baseline Characteristics"
+#> 
+#> attr(,"align")
+#> [1] "center"
+#> attr(,"bold")
+#> [1] TRUE
+#> attr(,"italic")
+#> [1] TRUE
+#> attr(,"font")
+#> [1] NA
+#> attr(,"font_size")
+#> [1] NA
+#> attr(,"index")
+#> [1] NA
+#> attr(,"class")
+#> [1] "hf_line"
+#> 
+#> 
+#> $footnotes
+#> $footnotes[[1]]
+#> $text
+#> [1] "FILE_PATH: Source: %s"            "DATE_FORMAT: %H:%M %A, %B %d, %Y"
+#> 
+#> attr(,"align")
+#> [1] "split"
+#> attr(,"bold")
+#> [1] FALSE
+#> attr(,"italic")
+#> [1] TRUE
+#> attr(,"font")
+#> [1] NA
+#> attr(,"font_size")
+#> [1] NA
+#> attr(,"index")
+#> [1] NA
+#> attr(,"class")
+#> [1] "hf_line"
+#> 
+#> 
+#> attr(,"margins")
+#>    top bottom   left  right 
+#>      1      1      1      1 
+#> attr(,"orientation")
+#> [1] "landscape"
+#> attr(,"header_height")
+#> [1] 0.5
+#> attr(,"footer_height")
+#> [1] 0.5
+#> attr(,"pagesize")
+#>  width height 
+#>   11.0    8.5 
+#> attr(,"font")
+#> [1] "Courier New"
+#> attr(,"font_size")
+#> [1] 10
+#> attr(,"ignore_cell_padding")
+#> [1] TRUE
+#> attr(,"column_header_buffer")
+#>    top bottom 
+#>      1      0 
+#> attr(,"class")
+#> [1] "rtf_doc"
    
+
    +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/demogRTF_ui.html b/docs/reference/demogRTF_ui.html new file mode 100644 index 0000000..8e009c5 --- /dev/null +++ b/docs/reference/demogRTF_ui.html @@ -0,0 +1,165 @@ + + + + + + + + +Demographics Table RTF - UI — demogRTF_ui • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Demographics Table RTF - UI

    + Source: R/mod_demogRTF.R + +
    + +
    +

    Demographics Table RTF - UI

    +
    + + 
    demogRTF_ui(id)
    + +

    Arguments

    + + + + + + +
    id

    module id

    + +

    Value

    + +

    returns shiny module UI

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/hepExplorer.html b/docs/reference/hepExplorer.html new file mode 100644 index 0000000..1baeeae --- /dev/null +++ b/docs/reference/hepExplorer.html @@ -0,0 +1,232 @@ + + + + + + + + +Make standalone hepExplorer html widget — hepExplorer • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Make standalone hepExplorer html widget

    + Source: R/hepExplorer.R + +
    + +
    +

    Convience mapping of render_widget for hepExplorer.

    +
    + + 
    hepExplorer(df = safetyData::adam_adlbc, mapping = NULL, ...)
    + +

    Arguments

    + + + + + + + + + + + + + + +
    df

    data frame containing lab data used to render for hepExplorer. Default is safetyData::adam_adlbc.

    mapping

    named list with the current data mappings. See details for default mapping.

    ...

    additional options to be added to mapping. Will overwrite mapping.

    + +

    Details

    + +

    The data and mapping should match the specs described in the hepExplorer javascript library. Items passed in ... are added to mapping, and then the list is converted to json via jsonlite::toJSON(mapping, auto_unbox=TRUE, null="null").

    +

    The default mapping shown below is designed to work with data in the CDISC ADaM format (like safetydata::adam_adlbc).

    mapping <- list(
+           measure_col = "PARAM", 
+           measure_values = list(
+               ALT = "Alanine Aminotransferase (U/L)", 
+               AST = "Aspartate Aminotransferase (U/L)", 
+               TB = "Bilirubin (umol/L)",
+               ALP = "Alkaline Phosphatase (U/L)"
+           ), 
+           id_col = "USUBJID", 
+           value_col = "AVAL", 
+           normal_col_low = "A1LO",                    
+           normal_col_high = "A1HI", 
+           studyday_col = "ADY", 
+           visit_col = "VISIT",
+           visitn_col = "VISITNUM"
+       )                  
+
    + +

    Parameters that are not included in the default mapping can be accessed via ...; Key options and defaults for safetyData::adam_adlbc shown below:

      +

    • filters: list of columns to be included as data filters (e.g. `filters=c("SEX","AGEGR1")``)

      • +

    • group_cols: list of columns used to define grouping and set point color (e.g. `filters=c("SEX","AGEGR1")``)

      • +

    • x_options and y_options - specify which labs can be used for x and y axis dropdowns. By default, all options are included on x-axis, but only Bilirubin is shown on y-axis. To allow an interactive y-axis, use y_options="all".

      • +

    • baseline - flag defining the baseline visit for each participant. baseline must be provided to enable the mDish view on the hep-explorer chart. Define as a list with value_col and values (e.g. baseline=list(value_col="ABLFL",values="Y"))

      • +

    • title and warningText - Strings used to define the header text shown above the filters.

      • +
    + +

    For more options see the full specs in the javascript library.

    + +

    Examples

    + 
    if (FALSE) {
+# Render widget with defaults
+hepExplorer() 
+
+# Add age group to default
+hepExplorer(group_cols=c("SEX","AGEGR1")) 
+
+# Enable interactive y-axis
+hepExplorer(y_options='all') 
+
+# Use custom mapping for SDTM data
+hepExplorer(
+    df=safetyData::sdtm_lb,
+    measure_col = "LBTEST", 
+    measure_values = list(
+        ALT = "Alanine Aminotransferase", 
+        AST = "Aspartate Aminotransferase", 
+        TB = "Bilirubin",
+        ALP = "Alkaline Phosphatase"
+    ), 
+    id_col = "USUBJID", 
+    value_col = "LBSTRESN", 
+    normal_col_low = "LBORNRLO",                    
+    normal_col_high = "LBORNRHI", 
+    studyday_col = "LBDY", 
+    visit_col = "VISIT",
+    visitn_col = "VISITNUM"
+)
+}
+
+
    +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/index.html b/docs/reference/index.html new file mode 100644 index 0000000..a3094d7 --- /dev/null +++ b/docs/reference/index.html @@ -0,0 +1,323 @@ + + + + + + + + +Function reference • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Reference

    +
    + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +

    All functions

    +

    +
    +

    QT_OutlierExplorer_server()

    +

    QT Outlier Explorer Module - UI

    +

    QT_OutlierExplorer_ui()

    +

    QT Outlier Explorer Module - UI

    +

    QT_Outlier_Explorer()

    +

    QT Outlier Explorer

    +

    demogRTF_server()

    +

    Demographics Table RTF - UI

    +

    demogRTF_table()

    +

    create demographics RTF table

    +

    demogRTF_ui()

    +

    Demographics Table RTF - UI

    +

    hepExplorer()

    +

    Make standalone hepExplorer html widget

    +

    init_aeExplorer()

    +

    Initialize Settings for Adverse Event Explorer widget

    +

    init_aeTimelines()

    +

    Initialize Settings for AE Timeline widget

    +

    init_paneledOutlierExplorer()

    +

    Initialize Settings for Paneled Outlier Explorer widget

    +

    init_safetyOutlierExplorer()

    +

    Initialize Settings for Safety Outlier Explorer widget

    +

    init_safetyResultsOverTime()

    +

    Initialize Settings for Safety Results Over Time widget

    +

    init_safetyShiftPlot()

    +

    Initialize Settings for Safety Shift Plot widget

    +

    lab_distribution_server()

    +

    lab distribution Module - Server

    +

    lab_distribution_ui()

    +

    Lab distribution Module - UI

    +

    meta_aes

    +

    Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the ae domain. One record per unique data mapping

    +

    meta_dm

    +

    Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the dm domain. One record per unique data mapping

    +

    meta_ecg

    +

    Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the ecg domain. One record per unique data mapping

    +

    meta_hepExplorer

    +

    Metadata data frame containing information about the data mapping used to configure safetyGraphics for the hepExplorer Chart. One record per unique data mapping

    +

    meta_labs

    +

    Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the labs domain. One record per unique data mapping

    +

    render_widget()

    +

    Render an htmlwidget using standard safetyGraphics workflow

    +

    safetyOutlierExplorer_server()

    +

    Safety Outlier Explorer Module - UI

    +

    safetyOutlierExplorer_ui()

    +

    Safety Outlier Explorer Module - UI

    +

    safety_outlier_explorer()

    +

    Safety Outlier Explorer

    +

    safety_results_over_time()

    +

    Safety Results Over Time plot

    +

    tendril_chart()

    +

    Tendril plot

    +
    + + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/init_aeExplorer.html b/docs/reference/init_aeExplorer.html new file mode 100644 index 0000000..174c4a7 --- /dev/null +++ b/docs/reference/init_aeExplorer.html @@ -0,0 +1,169 @@ + + + + + + + + +Initialize Settings for Adverse Event Explorer widget — init_aeExplorer • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Initialize Settings for Adverse Event Explorer widget

    + Source: R/init_aeExplorer.R + +
    + +
    +

    Initialize Settings for Adverse Event Explorer widget

    +
    + + 
    init_aeExplorer(data, settings)
    + +

    Arguments

    + + + + + + + + + + +
    data

    labs data structured as one record per person per visit per measurement. See details for column requirements.

    settings

    named list of settings

    + +

    Value

    + +

    returns list with data and settings

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/init_aeTimelines.html b/docs/reference/init_aeTimelines.html new file mode 100644 index 0000000..3d40989 --- /dev/null +++ b/docs/reference/init_aeTimelines.html @@ -0,0 +1,169 @@ + + + + + + + + +Initialize Settings for AE Timeline widget — init_aeTimelines • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Initialize Settings for AE Timeline widget

    + Source: R/init_aeTimelines.R + +
    + +
    +

    Initialize Settings for AE Timeline widget

    +
    + + 
    init_aeTimelines(data, settings)
    + +

    Arguments

    + + + + + + + + + + +
    data

    labs data structured as one record per person per visit per measurement. See details for column requirements.

    settings

    named list of settings

    + +

    Value

    + +

    returns list with data and settings

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/init_paneledOutlierExplorer.html b/docs/reference/init_paneledOutlierExplorer.html new file mode 100644 index 0000000..a16400c --- /dev/null +++ b/docs/reference/init_paneledOutlierExplorer.html @@ -0,0 +1,169 @@ + + + + + + + + +Initialize Settings for Paneled Outlier Explorer widget — init_paneledOutlierExplorer • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Initialize Settings for Paneled Outlier Explorer widget

    + Source: R/init_paneledOutlierExplorer.R + +
    + +
    +

    Initialize Settings for Paneled Outlier Explorer widget

    +
    + + 
    init_paneledOutlierExplorer(data, settings)
    + +

    Arguments

    + + + + + + + + + + +
    data

    labs data structured as one record per person per visit per measurement. See details for column requirements.

    settings

    named list of settings

    + +

    Value

    + +

    returns list with data and settings

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/init_safetyOutlierExplorer.html b/docs/reference/init_safetyOutlierExplorer.html new file mode 100644 index 0000000..f6de562 --- /dev/null +++ b/docs/reference/init_safetyOutlierExplorer.html @@ -0,0 +1,169 @@ + + + + + + + + +Initialize Settings for Safety Outlier Explorer widget — init_safetyOutlierExplorer • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Initialize Settings for Safety Outlier Explorer widget

    + Source: R/init_safetyOutlierExplorer.R + +
    + +
    +

    Initialize Settings for Safety Outlier Explorer widget

    +
    + + 
    init_safetyOutlierExplorer(data, settings)
    + +

    Arguments

    + + + + + + + + + + +
    data

    labs data structured as one record per person per visit per measurement. See details for column requirements.

    settings

    named list of settings

    + +

    Value

    + +

    returns list with data and settings

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/init_safetyResultsOverTime.html b/docs/reference/init_safetyResultsOverTime.html new file mode 100644 index 0000000..4beccfe --- /dev/null +++ b/docs/reference/init_safetyResultsOverTime.html @@ -0,0 +1,169 @@ + + + + + + + + +Initialize Settings for Safety Results Over Time widget — init_safetyResultsOverTime • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Initialize Settings for Safety Results Over Time widget

    + Source: R/init_safetyResultsOverTime.R + +
    + +
    +

    Initialize Settings for Safety Results Over Time widget

    +
    + + 
    init_safetyResultsOverTime(data, settings)
    + +

    Arguments

    + + + + + + + + + + +
    data

    labs data structured as one record per person per visit per measurement. See details for column requirements.

    settings

    named list of settings

    + +

    Value

    + +

    returns list with data and settings

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/init_safetyShiftPlot.html b/docs/reference/init_safetyShiftPlot.html new file mode 100644 index 0000000..b845834 --- /dev/null +++ b/docs/reference/init_safetyShiftPlot.html @@ -0,0 +1,169 @@ + + + + + + + + +Initialize Settings for Safety Shift Plot widget — init_safetyShiftPlot • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Initialize Settings for Safety Shift Plot widget

    + Source: R/init_safetyShiftPlot.R + +
    + +
    +

    Initialize Settings for Safety Shift Plot widget

    +
    + + 
    init_safetyShiftPlot(data, settings)
    + +

    Arguments

    + + + + + + + + + + +
    data

    labs data structured as one record per person per visit per measurement. See details for column requirements.

    settings

    named list of settings

    + +

    Value

    + +

    returns list with data and settings

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/lab_distribution_server.html b/docs/reference/lab_distribution_server.html new file mode 100644 index 0000000..3a82386 --- /dev/null +++ b/docs/reference/lab_distribution_server.html @@ -0,0 +1,177 @@ + + + + + + + + +lab distribution Module - Server — lab_distribution_server • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    lab distribution Module - Server

    + Source: R/mod_lab_distribution.R + +
    + +
    +

    A simple server for a shiny module looking at lab histograms. Intended primarily for technical demos.

    +
    + + 
    lab_distribution_server(input, output, session, params)
    + +

    Arguments

    + + + + + + + + + + + + + + + + + + +
    input

    module input

    output

    module output

    session

    module session

    params

    parameters object with data and settings options.

    + +

    Value

    + +

    returns shiny module Server function

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/lab_distribution_ui.html b/docs/reference/lab_distribution_ui.html new file mode 100644 index 0000000..96f22bd --- /dev/null +++ b/docs/reference/lab_distribution_ui.html @@ -0,0 +1,165 @@ + + + + + + + + +Lab distribution Module - UI — lab_distribution_ui • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Lab distribution Module - UI

    + Source: R/mod_lab_distribution.R + +
    + +
    +

    A simple UI for a shiny module looking at lab histograms. Intended primarily for technical demos.

    +
    + + 
    lab_distribution_ui(id)
    + +

    Arguments

    + + + + + + +
    id

    module id

    + +

    Value

    + +

    returns shiny module UI

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/meta_aes.html b/docs/reference/meta_aes.html new file mode 100644 index 0000000..d232690 --- /dev/null +++ b/docs/reference/meta_aes.html @@ -0,0 +1,173 @@ + + + + + + + + +Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the ae domain. One record per unique data mapping — meta_aes • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the ae domain. One record per unique data mapping

    + Source: R/meta.R + +
    + +
    +

    Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the ae domain. One record per unique data mapping

    +
    + + 
    meta_aes
    + + +

    Format

    + +

    A data frame with X rows and 10 columns

    +
    domain

    Data domain

    +
    text_key

    Text key indicating the setting name. '--' delimiter indicates a field level data mapping

    +
    col_key

    Key for the column mapping

    +
    field_key

    Key for the field mapping (if any)

    +
    type

    type of mapping - "field" or "column"

    +
    label

    Label

    +
    description

    Description

    +
    multiple

    Mapping supports multiple columns/fields

    +
    standard_adam

    Default values for the ADaM data standard

    +
    standard_sdtm

    Default values for the SDTM data standard

    + +
    + +

    Source

    + +

    Created for this package

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/meta_dm.html b/docs/reference/meta_dm.html new file mode 100644 index 0000000..8342c09 --- /dev/null +++ b/docs/reference/meta_dm.html @@ -0,0 +1,173 @@ + + + + + + + + +Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the dm domain. One record per unique data mapping — meta_dm • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the dm domain. One record per unique data mapping

    + Source: R/meta.R + +
    + +
    +

    Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the dm domain. One record per unique data mapping

    +
    + + 
    meta_dm
    + + +

    Format

    + +

    A data frame with X rows and 10 columns

    +
    domain

    Data domain

    +
    text_key

    Text key indicating the setting name. '--' delimiter indicates a field level data mapping

    +
    col_key

    Key for the column mapping

    +
    field_key

    Key for the field mapping (if any)

    +
    type

    type of mapping - "field" or "column"

    +
    label

    Label

    +
    description

    Description

    +
    multiple

    Mapping supports multiple columns/fields

    +
    standard_adam

    Default values for the ADaM data standard

    +
    standard_sdtm

    Default values for the SDTM data standard

    + +
    + +

    Source

    + +

    Created for this package

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/meta_ecg.html b/docs/reference/meta_ecg.html new file mode 100644 index 0000000..2b36754 --- /dev/null +++ b/docs/reference/meta_ecg.html @@ -0,0 +1,173 @@ + + + + + + + + +Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the ecg domain. One record per unique data mapping — meta_ecg • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the ecg domain. One record per unique data mapping

    + Source: R/meta.R + +
    + +
    +

    Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the ecg domain. One record per unique data mapping

    +
    + + 
    meta_ecg
    + + +

    Format

    + +

    A data frame with 22 rows and 10 columns

    +
    domain

    Data domain

    +
    text_key

    Text key indicating the setting name. '--' delimiter indicates a field level data mapping

    +
    col_key

    Key for the column mapping

    +
    field_key

    Key for the field mapping (if any)

    +
    type

    type of mapping - "field" or "column"

    +
    label

    Label

    +
    description

    Description

    +
    multiple

    Mapping supports multiple columns/fields

    +
    standard_adam

    Default values for the ADaM data standard

    +
    standard_sdtm

    Default values for the SDTM data standard

    + +
    + +

    Source

    + +

    Created for this package

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/meta_hepExplorer.html b/docs/reference/meta_hepExplorer.html new file mode 100644 index 0000000..02d2ae5 --- /dev/null +++ b/docs/reference/meta_hepExplorer.html @@ -0,0 +1,173 @@ + + + + + + + + +Metadata data frame containing information about the data mapping used to configure safetyGraphics for the hepExplorer Chart. One record per unique data mapping — meta_hepExplorer • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Metadata data frame containing information about the data mapping used to configure safetyGraphics for the hepExplorer Chart. One record per unique data mapping

    + Source: R/meta.R + +
    + +
    +

    Metadata data frame containing information about the data mapping used to configure safetyGraphics for the hepExplorer Chart. One record per unique data mapping

    +
    + + 
    meta_hepExplorer
    + + +

    Format

    + +

    A data frame with X rows and 10 columns

    +
    domain

    Data domain

    +
    text_key

    Text key indicating the setting name. '--' delimiter indicates a field level data mapping

    +
    col_key

    Key for the column mapping

    +
    field_key

    Key for the field mapping (if any)

    +
    type

    type of mapping - "field" or "column"

    +
    label

    Label

    +
    description

    Description

    +
    multiple

    Mapping supports multiple columns/fields

    +
    standard_adam

    Default values for the ADaM data standard

    +
    standard_sdtm

    Default values for the SDTM data standard

    + +
    + +

    Source

    + +

    Created for this package

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/meta_labs.html b/docs/reference/meta_labs.html new file mode 100644 index 0000000..ee73393 --- /dev/null +++ b/docs/reference/meta_labs.html @@ -0,0 +1,173 @@ + + + + + + + + +Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the labs domain. One record per unique data mapping — meta_labs • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the labs domain. One record per unique data mapping

    + Source: R/meta.R + +
    + +
    +

    Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the labs domain. One record per unique data mapping

    +
    + + 
    meta_labs
    + + +

    Format

    + +

    A data frame with X rows and 10 columns

    +
    domain

    Data domain

    +
    text_key

    Text key indicating the setting name. '--' delimiter indicates a field level data mapping

    +
    col_key

    Key for the column mapping

    +
    field_key

    Key for the field mapping (if any)

    +
    type

    type of mapping - "field" or "column"

    +
    label

    Label

    +
    description

    Description

    +
    multiple

    Mapping supports multiple columns/fields

    +
    standard_adam

    Default values for the ADaM data standard

    +
    standard_sdtm

    Default values for the SDTM data standard

    + +
    + +

    Source

    + +

    Created for this package

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/render_widget.html b/docs/reference/render_widget.html new file mode 100644 index 0000000..90c04ff --- /dev/null +++ b/docs/reference/render_widget.html @@ -0,0 +1,170 @@ + + + + + + + + +Render an htmlwidget using standard safetyGraphics workflow — render_widget • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Render an htmlwidget using standard safetyGraphics workflow

    + Source: R/render_widget.R + +
    + +
    +

    Render an htmlwidget using standard safetyGraphics workflow

    +
    + + 
    render_widget(widgetName, data, mapping)
    + +

    Arguments

    + + + + + + + + + + + + + + +
    widgetName

    name of the widget saved in safetyCharts

    data

    named list of current data sets

    mapping

    named list with the current data mappings

    + + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/safetyOutlierExplorer_server.html b/docs/reference/safetyOutlierExplorer_server.html new file mode 100644 index 0000000..6e1e314 --- /dev/null +++ b/docs/reference/safetyOutlierExplorer_server.html @@ -0,0 +1,177 @@ + + + + + + + + +Safety Outlier Explorer Module - UI — safetyOutlierExplorer_server • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Safety Outlier Explorer Module - UI

    + Source: R/mod_safetyOutlierExplorer.R + +
    + +
    +

    Safety Outlier Explorer Module - UI

    +
    + + 
    safetyOutlierExplorer_server(input, output, session, params)
    + +

    Arguments

    + + + + + + + + + + + + + + + + + + +
    input

    module input

    output

    module output

    session

    module session

    params

    parameters object with data and settings options.

    + +

    Value

    + +

    returns shiny module Server function

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/safetyOutlierExplorer_ui.html b/docs/reference/safetyOutlierExplorer_ui.html new file mode 100644 index 0000000..9a41732 --- /dev/null +++ b/docs/reference/safetyOutlierExplorer_ui.html @@ -0,0 +1,165 @@ + + + + + + + + +Safety Outlier Explorer Module - UI — safetyOutlierExplorer_ui • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Safety Outlier Explorer Module - UI

    + Source: R/mod_safetyOutlierExplorer.R + +
    + +
    +

    Safety Outlier Explorer Module - UI

    +
    + + 
    safetyOutlierExplorer_ui(id)
    + +

    Arguments

    + + + + + + +
    id

    module id

    + +

    Value

    + +

    returns shiny module UI

    + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/safety_outlier_explorer-1.png b/docs/reference/safety_outlier_explorer-1.png new file mode 100644 index 0000000000000000000000000000000000000000..897c7817b44d94dd18a28d8bd26e63f2b8298dd2 GIT binary patch literal 514205 zcmeFZcQn?295;N4P}w6hD@h0mNmf~9%giQZ@4Y2EBq4-Q#$}VeHzCR1JK1}$=Y9Rw zec#VH_j&$#&U4Ol&V8M4zsC7p*YzFm&-?vaAHfQ8lDJnXuObi#+-Fb4o+A*KT@VO# z18hwAm$8_XP52GdKw44^euvkQXq7kocE#rD3ws3OMj+}JTExPZ5duMncqaB(+2zyf zgzHCYl?vfa>x~nx`+`(a??fXt9<2V>=u)B?v<30y!5p) z9a&Ym+^@Oe8u6@;8&~YVm$H4AQVrt2zlw45;%pKT{`(qW#&ih|`uAlMW`5N;1m1ryMi($?$t~G_dew`^66XuzKsE?`2W(^l}Xg>4QdvQ zt!=9^lcc*vGDfuBj5S9t*gX`uINd2pOJD}S(Ls`deAJ!WUzzGvpMA710#vhhZ}TmRnD0SrtR zQ;Crp_Xl|Vf9R?&&QG>06qw&US}#Z6s5zkFio;P>@lR#`v$WKZd~y2flTG8509P&d zwUWbSwYu+g)|c1oF1$?QF=hK~`V}Q*|L4n#YGqcH9j$h~f1OR8j+Qm#QfLd8zx1xP zQnkj5-j$2pjArj--iQ(i6Z5whW<{>Wo~U5RiDSBM~}AF zti7pr7JCBQ<{Ges4EUE_Axtq+aWB6x5)NKs~%k&jamm zB_$n;G3?qQCfph&3sfC>+EoP}M|RZqUH3NKYOwvE9G)%;M_|#oAhujQWOm-R&8e4K 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Outlier Explorer — safety_outlier_explorer • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +

    +
    + + + + +
    + +
    +
    +
    +

    Safety Outlier Explorer

    + Source: R/safety_outlier_explorer.R + +
    + +
    +

    Safety Outlier Explorer

    +
    + + 
    safety_outlier_explorer(data, settings)
    + +

    Arguments

    + + + + + + + + + + +
    data

    labs data structured as one record per person per visit per measurement. See details for column requirements.

    settings

    named list of settings with the parameters specified below.

    + +

    Value

    + +

    returns a chart object

    +

    Details

    + +

    The settings object provides details the columns in the data set.

    +
      +

    • "id_col"ID column

      • +

    • "value_col"Value column

      • +

    • "measure_col"Measure column

      • +

    • "measure_values"Measure values

      • +

    • "studyday_col"Study Day (numeric)

      • +
    + + +

    Examples

    + 
    
+settings <- list(
+    id_col = "USUBJID",
+    measure_col = "LBTEST",
+    measure_values = c("Albumin", "Bilirubin", "Chloride"),
+    studyday_col = "VISITDY",
+    value_col = "LBORRES"
+)
+safety_outlier_explorer(safetyData::sdtm_lb, settings)
+
    #> Warning: Removed 28 row(s) containing missing values (geom_path).
    +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/docs/reference/safety_results_over_time-1.png b/docs/reference/safety_results_over_time-1.png new file mode 100644 index 0000000000000000000000000000000000000000..0706e361aac1d75ba7f7ccd48e0b07c7a5b7e173 GIT binary patch literal 114180 zcmce;2T&Akv@JU31egJdDp7Kl3@QqPB*_^R$w|o>)L&2$kU>B|l4OP;VHn9E3IY;` zjDQk^A!j7t-Qa)TJ?GYYujM!rp7IwRXQ$QIaJ+Np%v1LXo27WK>b8 zBW@_vp$Es0!f*N`66fK+qYv)N%E13{tluj2h5t@GlGAZSp=bk;e+NRw7EDp7%P6$W z4RyEo(*y2r7+k$~ceSP@%>>4qn_s)G7L{9@IDQ#BDa(WB%|V@bOPb8a%yrqt?=a?| zV^0+xC8qzFDPJ@P!kGe_uXg{r^3&`!pHKcX<_G zX^^M=eU|6%2kSP6DJs*0gUL#3(nV_WIT~j#KN`duuCOU8DD==GqYlSUZPx+kNHTg! z8&}FHhlQ^cQ<>PDzE;nue=jh>^1blmn?^f}kuzi_27{|b_|TuW%ul4HEB}1uo+dN7 z{Zi)Ux|boQqpj^qNI-~ciaJ}0jSxH9%HBS*WxPP-LoKHM;ajCNCiJgI+E1jbe!rl) z%N41{7xk9$$g>;IZ(fOEu;O@r^TvXkK4x@nv$Lzq%uy!jtAJwD_wRC;GQ-@fp)Z=w z3dUIou%Q>-#5o_Ac6lf&D>vqIT=GwxowX~iu@vU#=jT&Y!*mb`CXNC@EOa4Q6;?Tn zsF>K8OQ~&edLCmKddxut{W>ucqm&k2|Bw-FYiql>xh*8yp`G8GrJC`U@!Exx*C@^71e7F9f&<0M)A`KMFGgS>Rr 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z2nd$$2sa}dltq9-%s{sw0JXPaVNqIdNW?0>9&M}jxwu%q<#??_xTJfngzc=ol7xTY z8tM`Q=izUXEfA+PCT8i)`1eK+ay+!O&91LLl)Go^%e^O-QcGf2zOY}@ct)c(W?;ay zc203)Jk*J3Dk=&2@f`%4XtBzM?HEGD0!X(Bk$8kVEud^$kxxw=UD?GIPz4!HSkki5 zFp8W|M|RMxW(&Mk)G|Pc!NsyS#dw$N_0?&yo&}%ncFi2_H?lk7TJ`?PQtjaS zf}E7NCE1PP#fdlHZuzO7=%!~8dH&_O8Yc@@|ML7Z!QV`uHDBGSeh;!3bzg|`hu|#N z_SCNB>UF;JcMl(-UGk!)uDR6n&@sw$Rb{@cTgqYZh38kRisJYGeEyS+X9HrQ|M&<$ zAb0rhhouml?a7TB*xPvKnq&trzIdQklFZx`*RYhP<)Evl&4RRjQ#a=Gcxd))I5 zv>jV421?huxVsCc%XBkaHVIriq9d(Sb4bpYt^4fMWRLgx?8a<^=xeg->W`mhII=7C zaJi*a$6Jb@XK6nC*Bh$0G(I(3I>2?-+nrs(zMFACM8Dl9?L3F1y!Li#U=5pO+_AC# z18Ys)$WM_;xjxe;BIu3P=&3-3MybG_I!JG9zYo~!X54IfZt?7^RDb!nyL(^Man-{u zwXG5UyD$F=6&TV}+4-XnsTfp`I($DqG(`?XcZN8wB7fO_m N%1Xx-6Xeg`{$J$;& + + + + + + + +Safety Results Over Time plot — safety_results_over_time • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + diff --git a/docs/reference/tendril_chart.html b/docs/reference/tendril_chart.html new file mode 100644 index 0000000..2c8ec46 --- /dev/null +++ b/docs/reference/tendril_chart.html @@ -0,0 +1,182 @@ + + + + + + + + +Tendril plot — tendril_chart • safetyCharts + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
    +
    + + + + +
    + +
    +
    +
    +

    Tendril plot

    + Source: R/tendril_chart.R + +
    + +
    +

    Create a plot using the Tendril package

    +
    + + 
    tendril_chart(data, settings)
    + +

    Arguments

    + + + + + + + + + + +
    data

    list of data frames including dataframes named aes (adverse events) and dm (demographics)

    settings

    named list of domain-specific settings with the parameters specified below.

    + +

    Value

    + +

    returns a chart object

    +

    Details

    + +

    The settings object provides details regarding the columns in the data sets.

    +
      +

    • "settings$dm$id_col"ID column

      • +

    • "settings$dm$treatment_col"Treatment column

      • +

    • "settings$dm$treatment_values--group1"Name of treatment 1

      • +

    • "settings$dm$treatment_values--group2"Name of treatment 2

      • +

    • "settings$aes$id_col"ID column)

      • +

    • "settings$aes$bodsys_col"Body System

      • +

    • "settings$aes$stdy_col"Study Day

      • +
    + + +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +
    + + + + + + + + diff --git a/man/paneledOutlierExplorer.Rd b/man/paneledOutlierExplorer.Rd new file mode 100644 index 0000000..f2b1933 --- /dev/null +++ b/man/paneledOutlierExplorer.Rd @@ -0,0 +1,81 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/paneledOutlierExplorer.R +\name{paneledOutlierExplorer} +\alias{paneledOutlierExplorer} +\title{Make standalone paneledOutlierExplorer html widget} +\usage{ +paneledOutlierExplorer(df = safetyData::adam_adlbc, mapping = NULL, ...) +} +\arguments{ +\item{df}{data frame containing lab data used to render for paneledOutlierExplorer. Default is safetyData::adam_adlbc.} + +\item{mapping}{named list with the current data mappings. See details for default mapping.} + +\item{...}{additional options to be added to mapping. Will overwrite mapping.} +} +\description{ +Convience mapping of render_widget for paneledOutlierExplorer. +} +\details{ +The \href{https://github.com/Rhoinc/paneled-outlier-explorer/wiki/Data-Guidelines}{data} and \href{https://github.com/RhoInc/paneled-outlier-explorer/wiki/Configuration}{mapping} should match the specs described in the \href{https://github.com/rhoinc/paneled-outlier-explorer/wiki/Configuration}{paneledOutlierExplorer} javascript library. Items passed in ... are added to mapping, and then the list is converted to json via \code{jsonlite::toJSON(mapping, auto_unbox=TRUE, null="null")}. + +The default mapping shown below is designed to work with data in the CDISC ADaM format (like \code{safetydata::adam_adlbc}).\preformatted{mapping <- list( + measure_col = 'PARAM', + time_cols = list( + list( + value_col = "VISIT", + order_col = "VISITNUM", + label = "VISIT", + type = 'ordinal', + label="Visit", + rotate_tick_labels = TRUE, + vertical_space = 75 + ), + list( + value_col = "ADY", + order_col = "ADY", + label = "Study Day", + type = 'linear', + label="Visit", + rotate_tick_labels = FALSE, + vertical_space = 0 + ) + ), + value_col = 'AVAL', + id_col = 'USUBJID', + lln_col = 'A1LO', + uln_col = 'A1HI' + ) +} + +Parameters that are not included in the default mapping can be accessed via ...; Key options and defaults for safetyData::adam_adlbc shown below: +\itemize{ +\item \code{filters}: list of columns to be included as data filters formatted as `filters=c("SEX","AGEGR1")``) +} + +For more options see the \href{https://github.com/rhoinc/paneled-outlier-explorer/wiki/Configuration}{full specs} in the javascript library. +} +\examples{ +\dontrun{ +# Render widget with defaults +paneledOutlierExplorer() + +# Add Sex and Age Filters +paneledOutlierExplorer( + filters=list( + list(value_col="SEX"), + list(value_col="AGEGR1",label="Age") + ) +) + +# customize panel size (in pixels) +paneledOutlierExplorer(multiples_sizing=list("width"= 500,"height"= 300)) + +# customize default normal range +paneledOutlierExplorer( + normal_range_method = 'quantiles', + normal_range_quantile_low = 0.2, + normal_range_quantile_high = 0.8, +) +} +} From dc69443845c0cb74c1b50930b8919a839587aa30 Mon Sep 17 00:00:00 2001 From: Preston Burns Date: Mon, 18 Jul 2022 11:02:13 -0400 Subject: [PATCH 09/50] enable rendering of aeexplorer without treatment_col --- R/init_aeExplorer.R | 14 ++++++++++++++ 1 file changed, 14 insertions(+) diff --git a/R/init_aeExplorer.R b/R/init_aeExplorer.R index 922d99e..ae95e12 100644 --- a/R/init_aeExplorer.R +++ b/R/init_aeExplorer.R @@ -9,6 +9,13 @@ init_aeExplorer <- function(data, settings) { + + #if no treatment_col provided, create dummy treatment_col for group setting so that ae explorer JS doesn't bomb + if (trimws(settings[["dm"]][["treatment_col"]])=="" | is.null(settings[["dm"]][["treatment_col"]])){ + data$dm <- data$dm %>% mutate(group_placeholder="All") + settings[["dm"]][["treatment_col"]] <- "group_placeholder" + } + # Merge treatment with adverse events. dm_sub <- data$dm %>% select(settings[["dm"]][["id_col"]], settings[["dm"]][["treatment_col"]]) anly <- dm_sub %>% left_join(data$aes) # left join to keep all rows in dm (even if there were no AEs) @@ -37,5 +44,12 @@ init_aeExplorer <- function(data, settings) { values = c("", NA, NULL) ) ) + + #if no treatment_col provided, remove total column and group selection dropdown + if ( settings[["dm"]][["treatment_col"]] == "group_placeholder"){ + ae_settings$defaults[["groupCols"]] = FALSE + ae_settings$defaults[["useVariableControls"]] = FALSE + } + return(list(data = anly, settings = ae_settings)) } From 626be47eb7c10456c979ebef6dcc36535e6c8857 Mon Sep 17 00:00:00 2001 From: Preston Burns Date: Mon, 18 Jul 2022 12:07:24 -0400 Subject: [PATCH 10/50] add documentation of dependencies --- DESCRIPTION | 1 + NAMESPACE | 1 + R/init_aeExplorer.R | 3 +++ 3 files changed, 5 insertions(+) diff --git a/DESCRIPTION b/DESCRIPTION index 13406e3..cf5489e 100644 --- a/DESCRIPTION +++ b/DESCRIPTION @@ -25,6 +25,7 @@ Imports: htmlwidgets, huxtable, jsonlite, + magrittr, pharmaRTF, plotly, purrr, diff --git a/NAMESPACE b/NAMESPACE index e1a00ce..75cae13 100644 --- a/NAMESPACE +++ b/NAMESPACE @@ -38,6 +38,7 @@ importFrom(huxtable,set_escape_contents) importFrom(huxtable,set_valign) importFrom(huxtable,set_width) importFrom(jsonlite,toJSON) +importFrom(magrittr,"%>%") importFrom(pharmaRTF,add_footnotes) importFrom(pharmaRTF,add_titles) importFrom(pharmaRTF,hf_line) diff --git a/R/init_aeExplorer.R b/R/init_aeExplorer.R index ae95e12..567e15d 100644 --- a/R/init_aeExplorer.R +++ b/R/init_aeExplorer.R @@ -5,6 +5,9 @@ #' #' @return returns list with data and settings #' +#' @importFrom magrittr %>% +#' @import dplyr +#' #' @export From a811c6aa0c92ee51c6e8571d7af8f4426ec6f9c2 Mon Sep 17 00:00:00 2001 From: Preston Burns Date: Mon, 18 Jul 2022 12:35:12 -0400 Subject: [PATCH 11/50] create single flag at the beginning to avoid hiding trt when user-specified treatment_col is group_placeholder --- R/init_aeExplorer.R | 9 ++++++--- 1 file changed, 6 insertions(+), 3 deletions(-) diff --git a/R/init_aeExplorer.R b/R/init_aeExplorer.R index 567e15d..fa6c88d 100644 --- a/R/init_aeExplorer.R +++ b/R/init_aeExplorer.R @@ -13,9 +13,12 @@ init_aeExplorer <- function(data, settings) { + # crates flag if treatment_col is missing to trigger actions to avoid downstream JS errors and enable visualization of blinded(no trt) data + missing_trt_flag <- trimws(settings[["dm"]][["treatment_col"]])=="" | is.null(settings[["dm"]][["treatment_col"]]) + #if no treatment_col provided, create dummy treatment_col for group setting so that ae explorer JS doesn't bomb - if (trimws(settings[["dm"]][["treatment_col"]])=="" | is.null(settings[["dm"]][["treatment_col"]])){ - data$dm <- data$dm %>% mutate(group_placeholder="All") + if (missing_trt_flag){ + data$dm <- data$dm %>% mutate(group_placeholder=TRUE) settings[["dm"]][["treatment_col"]] <- "group_placeholder" } @@ -49,7 +52,7 @@ init_aeExplorer <- function(data, settings) { ) #if no treatment_col provided, remove total column and group selection dropdown - if ( settings[["dm"]][["treatment_col"]] == "group_placeholder"){ + if (missing_trt_flag){ ae_settings$defaults[["groupCols"]] = FALSE ae_settings$defaults[["useVariableControls"]] = FALSE } From f20b4d1be9160662c392f31109c88987d38087cb Mon Sep 17 00:00:00 2001 From: Preston Burns Date: Mon, 18 Jul 2022 12:37:05 -0400 Subject: [PATCH 12/50] keep placeholder type char for js sake --- R/init_aeExplorer.R | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/R/init_aeExplorer.R b/R/init_aeExplorer.R index fa6c88d..9d93bdf 100644 --- a/R/init_aeExplorer.R +++ b/R/init_aeExplorer.R @@ -18,7 +18,7 @@ init_aeExplorer <- function(data, settings) { #if no treatment_col provided, create dummy treatment_col for group setting so that ae explorer JS doesn't bomb if (missing_trt_flag){ - data$dm <- data$dm %>% mutate(group_placeholder=TRUE) + data$dm <- data$dm %>% mutate(group_placeholder="All") settings[["dm"]][["treatment_col"]] <- "group_placeholder" } From aa3c7da04f2f5000a7a4d81059ff85b32e789294 Mon Sep 17 00:00:00 2001 From: Preston Burns Date: Mon, 18 Jul 2022 12:40:11 -0400 Subject: [PATCH 13/50] clean up my spelling --- R/init_aeExplorer.R | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/R/init_aeExplorer.R b/R/init_aeExplorer.R index 9d93bdf..a56eef8 100644 --- a/R/init_aeExplorer.R +++ b/R/init_aeExplorer.R @@ -13,7 +13,7 @@ init_aeExplorer <- function(data, settings) { - # crates flag if treatment_col is missing to trigger actions to avoid downstream JS errors and enable visualization of blinded(no trt) data + # creates flag if treatment_col is missing to trigger actions to avoid downstream JS errors and enable visualization of blinded(no treatment_col) data missing_trt_flag <- trimws(settings[["dm"]][["treatment_col"]])=="" | is.null(settings[["dm"]][["treatment_col"]]) #if no treatment_col provided, create dummy treatment_col for group setting so that ae explorer JS doesn't bomb From ecd22af0d254ab9aa82980eff8c71ef1dbd27d73 Mon Sep 17 00:00:00 2001 From: Preston Burns Date: Mon, 18 Jul 2022 12:55:16 -0400 Subject: [PATCH 14/50] handle both NULL and "". Comes from safetygraphics as empty string but covering both. --- R/init_aeExplorer.R | 6 +++++- 1 file changed, 5 insertions(+), 1 deletion(-) diff --git a/R/init_aeExplorer.R b/R/init_aeExplorer.R index a56eef8..f30a2b6 100644 --- a/R/init_aeExplorer.R +++ b/R/init_aeExplorer.R @@ -14,7 +14,11 @@ init_aeExplorer <- function(data, settings) { # creates flag if treatment_col is missing to trigger actions to avoid downstream JS errors and enable visualization of blinded(no treatment_col) data - missing_trt_flag <- trimws(settings[["dm"]][["treatment_col"]])=="" | is.null(settings[["dm"]][["treatment_col"]]) + missing_trt_flag <- ifelse(is.null(settings[["dm"]][["treatment_col"]]), + TRUE, + ifelse(trimws(settings[["dm"]][["treatment_col"]]) == "", + TRUE, + FALSE)) #if no treatment_col provided, create dummy treatment_col for group setting so that ae explorer JS doesn't bomb if (missing_trt_flag){ From bb585317a37c5b27ff6a0b8d9a68e12c84edeac0 Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Mon, 18 Jul 2022 13:28:42 -0400 Subject: [PATCH 15/50] fix #116 --- DESCRIPTION | 2 +- NAMESPACE | 1 + R/aeExplorer.R | 96 +++++++++++++++++++++++++++++++++++ R/init_aeExplorer.R | 9 ++-- man/aeExplorer.Rd | 71 ++++++++++++++++++++++++++ man/hepExplorer.Rd | 6 ++- man/paneledOutlierExplorer.Rd | 6 ++- 7 files changed, 183 insertions(+), 8 deletions(-) create mode 100644 R/aeExplorer.R create mode 100644 man/aeExplorer.Rd diff --git a/DESCRIPTION b/DESCRIPTION index cf5489e..7750e07 100644 --- a/DESCRIPTION +++ b/DESCRIPTION @@ -15,7 +15,7 @@ BugReports: https://github.com/SafetyGraphics/safetyCharts/issues License: MIT + file LICENSE Encoding: UTF-8 LazyData: true -RoxygenNote: 7.1.2 +RoxygenNote: 7.2.0 Roxygen: list(markdown = TRUE) Imports: dplyr, diff --git a/NAMESPACE b/NAMESPACE index 75cae13..badc119 100644 --- a/NAMESPACE +++ b/NAMESPACE @@ -3,6 +3,7 @@ export(QT_OutlierExplorer_server) export(QT_OutlierExplorer_ui) export(QT_Outlier_Explorer) +export(aeExplorer) export(demogRTF_server) export(demogRTF_table) export(demogRTF_ui) diff --git a/R/aeExplorer.R b/R/aeExplorer.R new file mode 100644 index 0000000..47c8722 --- /dev/null +++ b/R/aeExplorer.R @@ -0,0 +1,96 @@ +#' Make standalone aeExplorer html widget +#' +#' Convience mapping of render_widget for aeExplorer. +#' +#' @details The [data](https://github.com/RhoInc/aeexplorer/wiki/Data-Guidelines) and +#' [mapping](https://github.com/RhoInc/aeexplorer/wiki/Configuration) should match the specs +#' described in the [aeExplorer](https://github.com/RhoInc/aeexplorer/wiki/Configuration) +#' JavaScript library. Items passed in ... are added to mapping, and then the list is converted to +#' JSON via `jsonlite::toJSON(mapping, auto_unbox=TRUE, NULL="NULL")`. +#' +#' The default mapping shown below is designed to work with data in the CDISC ADaM format (like +#' `safetydata::adam_adlbc`). +#' +#' ``` +#' mapping <- list( +#' dm = list( +#' id_col = 'USUBJID', +#' treatment_col = 'ARM' +#' ), +#' aes = list( +#' id_col = 'USUBJID', +#' bodsys_col = 'AEBODSYS', +#' term_col = 'AEDECOD' +#' ) +#' ) +#' ``` +#' +#' Parameters that are not included in the default mapping can be accessed via .... +#' +#' For more options see the [full specs](https://github.com/RhoInc/aeexplorer/wiki/Configuration) in +#' the JavaScript library. +#' +#' @examples +#' \dontrun{ +#' # Render widget with defaults. +#' aeExplorer() +#' +#' # Render widget without stratification. +#' aeExplorer( +#' mapping = list( +#' dm = list( +#' id_col = 'USUBJID' +#' ), +#' aes = list( +#' id_col = 'USUBJID', +#' bodsys_col = 'AEBODSYS', +#' term_col = 'AEDECOD' +#' ) +#' ) +#' ) +#' } +#' +#' @param df data frame containing lab data used to render for aeExplorer. Default is safetyData::adam_adlbc. +#' @param mapping named list with the current data mappings. See details for default mapping. +#' @param ... additional options to be added to mapping. Will overwrite mapping. +#' +#' @importFrom purrr list_modify +#' +#' @export + +aeExplorer <- function( + data = list( + dm = safetyData::sdtm_dm, + aes = safetyData::sdtm_ae + ), + mapping = NULL, + ... +) { + # Default mapping - TODO: retrieve mapping from a dedicated file or object (in safetyGraphics?). + if (is.null(mapping)) { + mapping <- list( + dm = list( + id_col = 'USUBJID', + treatment_col = 'ARM' + ), + aes = list( + id_col = 'USUBJID', + bodsys_col = 'AEBODSYS', + term_col = 'AEDECOD' + ) + ) + } + + # Add ... to mapping. + if (length(list(...)) > 0) { + mapping <- purrr::list_modify(mapping, !!!list(...)) + } + + initialized <- init_aeExplorer( + data = data, + settings = mapping + ) + + # Render widget as standalone HTML page. + render_widget("aeExplorer", initialized$data, initialized$settings) +} diff --git a/R/init_aeExplorer.R b/R/init_aeExplorer.R index a56eef8..a83dff7 100644 --- a/R/init_aeExplorer.R +++ b/R/init_aeExplorer.R @@ -14,10 +14,13 @@ init_aeExplorer <- function(data, settings) { # creates flag if treatment_col is missing to trigger actions to avoid downstream JS errors and enable visualization of blinded(no treatment_col) data - missing_trt_flag <- trimws(settings[["dm"]][["treatment_col"]])=="" | is.null(settings[["dm"]][["treatment_col"]]) - + missing_trt_flag <- ( + is.null(settings[["dm"]][["treatment_col"]]) || # Check NULL first and evaluate logic left to right + trimws(settings[["dm"]][["treatment_col"]])=="" + ) + #if no treatment_col provided, create dummy treatment_col for group setting so that ae explorer JS doesn't bomb - if (missing_trt_flag){ + if (missing_trt_flag) { data$dm <- data$dm %>% mutate(group_placeholder="All") settings[["dm"]][["treatment_col"]] <- "group_placeholder" } diff --git a/man/aeExplorer.Rd b/man/aeExplorer.Rd new file mode 100644 index 0000000..8aeb594 --- /dev/null +++ b/man/aeExplorer.Rd @@ -0,0 +1,71 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/aeExplorer.R +\name{aeExplorer} +\alias{aeExplorer} +\title{Make standalone aeExplorer html widget} +\usage{ +aeExplorer( + data = list(dm = safetyData::sdtm_dm, aes = safetyData::sdtm_ae), + mapping = NULL, + ... +) +} +\arguments{ +\item{mapping}{named list with the current data mappings. See details for default mapping.} + +\item{...}{additional options to be added to mapping. Will overwrite mapping.} + +\item{df}{data frame containing lab data used to render for aeExplorer. Default is safetyData::adam_adlbc.} +} +\description{ +Convience mapping of render_widget for aeExplorer. +} +\details{ +The \href{https://github.com/RhoInc/aeexplorer/wiki/Data-Guidelines}{data} and +\href{https://github.com/RhoInc/aeexplorer/wiki/Configuration}{mapping} should match the specs +described in the \href{https://github.com/RhoInc/aeexplorer/wiki/Configuration}{aeExplorer} +JavaScript library. Items passed in ... are added to mapping, and then the list is converted to +JSON via \code{jsonlite::toJSON(mapping, auto_unbox=TRUE, NULL="NULL")}. + +The default mapping shown below is designed to work with data in the CDISC ADaM format (like +\code{safetydata::adam_adlbc}). + +\if{html}{\out{
    }}\preformatted{mapping <- list( + dm = list( + id_col = 'USUBJID', + treatment_col = 'ARM' + ), + aes = list( + id_col = 'USUBJID', + bodsys_col = 'AEBODSYS', + term_col = 'AEDECOD' + ) +) +}\if{html}{\out{
    }} + +Parameters that are not included in the default mapping can be accessed via .... + +For more options see the \href{https://github.com/RhoInc/aeexplorer/wiki/Configuration}{full specs} in +the JavaScript library. +} +\examples{ +\dontrun{ +# Render widget with defaults. +aeExplorer() + +# Render widget without stratification. +aeExplorer( + mapping = list( + dm = list( + id_col = 'USUBJID' + ), + aes = list( + id_col = 'USUBJID', + bodsys_col = 'AEBODSYS', + term_col = 'AEDECOD' + ) + ) +) +} + +} diff --git a/man/hepExplorer.Rd b/man/hepExplorer.Rd index 0b92f07..f48f8e5 100644 --- a/man/hepExplorer.Rd +++ b/man/hepExplorer.Rd @@ -19,7 +19,9 @@ Convience mapping of render_widget for hepExplorer. \details{ The \href{https://github.com/SafetyGraphics/hep-explorer/wiki/Data-Guidelines}{data} and \href{https://github.com/SafetyGraphics/hep-explorer/wiki/Configuration}{mapping} should match the specs described in the \href{https://github.com/SafetyGraphics/hep-explorer/wiki/Configuration}{hepExplorer} javascript library. Items passed in ... are added to mapping, and then the list is converted to json via \code{jsonlite::toJSON(mapping, auto_unbox=TRUE, null="null")}. -The default mapping shown below is designed to work with data in the CDISC ADaM format (like \code{safetydata::adam_adlbc}).\preformatted{mapping <- list( +The default mapping shown below is designed to work with data in the CDISC ADaM format (like \code{safetydata::adam_adlbc}). + +\if{html}{\out{
    }}\preformatted{mapping <- list( measure_col = "PARAM", measure_values = list( ALT = "Alanine Aminotransferase (U/L)", @@ -35,7 +37,7 @@ The default mapping shown below is designed to work with data in the CDISC ADaM visit_col = "VISIT", visitn_col = "VISITNUM" ) -} +}\if{html}{\out{
    }} Parameters that are not included in the default mapping can be accessed via ...; Key options and defaults for safetyData::adam_adlbc shown below: \itemize{ diff --git a/man/paneledOutlierExplorer.Rd b/man/paneledOutlierExplorer.Rd index f2b1933..b5d4b9b 100644 --- a/man/paneledOutlierExplorer.Rd +++ b/man/paneledOutlierExplorer.Rd @@ -19,7 +19,9 @@ Convience mapping of render_widget for paneledOutlierExplorer. \details{ The \href{https://github.com/Rhoinc/paneled-outlier-explorer/wiki/Data-Guidelines}{data} and \href{https://github.com/RhoInc/paneled-outlier-explorer/wiki/Configuration}{mapping} should match the specs described in the \href{https://github.com/rhoinc/paneled-outlier-explorer/wiki/Configuration}{paneledOutlierExplorer} javascript library. Items passed in ... are added to mapping, and then the list is converted to json via \code{jsonlite::toJSON(mapping, auto_unbox=TRUE, null="null")}. -The default mapping shown below is designed to work with data in the CDISC ADaM format (like \code{safetydata::adam_adlbc}).\preformatted{mapping <- list( +The default mapping shown below is designed to work with data in the CDISC ADaM format (like \code{safetydata::adam_adlbc}). + +\if{html}{\out{
    }}\preformatted{mapping <- list( measure_col = 'PARAM', time_cols = list( list( @@ -46,7 +48,7 @@ The default mapping shown below is designed to work with data in the CDISC ADaM lln_col = 'A1LO', uln_col = 'A1HI' ) -} +}\if{html}{\out{
    }} Parameters that are not included in the default mapping can be accessed via ...; Key options and defaults for safetyData::adam_adlbc shown below: \itemize{ From 39e4c7f9e6d6969c49e8b068cf8452cba0e6cf17 Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Thu, 23 Feb 2023 10:30:11 -0500 Subject: [PATCH 16/50] broke something --- inst/htmlwidgets/aeTimelines.js | 60 +++++++++++++++++---------------- 1 file changed, 31 insertions(+), 29 deletions(-) diff --git a/inst/htmlwidgets/aeTimelines.js b/inst/htmlwidgets/aeTimelines.js index 39989e7..f2b4a50 100644 --- a/inst/htmlwidgets/aeTimelines.js +++ b/inst/htmlwidgets/aeTimelines.js @@ -1,30 +1,32 @@ HTMLWidgets.widget({ - - name: 'aeTimelines', - - type: 'output', - - factory: function(el, width, height) { - - return { - - renderValue: function(x) { - - el.innerHTML = ""; - x.data = HTMLWidgets.dataframeToD3(x.data); - console.log(x.settings); - - let wrapID = "#"+d3.select(el).property("id"); - aeTimelines(wrapID, x.settings).init(x.data); - - }, - - resize: function(width, height) { - - // TODO: code to re-render the widget with a new size - - } - - }; - } -}); \ No newline at end of file + name: 'aeTimelines', + type: 'output', + factory: function(el, width, height) { + return { + renderValue: function(x) { + el.innerHTML = ""; + x.data = HTMLWidgets.dataframeToD3(x.data); + console.log(x.settings); + let wrapID = "#"+d3.select(el).property("id"); + const instance = aeTimelines(wrapID, x.settings).init(x.data); + + // Communicate participantsSelected event with safetyGraphics when Shiny exists in + // the environment. + if (!!Shiny) { + instance.wrap.on('participantsSelected', function() { + console.log('Participant Selected Event:'); + console.log(d3.event.data); + const namespace = el.id.split('-')[0]; + console.log(namespace); + Shiny.setInputValue( + `${namespace}-participants_selected`, + d3.event.data + ); + }); + } + }, + resize: function(width, height) { + } + }; + } +}); From 02e03fdd8a042e7b7a325ecf83806cc9a59a71f2 Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Fri, 24 Feb 2023 16:37:26 -0500 Subject: [PATCH 17/50] fix #125 --- inst/htmlwidgets/aeExplorer.js | 35 +---------- inst/htmlwidgets/aeExplorer.yaml | 9 ++- inst/htmlwidgets/aeTimelines.js | 33 +--------- inst/htmlwidgets/aeTimelines.yaml | 11 +++- inst/htmlwidgets/hepExplorer.js | 24 +------- inst/htmlwidgets/hepExplorer.yaml | 9 ++- inst/htmlwidgets/lib/addClickListener.js | 23 +++++++ inst/htmlwidgets/lib/defineWidget.js | 35 +++++++++++ .../safetyDeltaDelta.js | 5 ++ inst/htmlwidgets/nepExplorer.js | 33 +--------- inst/htmlwidgets/nepExplorer.yaml | 9 ++- inst/htmlwidgets/paneledOutlierExplorer.js | 32 +--------- inst/htmlwidgets/paneledOutlierExplorer.yaml | 9 ++- inst/htmlwidgets/safetyDeltaDelta.js | 60 +------------------ inst/htmlwidgets/safetyDeltaDelta.yaml | 9 ++- inst/htmlwidgets/safetyHistogram.js | 33 +--------- inst/htmlwidgets/safetyHistogram.yaml | 9 ++- inst/htmlwidgets/safetyOutlierExplorer.js | 32 +--------- inst/htmlwidgets/safetyOutlierExplorer.yaml | 9 ++- inst/htmlwidgets/safetyResultsOverTime.js | 34 +---------- inst/htmlwidgets/safetyResultsOverTime.yaml | 9 ++- inst/htmlwidgets/safetyShiftPlot.js | 35 +---------- inst/htmlwidgets/safetyShiftPlot.yaml | 9 ++- 23 files changed, 154 insertions(+), 352 deletions(-) create mode 100644 inst/htmlwidgets/lib/addClickListener.js create mode 100644 inst/htmlwidgets/lib/defineWidget.js diff --git a/inst/htmlwidgets/aeExplorer.js b/inst/htmlwidgets/aeExplorer.js index 500bcb7..26e6806 100644 --- a/inst/htmlwidgets/aeExplorer.js +++ b/inst/htmlwidgets/aeExplorer.js @@ -1,34 +1 @@ -HTMLWidgets.widget({ - - name: 'aeExplorer', - - type: 'output', - - factory: function(el, width, height) { - - // return = widget instance object - return { - - // renderValue delivers data & settings to the DOM element - // x = data & settings - renderValue: function(x) { - - el.innerHTML = ""; - - x.data = HTMLWidgets.dataframeToD3(x.data); - - console.log(x.settings); - console.log(x.settings.variables.filters); - - aeTable.createChart(el, x.settings).init(x.data); - }, - - resize: function(width, height) { - - // TODO: code to re-render the widget with a new size - - } - - }; - } -}); \ No newline at end of file +defineWidget('aeExplorer', aeTable.createChart); diff --git a/inst/htmlwidgets/aeExplorer.yaml b/inst/htmlwidgets/aeExplorer.yaml index cab2be6..b47f589 100644 --- a/inst/htmlwidgets/aeExplorer.yaml +++ b/inst/htmlwidgets/aeExplorer.yaml @@ -8,4 +8,11 @@ dependencies: src: htmlwidgets/lib/aeexplorer-3.4.1 script: aeTable.js stylesheet: aeTable.css - + - name: addClickListener + script: addClickListener.js + src: htmlwidgets/lib/ + version: 1.0.0 + - name: defineWidget + script: defineWidget.js + src: htmlwidgets/lib/ + version: 1.0.0 diff --git a/inst/htmlwidgets/aeTimelines.js b/inst/htmlwidgets/aeTimelines.js index f2b4a50..0fbf299 100644 --- a/inst/htmlwidgets/aeTimelines.js +++ b/inst/htmlwidgets/aeTimelines.js @@ -1,32 +1 @@ -HTMLWidgets.widget({ - name: 'aeTimelines', - type: 'output', - factory: function(el, width, height) { - return { - renderValue: function(x) { - el.innerHTML = ""; - x.data = HTMLWidgets.dataframeToD3(x.data); - console.log(x.settings); - let wrapID = "#"+d3.select(el).property("id"); - const instance = aeTimelines(wrapID, x.settings).init(x.data); - - // Communicate participantsSelected event with safetyGraphics when Shiny exists in - // the environment. - if (!!Shiny) { - instance.wrap.on('participantsSelected', function() { - console.log('Participant Selected Event:'); - console.log(d3.event.data); - const namespace = el.id.split('-')[0]; - console.log(namespace); - Shiny.setInputValue( - `${namespace}-participants_selected`, - d3.event.data - ); - }); - } - }, - resize: function(width, height) { - } - }; - } -}); +defineWidget('aeTimelines', aeTimelines); diff --git a/inst/htmlwidgets/aeTimelines.yaml b/inst/htmlwidgets/aeTimelines.yaml index fb8b241..b1391ef 100644 --- a/inst/htmlwidgets/aeTimelines.yaml +++ b/inst/htmlwidgets/aeTimelines.yaml @@ -11,5 +11,12 @@ dependencies: - name: ae-timelines version: 2.1.6 src: htmlwidgets/lib/ae-timelines-2.1.6 - script: aeTimelines.js - + script: aeTimelines.js + - name: addClickListener + script: addClickListener.js + src: htmlwidgets/lib/ + version: 1.0.0 + - name: defineWidget + script: defineWidget.js + src: htmlwidgets/lib/ + version: 1.0.0 diff --git a/inst/htmlwidgets/hepExplorer.js b/inst/htmlwidgets/hepExplorer.js index d63f87d..ec32127 100644 --- a/inst/htmlwidgets/hepExplorer.js +++ b/inst/htmlwidgets/hepExplorer.js @@ -1,23 +1 @@ -HTMLWidgets.widget({ - name: "hepExplorer", - type: "output", - - factory: function(el, width, height) { - - return { - renderValue: function(rSettings) { - console.log(rSettings) - el.innerHTML="" - let settings = rSettings.settings; - let data = HTMLWidgets.dataframeToD3(rSettings.data); - let wrapID = rSettings.ns ? "#"+rSettings.ns : "#"+d3.select(el).property("id"); - var chart = hepexplorer(wrapID, settings) - chart.init(data); - }, - resize: function(width, height) { - // TODO: code to re-render the widget with a new size - } - - }; - } -}); +defineWidget('hepExplorer', hepexplorer); diff --git a/inst/htmlwidgets/hepExplorer.yaml b/inst/htmlwidgets/hepExplorer.yaml index 4e1cda9..62cd9ad 100644 --- a/inst/htmlwidgets/hepExplorer.yaml +++ b/inst/htmlwidgets/hepExplorer.yaml @@ -12,4 +12,11 @@ dependencies: version: 1.4.2 src: htmlwidgets/lib/hep-explorer-1.4.2 script: hepexplorer.js - + - name: addClickListener + script: addClickListener.js + src: htmlwidgets/lib/ + version: 1.0.0 + - name: defineWidget + script: defineWidget.js + src: htmlwidgets/lib/ + version: 1.0.0 diff --git a/inst/htmlwidgets/lib/addClickListener.js b/inst/htmlwidgets/lib/addClickListener.js new file mode 100644 index 0000000..9491057 --- /dev/null +++ b/inst/htmlwidgets/lib/addClickListener.js @@ -0,0 +1,23 @@ +// Communicate participantsSelected event with safetyGraphics when Shiny exists in the environment. +const addClickListener = function(instance, el) { + console.log(instance); + if (!!Shiny) { + const wrap = instance.hasOwnProperty('chart') + ? instance.chart.wrap + : instance.wrap; + + if (wrap !== undefined) + wrap.on('participantsSelected', function() { + console.log( + `Selected participant ID: ${d3.event.data}` + ); + + const namespace = el.id.split('-')[0]; + + Shiny.setInputValue( + `${namespace}-participants_selected`, + d3.event.data + ); + }); + } +} diff --git a/inst/htmlwidgets/lib/defineWidget.js b/inst/htmlwidgets/lib/defineWidget.js new file mode 100644 index 0000000..845e97c --- /dev/null +++ b/inst/htmlwidgets/lib/defineWidget.js @@ -0,0 +1,35 @@ +const defineWidget = function(name, fn) { + HTMLWidgets.widget({ + name: name, + type: "output", + factory: function(el, width, height) { + return { + renderValue: function(inputs) { + // clear element + el.innerHTML = ""; + + // define widget inputs + const wrapID = inputs.ns + ? `#${inputs.ns}` + : `#${d3.select(el).property("id")}`; + const settings = inputs.settings; + const data = HTMLWidgets.dataframeToD3(inputs.data); + + // instantiate widget + const instance = fn( + wrapID, + settings + ); + + // render widget + instance.init(data); + + // add click event listener to send particpiant ID to safetyGraphics + addClickListener(instance, el); + }, + resize: function(width, height) { + } + }; + } + }); +} diff --git a/inst/htmlwidgets/lib/safety-delta-delta-1.0.0/safetyDeltaDelta.js b/inst/htmlwidgets/lib/safety-delta-delta-1.0.0/safetyDeltaDelta.js index f05d5a2..cf38fe2 100644 --- a/inst/htmlwidgets/lib/safety-delta-delta-1.0.0/safetyDeltaDelta.js +++ b/inst/htmlwidgets/lib/safety-delta-delta-1.0.0/safetyDeltaDelta.js @@ -1219,6 +1219,11 @@ .attr('stroke-width', 3) .attr('stroke', 'black'); drawMeasureTable.call(chart, d); + + //Trigger participantsSelected event + chart.participantsSelected = [d.key]; + chart.events.participantsSelected.data = chart.participantsSelected; + chart.wrap.node().dispatchEvent(chart.events.participantsSelected); }); } diff --git a/inst/htmlwidgets/nepExplorer.js b/inst/htmlwidgets/nepExplorer.js index 00cdc36..283eaca 100644 --- a/inst/htmlwidgets/nepExplorer.js +++ b/inst/htmlwidgets/nepExplorer.js @@ -1,32 +1 @@ -HTMLWidgets.widget({ - - name: 'nepExplorer', - - type: 'output', - - factory: function (el, width, height) { - - - return { - - renderValue: function (x) { - - el.innerHTML = ""; - - x.data = HTMLWidgets.dataframeToD3(x.data); - - console.log(x.settings); - - nepExplorer(el, x.settings).init(x.data); - - }, - - resize: function (width, height) { - - // TODO: code to re-render the widget with a new size - - } - - }; - } -}); \ No newline at end of file +defineWidget('nepExplorer', nepExplorer); diff --git a/inst/htmlwidgets/nepExplorer.yaml b/inst/htmlwidgets/nepExplorer.yaml index 16f3d81..0535b4e 100644 --- a/inst/htmlwidgets/nepExplorer.yaml +++ b/inst/htmlwidgets/nepExplorer.yaml @@ -12,4 +12,11 @@ dependencies: version: 0.9.0 src: htmlwidgets/lib/nep-explorer-0.9.0 script: nepExplorer.js - + - name: addClickListener + script: addClickListener.js + src: htmlwidgets/lib/ + version: 1.0.0 + - name: defineWidget + script: defineWidget.js + src: htmlwidgets/lib/ + version: 1.0.0 diff --git a/inst/htmlwidgets/paneledOutlierExplorer.js b/inst/htmlwidgets/paneledOutlierExplorer.js index bba7960..850a1cf 100644 --- a/inst/htmlwidgets/paneledOutlierExplorer.js +++ b/inst/htmlwidgets/paneledOutlierExplorer.js @@ -1,31 +1 @@ -HTMLWidgets.widget({ - - name: 'paneledOutlierExplorer', - - type: 'output', - - factory: function(el, width, height) { - - // TODO: define shared variables for this instance - - return { - - renderValue: function(x) { - - el.innerHTML = ""; - - x.data = HTMLWidgets.dataframeToD3(x.data); - - paneledOutlierExplorer(el, x.settings).init(x.data); - - }, - - resize: function(width, height) { - - // TODO: code to re-render the widget with a new size - - } - - }; - } -}); +defineWidget('paneledOutlierExplorer', paneledOutlierExplorer); diff --git a/inst/htmlwidgets/paneledOutlierExplorer.yaml b/inst/htmlwidgets/paneledOutlierExplorer.yaml index 964abdd..717c511 100644 --- a/inst/htmlwidgets/paneledOutlierExplorer.yaml +++ b/inst/htmlwidgets/paneledOutlierExplorer.yaml @@ -12,4 +12,11 @@ dependencies: version: 1.1.4 src: htmlwidgets/lib/paneled-outlier-explorer-1.1.4 script: paneledOutlierExplorer.js - + - name: addClickListener + script: addClickListener.js + src: htmlwidgets/lib/ + version: 1.0.0 + - name: defineWidget + script: defineWidget.js + src: htmlwidgets/lib/ + version: 1.0.0 diff --git a/inst/htmlwidgets/safetyDeltaDelta.js b/inst/htmlwidgets/safetyDeltaDelta.js index f2ff162..a8ecaa8 100644 --- a/inst/htmlwidgets/safetyDeltaDelta.js +++ b/inst/htmlwidgets/safetyDeltaDelta.js @@ -1,59 +1 @@ -HTMLWidgets.widget({ - name: "safetyDeltaDelta", - type: "output", - - factory: function(el, width, height) { - - return { - renderValue: function(rSettings) { - console.log("widget started ...") - console.log(el) - console.log(rSettings) - //console.log(rSettings) - //el.innerHTML = "
    "; - el.innerHTML="" - let settings = rSettings.settings; - let data = HTMLWidgets.dataframeToD3(rSettings.data); - let wrapID = rSettings.ns ? "#"+rSettings.ns : "#"+d3.select(el).property("id"); - var chart = safetyDeltaDelta(wrapID, settings) - chart.init(data); - }, - resize: function(width, height) { - // TODO: code to re-render the widget with a new size - } - - }; - } -}); -//HTMLWidgets.widget({ -// -// name: 'safetyDeltaDelta', -// -// type: 'output', -// -// factory: function(el, width, height) { -// -// -// return { -// -// renderValue: function(x) { -// -// el.innerHTML = ""; -// -// x.data = HTMLWidgets.dataframeToD3(x.data); -// -// console.log(x.settings); -// -// safetyDeltaDelta(el, x.settings).init(x.data); -// -// }, -// -// resize: function(width, height) { -// -// // TODO: code to re-render the widget with a new size -// -// } -// -// }; -// } -//}); +defineWidget('safetyDeltaDelta', safetyDeltaDelta); diff --git a/inst/htmlwidgets/safetyDeltaDelta.yaml b/inst/htmlwidgets/safetyDeltaDelta.yaml index 3599759..438cd88 100644 --- a/inst/htmlwidgets/safetyDeltaDelta.yaml +++ b/inst/htmlwidgets/safetyDeltaDelta.yaml @@ -12,4 +12,11 @@ dependencies: version: 1.0.0 src: htmlwidgets/lib/safety-delta-delta-1.0.0 script: safetyDeltaDelta.js - + - name: addClickListener + script: addClickListener.js + src: htmlwidgets/lib/ + version: 1.0.0 + - name: defineWidget + script: defineWidget.js + src: htmlwidgets/lib/ + version: 1.0.0 diff --git a/inst/htmlwidgets/safetyHistogram.js b/inst/htmlwidgets/safetyHistogram.js index 6afb600..f55c61d 100644 --- a/inst/htmlwidgets/safetyHistogram.js +++ b/inst/htmlwidgets/safetyHistogram.js @@ -1,32 +1 @@ -HTMLWidgets.widget({ - - name: 'safetyHistogram', - - type: 'output', - - factory: function(el, width, height) { - - - return { - - renderValue: function(x) { - - el.innerHTML = ""; - - x.data = HTMLWidgets.dataframeToD3(x.data); - - console.log(x.settings); - - safetyHistogram(el, x.settings).init(x.data); - - }, - - resize: function(width, height) { - - // TODO: code to re-render the widget with a new size - - } - - }; - } -}); \ No newline at end of file +defineWidget('safetyHistogram', safetyHistogram); diff --git a/inst/htmlwidgets/safetyHistogram.yaml b/inst/htmlwidgets/safetyHistogram.yaml index a563adc..5524286 100644 --- a/inst/htmlwidgets/safetyHistogram.yaml +++ b/inst/htmlwidgets/safetyHistogram.yaml @@ -12,4 +12,11 @@ dependencies: version: 2.5.0 src: htmlwidgets/lib/safety-histogram-2.5.0 script: safetyHistogram.js - + - name: addClickListener + script: addClickListener.js + src: htmlwidgets/lib/ + version: 1.0.0 + - name: defineWidget + script: defineWidget.js + src: htmlwidgets/lib/ + version: 1.0.0 diff --git a/inst/htmlwidgets/safetyOutlierExplorer.js b/inst/htmlwidgets/safetyOutlierExplorer.js index 38afa76..03fd965 100644 --- a/inst/htmlwidgets/safetyOutlierExplorer.js +++ b/inst/htmlwidgets/safetyOutlierExplorer.js @@ -1,31 +1 @@ -HTMLWidgets.widget({ - - name: 'safetyOutlierExplorer', - - type: 'output', - - factory: function(el, width, height) { - - // TODO: define shared variables for this instance - - return { - - renderValue: function(x) { - - el.innerHTML = ""; - - x.data = HTMLWidgets.dataframeToD3(x.data); - - safetyOutlierExplorer(el, x.settings).init(x.data); - - }, - - resize: function(width, height) { - - // TODO: code to re-render the widget with a new size - - } - - }; - } -}); \ No newline at end of file +defineWidget('safetyOutlierExplorer', safetyOutlierExplorer); diff --git a/inst/htmlwidgets/safetyOutlierExplorer.yaml b/inst/htmlwidgets/safetyOutlierExplorer.yaml index cbe61cb..61006e9 100644 --- a/inst/htmlwidgets/safetyOutlierExplorer.yaml +++ b/inst/htmlwidgets/safetyOutlierExplorer.yaml @@ -12,4 +12,11 @@ dependencies: version: 2.7.0 src: htmlwidgets/lib/safety-outlier-explorer-2.7.0 script: safetyOutlierExplorer.js - + - name: addClickListener + script: addClickListener.js + src: htmlwidgets/lib/ + version: 1.0.0 + - name: defineWidget + script: defineWidget.js + src: htmlwidgets/lib/ + version: 1.0.0 diff --git a/inst/htmlwidgets/safetyResultsOverTime.js b/inst/htmlwidgets/safetyResultsOverTime.js index 47cdb49..666c70d 100644 --- a/inst/htmlwidgets/safetyResultsOverTime.js +++ b/inst/htmlwidgets/safetyResultsOverTime.js @@ -1,33 +1 @@ -HTMLWidgets.widget({ - - name: 'safetyResultsOverTime', - - type: 'output', - - factory: function(el, width, height) { - - // TODO: define shared variables for this instance - - return { - - renderValue: function(x) { - - el.innerHTML = ""; - - x.data = HTMLWidgets.dataframeToD3(x.data); - - console.log(x.settings); - - safetyResultsOverTime(el, x.settings).init(x.data); - - }, - - resize: function(width, height) { - - // TODO: code to re-render the widget with a new size - - } - - }; - } -}); \ No newline at end of file +defineWidget('safetyResultsOverTime', safetyResultsOverTime); diff --git a/inst/htmlwidgets/safetyResultsOverTime.yaml b/inst/htmlwidgets/safetyResultsOverTime.yaml index e9e16bd..a628f15 100644 --- a/inst/htmlwidgets/safetyResultsOverTime.yaml +++ b/inst/htmlwidgets/safetyResultsOverTime.yaml @@ -12,4 +12,11 @@ dependencies: version: 2.3.3 src: htmlwidgets/lib/safety-results-over-time-2.3.3 script: safetyResultsOverTime.js - + - name: addClickListener + script: addClickListener.js + src: htmlwidgets/lib/ + version: 1.0.0 + - name: defineWidget + script: defineWidget.js + src: htmlwidgets/lib/ + version: 1.0.0 diff --git a/inst/htmlwidgets/safetyShiftPlot.js b/inst/htmlwidgets/safetyShiftPlot.js index 0a7407d..e7dbee3 100644 --- a/inst/htmlwidgets/safetyShiftPlot.js +++ b/inst/htmlwidgets/safetyShiftPlot.js @@ -1,34 +1 @@ -HTMLWidgets.widget({ - - name: 'safetyShiftPlot', - - type: 'output', - - factory: function(el, width, height) { - - // TODO: define shared variables for this instance - - return { - - renderValue: function(x) { - - el.innerHTML = ""; - - x.data = HTMLWidgets.dataframeToD3(x.data); - - console.log(x.settings); - let wrapID = x.ns ? "#"+x.ns : "#"+d3.select(el).property("id"); - - safetyShiftPlot(wrapID, x.settings).init(x.data); - - }, - - resize: function(width, height) { - - // TODO: code to re-render the widget with a new size - - } - - }; - } -}); \ No newline at end of file +defineWidget('safetyShiftPlot', safetyShiftPlot); diff --git a/inst/htmlwidgets/safetyShiftPlot.yaml b/inst/htmlwidgets/safetyShiftPlot.yaml index f53cdee..775f698 100644 --- a/inst/htmlwidgets/safetyShiftPlot.yaml +++ b/inst/htmlwidgets/safetyShiftPlot.yaml @@ -12,4 +12,11 @@ dependencies: version: 2.1.3 src: htmlwidgets/lib/safety-shift-plot-2.1.3 script: safetyShiftPlot.js - + - name: addClickListener + script: addClickListener.js + src: htmlwidgets/lib/ + version: 1.0.0 + - name: defineWidget + script: defineWidget.js + src: htmlwidgets/lib/ + version: 1.0.0 From f304100dcb4a345a9cdb96294a1dde2f0d13219e Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Fri, 24 Feb 2023 17:20:20 -0500 Subject: [PATCH 18/50] document --- DESCRIPTION | 2 +- man/hepExplorer.Rd | 6 ++++-- 2 files changed, 5 insertions(+), 3 deletions(-) diff --git a/DESCRIPTION b/DESCRIPTION index 13406e3..1e5d716 100644 --- a/DESCRIPTION +++ b/DESCRIPTION @@ -15,7 +15,7 @@ BugReports: https://github.com/SafetyGraphics/safetyCharts/issues License: MIT + file LICENSE Encoding: UTF-8 LazyData: true -RoxygenNote: 7.1.2 +RoxygenNote: 7.2.2 Roxygen: list(markdown = TRUE) Imports: dplyr, diff --git a/man/hepExplorer.Rd b/man/hepExplorer.Rd index 0b92f07..f48f8e5 100644 --- a/man/hepExplorer.Rd +++ b/man/hepExplorer.Rd @@ -19,7 +19,9 @@ Convience mapping of render_widget for hepExplorer. \details{ The \href{https://github.com/SafetyGraphics/hep-explorer/wiki/Data-Guidelines}{data} and \href{https://github.com/SafetyGraphics/hep-explorer/wiki/Configuration}{mapping} should match the specs described in the \href{https://github.com/SafetyGraphics/hep-explorer/wiki/Configuration}{hepExplorer} javascript library. Items passed in ... are added to mapping, and then the list is converted to json via \code{jsonlite::toJSON(mapping, auto_unbox=TRUE, null="null")}. -The default mapping shown below is designed to work with data in the CDISC ADaM format (like \code{safetydata::adam_adlbc}).\preformatted{mapping <- list( +The default mapping shown below is designed to work with data in the CDISC ADaM format (like \code{safetydata::adam_adlbc}). + +\if{html}{\out{
    }}\preformatted{mapping <- list( measure_col = "PARAM", measure_values = list( ALT = "Alanine Aminotransferase (U/L)", @@ -35,7 +37,7 @@ The default mapping shown below is designed to work with data in the CDISC ADaM visit_col = "VISIT", visitn_col = "VISITNUM" ) -} +}\if{html}{\out{
    }} Parameters that are not included in the default mapping can be accessed via ...; Key options and defaults for safetyData::adam_adlbc shown below: \itemize{ From d752579f504769c3fc1cb33a0c9f1aa3f75d522b Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Fri, 24 Feb 2023 17:24:18 -0500 Subject: [PATCH 19/50] update documentation --- R/hepExplorer.R | 10 +++++----- R/init_aeExplorer.R | 2 +- R/init_aeTimelines.R | 2 +- 3 files changed, 7 insertions(+), 7 deletions(-) diff --git a/R/hepExplorer.R b/R/hepExplorer.R index ed307f3..c6fd682 100644 --- a/R/hepExplorer.R +++ b/R/hepExplorer.R @@ -48,7 +48,7 @@ #' #' # Use custom mapping for SDTM data #' hepExplorer( -#' df=safetyData::sdtm_lb, +#' data=safetyData::sdtm_lb, #' measure_col = "LBTEST", #' measure_values = list( #' ALT = "Alanine Aminotransferase", @@ -66,7 +66,7 @@ #' ) #' } #' -#' @param df data frame containing lab data used to render for hepExplorer. Default is safetyData::adam_adlbc. +#' @param data data frame containing lab data used to render for hepExplorer. Default is safetyData::adam_adlbc. #' @param mapping named list with the current data mappings. See details for default mapping. #' @param ... additional options to be added to mapping. Will overwrite mapping. #' @@ -74,7 +74,7 @@ #' #' @export -hepExplorer <- function(df=safetyData::adam_adlbc, mapping=NULL, ...){ +hepExplorer <- function(data=safetyData::adam_adlbc, mapping=NULL, ...){ #default mapping if(is.null(mapping)){ @@ -102,5 +102,5 @@ hepExplorer <- function(df=safetyData::adam_adlbc, mapping=NULL, ...){ } # render widget as standalone html page - render_widget("hepExplorer" ,df, mapping) -} \ No newline at end of file + render_widget("hepExplorer" ,data, mapping) +} diff --git a/R/init_aeExplorer.R b/R/init_aeExplorer.R index 922d99e..8e876f9 100644 --- a/R/init_aeExplorer.R +++ b/R/init_aeExplorer.R @@ -1,6 +1,6 @@ #' Initialize Settings for Adverse Event Explorer widget #' -#' @param data labs data structured as one record per person per visit per measurement. See details for column requirements. +#' @param data adverse events data structured as one record per event. See details for column requirements. #' @param settings named list of settings #' #' @return returns list with data and settings diff --git a/R/init_aeTimelines.R b/R/init_aeTimelines.R index 2bac536..862ecc0 100644 --- a/R/init_aeTimelines.R +++ b/R/init_aeTimelines.R @@ -1,6 +1,6 @@ #' Initialize Settings for AE Timeline widget #' -#' @param data labs data structured as one record per person per visit per measurement. See details for column requirements. +#' @param data adverse events data structured as one record per event. See details for column requirements. #' @param settings named list of settings #' #' @return returns list with data and settings From 45536d6f3b4430578ec55c6b814167c8fb80dd19 Mon Sep 17 00:00:00 2001 From: Jeremy Wildfire Date: Fri, 17 Mar 2023 10:45:02 -0400 Subject: [PATCH 20/50] adding add metadata. refactor conmeds explorer chart --- R/init_cmExplorer.R | 6 +++--- data-raw/makeMeta.R | 4 ++++ data-raw/meta_cm.csv | 7 +++++++ data/meta_cm.rda | Bin 0 -> 527 bytes inst/config/cmExplorer.yaml | 2 +- 5 files changed, 15 insertions(+), 4 deletions(-) create mode 100644 data-raw/meta_cm.csv create mode 100644 data/meta_cm.rda diff --git a/R/init_cmExplorer.R b/R/init_cmExplorer.R index 0505831..cbe28b2 100644 --- a/R/init_cmExplorer.R +++ b/R/init_cmExplorer.R @@ -17,8 +17,8 @@ init_cmExplorer <- function(data, settings) { settings <- c(settings$cm, settings$labs) settings$variables <- list( - major = settings[["bodsys_col"]], - minor = settings[["term_col"]], + major = settings[["class_col"]], + minor = settings[["code_col"]], group = settings[["trt_col"]], id = paste0(settings[["id_col"]]), filters = list(), @@ -34,7 +34,7 @@ init_cmExplorer <- function(data, settings) { settings$defaults <- list( placeholderFlag = list( - valueCol = settings[["bodsys_col"]], + valueCol = settings[["class_col"]], values = c("", NA, NULL) ) ) diff --git a/data-raw/makeMeta.R b/data-raw/makeMeta.R index 989bee3..51cd4a7 100644 --- a/data-raw/makeMeta.R +++ b/data-raw/makeMeta.R @@ -17,6 +17,10 @@ usethis::use_data(meta_labs, overwrite = TRUE) meta_aes<-read_csv("data-raw/meta_aes.csv")[] usethis::use_data(meta_aes, overwrite = TRUE) +#cm +meta_cm<-read_csv("data-raw/meta_cm.csv")[] +usethis::use_data(meta_cm, overwrite = TRUE) + #dm meta_dm<-read_csv("data-raw/meta_dm.csv")[] usethis::use_data(meta_dm, overwrite = TRUE) diff --git a/data-raw/meta_cm.csv b/data-raw/meta_cm.csv new file mode 100644 index 0000000..74c0c56 --- /dev/null +++ b/data-raw/meta_cm.csv @@ -0,0 +1,7 @@ +text_key,domain,col_key,field_key,type,label,description,multiple,standard_adam,standard_sdtm +id_col,cm,id_col,,column,ID column,Unique subject identifier variable name.,FALSE,,USUBJID +seq_col,cm,seq_col,,column,Sequence column,Event sequence number variable name,FALSE,,CMSEQ +stdy_col,cm,stdy_col,,column,CM Start day column,Event start day variable name,FALSE,,CMSTDY +endy_col,cm,endy_col,,column,CM End day column,Event end day variable name,FALSE,,CMENDY +code_col,cm,code_col,,column,CM Code Column,Dictionary-derived low-level code,FALSE,,CMDECOD +class_col,cm,class_col,,column,CM Class System,Dictionary-derived high-level class,FALSE,,CMCLAS \ No newline at end of file diff --git a/data/meta_cm.rda b/data/meta_cm.rda new file mode 100644 index 0000000000000000000000000000000000000000..994734cb33b19e5391f3e31c55927a73decf2f9f GIT binary patch literal 527 zcmV+q0`UDpT4*^jL0KkKS!c!%4FCas|G@wI=!$4V5CA?mzF@!q|KLCX01?0e)~vy( zYH3D527np>10Vxw4{Crk0Fo(_M8YG`Ca07b zO*GI0Lq;K{nrHw$LB>p(F&LNuGGLhiG+`J57&sDuRRW<|k?CYcWSt4dNIyN9V*(6@ zhiw0Ml95r0VIA~BM3$p;LmNU!*I=YYeH3BZs^Ob0bWtWMi^5k4*t!l%E@G}oaP>=0 zF(h&%B*FyH(jlz`BqK97*@cLt#=~KTLRMX@CeS7q03sqJpd=J12%`Xz)8ibH)8{eQ za^kGvI7-ro_>_g2sa6@y9p+SfR$&36Cyq#Mxk6Z|y_1oS>wzN(9*;q~8=c&J;oa9C zcUYuMU=B=Bh$6{hIWSIT_1<*Y$cJ$-EgOXZ&2_~?mrQZJu{2N|0$a`Y*<~fhY%#jf ze&z<#2plyZ#xi1&$E1p)(_>Ri3WjS6uu#`Odtq;gHkrx13cGJ`mm?fnmy8qgrhU53 zW+Qyzu*ZEV5|dcSwh?r;x<@XtXr0lBG~|I<%+ieJVXHNUBsQ;ASM2gcrZyL46*!mT z7$VzEt2t~@fceVa!(D8DXsWZy-Tp^a(X$bkH-xt<=$#{oEtQS6cz{?5$%6#`!Y4XE RqA~xAxgwk>NHgOHhJbhh>AC;_ literal 0 HcmV?d00001 diff --git a/inst/config/cmExplorer.yaml b/inst/config/cmExplorer.yaml index 3988cb9..0c7281a 100644 --- a/inst/config/cmExplorer.yaml +++ b/inst/config/cmExplorer.yaml @@ -15,4 +15,4 @@ links: Wiki: https://github.com/RhoInc/aeexplorer/wiki Issues: https://github.com/RhoInc/aeexplorer/issues Demo: https://rhoinc.github.io/aeexplorer/test-page/ - safetyCharts: https://github.com/SafetyGraphics/safetycharts \ No newline at end of file + safetyCharts: https://github.com/SafetyGraphics/safetycharts From 1c90b23614c535092d11eff03b604b383443f532 Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Tue, 28 Mar 2023 17:12:03 -0400 Subject: [PATCH 21/50] fix #111 --- R/mod_demogRTF.R | 9 +++-- data-raw/meta_aes.csv | 18 +++++---- inst/config/QTOutlierExplorerModule.yaml | 8 ++++ inst/config/QTpaneledOutlierExplorer.yaml | 10 +++++ inst/config/QTsafetyDeltaDelta.yaml | 9 ++++- inst/config/QTsafetyHistogram.yaml | 7 ++++ inst/config/QTsafetyOutlierExplorer.yaml | 16 ++++++++ inst/config/QTsafetyResultsOverTime.yaml | 7 ++++ inst/config/QTsafetyShiftPlot.yaml | 7 ++++ inst/config/aeExplorer.yaml | 14 ++++++- inst/config/aeTimelines.yaml | 9 +++++ inst/config/demogRTF.yaml | 8 ++++ inst/config/hepExplorer.yaml | 10 +++++ inst/config/labdist.yaml | 4 ++ inst/config/paneledOutlierExplorer.yaml | 10 +++++ inst/config/safetyDeltaDelta.yaml | 7 ++++ inst/config/safetyHistogram.yaml | 7 ++++ inst/config/safetyOutlierExplorer.yaml | 16 ++++++++ inst/config/safetyOutlierExplorerModule.yaml | 6 +++ inst/config/safetyOutlierExplorerStatic.yaml | 6 +++ inst/config/safetyResultsOverTime.yaml | 7 ++++ inst/config/safetyResultsOverTimeStatic.yaml | 7 ++++ inst/config/safetyShiftPlot.yaml | 7 ++++ inst/config/tendril.yaml | 11 +++++- tests/testthat/test_check_config.R | 39 ++++++++++++++++++++ 25 files changed, 245 insertions(+), 14 deletions(-) create mode 100644 tests/testthat/test_check_config.R diff --git a/R/mod_demogRTF.R b/R/mod_demogRTF.R index 964c574..e0a25ca 100644 --- a/R/mod_demogRTF.R +++ b/R/mod_demogRTF.R @@ -78,10 +78,13 @@ demogRTF_table <- function(data, settings) { tplyr_tab <- Tplyr::tplyr_table(data, !!sym(settings$treatment_col)) %>% Tplyr::add_total_group() %>% Tplyr::add_layer( - Tplyr::group_count(!!sym(settings$race_col), by = "Race") + Tplyr::group_desc(!!sym(settings$age_col), by = "Age (Years)") ) %>% Tplyr::add_layer( - Tplyr::group_desc(!!sym(settings$age_col), by = "Age (Years)") + Tplyr::group_desc(!!sym(settings$sex_col), by = "Sex") + ) %>% + Tplyr::add_layer( + Tplyr::group_count(!!sym(settings$race_col), by = "Race") ) treatments<- data%>%pull(settings$treatment_col) %>% unique() @@ -118,4 +121,4 @@ demogRTF_table <- function(data, settings) { pharmaRTF::set_column_header_buffer(top=1) return(doc) -} \ No newline at end of file +} diff --git a/data-raw/meta_aes.csv b/data-raw/meta_aes.csv index d62b17b..f2e88c3 100644 --- a/data-raw/meta_aes.csv +++ b/data-raw/meta_aes.csv @@ -1,9 +1,11 @@ text_key,domain,col_key,field_key,type,label,description,multiple,standard_adam,standard_sdtm -id_col,aes,id_col,,column,ID column,Unique subject identifier variable name.,FALSE,USUBJID,USUBJID -seq_col,aes,seq_col,,column,Sequence column,Event sequence number variable name,FALSE,AESEQ,AESEQ -stdy_col,aes,stdy_col,,column,AE Start day column,Event start day variable name,FALSE,ASTDY,AESTDY -endy_col,aes,endy_col,,column,AE End day column,Event end day variable name,FALSE,AENDY,AEENDY -term_col,aes,term_col,,column,Preferred Term Column,Dictionary-Derived Term,FALSE,AEDECOD,AEDECOD -bodsys_col,aes,bodsys_col,,column,AE Body System,Body System or Organ Class,FALSE,AEBODSYS,AEBODSYS -severity_col,aes,severity_col,,column,AE Severity,AE Severity,FALSE,AESEV,AESEV -serious_col,aes,serious_col,,column,AE Seriousness,AE Seriousness,FALSE,AESER,AESER \ No newline at end of file +id_col,aes,id_col,,column,ID column,Unique subject identifier,FALSE,USUBJID,USUBJID +stdy_col,aes,stdy_col,,column,AE Start Day,Event start day,FALSE,ASTDY,AESTDY +endy_col,aes,endy_col,,column,AE End Day,Event end day,FALSE,AENDY,AEENDY +seq_col,aes,seq_col,,column,Sequence,Event sequence number,FALSE,AESEQ,AESEQ +term_col,aes,term_col,,column,Preferred Term,Dictionary-derived term,FALSE,AEDECOD,AEDECOD +bodsys_col,aes,bodsys_col,,column,AE Body System,Body system or organ class,FALSE,AEBODSYS,AEBODSYS +serious_col,aes,serious_col,,column,AE Seriousness,AE seriousness,FALSE,AESER,AESER +severity_col,aes,severity_col,,column,AE Severity,AE severity,FALSE,AESEV,AESEV +relationship_col,aes,relationship_col,,column,Relationship to Study Drug,Relationship to study drug,FALSE,AEREL,AEREL +outcome_col,aes,outcome_col,,column,AE Outcome,AE outcome,FALSE,AEOUT,AEOUT diff --git a/inst/config/QTOutlierExplorerModule.yaml b/inst/config/QTOutlierExplorerModule.yaml index a5bcbad..997e35d 100644 --- a/inst/config/QTOutlierExplorerModule.yaml +++ b/inst/config/QTOutlierExplorerModule.yaml @@ -7,6 +7,14 @@ export: true order: -37 domain: - ecg +dataSpec: + ecg: + - id_col + - visit_col + - visitn_col + - measure_col + - value_col + - baseline_flag_col workflow: ui: QT_OutlierExplorer_ui server: QT_OutlierExplorer_server diff --git a/inst/config/QTpaneledOutlierExplorer.yaml b/inst/config/QTpaneledOutlierExplorer.yaml index dcb9d6e..55dcde5 100644 --- a/inst/config/QTpaneledOutlierExplorer.yaml +++ b/inst/config/QTpaneledOutlierExplorer.yaml @@ -3,6 +3,16 @@ label: QT Paneled Outlier Explorer type: htmlwidget domain: - ecg +dataSpec: + ecg: + - id_col + - visit_col + - visitn_col + - studyday_col + - measure_col + - value_col + - normal_col_low + - normal_col_high package: safetyCharts export: true order: -32 diff --git a/inst/config/QTsafetyDeltaDelta.yaml b/inst/config/QTsafetyDeltaDelta.yaml index 0f7a5b2..99fd78a 100644 --- a/inst/config/QTsafetyDeltaDelta.yaml +++ b/inst/config/QTsafetyDeltaDelta.yaml @@ -5,7 +5,14 @@ package: safetyCharts export: true order: -36 domain: - ecg + - ecg +dataSpec: + ecg: + - id_col + - visit_col + - visitn_col + - measure_col + - value_col workflow: widget: safetyDeltaDelta links: diff --git a/inst/config/QTsafetyHistogram.yaml b/inst/config/QTsafetyHistogram.yaml index 9bc49e1..1afc550 100644 --- a/inst/config/QTsafetyHistogram.yaml +++ b/inst/config/QTsafetyHistogram.yaml @@ -4,6 +4,13 @@ type: htmlwidget package: safetyCharts domain: - ecg +dataSpec: + ecg: + - id_col + - measure_col + - value_col + - normal_col_low + - normal_col_high export: true order: -33 workflow: diff --git a/inst/config/QTsafetyOutlierExplorer.yaml b/inst/config/QTsafetyOutlierExplorer.yaml index 6d1ffbd..46fdf50 100644 --- a/inst/config/QTsafetyOutlierExplorer.yaml +++ b/inst/config/QTsafetyOutlierExplorer.yaml @@ -5,7 +5,23 @@ package: safetyCharts export: true order: -31 domain: + - dm - ecg +dataSpec: + dm: + - id_col + - age_col + - sex_col + - race_col + ecg: + - id_col + - visit_col + - visitn_col + - studyday_col + - measure_col + - value_col + - normal_col_low + - normal_col_high workflow: init: init_safetyOutlierExplorer widget: safetyOutlierExplorer diff --git a/inst/config/QTsafetyResultsOverTime.yaml b/inst/config/QTsafetyResultsOverTime.yaml index bfa4cbc..74fc716 100644 --- a/inst/config/QTsafetyResultsOverTime.yaml +++ b/inst/config/QTsafetyResultsOverTime.yaml @@ -6,6 +6,13 @@ export: true order: -34 domain: - ecg +dataSpec: + ecg: + - id_col + - visit_col + - visitn_col + - measure_col + - value_col workflow: init: init_safetyResultsOverTime widget: safetyResultsOverTime diff --git a/inst/config/QTsafetyShiftPlot.yaml b/inst/config/QTsafetyShiftPlot.yaml index 06789f3..4622604 100644 --- a/inst/config/QTsafetyShiftPlot.yaml +++ b/inst/config/QTsafetyShiftPlot.yaml @@ -6,6 +6,13 @@ export: true order: -35 domain: - ecg +dataSpec: + ecg: + - id_col + - visit_col + - visitn_col + - measure_col + - value_col workflow: init: init_safetyShiftPlot widget: safetyShiftPlot diff --git a/inst/config/aeExplorer.yaml b/inst/config/aeExplorer.yaml index c85c8a9..266e81e 100644 --- a/inst/config/aeExplorer.yaml +++ b/inst/config/aeExplorer.yaml @@ -5,8 +5,20 @@ package: safetyCharts export: true order: 2 domain: - - aes - dm + - aes +dataSpec: + dm: + - id_col + - treatment_col + aes: + - id_col + - term_col + - bodsys_col + - serious_col + - severity_col + - relationship_col + - outcome_col workflow: init: init_aeExplorer widget: aeExplorer diff --git a/inst/config/aeTimelines.yaml b/inst/config/aeTimelines.yaml index c1a3f99..1d9c40f 100644 --- a/inst/config/aeTimelines.yaml +++ b/inst/config/aeTimelines.yaml @@ -6,6 +6,15 @@ export: false order: 3 domain: - aes +dataSpec: + aes: + - id_col + - stdy_col + - endy_col + - seq_col + - term_col + - serious_col + - severity_col workflow: init: init_aeTimelines widget: aeTimelines diff --git a/inst/config/demogRTF.yaml b/inst/config/demogRTF.yaml index b37751b..53d1540 100644 --- a/inst/config/demogRTF.yaml +++ b/inst/config/demogRTF.yaml @@ -1,9 +1,17 @@ env: safetyGraphics label: Demographics Table type: module +export: false order: 1 domain: - dm +dataSpec: + dm: + - id_col + - treatment_col + - age_col + - sex_col + - race_col package: safetyCharts workflow: server: demogRTF_server diff --git a/inst/config/hepExplorer.yaml b/inst/config/hepExplorer.yaml index fd9f337..9c27af4 100644 --- a/inst/config/hepExplorer.yaml +++ b/inst/config/hepExplorer.yaml @@ -4,6 +4,16 @@ type: htmlwidget package: safetyCharts domain: - labs +dataSpec: + labs: + - id_col + - visit_col + - visitn_col + - studyday_col + - measure_col + - value_col + - normal_col_low + - normal_col_high export: true workflow: widget: hepExplorer diff --git a/inst/config/labdist.yaml b/inst/config/labdist.yaml index 2bad910..fcb84d1 100644 --- a/inst/config/labdist.yaml +++ b/inst/config/labdist.yaml @@ -4,6 +4,10 @@ type: module package: safetyCharts domain: - labs +dataSpec: + labs: + - measure_col + - value_col export: false order: -1 workflow: diff --git a/inst/config/paneledOutlierExplorer.yaml b/inst/config/paneledOutlierExplorer.yaml index a45d229..340d337 100644 --- a/inst/config/paneledOutlierExplorer.yaml +++ b/inst/config/paneledOutlierExplorer.yaml @@ -3,6 +3,16 @@ label: Paneled Outlier Explorer type: htmlwidget domain: - labs +dataSpec: + labs: + - id_col + - visit_col + - visitn_col + - studyday_col + - measure_col + - value_col + - normal_col_low + - normal_col_high package: safetyCharts export: true workflow: diff --git a/inst/config/safetyDeltaDelta.yaml b/inst/config/safetyDeltaDelta.yaml index 6bf2cf4..af4b40d 100644 --- a/inst/config/safetyDeltaDelta.yaml +++ b/inst/config/safetyDeltaDelta.yaml @@ -5,6 +5,13 @@ package: safetyCharts export: true domain: - labs +dataSpec: + labs: + - id_col + - visit_col + - visitn_col + - measure_col + - value_col workflow: widget: safetyDeltaDelta links: diff --git a/inst/config/safetyHistogram.yaml b/inst/config/safetyHistogram.yaml index 6dbe6f0..9a79cbb 100644 --- a/inst/config/safetyHistogram.yaml +++ b/inst/config/safetyHistogram.yaml @@ -4,6 +4,13 @@ type: htmlwidget package: safetyCharts domain: - labs +dataSpec: + labs: + - id_col + - measure_col + - value_col + - normal_col_low + - normal_col_high export: true workflow: widget: safetyHistogram diff --git a/inst/config/safetyOutlierExplorer.yaml b/inst/config/safetyOutlierExplorer.yaml index aa7f6f0..6e615e4 100644 --- a/inst/config/safetyOutlierExplorer.yaml +++ b/inst/config/safetyOutlierExplorer.yaml @@ -4,7 +4,23 @@ type: htmlwidget package: safetyCharts export: true domain: + - dm - labs +dataSpec: + dm: + - id_col + - age_col + - sex_col + - race_col + labs: + - id_col + - visit_col + - visitn_col + - studyday_col + - measure_col + - value_col + - normal_col_low + - normal_col_high workflow: init: init_safetyOutlierExplorer widget: safetyOutlierExplorer diff --git a/inst/config/safetyOutlierExplorerModule.yaml b/inst/config/safetyOutlierExplorerModule.yaml index eb28ec5..6c0645a 100644 --- a/inst/config/safetyOutlierExplorerModule.yaml +++ b/inst/config/safetyOutlierExplorerModule.yaml @@ -6,6 +6,12 @@ export: false order: -1 domain: - labs +dataSpec: + labs: + - id_col + - studyday_col + - measure_col + - value_col workflow: ui: safetyOutlierExplorer_ui server: safetyOutlierExplorer_server diff --git a/inst/config/safetyOutlierExplorerStatic.yaml b/inst/config/safetyOutlierExplorerStatic.yaml index 7cec032..2541855 100644 --- a/inst/config/safetyOutlierExplorerStatic.yaml +++ b/inst/config/safetyOutlierExplorerStatic.yaml @@ -6,6 +6,12 @@ export: true order: -1 domain: - labs +dataSpec: + labs: + - id_col + - studyday_col + - measure_col + - value_col workflow: main: safety_outlier_explorer links: diff --git a/inst/config/safetyResultsOverTime.yaml b/inst/config/safetyResultsOverTime.yaml index 61bfa47..5a07bd1 100644 --- a/inst/config/safetyResultsOverTime.yaml +++ b/inst/config/safetyResultsOverTime.yaml @@ -5,6 +5,13 @@ package: safetyCharts export: true domain: - labs +dataSpec: + labs: + - id_col + - visit_col + - visitn_col + - measure_col + - value_col workflow: init: init_safetyResultsOverTime widget: safetyResultsOverTime diff --git a/inst/config/safetyResultsOverTimeStatic.yaml b/inst/config/safetyResultsOverTimeStatic.yaml index 35e09d4..e482ee2 100644 --- a/inst/config/safetyResultsOverTimeStatic.yaml +++ b/inst/config/safetyResultsOverTimeStatic.yaml @@ -6,6 +6,13 @@ export: true order: -1 domain: - labs +dataSpec: + labs: + - visit_col + - visitn_col + - measure_col + - value_col + - group_col workflow: main: safety_results_over_time links: diff --git a/inst/config/safetyShiftPlot.yaml b/inst/config/safetyShiftPlot.yaml index 18fb531..bcd6339 100644 --- a/inst/config/safetyShiftPlot.yaml +++ b/inst/config/safetyShiftPlot.yaml @@ -5,6 +5,13 @@ package: safetyCharts export: true domain: - labs +dataSpec: + labs: + - id_col + - visit_col + - visitn_col + - measure_col + - value_col workflow: init: init_safetyShiftPlot widget: safetyShiftPlot diff --git a/inst/config/tendril.yaml b/inst/config/tendril.yaml index 2bfb7d9..46feb6f 100644 --- a/inst/config/tendril.yaml +++ b/inst/config/tendril.yaml @@ -5,8 +5,17 @@ package: safetyCharts export: true order: 4 domain: - - aes - dm + - aes +dataSpec: + dm: + - id_col + - treatment_col + aes: + - id_col + - stdy_col + - endy_col + - bodsys_col workflow: main: tendril_chart links: diff --git a/tests/testthat/test_check_config.R b/tests/testthat/test_check_config.R new file mode 100644 index 0000000..52e4c65 --- /dev/null +++ b/tests/testthat/test_check_config.R @@ -0,0 +1,39 @@ +configurations <- system.file('config', package = 'safetyCharts') %>% + list.files(full.names = TRUE) %>% + purrr::map(~yaml::read_yaml(.x)) + +test_that('Chart configurations include all required properties.', { + expected_properties <- c( + 'dataSpec', + 'domain', + 'env', + 'export', + 'label', + 'links', + #'order', + 'package', + 'type', + 'workflow' + ) + + for (i in seq_along(configurations)) { + configuration <- configurations[[ i ]] + actual_properties <- names(configuration) %>% sort() + missing_properties <- setdiff(expected_properties, actual_properties) + + expect_true( + length(missing_properties) == 0 + ) + } +}) + +test_that('Chart configuration domains match domains in data specification.', { + for (i in seq_along(configurations)) { + configuration <- configurations[[ i ]] + + expect_equal( + configuration$domain %>% sort(), + names(configuration$dataSpec) %>% sort() + ) + } +}) From cf73c615ad4e433b0e1b28bd09bb4d55ec201fb5 Mon Sep 17 00:00:00 2001 From: Jeremy Wildfire Date: Thu, 30 Mar 2023 10:45:17 -0400 Subject: [PATCH 22/50] add medical history --- DESCRIPTION | 2 +- NAMESPACE | 3 ++- R/init_cmExplorer.R | 4 ++-- R/init_mhExplorer.R | 42 ++++++++++++++++++++++++++++++++++++ data-raw/makeMeta.R | 4 ++++ data-raw/meta_mh.csv | 7 ++++++ data/meta_mh.rda | Bin 0 -> 530 bytes inst/config/mhExplorer.yaml | 18 ++++++++++++++++ man/hepExplorer.Rd | 6 +++--- man/init_aeExplorer.Rd | 2 +- man/init_aeTimelines.Rd | 2 +- man/init_cmExplorer.Rd | 6 +++--- man/init_mhExplorer.Rd | 19 ++++++++++++++++ 13 files changed, 103 insertions(+), 12 deletions(-) create mode 100644 R/init_mhExplorer.R create mode 100644 data-raw/meta_mh.csv create mode 100644 data/meta_mh.rda create mode 100644 inst/config/mhExplorer.yaml create mode 100644 man/init_mhExplorer.Rd diff --git a/DESCRIPTION b/DESCRIPTION index 2e526aa..30ca381 100644 --- a/DESCRIPTION +++ b/DESCRIPTION @@ -15,7 +15,7 @@ BugReports: https://github.com/SafetyGraphics/safetyCharts/issues License: MIT + file LICENSE Encoding: UTF-8 LazyData: true -RoxygenNote: 7.2.2 +RoxygenNote: 7.2.3 Roxygen: list(markdown = TRUE) Imports: dplyr, diff --git a/NAMESPACE b/NAMESPACE index f1a5d31..9fc2b4f 100644 --- a/NAMESPACE +++ b/NAMESPACE @@ -9,8 +9,9 @@ export(demogRTF_table) export(demogRTF_ui) export(hepExplorer) export(init_aeExplorer) -export(init_cmExplorer) export(init_aeTimelines) +export(init_cmExplorer) +export(init_mhExplorer) export(init_paneledOutlierExplorer) export(init_safetyOutlierExplorer) export(init_safetyResultsOverTime) diff --git a/R/init_cmExplorer.R b/R/init_cmExplorer.R index cbe28b2..022134f 100644 --- a/R/init_cmExplorer.R +++ b/R/init_cmExplorer.R @@ -1,6 +1,6 @@ -#' Initialize Settings for Adverse Event Explorer widget +#' Initialize Settings for Conmeds Explorer widget #' -#' @param data labs data structured as one record per person per visit per measurement. See details for column requirements. +#' @param data Con meds and demographics data. See details for column requirements. #' @param settings named list of settings #' #' @return returns list with data and settings diff --git a/R/init_mhExplorer.R b/R/init_mhExplorer.R new file mode 100644 index 0000000..3f845fc --- /dev/null +++ b/R/init_mhExplorer.R @@ -0,0 +1,42 @@ +#' Initialize Settings for Medical History Explorer widget +#' +#' @param data medical history and demographics data. +#' @param settings named list of settings +#' +#' @return returns list with data and settings +#' +#' @export + + +init_mhExplorer <- function(data, settings) { + print("MH TIME") + # Merge treatment with adverse events. + dm_sub <- data$dm %>% select(settings[["dm"]][["id_col"]], settings[["dm"]][["treatment_col"]]) + anly <- dm_sub %>% left_join(data$mh) # left join to keep all rows in dm (even if there were no AEs) + + settings <- c(settings$mh, settings$labs) + + settings$variables <- list( + major = settings[["class_col"]], + minor = settings[["code_col"]], + group = settings[["trt_col"]], + id = paste0(settings[["id_col"]]), + filters = list(), + details = list() + ) + + settings$variableOptions <- list( + group = c( + settings[["treatment_values--group1"]], + settings[["treatment_values--group2"]] + ) + ) + + settings$defaults <- list( + placeholderFlag = list( + valueCol = settings[["class_col"]], + values = c("", NA, NULL) + ) + ) + return(list(data = anly, settings = settings)) +} diff --git a/data-raw/makeMeta.R b/data-raw/makeMeta.R index 51cd4a7..53448cd 100644 --- a/data-raw/makeMeta.R +++ b/data-raw/makeMeta.R @@ -25,6 +25,10 @@ usethis::use_data(meta_cm, overwrite = TRUE) meta_dm<-read_csv("data-raw/meta_dm.csv")[] usethis::use_data(meta_dm, overwrite = TRUE) +#mh +meta_mh<-read_csv("data-raw/meta_mh.csv")[] +usethis::use_data(meta_mh, overwrite = TRUE) + #hepExplorer meta_hepExplorer<-read_csv("data-raw/meta_hepExplorer.csv")[] usethis::use_data(meta_hepExplorer, overwrite = TRUE) diff --git a/data-raw/meta_mh.csv b/data-raw/meta_mh.csv new file mode 100644 index 0000000..2f75fa9 --- /dev/null +++ b/data-raw/meta_mh.csv @@ -0,0 +1,7 @@ +text_key,domain,col_key,field_key,type,label,description,multiple,standard_adam,standard_sdtm +id_col,mh,id_col,,column,ID column,Unique subject identifier variable name.,FALSE,,USUBJID +seq_col,mh,seq_col,,column,Sequence column,Event sequence number variable name,FALSE,,MHSEQ +stdy_col,mh,dy_col,,column,MH Day column,Event start day variable name,FALSE,,MHDY +code_col,mh,code_col,,column,MH Code Column,Dictionary-derived low-level code,FALSE,,MHTERM +class_col,mh,class_col,,column,MH Class System,Dictionary-derived high-level class,FALSE,,MHBODSYS +sev_col,mh,severity_col,,column,MH Severity,Severity,FALSE,,MHSEV \ No newline at end of file diff --git a/data/meta_mh.rda b/data/meta_mh.rda new file mode 100644 index 0000000000000000000000000000000000000000..d3c632e2781fd905b586e905e3fa58847ce1f138 GIT binary patch literal 530 zcmV+t0`2`mT4*^jL0KkKS!1!8+W-M~f589$$bx7?5C9%>zhJ-r|KLCX01?0e+$Eq5 zQ%q3PMu2Dl8fZO3L5)p4AR06Vq|;MP2dHeJ>IO{=fY1S>LqkJAa{^*$FqtxB$iiTn zX_1M5A%IAc8Y+H`Dd~i0#A;|X(?d-e0jH=9lz0@FT{7WcjxA|bB%l-wLE-evRKxPb z=klk0m0d($Bjdg%lC}N!$GxE>c-ShDlk3-iPiGb<-H{g4G#Fg#n)hacZ#{5XNXW|W zlqg*^i^E0WTRL0geb(b?9AX;`LjD#=?f=F^O0^;naje3e{ z<&q-iV?O>x5U^!f1#5|vr-U%O0MNppBh8C$G|ixP(-i&e1LtyIg$OV!pr|?{qEaRL zTYGBucA|ugDkNBm;(jYPP?Djqhsr$#;H+H)F%Xo6f=UomoGF<=o7`ZebD*_;Qz))I zE=81M33$)zF4jegMv@!Ta^}zHkzm+y+>0cQ za#76KJlV_M>e1FuJ{Z3SqkWh#t-Bz)oYt9hW?hzgmaAwZ4mDv1P}Y&`8sIXLynP!) UWjX)S82{q#NT&)C40ba+VA~t;!2kdN literal 0 HcmV?d00001 diff --git a/inst/config/mhExplorer.yaml b/inst/config/mhExplorer.yaml new file mode 100644 index 0000000..07c1ea6 --- /dev/null +++ b/inst/config/mhExplorer.yaml @@ -0,0 +1,18 @@ +env: safetyGraphics +label: Medical History Explorer +type: htmlwidget +package: safetyCharts +export: true +order: 2 +domain: + - mh + - dm +workflow: + init: init_mhExplorer + widget: aeExplorer +links: + Homepage: https://github.com/RhoInc/aeexplorer + Wiki: https://github.com/RhoInc/aeexplorer/wiki + Issues: https://github.com/RhoInc/aeexplorer/issues + Demo: https://rhoinc.github.io/aeexplorer/test-page/ + safetyCharts: https://github.com/SafetyGraphics/safetycharts diff --git a/man/hepExplorer.Rd b/man/hepExplorer.Rd index f48f8e5..e1aa6b3 100644 --- a/man/hepExplorer.Rd +++ b/man/hepExplorer.Rd @@ -4,10 +4,10 @@ \alias{hepExplorer} \title{Make standalone hepExplorer html widget} \usage{ -hepExplorer(df = safetyData::adam_adlbc, mapping = NULL, ...) +hepExplorer(data = safetyData::adam_adlbc, mapping = NULL, ...) } \arguments{ -\item{df}{data frame containing lab data used to render for hepExplorer. Default is safetyData::adam_adlbc.} +\item{data}{data frame containing lab data used to render for hepExplorer. Default is safetyData::adam_adlbc.} \item{mapping}{named list with the current data mappings. See details for default mapping.} @@ -63,7 +63,7 @@ hepExplorer(y_options='all') # Use custom mapping for SDTM data hepExplorer( - df=safetyData::sdtm_lb, + data=safetyData::sdtm_lb, measure_col = "LBTEST", measure_values = list( ALT = "Alanine Aminotransferase", diff --git a/man/init_aeExplorer.Rd b/man/init_aeExplorer.Rd index 624e442..1ca3dab 100644 --- a/man/init_aeExplorer.Rd +++ b/man/init_aeExplorer.Rd @@ -7,7 +7,7 @@ init_aeExplorer(data, settings) } \arguments{ -\item{data}{labs data structured as one record per person per visit per measurement. See details for column requirements.} +\item{data}{adverse events data structured as one record per event. See details for column requirements.} \item{settings}{named list of settings} } diff --git a/man/init_aeTimelines.Rd b/man/init_aeTimelines.Rd index 4b035e9..3e965cf 100644 --- a/man/init_aeTimelines.Rd +++ b/man/init_aeTimelines.Rd @@ -7,7 +7,7 @@ init_aeTimelines(data, settings) } \arguments{ -\item{data}{labs data structured as one record per person per visit per measurement. See details for column requirements.} +\item{data}{adverse events data structured as one record per event. See details for column requirements.} \item{settings}{named list of settings} } diff --git a/man/init_cmExplorer.Rd b/man/init_cmExplorer.Rd index 3b71083..860d106 100644 --- a/man/init_cmExplorer.Rd +++ b/man/init_cmExplorer.Rd @@ -2,12 +2,12 @@ % Please edit documentation in R/init_cmExplorer.R \name{init_cmExplorer} \alias{init_cmExplorer} -\title{Initialize Settings for Adverse Event Explorer widget} +\title{Initialize Settings for Conmeds Explorer widget} \usage{ init_cmExplorer(data, settings) } \arguments{ -\item{data}{labs data structured as one record per person per visit per measurement. See details for column requirements.} +\item{data}{Con meds and demographics data. See details for column requirements.} \item{settings}{named list of settings} } @@ -15,5 +15,5 @@ init_cmExplorer(data, settings) returns list with data and settings } \description{ -Initialize Settings for Adverse Event Explorer widget +Initialize Settings for Conmeds Explorer widget } diff --git a/man/init_mhExplorer.Rd b/man/init_mhExplorer.Rd new file mode 100644 index 0000000..e3d9fea --- /dev/null +++ b/man/init_mhExplorer.Rd @@ -0,0 +1,19 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/init_mhExplorer.R +\name{init_mhExplorer} +\alias{init_mhExplorer} +\title{Initialize Settings for Medical History Explorer widget} +\usage{ +init_mhExplorer(data, settings) +} +\arguments{ +\item{data}{medical history and demographics data.} + +\item{settings}{named list of settings} +} +\value{ +returns list with data and settings +} +\description{ +Initialize Settings for Medical History Explorer widget +} From 47cd0ba6fd5d73f4087d18c4013894078f9d2b7c Mon Sep 17 00:00:00 2001 From: Jeremy Wildfire Date: Thu, 30 Mar 2023 17:50:44 -0400 Subject: [PATCH 23/50] remove optional columns --- inst/config/aeExplorer.yaml | 4 ---- 1 file changed, 4 deletions(-) diff --git a/inst/config/aeExplorer.yaml b/inst/config/aeExplorer.yaml index 266e81e..49b7007 100644 --- a/inst/config/aeExplorer.yaml +++ b/inst/config/aeExplorer.yaml @@ -15,10 +15,6 @@ dataSpec: - id_col - term_col - bodsys_col - - serious_col - - severity_col - - relationship_col - - outcome_col workflow: init: init_aeExplorer widget: aeExplorer From 39e5086511fef87323b94a8668b97dbf49828d0e Mon Sep 17 00:00:00 2001 From: Jeremy Wildfire Date: Thu, 30 Mar 2023 17:54:57 -0400 Subject: [PATCH 24/50] add required columns --- inst/config/cmExplorer.yaml | 9 +++++++-- inst/config/mhExplorer.yaml | 10 ++++++++-- 2 files changed, 15 insertions(+), 4 deletions(-) diff --git a/inst/config/cmExplorer.yaml b/inst/config/cmExplorer.yaml index 0c7281a..1041069 100644 --- a/inst/config/cmExplorer.yaml +++ b/inst/config/cmExplorer.yaml @@ -5,8 +5,13 @@ package: safetyCharts export: true order: 2 domain: - - cm - - dm + dm: + - id_col + - treatment_col + cm: + - id_col + - class_col + - code_col workflow: init: init_cmExplorer widget: aeExplorer diff --git a/inst/config/mhExplorer.yaml b/inst/config/mhExplorer.yaml index 07c1ea6..5adbb81 100644 --- a/inst/config/mhExplorer.yaml +++ b/inst/config/mhExplorer.yaml @@ -5,8 +5,14 @@ package: safetyCharts export: true order: 2 domain: - - mh - - dm +domain: + dm: + - id_col + - treatment_col + mh: + - id_col + - class_col + - code_col workflow: init: init_mhExplorer widget: aeExplorer From b5a87869c250acb80d45d6cd18b07dd11a38eee7 Mon Sep 17 00:00:00 2001 From: Jeremy Wildfire Date: Thu, 30 Mar 2023 17:59:03 -0400 Subject: [PATCH 25/50] fix typo + remove cm timeline --- inst/config/cmTimelines.yaml | 17 ----------------- inst/config/mhExplorer.yaml | 1 - 2 files changed, 18 deletions(-) delete mode 100644 inst/config/cmTimelines.yaml diff --git a/inst/config/cmTimelines.yaml b/inst/config/cmTimelines.yaml deleted file mode 100644 index ae8517f..0000000 --- a/inst/config/cmTimelines.yaml +++ /dev/null @@ -1,17 +0,0 @@ -env: safetyGraphics -label: Com Meds Timelines -type: htmlwidget -package: safetyCharts -export: false -order: 3 -domain: - - cm -workflow: - widget: aeTimelines -links: - Homepage: https://github.com/RhoInc/ae-timelines - Wiki: https://github.com/RhoInc/ae-timelines/wiki - Issues: https://github.com/RhoInc/ae-timelines/issues - Demo: https://rhoinc.github.io/ae-timelines/test-page/ - safetyCharts: https://github.com/SafetyGraphics/safetycharts - diff --git a/inst/config/mhExplorer.yaml b/inst/config/mhExplorer.yaml index 5adbb81..69a09d7 100644 --- a/inst/config/mhExplorer.yaml +++ b/inst/config/mhExplorer.yaml @@ -4,7 +4,6 @@ type: htmlwidget package: safetyCharts export: true order: 2 -domain: domain: dm: - id_col From 820b2c688063a62066253f5254be01c961e355f5 Mon Sep 17 00:00:00 2001 From: Jeremy Wildfire Date: Wed, 19 Apr 2023 09:27:29 -0400 Subject: [PATCH 26/50] add vitals. fix #124 --- R/meta.R | 61 ++++++++++++++++++++++++++ data-raw/makeMeta.R | 4 ++ data-raw/meta_vitals.csv | 8 ++++ data/meta_vitals.rda | Bin 0 -> 534 bytes inst/config/safetyVitalsOverTime.yaml | 23 ++++++++++ man/meta_cm.Rd | 31 +++++++++++++ man/meta_mh.Rd | 31 +++++++++++++ man/meta_vitals.Rd | 31 +++++++++++++ 8 files changed, 189 insertions(+) create mode 100644 data-raw/meta_vitals.csv create mode 100644 data/meta_vitals.rda create mode 100644 inst/config/safetyVitalsOverTime.yaml create mode 100644 man/meta_cm.Rd create mode 100644 man/meta_mh.Rd create mode 100644 man/meta_vitals.Rd diff --git a/R/meta.R b/R/meta.R index 40101f1..5f2a7e0 100644 --- a/R/meta.R +++ b/R/meta.R @@ -38,6 +38,26 @@ "meta_labs" +#' Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the vital signs domain. One record per unique data mapping +#' +#' @format A data frame with X rows and 10 columns +#' \describe{ +#' \item{domain}{Data domain} +#' \item{text_key}{Text key indicating the setting name. \code{'--'} delimiter indicates a field level data mapping} +#' \item{col_key}{Key for the column mapping} +#' \item{field_key}{Key for the field mapping (if any)} +#' \item{type}{type of mapping - "field" or "column"} +#' \item{label}{Label} +#' \item{description}{Description} +#' \item{multiple}{Mapping supports multiple columns/fields } +#' \item{standard_adam}{Default values for the ADaM data standard} +#' \item{standard_sdtm}{Default values for the SDTM data standard} +#' } +#' +#' @source Created for this package + +"meta_vitals" + #' Metadata data frame containing information about the data mapping used to configure safetyGraphics charts for the dm domain. One record per unique data mapping #' @@ -99,3 +119,44 @@ #' @source Created for this package "meta_hepExplorer" + + +#' Metadata data frame containing information about the data mapping used to configure safetyGraphics for the Concomitant medications Domain. One record per unique data mapping +#' +#' @format A data frame with X rows and 10 columns +#' \describe{ +#' \item{domain}{Data domain} +#' \item{text_key}{Text key indicating the setting name. \code{'--'} delimiter indicates a field level data mapping} +#' \item{col_key}{Key for the column mapping} +#' \item{field_key}{Key for the field mapping (if any)} +#' \item{type}{type of mapping - "field" or "column"} +#' \item{label}{Label} +#' \item{description}{Description} +#' \item{multiple}{Mapping supports multiple columns/fields } +#' \item{standard_adam}{Default values for the ADaM data standard} +#' \item{standard_sdtm}{Default values for the SDTM data standard} +#' } +#' +#' @source Created for this package + +"meta_cm" + +#' Metadata data frame containing information about the data mapping used to configure safetyGraphics for the Medical History Domain. One record per unique data mapping +#' +#' @format A data frame with X rows and 10 columns +#' \describe{ +#' \item{domain}{Data domain} +#' \item{text_key}{Text key indicating the setting name. \code{'--'} delimiter indicates a field level data mapping} +#' \item{col_key}{Key for the column mapping} +#' \item{field_key}{Key for the field mapping (if any)} +#' \item{type}{type of mapping - "field" or "column"} +#' \item{label}{Label} +#' \item{description}{Description} +#' \item{multiple}{Mapping supports multiple columns/fields } +#' \item{standard_adam}{Default values for the ADaM data standard} +#' \item{standard_sdtm}{Default values for the SDTM data standard} +#' } +#' +#' @source Created for this package + +"meta_mh" diff --git a/data-raw/makeMeta.R b/data-raw/makeMeta.R index 53448cd..3501bf7 100644 --- a/data-raw/makeMeta.R +++ b/data-raw/makeMeta.R @@ -13,6 +13,10 @@ usethis::use_data(meta_ecg, overwrite = TRUE) meta_labs<-read_csv("data-raw/meta_labs.csv")[] usethis::use_data(meta_labs, overwrite = TRUE) +#vitals +meta_vitals<-read_csv("data-raw/meta_vitals.csv")[] +usethis::use_data(meta_vitals, overwrite = TRUE) + #aes meta_aes<-read_csv("data-raw/meta_aes.csv")[] usethis::use_data(meta_aes, overwrite = TRUE) diff --git a/data-raw/meta_vitals.csv b/data-raw/meta_vitals.csv new file mode 100644 index 0000000..f1653d5 --- /dev/null +++ b/data-raw/meta_vitals.csv @@ -0,0 +1,8 @@ +text_key,domain,col_key,field_key,type,label,description,multiple,standard_adam,standard_sdtm +id_col,vitals,id_col,,column,ID column,Unique subject identifier variable name.,FALSE,USUBJID,USUBJID +value_col,vitals,value_col,,column,Value column,Vitals result variable name.,FALSE,AVAL,VSSTRESN +measure_col,vitals,measure_col,,column,Measure column,Vitals measure variable name,FALSE,PARAM,VSTEST +studyday_col,vitals,studyday_col,,column,Study Day column,Visit day variable name,FALSE,ADY,VSDY +visit_col,vitals,visit_col,,column,Visit column,Visit variable name,FALSE,VISIT,VISIT +visitn_col,vitals,visitn_col,,column,Visit Number column,Visit number variable name,FALSE,VISITNUM,VISITNUM +unit_col,vitals,unit_col,,column,Unit column,Unit of measure variable name,FALSE,,VSSTRESU \ No newline at end of file diff --git a/data/meta_vitals.rda b/data/meta_vitals.rda new file mode 100644 index 0000000000000000000000000000000000000000..a398769a7e77317c6df32caf1d71a07240878c10 GIT binary patch literal 534 zcmV+x0_puiT4*^jL0KkKS!>Xh6#xOJ|G@wMNS;7J5CAqeUtqsK|KLCX03pBu^-6$* zl4(e2Z4v4;Gz|dsK*-*ywy0<{JwYTw4Ft-YPeN*WA)%q6=>sRI0p!#| z!eKB&OieI3fJ_9)zzD>|!eKB&OieK1%DDxy&5h*P5|jXR?2_vE_w&&pU#3h`DgB7r zL$F;HyCD!QG3{nY5<!*~?qbbSo zw9i$6Kz&N4&GL<8_fgpryMud-)eke>2@Jy{)^!ujJCqVHu`f)`p0}ChjcBOKK*l*x zdBx!jPCvq5kEBF-JPNGbz(|1gm}&dX3ecjjd71h-~e$B36<{gE~xgm~XJK?grlI YF?&F Date: Wed, 19 Apr 2023 09:36:02 -0400 Subject: [PATCH 27/50] get cmTimelines working --- R/init_cmExplorer.R | 17 +++++++++++------ R/init_cmTimelines.R | 19 +++++++++++++++++++ data-raw/meta_cm.csv | 13 +++++++------ data/meta_aes.rda | Bin 591 -> 600 bytes data/meta_cm.rda | Bin 527 -> 553 bytes data/meta_dm.rda | Bin 485 -> 487 bytes data/meta_ecg.rda | Bin 1128 -> 1139 bytes data/meta_hepExplorer.rda | Bin 539 -> 537 bytes data/meta_labs.rda | Bin 626 -> 619 bytes inst/config/cmExplorer.yaml | 10 +++++++++- inst/config/cmTimelines.yaml | 9 +++++++++ 11 files changed, 55 insertions(+), 13 deletions(-) create mode 100644 R/init_cmTimelines.R diff --git a/R/init_cmExplorer.R b/R/init_cmExplorer.R index cbe28b2..07ab065 100644 --- a/R/init_cmExplorer.R +++ b/R/init_cmExplorer.R @@ -1,18 +1,23 @@ -#' Initialize Settings for Adverse Event Explorer widget +#' Initialize Settings for Concomitant Medication Explorer widget #' -#' @param data labs data structured as one record per person per visit per measurement. See details for column requirements. +#' @param data concomitant medication data structured as one record per person per visit per +#' measurement. See details for column requirements. #' @param settings named list of settings #' #' @return returns list with data and settings #' #' @export - init_cmExplorer <- function(data, settings) { - print("CM TIME") # Merge treatment with adverse events. - dm_sub <- data$dm %>% select(settings[["dm"]][["id_col"]], settings[["dm"]][["treatment_col"]]) - anly <- dm_sub %>% left_join(data$cm) # left join to keep all rows in dm (even if there were no AEs) + dm_sub <- data$dm %>% + select( + settings[["dm"]][["id_col"]], + settings[["dm"]][["treatment_col"]] + ) + + # left join to keep all rows in dm (even if there were no CMs) + anly <- dm_sub %>% left_join(data$cm) settings <- c(settings$cm, settings$labs) diff --git a/R/init_cmTimelines.R b/R/init_cmTimelines.R new file mode 100644 index 0000000..4baf03d --- /dev/null +++ b/R/init_cmTimelines.R @@ -0,0 +1,19 @@ +#' Initialize Settings for CM Timeline widget +#' +#' @param data concomitant medication data structured as one record per event. See details for +#' column requirements. +#' @param settings named list of settings +#' +#' @return returns list with data and settings +#' +#' @export + +init_cmTimelines <- function(data, settings) { + settings$color <- list( + value_col = settings[["indication_col"]] + ) + data$AESER <- NA + #settings$highlight <- NULL + + return(list(data = data, settings = settings)) +} diff --git a/data-raw/meta_cm.csv b/data-raw/meta_cm.csv index 74c0c56..20e4db0 100644 --- a/data-raw/meta_cm.csv +++ b/data-raw/meta_cm.csv @@ -1,7 +1,8 @@ text_key,domain,col_key,field_key,type,label,description,multiple,standard_adam,standard_sdtm -id_col,cm,id_col,,column,ID column,Unique subject identifier variable name.,FALSE,,USUBJID -seq_col,cm,seq_col,,column,Sequence column,Event sequence number variable name,FALSE,,CMSEQ -stdy_col,cm,stdy_col,,column,CM Start day column,Event start day variable name,FALSE,,CMSTDY -endy_col,cm,endy_col,,column,CM End day column,Event end day variable name,FALSE,,CMENDY 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package: safetyCharts export: true order: 2 domain: - - cm - dm + - cm +dataSpec: + dm: + - id_col + - treatment_col + cm: + - id_col + - code_col + - class_col workflow: init: init_cmExplorer widget: aeExplorer diff --git a/inst/config/cmTimelines.yaml b/inst/config/cmTimelines.yaml index ae8517f..2632771 100644 --- a/inst/config/cmTimelines.yaml +++ b/inst/config/cmTimelines.yaml @@ -6,7 +6,16 @@ export: false order: 3 domain: - cm +dataSpec: + cm: + - id_col + - stdy_col + - endy_col + - seq_col + - code_col + - indication_col workflow: + init: init_cmTimelines widget: aeTimelines links: Homepage: https://github.com/RhoInc/ae-timelines From 576cb20d436c9b21ac934d68ab58e4ad4304feed Mon Sep 17 00:00:00 2001 From: Jeremy Wildfire Date: Wed, 19 Apr 2023 09:51:31 -0400 Subject: [PATCH 28/50] add exposure domain. fix #136 --- R/meta.R | 20 ++++++++++++++++++++ data-raw/makeMeta.R | 8 +++++++- data-raw/meta_ex.csv | 9 +++++++++ data/meta_ex.rda | Bin 0 -> 549 bytes man/meta_ex.Rd | 31 +++++++++++++++++++++++++++++++ 5 files changed, 67 insertions(+), 1 deletion(-) create mode 100644 data-raw/meta_ex.csv create mode 100644 data/meta_ex.rda create mode 100644 man/meta_ex.Rd diff --git a/R/meta.R b/R/meta.R index 5f2a7e0..7177449 100644 --- a/R/meta.R +++ b/R/meta.R @@ -160,3 +160,23 @@ #' @source Created for this package "meta_mh" + +#' Metadata data frame containing information about the data mapping used to configure safetyGraphics for the Exposure Domain. One record per unique data mapping +#' +#' @format A data frame with X rows and 10 columns +#' \describe{ +#' \item{domain}{Data domain} +#' \item{text_key}{Text key indicating the setting name. \code{'--'} delimiter indicates a field level data mapping} +#' \item{col_key}{Key for the column mapping} +#' \item{field_key}{Key for the field mapping (if any)} +#' \item{type}{type of mapping - "field" or "column"} +#' \item{label}{Label} +#' \item{description}{Description} +#' \item{multiple}{Mapping supports multiple columns/fields } +#' \item{standard_adam}{Default values for the ADaM data standard} +#' \item{standard_sdtm}{Default values for the SDTM data standard} +#' } +#' +#' @source Created for this package + +"meta_ex" \ No newline at end of file diff --git a/data-raw/makeMeta.R b/data-raw/makeMeta.R index 3501bf7..fdb2c16 100644 --- a/data-raw/makeMeta.R +++ b/data-raw/makeMeta.R @@ -2,7 +2,7 @@ library(tidyverse) library(usethis) - # brackets after read_csv to remove spec_tbl_df class per https://www.tidyverse.org/blog/2018/12/readr-1-3-1/ +# brackets after read_csv to remove spec_tbl_df class per https://www.tidyverse.org/blog/2018/12/readr-1-3-1/ #Copy metadata to /data #ecg @@ -33,6 +33,12 @@ usethis::use_data(meta_dm, overwrite = TRUE) meta_mh<-read_csv("data-raw/meta_mh.csv")[] usethis::use_data(meta_mh, overwrite = TRUE) +#ex +meta_ex<-read_csv("data-raw/meta_ex.csv")[] +usethis::use_data(meta_ex, overwrite = TRUE) + + +#Chart-level metadata #hepExplorer meta_hepExplorer<-read_csv("data-raw/meta_hepExplorer.csv")[] usethis::use_data(meta_hepExplorer, overwrite = TRUE) diff --git a/data-raw/meta_ex.csv b/data-raw/meta_ex.csv new file mode 100644 index 0000000..908ca93 --- /dev/null +++ b/data-raw/meta_ex.csv @@ -0,0 +1,9 @@ +text_key,domain,col_key,field_key,type,label,description,multiple,standard_adam,standard_sdtm +id_col,ex,id_col,,column,ID column,Unique subject identifier variable name.,FALSE,,USUBJID +seq_col,ex,seq_col,,column,Sequence column,Event sequence number variable name,FALSE,,EXSEQ +stdy_col,ex,stdy_col,,column,Ex Start day column,Event start day variable name,FALSE,,EXSTDY +endy_col,ex,endy_col,,column,Ex End day column,Event end day variable name,FALSE,,EXENDY +treatment_col,ex,treatment_col,,column,Ex Treatment Column,Treatment,FALSE,,EXTRT +dose_col,ex,dose_col,,column,Ex Dose System,Dose,FALSE,,EXDOSE +visit_col,ex,visit_col,,column,Visit Column,Visit,FALSE,,VISIT +visitn_col,ex,visitn_col,,column,Visit Number Column,Visit Number,FALSE,,VISITN \ No newline at end of file diff --git a/data/meta_ex.rda b/data/meta_ex.rda new file mode 100644 index 0000000000000000000000000000000000000000..da5a1ef9065f6f473868e1e3fa9b627969950654 GIT binary patch literal 549 zcmV+=0^0pTT4*^jL0KkKStzLV`~U&Af589$=nBX|5C9%AzhJ*V|KLCX071Y3`K)(t z=7ge}X(y8u@@h6j4^u|e8Z`AZ^$!&EngAM_5Ndi%Mw)topa1{>0B8hKQ_6;(qts{v z)EWR903M*w2dEN=lM(4Blr~K=jT&M!#K0hFh&Ge(zc8w0Kv#lS;8vHGKuCedZk;AR z&@n%}pHg%hpsZgTr8Eqv$8@nmDCfYmT^~=Yv0KrdP>X7Ho--M0Ao(H20~~`BF~-^k ziS~|w=rRUZWQYR}+6X`^2?)zBKnU9hG#xOlAczSRN_WZy7A2n}72E|zAfm8%#4`Wb z?yWq=TTdQWu6cDDm0j6on=J4x*LewSozWbwR_*gnEf&6JY%26^chc%JEyoRWOoEzq zid0m6nnnyOspnYZgPVhIlXYVg5YnJw3tS2oAxfVb5S?xSnouVV(LhHb8y1lppf}y+ z?+-u}CnM?KAdhGOqDn*{ODqd;Lo_Hc6rUN)up|u{zOyPMKZxBJu#_^AZXeF0Xx0-3 zKr}En11L72lwq=aGz&5n&82sy$tDnCyspKFO#=jgv=ekVzOf2qP#=&$sZkX{X|sf3 za|6U8sFb+ONH86BgY+pxp*hnK5L7mDHeG#HB^-@Gh7ZLV(7SXvkv~mTKoF9bzuKJs n#yAlZfGJGoLWxiw1qi}G?3;LrDUX{)7yMnx6yZWZqNCIBMT+6H literal 0 HcmV?d00001 diff --git a/man/meta_ex.Rd b/man/meta_ex.Rd new file mode 100644 index 0000000..94619ae --- /dev/null +++ b/man/meta_ex.Rd @@ -0,0 +1,31 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/meta.R +\docType{data} +\name{meta_ex} +\alias{meta_ex} +\title{Metadata data frame containing information about the data mapping used to configure safetyGraphics for the Exposure Domain. One record per unique data mapping} +\format{ +A data frame with X rows and 10 columns +\describe{ +\item{domain}{Data domain} +\item{text_key}{Text key indicating the setting name. \code{'--'} delimiter indicates a field level data mapping} +\item{col_key}{Key for the column mapping} +\item{field_key}{Key for the field mapping (if any)} +\item{type}{type of mapping - "field" or "column"} +\item{label}{Label} +\item{description}{Description} +\item{multiple}{Mapping supports multiple columns/fields } +\item{standard_adam}{Default values for the ADaM data standard} +\item{standard_sdtm}{Default values for the SDTM data standard} +} +} +\source{ +Created for this package +} +\usage{ +meta_ex +} +\description{ +Metadata data frame containing information about the data mapping used to configure safetyGraphics for the Exposure Domain. One record per unique data mapping +} +\keyword{datasets} From 6bd9aff266b58754621cfa6bf9b741e8339ccd03 Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Wed, 19 Apr 2023 11:19:35 -0400 Subject: [PATCH 29/50] tweak domain and chart metadata --- data-raw/meta_vitals.csv | 6 +++--- data/meta_aes.rda | Bin 591 -> 636 bytes data/meta_cm.rda | Bin 527 -> 533 bytes data/meta_dm.rda | Bin 485 -> 487 bytes data/meta_ecg.rda | Bin 1128 -> 1139 bytes data/meta_hepExplorer.rda | Bin 539 -> 537 bytes data/meta_labs.rda | Bin 626 -> 619 bytes data/meta_mh.rda | Bin 530 -> 532 bytes data/meta_vitals.rda | Bin 534 -> 543 bytes inst/config/safetyVitalsOverTime.yaml | 4 ++-- 10 files changed, 5 insertions(+), 5 deletions(-) diff --git a/data-raw/meta_vitals.csv b/data-raw/meta_vitals.csv index f1653d5..a39577e 100644 --- a/data-raw/meta_vitals.csv +++ b/data-raw/meta_vitals.csv @@ -3,6 +3,6 @@ id_col,vitals,id_col,,column,ID column,Unique subject identifier variable name., value_col,vitals,value_col,,column,Value column,Vitals result variable name.,FALSE,AVAL,VSSTRESN measure_col,vitals,measure_col,,column,Measure column,Vitals measure variable name,FALSE,PARAM,VSTEST studyday_col,vitals,studyday_col,,column,Study Day column,Visit day variable name,FALSE,ADY,VSDY -visit_col,vitals,visit_col,,column,Visit column,Visit variable name,FALSE,VISIT,VISIT -visitn_col,vitals,visitn_col,,column,Visit Number column,Visit number variable name,FALSE,VISITNUM,VISITNUM -unit_col,vitals,unit_col,,column,Unit column,Unit of measure variable name,FALSE,,VSSTRESU \ No newline at end of file +visit_col,vitals,visit_col,,column,Visit column,Visit variable name,FALSE,AVISIT,VISIT +visitn_col,vitals,visitn_col,,column,Visit Number column,Visit number variable name,FALSE,AVISITN,VISITNUM +unit_col,vitals,unit_col,,column,Unit column,Unit of measure variable name,FALSE,,VSSTRESU diff --git a/data/meta_aes.rda b/data/meta_aes.rda index 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809393eb05cfb314bf8e45244f564f08fa4c1e28 Mon Sep 17 00:00:00 2001 From: Jeremy Wildfire Date: Fri, 12 May 2023 13:04:29 -0400 Subject: [PATCH 32/50] add param for baseline --- data-raw/meta_hepExplorer.csv | 6 ++++-- data/meta_hepExplorer.rda | Bin 537 -> 644 bytes 2 files changed, 4 insertions(+), 2 deletions(-) diff --git a/data-raw/meta_hepExplorer.csv b/data-raw/meta_hepExplorer.csv index 1632e2d..f3b5bda 100644 --- a/data-raw/meta_hepExplorer.csv +++ b/data-raw/meta_hepExplorer.csv @@ -1,5 +1,7 @@ text_key,domain,col_key,field_key,type,label,description,multiple,standard_adam,standard_sdtm measure_values--ALT,labs,measure_col,ALT,field,Alanine Aminotransferase value,Value used for Alanine Aminotransferase in the specified measure column,FALSE,Alanine Aminotransferase (U/L),Alanine Aminotransferase -measure_values--AST,labs,measure_col,AST,field,Aspartate Aminotransferase value,Value used for Aspartate Aminotransferase in the specified measure column,FALSE,Aspartate 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+baseline--values,labs,baseline_col,,field,Baseline Value,Baseline values for calculating change from baseline,FALSE,, \ No newline at end of file diff --git a/data/meta_hepExplorer.rda b/data/meta_hepExplorer.rda index 7daa0d89f919a4c7d529baa584e5dda66833d5c5..3a1c89741002f814ef3804373d58751aeb5283f0 100644 GIT binary patch literal 644 zcmV-~0(<>JT4*^jL0KkKSz6_5S^xpF|G@wM-qA>7lmR}ZUqHX_-{3$101?0foow#T zfCEUHo}e@U13)wYJxu|SVgNK6fFU$!(?);*00000&;Zo+QJ`c1(?HMwG%zC|00080 zh$fmPJ&K=-JyXp!CzR78)IA6qdV|zIRK|>_j9+1nJenyBu%KIH6oao1i`%m6hy5h? zP4j`=h=hU&Fd|wH$N+gU4$vF|0Hv6K;HoFa^pXf(e7F$l5`!hR21M8R%4~O zZ@9_WVCpb1F^}k>1^P6Qb3_EdCK6K`K@kt?W7i}-GZCs`7{(q&1!+1Jg=Tc|q}147 zwy{a6B?1siBj*EX5kN>d5zp@-EYD0$j7crKD7Ne}Km?NkO5cg3h0U?whz)_n3ZfVq z77w7tW`bLAj`v61Y3vNdbp2KAtt=|6M;@-b9`5tq;7KtVdp`y4{KbOT0@|iiDVKk? zCKq`$5t9QUZLaR`dd+?X>H;h@2Y1LwI3x{i0xSUOip#=xm`yULmgLmFR?tHfq|tQD z%*;k}w#e9AQZ0qCGg&Yr0@LJUD5M!K;xEZF4=pou#c~V{u=VXn#(84i8VpUGPE;*3 zbQ^WXVs_^wiN{cuyABy>az}<7^hRXXb@4}Gqjhh{jdGze8w<-Wv@nR}r4y*$bjRmo zt0=&Hw&%u_l4eoOrv+jOhnj+eR7KMJWS!hD-i_Z$+UOVV-h1R><2GtWJi?ZDYN1DGJN%I9jWT3t&;S7`OiW2hFS2UZ9@DT@=UgH-k*Q0nd6$3X=@^`Lif zMC$w%fPpE&17=C;=NT6LDJZtBji5|`$P*2D+L9iHg%molkIpB@UuNCT1mM)Jah&ne`oJb6K-@V-)4bgMBkP+?twPQXmM6 zSTO2QFNc`J;j}7?hGiUMqFtoB@GTeHXWw6Em!#FvPWn|@MIqhoqiMMP5?j^Oz__5T z&R0arWiqc37Hups?kZGRcH}#>40Zyr7GcjxZ`zMtT5d+eu`vy+R5sgavJzV1VN_6B zMWqh|zF~(3!G&p_tXz>x#m5=d#%;)4aQ;pBJPy-G6kbkqjNurW=r^Nw9$KRG(sOp2 z%$Q-C(>Y;H6_IhjRa3xo8)M^JZQ|&7XUB?aiHOsha28BC>(Y3&9d1#}$*BHF zyZbfp7_^EEt|BbU(OGGN{~c2k4OS6xka8U6@n+ Date: Fri, 26 May 2023 13:26:55 -0400 Subject: [PATCH 33/50] new stack_events function + tests --- NAMESPACE | 2 + R/stack_events.R | 85 ++++++++++++++++++++++++ man/stack_events.Rd | 28 ++++++++ man/standardize_events.Rd | 21 ++++++ tests/testthat/test_stack_events.R | 100 +++++++++++++++++++++++++++++ 5 files changed, 236 insertions(+) create mode 100644 R/stack_events.R create mode 100644 man/stack_events.Rd create mode 100644 man/standardize_events.Rd create mode 100644 tests/testthat/test_stack_events.R diff --git a/NAMESPACE b/NAMESPACE index 9fc2b4f..aac21e3 100644 --- a/NAMESPACE +++ b/NAMESPACE @@ -30,8 +30,10 @@ import(Tplyr) import(dplyr) import(ggplot2) import(htmlwidgets) +import(purrr) import(rlang) import(shiny) +import(tidyr) importFrom(huxtable,as_hux) importFrom(huxtable,set_align) importFrom(huxtable,set_bold) diff --git a/R/stack_events.R b/R/stack_events.R new file mode 100644 index 0000000..11c80aa --- /dev/null +++ b/R/stack_events.R @@ -0,0 +1,85 @@ +#' Combine Event Domains +#' +#' @param data safetyGraphics data object +#' @param settings safetyGraphics settings object +#' @param domains list of safetyGraphics domains. Adverse events ('aes'), concominate medications ('cm') and exposure ('ex') included by default. +#' @return combined dataset with stacked AE and CM data + +#' +#' @examples +#' stack_events( +#' ) + +stack_events <- function(data, settings, domains=c("aes","cm", "ex")){ + + all_events <- domains %>% map(function(domain){ + # check it exists in the data + if(!domain %in% names(data)){ + message(paste0("'",domain, "' data not found in data object and will be skipped in stacked event data.")) + return(NULL) + + }else{ + domain_data <- data[[domain]] + domain_settings<- settings[[domain]] + return(standardize_events(domain_data, domain_settings, domain=domain)) + } + + }) %>% bind_rows + + return(all_events) +} + +#' Create a standardized event data set +#' +#' Create an event data set with a standard set of hard-coded column names using standard safetyGraphics settings and data. The settings for each specified domain should contain valid mappings for ID ("id_col"), event start date ("stdy_col") and event end date ("endy_col"). Missing start day and end day values are extrapolated to NA. All other columns specified in settings are collapsed into a single "details" column. The final standardized data contains the following columns: "id", "domain", "stdy", "endy", "details". +#' +#' @param data safetyGraphics data object +#' @param settings safetyGraphics settings object. +#' @param domains list of safetyGraphics domains. Adverse events ('aes'), concominate medications ('cm') and exposure ('ex') included by default. +#' @return combined dataset with stacked AE and CM data +#' +#' @import purrr +#' @import tidyr + +standardize_events <- function(data, settings, domain=""){ + # stop if id_col doesn't exist + stopifnot("id_col" %in% names(settings)) + stopifnot(settings$id_col %in% names(data)) + + # add stdy_col & endy_col if missing + if(!"stdy_col" %in% names(settings)){ + settings$stdy_col <- 'stdy' + data$stdy<-NA + }else{ + stopifnot(settings$stdy_col %in% names(data)) + } + + if(!"endy_col" %in% names(settings)){ + settings$endy_col <- 'endy' + data$endy<-NA + }else{ + stopifnot(settings$endy_col %in% names(data)) + } + + # make a details object with all other columns in settings + cols<-as.character(settings) + details <- data %>% + select(cols) %>% + select(-settings[["id_col"]]) %>% + select(-settings[["stdy_col"]]) %>% + select(-settings[["endy_col"]]) %>% + imap( ~ paste(.y, .x, sep=": ")) %>% + as_tibble %>% + unite("details", sep="\n") + + # get id, start day and end day + event_data <- data %>% select( + id = settings[["id_col"]], + stdy = settings[["stdy_col"]], + endy = settings[["endy_col"]] + ) %>% + bind_cols(details) %>% + mutate(domain = domain) + + return(event_data) +} \ No newline at end of file diff --git a/man/stack_events.Rd b/man/stack_events.Rd new file mode 100644 index 0000000..76dbe86 --- /dev/null +++ b/man/stack_events.Rd @@ -0,0 +1,28 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/stack_events.R +\name{stack_events} +\alias{stack_events} +\title{Combine Event Domains} +\usage{ +stack_events(data, settings, domains = c("aes", "cm", "ex")) +} +\arguments{ +\item{data}{safetyGraphics data object} + +\item{settings}{safetyGraphics settings object} + +\item{domains}{list of safetyGraphics domains. Adverse events ('aes'), concominate medications ('cm') and exposure ('ex') included by default.} +} +\value{ +combined dataset with stacked AE and CM data +} +\description{ +Combine Event Domains +} +\examples{ +stack_events( + aes_data = params()$data$aes, + cm_data = params()$data$cm, + settings = params()$settings +) +} diff --git a/man/standardize_events.Rd b/man/standardize_events.Rd new file mode 100644 index 0000000..ef8be68 --- /dev/null +++ b/man/standardize_events.Rd @@ -0,0 +1,21 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/stack_events.R +\name{standardize_events} +\alias{standardize_events} +\title{Create a standardized event data set} +\usage{ +standardize_events(data, settings) +} +\arguments{ +\item{data}{safetyGraphics data object} + +\item{settings}{safetyGraphics settings object.} + +\item{domains}{list of safetyGraphics domains. Adverse events ('aes'), concominate medications ('cm') and exposure ('ex') included by default.} +} +\value{ +combined dataset with stacked AE and CM data +} +\description{ +Create an event data set with a standard set of hard-coded column names using standard safetyGraphics settings and data. The settings for each specified domain should contain valid mappings for ID ("id_col"), event start date ("stdy_col") and event end date ("endy_col"). Missing start day and end day values are extrapolated to NA. All other columns specified in settings are collapsed into a single "details" column. The final standardized data contains the following columns: "id", "domain", "stdy", "endy", "details". +} diff --git a/tests/testthat/test_stack_events.R b/tests/testthat/test_stack_events.R new file mode 100644 index 0000000..2117262 --- /dev/null +++ b/tests/testthat/test_stack_events.R @@ -0,0 +1,100 @@ +# Test data + +settings <- list( + aes = list( + id_col = "USUBJID", + bodsys_col = "AEBODSYS", + term_col = "AEDECOD", + term_col = "AETERM", + severity_col = "AESEV", + stdy_col = "AESTDY", + endy_col = "AEENDY" + ), + cm = list( + id_col = "USUBJID", + cmtrt_col = "CMTRT", + stdy_col = "CMSTDY", + endy_col = "CMENDY", + class_col = "CMCLAS", + desc_col = "CMINDC" + ) +) +data <- list(aes=safetyData::sdtm_ae, cm=safetyData::sdtm_cm) + + +# standardize_events tests + +test_that('stops if id_col is missing in settings', { + settings2 <- settings$aes + settings2$id_col <- NULL + expect_error(standardize_events(data$aes, settings2)) +}) + +test_that('stops if id_col in settings is not found in the data', { + settings2$id_col <- "Notanidcol" + expect_error(standardize_events(data$aes, settings2)) +}) + +test_that('stops if stdy_col in settings is not found in the data', { + settings3 <- settings$aes + settings3$stdy_col <- "notacol" + expect_error(standardize_events(data$aes, settings3)) +}) + +test_that('adds col of NA if stdy_col is missing in settings', { + settings3$stdy_col <- NULL + df<-standardize_events(data$aes, settings3) + expect_true(all(is.na(df$stdy))) +}) + +test_that('stops if endy_col in settings is not found in the data', { + settings4 <- settings$aes + settings4$endy_col <- "notacol" + expect_error(standardize_events(data$aes, settings4)) +}) + +test_that('adds col of NA if stdy_col is missing in settings', { + settings4$endy_col <- NULL + df<-standardize_events(data$aes, settings4) + expect_true(all(is.na(df$endy))) +}) + +aedf<-standardize_events(data$aes, settings$aes,domain="aes") +test_that('returns a data.frame with the expected names', { + expect_true(is.data.frame(aedf)) + expect_setequal(names(aedf), c("id","domain","stdy","endy","details")) +}) + +test_that('ae output matches raw data', { + expect_equal(aedf$id, data$aes$USUBJID) + expect_equal(aedf$stdy, data$aes$AESTDY) + expect_equal(aedf$endy, data$aes$AEENDY) +}) + +test_that('ae domain is set correctly',{ + expect_true(all(aedf$domain=="aes")) +}) + + +cmdf<-standardize_events(data$cm, settings$cm, domain="cm") +test_that('cm returns a data.frame with the expected names', { + expect_true(is.data.frame(cmdf)) + expect_setequal(names(cmdf), c("id","domain","stdy","endy","details")) +}) + +#stack events tests + +all<-stack_events(data,settings,domains=c("aes","cm")) +test_that('returns a dataframe with the right rows/cols', { + expect_true(is.data.frame(all)) + expect_setequal(names(all), c("id","domain","stdy","endy","details")) + expect_equal(nrow(all), nrow(data$aes)+nrow(data$cm)) +}) + +all2<-stack_events(data,settings,domains=c("aes","cm","some","other","domains")) +test_that('ignores invalid domains', { + expect_message(stack_events(data,settings,domains=c("aes","cm","some","other","domains"))) + expect_true(is.data.frame(all2)) + expect_setequal(names(all2), c("id","domain","stdy","endy","details")) + expect_equal(nrow(all2), nrow(data$aes)+nrow(data$cm)) +}) \ No newline at end of file From 1997fa6b8720716b326ca6b4fef510f066a6acf9 Mon Sep 17 00:00:00 2001 From: Jeremy Wildfire Date: Fri, 16 Jun 2023 12:42:40 -0400 Subject: [PATCH 34/50] add all_of() --- R/stack_events.R | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/R/stack_events.R b/R/stack_events.R index 11c80aa..568fe73 100644 --- a/R/stack_events.R +++ b/R/stack_events.R @@ -64,7 +64,7 @@ standardize_events <- function(data, settings, domain=""){ # make a details object with all other columns in settings cols<-as.character(settings) details <- data %>% - select(cols) %>% + select(all_of(cols)) %>% select(-settings[["id_col"]]) %>% select(-settings[["stdy_col"]]) %>% select(-settings[["endy_col"]]) %>% From 2edc3ac00d41bbf425c1476188556a4c80384bc4 Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Fri, 23 Jun 2023 11:25:53 -0400 Subject: [PATCH 35/50] remove whitespace --- data-raw/meta_hepExplorer.csv | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/data-raw/meta_hepExplorer.csv b/data-raw/meta_hepExplorer.csv index f3b5bda..5dd46a4 100644 --- a/data-raw/meta_hepExplorer.csv +++ b/data-raw/meta_hepExplorer.csv @@ -1,6 +1,6 @@ text_key,domain,col_key,field_key,type,label,description,multiple,standard_adam,standard_sdtm measure_values--ALT,labs,measure_col,ALT,field,Alanine Aminotransferase value,Value used for Alanine Aminotransferase in the specified measure column,FALSE,Alanine Aminotransferase (U/L),Alanine Aminotransferase -measure_values--AST,labs,measure_col,AST,field,Aspartate Aminotransferase value,Value used for Aspartate Aminotransferase in the specified measure column,FALSE,Aspartate Aminotransferase (U/L),"Aspartate Aminotransferase " +measure_values--AST,labs,measure_col,AST,field,Aspartate Aminotransferase value,Value used for Aspartate Aminotransferase in the specified measure column,FALSE,Aspartate Aminotransferase (U/L),Aspartate Aminotransferase measure_values--TB,labs,measure_col,TB,field,Total Bilirubin value,Value used for Total Bilirubin in the specified measure column,FALSE,Bilirubin (umol/L),Bilirubin measure_values--ALP,labs,measure_col,ALP,field,Alkaline Phosphatase value,Value used for Alkaline Phosphatase in the specified measure column,FALSE,Alkaline Phosphatase (U/L),Alkaline Phosphatase baseline--value_col,labs,baseline_col,,column,Baseline Column,Column for assigning baseline visit,FALSE,ady,lbdy From e7ce61286233d624f77d76728996178edf761d12 Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Fri, 23 Jun 2023 11:27:41 -0400 Subject: [PATCH 36/50] Upper-case column names --- data-raw/meta_hepExplorer.csv | 3 ++- 1 file changed, 2 insertions(+), 1 deletion(-) diff --git a/data-raw/meta_hepExplorer.csv b/data-raw/meta_hepExplorer.csv index 5dd46a4..79d65dc 100644 --- a/data-raw/meta_hepExplorer.csv +++ b/data-raw/meta_hepExplorer.csv @@ -3,5 +3,6 @@ measure_values--ALT,labs,measure_col,ALT,field,Alanine Aminotransferase value,Va measure_values--AST,labs,measure_col,AST,field,Aspartate Aminotransferase value,Value used for Aspartate Aminotransferase in the specified measure column,FALSE,Aspartate Aminotransferase (U/L),Aspartate Aminotransferase measure_values--TB,labs,measure_col,TB,field,Total Bilirubin value,Value used for Total Bilirubin in the specified measure column,FALSE,Bilirubin (umol/L),Bilirubin measure_values--ALP,labs,measure_col,ALP,field,Alkaline Phosphatase value,Value used for Alkaline Phosphatase in the specified measure column,FALSE,Alkaline Phosphatase (U/L),Alkaline Phosphatase -baseline--value_col,labs,baseline_col,,column,Baseline Column,Column for assigning baseline visit,FALSE,ady,lbdy +baseline--value_col,labs,baseline_col,,column,Baseline Column,Column for assigning baseline visit,FALSE,ADY,LBDY + baseline--values,labs,baseline_col,,field,Baseline Value,Baseline values for calculating change from baseline,FALSE,, \ No newline at end of file From 3ed7ef84657a54496f683452e091883f316af0cf Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Fri, 23 Jun 2023 11:28:08 -0400 Subject: [PATCH 37/50] Update data-raw/meta_hepExplorer.csv --- data-raw/meta_hepExplorer.csv | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/data-raw/meta_hepExplorer.csv b/data-raw/meta_hepExplorer.csv index 79d65dc..55f8d51 100644 --- a/data-raw/meta_hepExplorer.csv +++ b/data-raw/meta_hepExplorer.csv @@ -5,4 +5,4 @@ measure_values--TB,labs,measure_col,TB,field,Total Bilirubin value,Value used fo measure_values--ALP,labs,measure_col,ALP,field,Alkaline Phosphatase value,Value used for Alkaline Phosphatase in the specified measure column,FALSE,Alkaline Phosphatase (U/L),Alkaline Phosphatase baseline--value_col,labs,baseline_col,,column,Baseline Column,Column for assigning baseline visit,FALSE,ADY,LBDY -baseline--values,labs,baseline_col,,field,Baseline Value,Baseline values for calculating change from baseline,FALSE,, \ No newline at end of file +baseline--values,labs,baseline_col,,field,Baseline Value,Baseline values for calculating change from baseline,FALSE,1,1 \ No newline at end of file From 38490593fe2d03c030d9de033979a0c72066ede7 Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Fri, 23 Jun 2023 12:35:34 -0400 Subject: [PATCH 38/50] add stack_events to namespace --- NAMESPACE | 7 ++++-- R/stack_events.R | 47 ++++++++++++++++++++++----------------- man/stack_events.Rd | 4 +--- man/standardize_events.Rd | 2 +- 4 files changed, 34 insertions(+), 26 deletions(-) diff --git a/NAMESPACE b/NAMESPACE index aac21e3..989670e 100644 --- a/NAMESPACE +++ b/NAMESPACE @@ -24,16 +24,16 @@ export(safetyOutlierExplorer_server) export(safetyOutlierExplorer_ui) export(safety_outlier_explorer) export(safety_results_over_time) +export(stack_events) +export(standardize_events) export(tendril_chart) import(Tendril) import(Tplyr) import(dplyr) import(ggplot2) import(htmlwidgets) -import(purrr) import(rlang) import(shiny) -import(tidyr) importFrom(huxtable,as_hux) importFrom(huxtable,set_align) importFrom(huxtable,set_bold) @@ -56,7 +56,10 @@ importFrom(plotly,layout) importFrom(plotly,plot_ly) importFrom(plotly,plotlyOutput) importFrom(plotly,renderPlotly) +importFrom(purrr,imap) importFrom(purrr,list_modify) +importFrom(purrr,map) importFrom(rlang,.data) importFrom(stringr,str_detect) +importFrom(tidyr,unite) importFrom(utils,hasName) diff --git a/R/stack_events.R b/R/stack_events.R index 568fe73..1d0d9f7 100644 --- a/R/stack_events.R +++ b/R/stack_events.R @@ -3,27 +3,31 @@ #' @param data safetyGraphics data object #' @param settings safetyGraphics settings object #' @param domains list of safetyGraphics domains. Adverse events ('aes'), concominate medications ('cm') and exposure ('ex') included by default. +#' #' @return combined dataset with stacked AE and CM data - #' #' @examples #' stack_events( #' ) +#' +#' @importFrom purrr map +#' +#' @export -stack_events <- function(data, settings, domains=c("aes","cm", "ex")){ +stack_events <- function(data, settings, domains = c("aes","cm", "ex")) { - all_events <- domains %>% map(function(domain){ + all_events <- domains %>% purrr::map(function(domain) { # check it exists in the data - if(!domain %in% names(data)){ + if (!domain %in% names(data)) { message(paste0("'",domain, "' data not found in data object and will be skipped in stacked event data.")) + return(NULL) - - }else{ + } else { domain_data <- data[[domain]] domain_settings<- settings[[domain]] + return(standardize_events(domain_data, domain_settings, domain=domain)) } - }) %>% bind_rows return(all_events) @@ -38,8 +42,11 @@ stack_events <- function(data, settings, domains=c("aes","cm", "ex")){ #' @param domains list of safetyGraphics domains. Adverse events ('aes'), concominate medications ('cm') and exposure ('ex') included by default. #' @return combined dataset with stacked AE and CM data #' -#' @import purrr -#' @import tidyr +#' @import dplyr +#' @importFrom purrr imap +#' @importFrom tidyr unite +#' +#' @export standardize_events <- function(data, settings, domain=""){ # stop if id_col doesn't exist @@ -64,22 +71,22 @@ standardize_events <- function(data, settings, domain=""){ # make a details object with all other columns in settings cols<-as.character(settings) details <- data %>% - select(all_of(cols)) %>% - select(-settings[["id_col"]]) %>% - select(-settings[["stdy_col"]]) %>% - select(-settings[["endy_col"]]) %>% - imap( ~ paste(.y, .x, sep=": ")) %>% - as_tibble %>% - unite("details", sep="\n") + dplyr::select(dplyr::all_of(cols)) %>% + dplyr::select(-settings[["id_col"]]) %>% + dplyr::select(-settings[["stdy_col"]]) %>% + dplyr::select(-settings[["endy_col"]]) %>% + purrr::imap( ~ paste(.y, .x, sep=": ")) %>% + tibble::as_tibble %>% + tidyr::unite("details", sep="\n") # get id, start day and end day - event_data <- data %>% select( + event_data <- data %>% dplyr::select( id = settings[["id_col"]], stdy = settings[["stdy_col"]], endy = settings[["endy_col"]] ) %>% - bind_cols(details) %>% - mutate(domain = domain) + dplyr::bind_cols(details) %>% + dplyr::mutate(domain = domain) return(event_data) -} \ No newline at end of file +} diff --git a/man/stack_events.Rd b/man/stack_events.Rd index 76dbe86..b3a0ff3 100644 --- a/man/stack_events.Rd +++ b/man/stack_events.Rd @@ -21,8 +21,6 @@ Combine Event Domains } \examples{ stack_events( - aes_data = params()$data$aes, - cm_data = params()$data$cm, - settings = params()$settings ) + } diff --git a/man/standardize_events.Rd b/man/standardize_events.Rd index ef8be68..2554ac0 100644 --- a/man/standardize_events.Rd +++ b/man/standardize_events.Rd @@ -4,7 +4,7 @@ \alias{standardize_events} \title{Create a standardized event data set} \usage{ -standardize_events(data, settings) +standardize_events(data, settings, domain = "") } \arguments{ \item{data}{safetyGraphics data object} From 50c861fec51b76dc5505ac1fd2742fec253f84b4 Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Fri, 23 Jun 2023 15:41:05 -0400 Subject: [PATCH 39/50] fix namespace warnings --- NAMESPACE | 15 ++++++- R/aeExplorer.R | 9 ++-- R/hepExplorer.R | 15 ++++--- R/init_aeExplorer.R | 13 +++--- R/init_cmExplorer.R | 6 ++- R/init_mhExplorer.R | 6 ++- R/init_paneledOutlierExplorer.R | 2 +- R/init_safetyOutlierExplorer.R | 4 +- R/mod_demogRTF.R | 14 ++++-- R/render_widget.R | 2 +- R/safety_outlier_explorer.R | 21 +++++---- R/safety_results_over_time.R | 76 ++++++++++++++++++--------------- R/stack_events.R | 3 +- R/tendril_chart.R | 26 +++++------ R/utils-pipe.R | 14 ++++++ man/aeExplorer.Rd | 7 +-- man/hepExplorer.Rd | 4 +- man/init_aeExplorer.Rd | 5 ++- man/pipe.Rd | 20 +++++++++ man/stack_events.Rd | 3 +- 20 files changed, 165 insertions(+), 100 deletions(-) create mode 100644 R/utils-pipe.R create mode 100644 man/pipe.Rd diff --git a/NAMESPACE b/NAMESPACE index 989670e..00766c2 100644 --- a/NAMESPACE +++ b/NAMESPACE @@ -1,5 +1,6 @@ # Generated by roxygen2: do not edit by hand +export("%>%") export(QT_OutlierExplorer_server) export(QT_OutlierExplorer_ui) export(QT_Outlier_Explorer) @@ -27,13 +28,21 @@ export(safety_results_over_time) export(stack_events) export(standardize_events) export(tendril_chart) -import(Tendril) import(Tplyr) import(dplyr) import(ggplot2) -import(htmlwidgets) import(rlang) import(shiny) +importFrom(DT,DTOutput) +importFrom(DT,renderDT) +importFrom(RColorBrewer,brewer.pal) +importFrom(Tendril,Tendril) +importFrom(forcats,fct_drop) +importFrom(forcats,fct_reorder) +importFrom(htmltools,br) +importFrom(htmltools,div) +importFrom(htmlwidgets,createWidget) +importFrom(htmlwidgets,sizingPolicy) importFrom(huxtable,as_hux) importFrom(huxtable,set_align) importFrom(huxtable,set_bold) @@ -51,6 +60,7 @@ importFrom(pharmaRTF,rtf_doc) importFrom(pharmaRTF,set_column_header_buffer) importFrom(pharmaRTF,set_font_size) importFrom(pharmaRTF,set_ignore_cell_padding) +importFrom(pharmaRTF,write_rtf) importFrom(plotly,animation_slider) importFrom(plotly,layout) importFrom(plotly,plot_ly) @@ -60,6 +70,7 @@ importFrom(purrr,imap) importFrom(purrr,list_modify) importFrom(purrr,map) importFrom(rlang,.data) +importFrom(rlang,sym) importFrom(stringr,str_detect) importFrom(tidyr,unite) importFrom(utils,hasName) diff --git a/R/aeExplorer.R b/R/aeExplorer.R index 47c8722..5f5795d 100644 --- a/R/aeExplorer.R +++ b/R/aeExplorer.R @@ -1,8 +1,8 @@ #' Make standalone aeExplorer html widget #' -#' Convience mapping of render_widget for aeExplorer. +#' Convience mapping of render_widget for aeExplorer. #' -#' @details The [data](https://github.com/RhoInc/aeexplorer/wiki/Data-Guidelines) and +#' The [data](https://github.com/RhoInc/aeexplorer/wiki/Data-Guidelines) and #' [mapping](https://github.com/RhoInc/aeexplorer/wiki/Configuration) should match the specs #' described in the [aeExplorer](https://github.com/RhoInc/aeexplorer/wiki/Configuration) #' JavaScript library. Items passed in ... are added to mapping, and then the list is converted to @@ -50,8 +50,9 @@ #' ) #' } #' -#' @param df data frame containing lab data used to render for aeExplorer. Default is safetyData::adam_adlbc. -#' @param mapping named list with the current data mappings. See details for default mapping. +#' @param data `list` Named list of data frames that includes participant-level subject data (`dm`) +#' and event-level adverse event data (`aes`). +#' @param mapping `list` Named list with current data mappings. See details for default mapping. #' @param ... additional options to be added to mapping. Will overwrite mapping. #' #' @importFrom purrr list_modify diff --git a/R/hepExplorer.R b/R/hepExplorer.R index c6fd682..4c76736 100644 --- a/R/hepExplorer.R +++ b/R/hepExplorer.R @@ -2,7 +2,7 @@ #' #' Convience mapping of render_widget for hepExplorer. #' -#' @details The [data](https://github.com/SafetyGraphics/hep-explorer/wiki/Data-Guidelines) and [mapping](https://github.com/SafetyGraphics/hep-explorer/wiki/Configuration) should match the specs described in the [hepExplorer](https://github.com/SafetyGraphics/hep-explorer/wiki/Configuration) javascript library. Items passed in ... are added to mapping, and then the list is converted to json via `jsonlite::toJSON(mapping, auto_unbox=TRUE, null="null")`. +#' The [data](https://github.com/SafetyGraphics/hep-explorer/wiki/Data-Guidelines) and [mapping](https://github.com/SafetyGraphics/hep-explorer/wiki/Configuration) should match the specs described in the [hepExplorer](https://github.com/SafetyGraphics/hep-explorer/wiki/Configuration) javascript library. Items passed in ... are added to mapping, and then the list is converted to json via `jsonlite::toJSON(mapping, auto_unbox=TRUE, null="null")`. #' #' The default mapping shown below is designed to work with data in the CDISC ADaM format (like `safetydata::adam_adlbc`). #' @@ -66,17 +66,20 @@ #' ) #' } #' -#' @param data data frame containing lab data used to render for hepExplorer. Default is safetyData::adam_adlbc. -#' @param mapping named list with the current data mappings. See details for default mapping. +#' @param data `data.frame` Data frame containing lab data used to render `hepExplorer`. Default: `safetyData::adam_adlbc` +#' @param mapping `list` named list with the current data mappings. See details for default mapping. #' @param ... additional options to be added to mapping. Will overwrite mapping. #' #' @importFrom purrr list_modify #' #' @export -hepExplorer <- function(data=safetyData::adam_adlbc, mapping=NULL, ...){ - - #default mapping +hepExplorer <- function( + data = safetyData::adam_adlbc, + mapping = NULL, + ... +) { + # default mapping if(is.null(mapping)){ mapping <- list( measure_col = "PARAM", diff --git a/R/init_aeExplorer.R b/R/init_aeExplorer.R index 0510876..ec970c5 100644 --- a/R/init_aeExplorer.R +++ b/R/init_aeExplorer.R @@ -1,16 +1,15 @@ #' Initialize Settings for Adverse Event Explorer widget #' -#' @param data adverse events data structured as one record per event. See details for column requirements. -#' @param settings named list of settings +#' @param data `list` Named list of data frames that includes participant-level subject data (`dm`) +#' and event-level adverse event data (`aes`). +#' @param settings `list` Named list of settings. #' #' @return returns list with data and settings #' -#' @importFrom magrittr %>% #' @import dplyr #' #' @export - init_aeExplorer <- function(data, settings) { # creates flag if treatment_col is missing to trigger actions to avoid downstream JS errors and enable visualization of blinded(no treatment_col) data @@ -21,20 +20,20 @@ init_aeExplorer <- function(data, settings) { #if no treatment_col provided, create dummy treatment_col for group setting so that ae explorer JS doesn't bomb if (missing_trt_flag) { - data$dm <- data$dm %>% mutate(group_placeholder="All") + data$dm <- data$dm %>% dplyr::mutate(group_placeholder="All") settings[["dm"]][["treatment_col"]] <- "group_placeholder" } # Merge treatment with adverse events. dm_sub <- data$dm %>% - select( + dplyr::select( settings[["dm"]][["id_col"]], settings[["dm"]][["treatment_col"]] ) # left join to keep all rows in dm (even if there were no AEs) anly <- dm_sub %>% - left_join( + dplyr::left_join( data$aes, settings[['dm']][['id_col']] ) diff --git a/R/init_cmExplorer.R b/R/init_cmExplorer.R index 00a208f..894c076 100644 --- a/R/init_cmExplorer.R +++ b/R/init_cmExplorer.R @@ -5,19 +5,21 @@ #' #' @return returns list with data and settings #' +#' @import dplyr +#' #' @export init_cmExplorer <- function(data, settings) { # Merge treatment with adverse events. dm_sub <- data$dm %>% - select( + dplyr::select( settings[["dm"]][["id_col"]], settings[["dm"]][["treatment_col"]] ) # left join to keep all rows in dm (even if there were no CMs) anly <- dm_sub %>% - left_join( + dplyr::left_join( data$cm, settings[['dm']][['id_col']] ) diff --git a/R/init_mhExplorer.R b/R/init_mhExplorer.R index 17365c0..9c15b58 100644 --- a/R/init_mhExplorer.R +++ b/R/init_mhExplorer.R @@ -5,20 +5,22 @@ #' #' @return returns list with data and settings #' +#' @import dplyr +#' #' @export init_mhExplorer <- function(data, settings) { # Merge treatment with adverse events. dm_sub <- data$dm %>% - select( + dplyr::select( settings[["dm"]][["id_col"]], settings[["dm"]][["treatment_col"]] ) # left join to keep all rows in dm (even if there were no AEs) anly <- dm_sub %>% - left_join( + dplyr::left_join( data$mh, settings[['dm']][['id_col']] ) diff --git a/R/init_paneledOutlierExplorer.R b/R/init_paneledOutlierExplorer.R index b4f6010..b06870e 100644 --- a/R/init_paneledOutlierExplorer.R +++ b/R/init_paneledOutlierExplorer.R @@ -8,7 +8,7 @@ #' @export init_paneledOutlierExplorer <- function(data, settings) { - settings$time_cols <- data_frame( + settings$time_cols <- data.frame( value_col = c(settings[["visit_col"]], settings[["studyday_col"]]), type = c("ordinal", "linear"), order_col = c(settings[["visitn_col"]], "null"), diff --git a/R/init_safetyOutlierExplorer.R b/R/init_safetyOutlierExplorer.R index 2d79694..fbb039d 100644 --- a/R/init_safetyOutlierExplorer.R +++ b/R/init_safetyOutlierExplorer.R @@ -8,7 +8,7 @@ #' @export init_safetyOutlierExplorer <- function(data, settings) { - settings$time_cols <- data_frame( + settings$time_cols <- data.frame( value_col = c(settings[["visit_col"]], settings[["studyday_col"]]), type = c("ordinal", "linear"), order_col = c(settings[["visitn_col"]], "null"), @@ -18,4 +18,4 @@ init_safetyOutlierExplorer <- function(data, settings) { ) return(list(data = data, settings = settings)) -} \ No newline at end of file +} diff --git a/R/mod_demogRTF.R b/R/mod_demogRTF.R index e0a25ca..86e7a11 100644 --- a/R/mod_demogRTF.R +++ b/R/mod_demogRTF.R @@ -4,6 +4,8 @@ #' #' @return returns shiny module UI #' +#' @importFrom DT DTOutput +#' @importFrom htmltools div br #' @import shiny #' #' @export @@ -14,7 +16,7 @@ demogRTF_ui <- function(id) { div( downloadButton(ns("downloadRTF"), "Download RTF", class="btn-primary pull-right"), br(), - DT::dataTableOutput(ns("rtfTable")) + DT::DTOutput(ns("rtfTable")) ) } @@ -29,14 +31,20 @@ demogRTF_ui <- function(id) { #' #' @import ggplot2 #' @import dplyr +#' @importFrom DT renderDT +#' @importFrom pharmaRTF write_rtf +#' @import shiny #' #' @export demogRTF_server <- function(input, output, session, params) { ns <- session$ns - demogTable <- reactive({demogRTF_table(params()$data, params()$settings)}) - output[["rtfTable"]] <- DT::renderDataTable( + demogTable <- reactive({ + demogRTF_table(params()$data, params()$settings) + }) + + output[["rtfTable"]] <- DT::renderDT( demogTable()$table, rownames = FALSE, options = list( diff --git a/R/render_widget.R b/R/render_widget.R index 6658e4d..fc89049 100644 --- a/R/render_widget.R +++ b/R/render_widget.R @@ -4,7 +4,7 @@ #' @param data named list of current data sets #' @param mapping named list with the current data mappings #' -#' @import htmlwidgets +#' @importFrom htmlwidgets createWidget sizingPolicy #' @importFrom jsonlite toJSON #' #' @export diff --git a/R/safety_outlier_explorer.R b/R/safety_outlier_explorer.R index 2989ef2..61b2a41 100644 --- a/R/safety_outlier_explorer.R +++ b/R/safety_outlier_explorer.R @@ -25,35 +25,34 @@ #' safety_outlier_explorer(safetyData::sdtm_lb, settings) #' @return returns a chart object #' -#' @import ggplot2 -#' @import rlang #' @import dplyr +#' @import ggplot2 +#' @importFrom rlang sym #' @importFrom utils hasName #' #' @export safety_outlier_explorer <- function(data, settings) { - params <- aes_( + params <- ggplot2::aes_( x = as.name(settings$studyday_col), y = as.name(settings$value_col), group = as.name(settings$id_col) ) - - if (hasName(settings, "measure_values")) { - sub <- data %>% filter(!!sym(settings$measure_col) %in% settings$measure_values) + if (utils::hasName(settings, "measure_values")) { + sub <- data %>% dplyr::filter(!!rlang::sym(settings$measure_col) %in% settings$measure_values) } else { sub <- data } - p <- ggplot(data = sub, params) + - geom_line(color = "black", alpha = 0.15) + - labs(x = "Study Day", y = "Lab Value", title = "Lab Overview", subtitle = "") + - facet_grid( + p <- ggplot2::ggplot(data = sub, params) + + ggplot2::geom_line(color = "black", alpha = 0.15) + + ggplot2::labs(x = "Study Day", y = "Lab Value", title = "Lab Overview", subtitle = "") + + ggplot2::facet_grid( rows = as.name(settings$measure_col), scales = "free_y" ) + - theme_bw() + ggplot2::theme_bw() return(p) } diff --git a/R/safety_results_over_time.R b/R/safety_results_over_time.R index 44a7afa..b3e6544 100644 --- a/R/safety_results_over_time.R +++ b/R/safety_results_over_time.R @@ -47,10 +47,13 @@ #' #' @return returns a chart object #' -#' @import ggplot2 #' @import dplyr -#' @importFrom utils hasName +#' @importFrom forcats fct_drop fct_reorder +#' @import ggplot2 +#' @importFrom RColorBrewer brewer.pal +#' @importFrom rlang sym #' @importFrom stringr str_detect +#' @importFrom utils hasName #' #' @export @@ -59,11 +62,11 @@ safety_results_over_time <- function(data, settings) { ######################################### # Set default values ######################################### - if (!hasName(settings, "axis")) settings$axis <- "linear" - if (!hasName(settings, "violins")) settings$violins <- FALSE - if (!hasName(settings, "boxplots")) settings$boxplots <- TRUE - if (!hasName(settings, "group_col")) settings$group_col <- "Overall" - if (!hasName(settings, "drop_visit_string")) settings$drop_visit_string <- "" + if (!utils::hasName(settings, "axis")) settings$axis <- "linear" + if (!utils::hasName(settings, "violins")) settings$violins <- FALSE + if (!utils::hasName(settings, "boxplots")) settings$boxplots <- TRUE + if (!utils::hasName(settings, "group_col")) settings$group_col <- "Overall" + if (!utils::hasName(settings, "drop_visit_string")) settings$drop_visit_string <- "" ######################################### # Chart appearance settings @@ -72,34 +75,37 @@ safety_results_over_time <- function(data, settings) { data$Overall <- "Overall" colors <- "gray80" } else { - colors <- c(RColorBrewer::brewer.pal(9, "Set1")[c(2, 3, 1, 4:9)], RColorBrewer::brewer.pal(8, "Set2")) + colors <- c( + RColorBrewer::brewer.pal(9, "Set1")[c(2, 3, 1, 4:9)], + RColorBrewer::brewer.pal(8, "Set2") + ) } alpha <- ifelse(settings[["violins"]] & settings[["boxplots"]], 0.7, 1) - pd <- position_dodge(width = 0.75, preserve = "total") + pd <- ggplot2::position_dodge(width = 0.75, preserve = "total") ######################################### # Prep data ######################################### # Convert settings to symbols ready for standard evaluation - visit_sym <- sym(settings[["visit_col"]]) - visitn_sym <- sym(settings[["visitn_col"]]) - value_sym <- sym(settings[["value_col"]]) - measure_sym <- sym(settings[["measure_col"]]) + visit_sym <- rlang::sym(settings[["visit_col"]]) + visitn_sym <- rlang::sym(settings[["visitn_col"]]) + value_sym <- rlang::sym(settings[["value_col"]]) + measure_sym <- rlang::sym(settings[["measure_col"]]) # Filter to selected measures if specified - if (hasName(settings, "measure_values")) { - dd <- data %>% filter(!!measure_sym %in% settings$measure_values) + if (utils::hasName(settings, "measure_values")) { + dd <- data %>% dplyr::filter(!!measure_sym %in% settings$measure_values) } else { dd <- data } # Drop unscheduled visits if specified if (nchar(settings[["drop_visit_string"]]) > 0) { - dd <- filter( + dd <- dplyr::filter( dd, - !str_detect( + !stringr::str_detect( tolower(!!visit_sym), tolower(settings[["drop_visit_string"]]) ) @@ -107,32 +113,32 @@ safety_results_over_time <- function(data, settings) { } dd <- dd %>% - mutate(!!value_sym := as.numeric(!!value_sym)) %>% # coerce result to numeric - filter(!is.na(!!value_sym)) %>% # drop visits without data - mutate(!!visit_sym := forcats::fct_drop(as.factor(!!visit_sym))) %>% # remove unused factor levels - mutate(!!visit_sym := forcats::fct_reorder(!!visit_sym, !!visitn_sym)) # reorder visits by visit number + dplyr::mutate(!!value_sym := as.numeric(!!value_sym)) %>% # coerce result to numeric + dplyr::filter(!is.na(!!value_sym)) %>% # drop visits without data + dplyr::mutate(!!visit_sym := forcats::fct_drop(as.factor(!!visit_sym))) %>% # remove unused factor levels + dplyr::mutate(!!visit_sym := forcats::fct_reorder(!!visit_sym, !!visitn_sym)) # reorder visits by visit number ######################################### # Create figure ######################################### # initiate plot - overall or by group - params <- aes_( + params <- ggplot2::aes_( x = as.name(settings$visit_col), y = as.name(settings$value_col), color = as.name(settings$group_col) ) - p <- ggplot(data = dd, params) + - scale_color_manual(values = colors) + - facet_grid( + p <- ggplot2::ggplot(data = dd, params) + + ggplot2::scale_color_manual(values = colors) + + ggplot2::facet_grid( rows = as.name(settings$measure_col), scales = "free_y" ) if (settings[["violins"]]) { p <- p + - geom_violin( + ggplot2::geom_violin( alpha = alpha, position = pd ) @@ -140,9 +146,9 @@ safety_results_over_time <- function(data, settings) { if (settings[["boxplots"]]) { p <- p + - geom_boxplot( + ggplot2::geom_boxplot( alpha = alpha, - position = position_dodge2(width = 0.75, preserve = "single"), + position = ggplot2::position_dodge2(width = 0.75, preserve = "single"), fatten = 1, outlier.alpha = 0.8, outlier.shape = 21 @@ -151,8 +157,8 @@ safety_results_over_time <- function(data, settings) { if (settings[["axis"]] == "log") { p <- p + - scale_y_log10() + - annotation_logticks(sides = "l") + ggplot2::scale_y_log10() + + ggplot2::annotation_logticks(sides = "l") summary_fun <- function(x) { log10(mean(10**x)) @@ -162,17 +168,17 @@ safety_results_over_time <- function(data, settings) { } p <- p + - coord_cartesian(clip = "off") + - stat_summary( + ggplot2::coord_cartesian(clip = "off") + + ggplot2::stat_summary( fun.y = summary_fun, geom = "point", position = pd ) p <- p + - theme_bw() + - theme( - axis.text.x = element_text( + ggplot2::theme_bw() + + ggplot2::theme( + axis.text.x = ggplot2::element_text( angle = 45, hjust = 1 ), diff --git a/R/stack_events.R b/R/stack_events.R index 1d0d9f7..aca7ae4 100644 --- a/R/stack_events.R +++ b/R/stack_events.R @@ -7,8 +7,7 @@ #' @return combined dataset with stacked AE and CM data #' #' @examples -#' stack_events( -#' ) +#' stack_events() #' #' @importFrom purrr map #' diff --git a/R/tendril_chart.R b/R/tendril_chart.R index e40c380..1f5356e 100644 --- a/R/tendril_chart.R +++ b/R/tendril_chart.R @@ -19,9 +19,9 @@ #' } #' @return returns a chart object #' -#' @import Tendril -#' @import rlang #' @import dplyr +#' @importFrom Tendril Tendril +#' @importFrom rlang sym #' #' @export #' @@ -31,16 +31,16 @@ tendril_chart <- function(data, settings) { ######################################### # Convert settings to symbols ready for standard evaluation - dm_id_sym <- sym(settings[["dm"]][["id_col"]]) - dm_treatment_sym <- sym(settings[["dm"]][["treatment_col"]]) + dm_id_sym <- rlang::sym(settings[["dm"]][["id_col"]]) + dm_treatment_sym <- rlang::sym(settings[["dm"]][["treatment_col"]]) - ae_id_sym <- sym(settings[["aes"]][["id_col"]]) - ae_bodsys_sym <- sym(settings[["aes"]][["bodsys_col"]]) - ae_stdy_sym <- sym(settings[["aes"]][["stdy_col"]]) + ae_id_sym <- rlang::sym(settings[["aes"]][["id_col"]]) + ae_bodsys_sym <- rlang::sym(settings[["aes"]][["bodsys_col"]]) + ae_stdy_sym <- rlang::sym(settings[["aes"]][["stdy_col"]]) - aes_arm <- left_join( + aes_arm <- dplyr::left_join( data$aes, - data$dm %>% select(!!dm_id_sym, !!dm_treatment_sym), + data$dm %>% dplyr::select(!!dm_id_sym, !!dm_treatment_sym), by = settings[["dm"]][["id_col"]] ) @@ -53,17 +53,17 @@ tendril_chart <- function(data, settings) { # TODO check that the treatments exsits in the data if (length(treatments) < 2) { - all_treatments <- unique(aes_arm %>% pull(!!dm_treatment_sym)) + all_treatments <- unique(aes_arm %>% dplyr::pull(!!dm_treatment_sym)) treatments <- all_treatments[1:2] } # subject data subj <- data$dm %>% - count(!!dm_id_sym, !!dm_treatment_sym) %>% - select(-n) %>% + dplyr::count(!!dm_id_sym, !!dm_treatment_sym) %>% + dplyr::select(-n) %>% as.data.frame() - data.tendril <- Tendril( + data.tendril <- Tendril::Tendril( mydata = aes_arm, rotations = rep(3, dim(aes_arm)[1]), AEfreqThreshold = 5, diff --git a/R/utils-pipe.R b/R/utils-pipe.R new file mode 100644 index 0000000..fd0b1d1 --- /dev/null +++ b/R/utils-pipe.R @@ -0,0 +1,14 @@ +#' Pipe operator +#' +#' See \code{magrittr::\link[magrittr:pipe]{\%>\%}} for details. +#' +#' @name %>% +#' @rdname pipe +#' @keywords internal +#' @export +#' @importFrom magrittr %>% +#' @usage lhs \%>\% rhs +#' @param lhs A value or the magrittr placeholder. +#' @param rhs A function call using the magrittr semantics. +#' @return The result of calling `rhs(lhs)`. +NULL diff --git a/man/aeExplorer.Rd b/man/aeExplorer.Rd index 8aeb594..8af045d 100644 --- a/man/aeExplorer.Rd +++ b/man/aeExplorer.Rd @@ -11,11 +11,12 @@ aeExplorer( ) } \arguments{ -\item{mapping}{named list with the current data mappings. See details for default mapping.} +\item{data}{\code{list} Named list of data frames that includes participant-level subject data (\code{dm}) +and event-level adverse event data (\code{aes}).} -\item{...}{additional options to be added to mapping. Will overwrite mapping.} +\item{mapping}{\code{list} Named list with current data mappings. See details for default mapping.} -\item{df}{data frame containing lab data used to render for aeExplorer. Default is safetyData::adam_adlbc.} +\item{...}{additional options to be added to mapping. Will overwrite mapping.} } \description{ Convience mapping of render_widget for aeExplorer. diff --git a/man/hepExplorer.Rd b/man/hepExplorer.Rd index e1aa6b3..42e24c3 100644 --- a/man/hepExplorer.Rd +++ b/man/hepExplorer.Rd @@ -7,9 +7,9 @@ hepExplorer(data = safetyData::adam_adlbc, mapping = NULL, ...) } \arguments{ -\item{data}{data frame containing lab data used to render for hepExplorer. Default is safetyData::adam_adlbc.} +\item{data}{\code{data.frame} Data frame containing lab data used to render \code{hepExplorer}. Default: \code{safetyData::adam_adlbc}} -\item{mapping}{named list with the current data mappings. See details for default mapping.} +\item{mapping}{\code{list} named list with the current data mappings. See details for default mapping.} \item{...}{additional options to be added to mapping. Will overwrite mapping.} } diff --git a/man/init_aeExplorer.Rd b/man/init_aeExplorer.Rd index 1ca3dab..4adcdba 100644 --- a/man/init_aeExplorer.Rd +++ b/man/init_aeExplorer.Rd @@ -7,9 +7,10 @@ init_aeExplorer(data, settings) } \arguments{ -\item{data}{adverse events data structured as one record per event. See details for column requirements.} +\item{data}{\code{list} Named list of data frames that includes participant-level subject data (\code{dm}) +and event-level adverse event data (\code{aes}).} -\item{settings}{named list of settings} +\item{settings}{\code{list} Named list of settings.} } \value{ returns list with data and settings diff --git a/man/pipe.Rd b/man/pipe.Rd new file mode 100644 index 0000000..a648c29 --- /dev/null +++ b/man/pipe.Rd @@ -0,0 +1,20 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/utils-pipe.R +\name{\%>\%} +\alias{\%>\%} +\title{Pipe operator} +\usage{ +lhs \%>\% rhs +} +\arguments{ +\item{lhs}{A value or the magrittr placeholder.} + +\item{rhs}{A function call using the magrittr semantics.} +} +\value{ +The result of calling \code{rhs(lhs)}. +} +\description{ +See \code{magrittr::\link[magrittr:pipe]{\%>\%}} for details. +} +\keyword{internal} diff --git a/man/stack_events.Rd b/man/stack_events.Rd index b3a0ff3..017f0c0 100644 --- a/man/stack_events.Rd +++ b/man/stack_events.Rd @@ -20,7 +20,6 @@ combined dataset with stacked AE and CM data Combine Event Domains } \examples{ -stack_events( -) +stack_events() } From 51cfeecdeaea6df8c5a55a56296fa739012a0ad3 Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Mon, 26 Jun 2023 10:29:43 -0400 Subject: [PATCH 40/50] fix unit tests --- R/stack_events.R | 5 +- tests/testthat/test_mod_outlierExplorer.R | 5 +- tests/testthat/test_stack_events.R | 57 ++++++++++++++--------- 3 files changed, 41 insertions(+), 26 deletions(-) diff --git a/R/stack_events.R b/R/stack_events.R index aca7ae4..29f2a86 100644 --- a/R/stack_events.R +++ b/R/stack_events.R @@ -74,8 +74,9 @@ standardize_events <- function(data, settings, domain=""){ dplyr::select(-settings[["id_col"]]) %>% dplyr::select(-settings[["stdy_col"]]) %>% dplyr::select(-settings[["endy_col"]]) %>% - purrr::imap( ~ paste(.y, .x, sep=": ")) %>% - tibble::as_tibble %>% + purrr::imap(~ paste(.y, .x, sep=": ")) %>% + dplyr::bind_cols() %>% + tibble::as_tibble() %>% tidyr::unite("details", sep="\n") # get id, start day and end day diff --git a/tests/testthat/test_mod_outlierExplorer.R b/tests/testthat/test_mod_outlierExplorer.R index 424b12d..43ca440 100644 --- a/tests/testthat/test_mod_outlierExplorer.R +++ b/tests/testthat/test_mod_outlierExplorer.R @@ -1,11 +1,12 @@ context("Tests for the outlierExplorer R module") + library(safetyCharts) library(shiny) library(dplyr) library(shinytest) library(testthat) -if(interactive()){ +if (interactive()) { app <- ShinyDriver$new("module_examples/outlierExplorer") initial <- app$getAllValues() } @@ -30,4 +31,4 @@ test_that("Changing the tests updates the chart", { expectUpdate(app, `example1-measures` = c("Albumin"), "example1-outlierExplorer") }) -if(interactive()) app$stop() +if (interactive()) app$stop() diff --git a/tests/testthat/test_stack_events.R b/tests/testthat/test_stack_events.R index 2117262..fccfddb 100644 --- a/tests/testthat/test_stack_events.R +++ b/tests/testthat/test_stack_events.R @@ -1,5 +1,11 @@ +# ---- # Test data +data <- list( + aes = safetyData::sdtm_ae, + cm = safetyData::sdtm_cm +) + settings <- list( aes = list( id_col = "USUBJID", @@ -19,47 +25,54 @@ settings <- list( desc_col = "CMINDC" ) ) -data <- list(aes=safetyData::sdtm_ae, cm=safetyData::sdtm_cm) - +# ---- # standardize_events tests test_that('stops if id_col is missing in settings', { - settings2 <- settings$aes - settings2$id_col <- NULL - expect_error(standardize_events(data$aes, settings2)) + altered_settings <- settings$aes + altered_settings$id_col <- NULL + expect_error(standardize_events(data$aes, altered_settings)) }) test_that('stops if id_col in settings is not found in the data', { - settings2$id_col <- "Notanidcol" - expect_error(standardize_events(data$aes, settings2)) + altered_settings <- settings$aes + altered_settings$id_col <- "Notanidcol" + expect_error(standardize_events(data$aes, altered_settings)) }) test_that('stops if stdy_col in settings is not found in the data', { - settings3 <- settings$aes - settings3$stdy_col <- "notacol" - expect_error(standardize_events(data$aes, settings3)) + altered_settings <- settings$aes + altered_settings$stdy_col <- "notacol" + expect_error(standardize_events(data$aes, altered_settings)) }) test_that('adds col of NA if stdy_col is missing in settings', { - settings3$stdy_col <- NULL - df<-standardize_events(data$aes, settings3) + altered_settings <- settings$aes + altered_settings$stdy_col <- NULL + df<-standardize_events(data$aes, altered_settings) expect_true(all(is.na(df$stdy))) }) test_that('stops if endy_col in settings is not found in the data', { - settings4 <- settings$aes - settings4$endy_col <- "notacol" - expect_error(standardize_events(data$aes, settings4)) + altered_settings <- settings$aes + altered_settings$endy_col <- "notacol" + expect_error(standardize_events(data$aes, altered_settings)) }) test_that('adds col of NA if stdy_col is missing in settings', { - settings4$endy_col <- NULL - df<-standardize_events(data$aes, settings4) + altered_settings <- settings$aes + altered_settings$endy_col <- NULL + df<-standardize_events(data$aes, altered_settings) expect_true(all(is.na(df$endy))) }) -aedf<-standardize_events(data$aes, settings$aes,domain="aes") +aedf <- standardize_events( + data$aes, + settings$aes, + domain="aes" +) + test_that('returns a data.frame with the expected names', { expect_true(is.data.frame(aedf)) expect_setequal(names(aedf), c("id","domain","stdy","endy","details")) @@ -75,16 +88,16 @@ test_that('ae domain is set correctly',{ expect_true(all(aedf$domain=="aes")) }) - cmdf<-standardize_events(data$cm, settings$cm, domain="cm") test_that('cm returns a data.frame with the expected names', { expect_true(is.data.frame(cmdf)) expect_setequal(names(cmdf), c("id","domain","stdy","endy","details")) }) -#stack events tests +# ---- +# stack_events tests -all<-stack_events(data,settings,domains=c("aes","cm")) +all <- stack_events(data,settings,domains=c("aes","cm")) test_that('returns a dataframe with the right rows/cols', { expect_true(is.data.frame(all)) expect_setequal(names(all), c("id","domain","stdy","endy","details")) @@ -97,4 +110,4 @@ test_that('ignores invalid domains', { expect_true(is.data.frame(all2)) expect_setequal(names(all2), c("id","domain","stdy","endy","details")) expect_equal(nrow(all2), nrow(data$aes)+nrow(data$cm)) -}) \ No newline at end of file +}) From 223e8119a3fd1dc30635e602b8eb4d6a5edc1bee Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Tue, 27 Jun 2023 19:23:28 -0400 Subject: [PATCH 41/50] clean up YAMLs and fix outlier explorer --- R/QT_Outlier_Explorer.R | 11 ++++---- R/init_safetyOutlierExplorer.R | 32 ++++++++++++++++++++--- R/mod_demogRTF.R | 2 +- R/paneledOutlierExplorer.R | 6 ++++- R/render_widget.R | 10 ++++--- inst/config/QTpaneledOutlierExplorer.yaml | 6 ++--- inst/config/QTsafetyDeltaDelta.yaml | 2 +- inst/config/QTsafetyHistogram.yaml | 4 +-- inst/config/QTsafetyOutlierExplorer.yaml | 2 +- inst/config/QTsafetyResultsOverTime.yaml | 2 +- inst/config/QTsafetyShiftPlot.yaml | 2 +- inst/config/cmExplorer.yaml | 2 +- inst/config/demogRTF.yaml | 2 +- inst/config/hepExplorer.yaml | 3 ++- inst/config/labdist.yaml | 4 +-- inst/config/mhExplorer.yaml | 2 +- inst/config/paneledOutlierExplorer.yaml | 5 ++-- inst/config/safetyDeltaDelta.yaml | 1 + inst/config/safetyHistogram.yaml | 3 ++- inst/config/safetyOutlierExplorer.yaml | 1 + inst/config/safetyResultsOverTime.yaml | 2 ++ inst/config/safetyShiftPlot.yaml | 2 ++ inst/config/safetyVitalsOverTime.yaml | 4 ++- inst/config/tendril.yaml | 2 +- inst/htmlwidgets/lib/defineWidget.js | 1 + 25 files changed, 78 insertions(+), 35 deletions(-) diff --git a/R/QT_Outlier_Explorer.R b/R/QT_Outlier_Explorer.R index 38ff507..13203e4 100644 --- a/R/QT_Outlier_Explorer.R +++ b/R/QT_Outlier_Explorer.R @@ -19,18 +19,17 @@ #' #' @return returns a chart object #' +#' @import dplyr #' @importFrom plotly plot_ly animation_slider layout #' @import rlang #' @importFrom rlang .data -#' @import dplyr #' #' @export - - - -QT_Outlier_Explorer <- function(data, settings) -{ +QT_Outlier_Explorer <- function( + data, + settings +) { # horizontal reference line hline <- function(y = 0, color = "blue") { diff --git a/R/init_safetyOutlierExplorer.R b/R/init_safetyOutlierExplorer.R index fbb039d..ba3485f 100644 --- a/R/init_safetyOutlierExplorer.R +++ b/R/init_safetyOutlierExplorer.R @@ -5,17 +5,41 @@ #' #' @return returns list with data and settings #' +#' @importFrom dplyr left_join +#' @importFrom stats setNames +#' #' @export init_safetyOutlierExplorer <- function(data, settings) { - settings$time_cols <- data.frame( - value_col = c(settings[["visit_col"]], settings[["studyday_col"]]), + dm <- data$dm %>% + select( + settings$dm$id_col, + setdiff( + names(data$dm), + names(data$labs) + ) + ) + + labs <- data$labs %>% + left_join( + dm, + setNames( + settings$dm$id_col, + settings$labs$id_col + ) + ) + print(names(labs)) + View(labs) + + settings$labs$time_cols <- data.frame( + value_col = c(settings[["labs"]][["visit_col"]], settings[["labs"]][["studyday_col"]]), type = c("ordinal", "linear"), - order_col = c(settings[["visitn_col"]], "null"), + order_col = c(settings[["labs"]][["visitn_col"]], "null"), label = c("Visit", "Study Day"), rotate_tick_labels = c(T, F), vertical_space = c(100, 0) ) + View(settings) - return(list(data = data, settings = settings)) + return(list(data = labs, settings = settings$labs)) } diff --git a/R/mod_demogRTF.R b/R/mod_demogRTF.R index 86e7a11..9b74e2a 100644 --- a/R/mod_demogRTF.R +++ b/R/mod_demogRTF.R @@ -74,8 +74,8 @@ demogRTF_server <- function(input, output, session, params) { #' settings <- list(treatment_col = "ARM", sex_col = "SEX", race_col = "RACE", age_col = "AGE") #' demogRTF_table(safetyData::sdtm_dm, settings) #' -#' @importFrom pharmaRTF rtf_doc add_titles hf_line add_footnotes set_font_size set_ignore_cell_padding set_column_header_buffer #' @importFrom huxtable as_hux set_bold set_align set_valign set_bottom_border set_width set_escape_contents set_col_width +#' @importFrom pharmaRTF rtf_doc add_titles hf_line add_footnotes set_font_size set_ignore_cell_padding set_column_header_buffer #' @import Tplyr #' #' @return rtf doc object diff --git a/R/paneledOutlierExplorer.R b/R/paneledOutlierExplorer.R index 0c96a1c..1f2cfd1 100644 --- a/R/paneledOutlierExplorer.R +++ b/R/paneledOutlierExplorer.R @@ -74,7 +74,11 @@ #' @export #' -paneledOutlierExplorer <- function(df=safetyData::adam_adlbc, mapping=NULL, ...){ +paneledOutlierExplorer <- function( + df=safetyData::adam_adlbc, + mapping=NULL, + ... +) { if(is.null(mapping)){ mapping <- list( measure_col = 'PARAM', diff --git a/R/render_widget.R b/R/render_widget.R index fc89049..dd8edd0 100644 --- a/R/render_widget.R +++ b/R/render_widget.R @@ -8,9 +8,12 @@ #' @importFrom jsonlite toJSON #' #' @export -#' -render_widget <- function(widgetName, data, mapping){ - params<-list(data=data, settings=mapping) + +render_widget <- function(widgetName, data, mapping) { + params <- list( + data=data, + settings=mapping + ) widgetParams <- list( name=widgetName, @@ -18,6 +21,7 @@ render_widget <- function(widgetName, data, mapping){ sizingPolicy = htmlwidgets::sizingPolicy(viewer.suppress=TRUE, browser.external = TRUE), x=list() ) + widgetParams$x$data <- params$data widgetParams$x$rSettings <- params$settings widgetParams$x$settings <- jsonlite::toJSON( diff --git a/inst/config/QTpaneledOutlierExplorer.yaml b/inst/config/QTpaneledOutlierExplorer.yaml index 55dcde5..2ccfc4f 100644 --- a/inst/config/QTpaneledOutlierExplorer.yaml +++ b/inst/config/QTpaneledOutlierExplorer.yaml @@ -1,6 +1,9 @@ env: safetyGraphics label: QT Paneled Outlier Explorer type: htmlwidget +package: safetyCharts +export: true +order: -8.2 domain: - ecg dataSpec: @@ -13,9 +16,6 @@ dataSpec: - value_col - normal_col_low - normal_col_high -package: safetyCharts -export: true -order: -32 workflow: init: init_paneledOutlierExplorer widget: paneledOutlierExplorer diff --git a/inst/config/QTsafetyDeltaDelta.yaml b/inst/config/QTsafetyDeltaDelta.yaml index 99fd78a..d7114c1 100644 --- a/inst/config/QTsafetyDeltaDelta.yaml +++ b/inst/config/QTsafetyDeltaDelta.yaml @@ -3,7 +3,7 @@ label: QT Delta-Delta type: htmlwidget package: safetyCharts export: true -order: -36 +order: -10.2 domain: - ecg dataSpec: diff --git a/inst/config/QTsafetyHistogram.yaml b/inst/config/QTsafetyHistogram.yaml index 1afc550..421c281 100644 --- a/inst/config/QTsafetyHistogram.yaml +++ b/inst/config/QTsafetyHistogram.yaml @@ -2,6 +2,8 @@ env: safetyGraphics label: QT Histogram type: htmlwidget package: safetyCharts +export: true +order: -5.2 domain: - ecg dataSpec: @@ -11,8 +13,6 @@ dataSpec: - value_col - normal_col_low - normal_col_high -export: true -order: -33 workflow: widget: safetyHistogram links: diff --git a/inst/config/QTsafetyOutlierExplorer.yaml b/inst/config/QTsafetyOutlierExplorer.yaml index 46fdf50..217b710 100644 --- a/inst/config/QTsafetyOutlierExplorer.yaml +++ b/inst/config/QTsafetyOutlierExplorer.yaml @@ -3,7 +3,7 @@ label: QT Outlier Explorer type: htmlwidget package: safetyCharts export: true -order: -31 +order: -7.2 domain: - dm - ecg diff --git a/inst/config/QTsafetyResultsOverTime.yaml b/inst/config/QTsafetyResultsOverTime.yaml index 74fc716..c9bf35e 100644 --- a/inst/config/QTsafetyResultsOverTime.yaml +++ b/inst/config/QTsafetyResultsOverTime.yaml @@ -3,7 +3,7 @@ label: QT Results Over Time type: htmlwidget package: safetyCharts export: true -order: -34 +order: -6.2 domain: - ecg dataSpec: diff --git a/inst/config/QTsafetyShiftPlot.yaml b/inst/config/QTsafetyShiftPlot.yaml index 4622604..57e84e8 100644 --- a/inst/config/QTsafetyShiftPlot.yaml +++ b/inst/config/QTsafetyShiftPlot.yaml @@ -3,7 +3,7 @@ label: QT Shift Plot type: htmlwidget package: safetyCharts export: true -order: -35 +order: -9.2 domain: - ecg dataSpec: diff --git a/inst/config/cmExplorer.yaml b/inst/config/cmExplorer.yaml index 23424b1..00ded2b 100644 --- a/inst/config/cmExplorer.yaml +++ b/inst/config/cmExplorer.yaml @@ -3,7 +3,7 @@ label: Conmeds Explorer type: htmlwidget package: safetyCharts export: true -order: 2 +order: 2.1 domain: - dm - cm diff --git a/inst/config/demogRTF.yaml b/inst/config/demogRTF.yaml index 53d1540..645dde8 100644 --- a/inst/config/demogRTF.yaml +++ b/inst/config/demogRTF.yaml @@ -1,6 +1,7 @@ env: safetyGraphics label: Demographics Table type: module +package: safetyCharts export: false order: 1 domain: @@ -12,7 +13,6 @@ dataSpec: - age_col - sex_col - race_col -package: safetyCharts workflow: server: demogRTF_server ui: demogRTF_ui diff --git a/inst/config/hepExplorer.yaml b/inst/config/hepExplorer.yaml index 9c27af4..f5f38ca 100644 --- a/inst/config/hepExplorer.yaml +++ b/inst/config/hepExplorer.yaml @@ -2,6 +2,8 @@ env: safetyGraphics label: Hepatic Safety Explorer type: htmlwidget package: safetyCharts +export: true +order: 9999 domain: - labs dataSpec: @@ -14,7 +16,6 @@ dataSpec: - value_col - normal_col_low - normal_col_high -export: true workflow: widget: hepExplorer links: diff --git a/inst/config/labdist.yaml b/inst/config/labdist.yaml index fcb84d1..9046b41 100644 --- a/inst/config/labdist.yaml +++ b/inst/config/labdist.yaml @@ -2,14 +2,14 @@ env: safetyGraphics label: Labs Distribution type: module package: safetyCharts +export: false +order: -1 domain: - labs dataSpec: labs: - measure_col - value_col -export: false -order: -1 workflow: ui: lab_distribution_ui server: lab_distribution_server diff --git a/inst/config/mhExplorer.yaml b/inst/config/mhExplorer.yaml index 661c943..8bf3c1c 100644 --- a/inst/config/mhExplorer.yaml +++ b/inst/config/mhExplorer.yaml @@ -3,7 +3,7 @@ label: Medical History Explorer type: htmlwidget package: safetyCharts export: true -order: 2 +order: 2.2 domain: - dm - mh diff --git a/inst/config/paneledOutlierExplorer.yaml b/inst/config/paneledOutlierExplorer.yaml index 340d337..6c55498 100644 --- a/inst/config/paneledOutlierExplorer.yaml +++ b/inst/config/paneledOutlierExplorer.yaml @@ -1,6 +1,9 @@ env: safetyGraphics label: Paneled Outlier Explorer type: htmlwidget +package: safetyCharts +export: true +order: 8 domain: - labs dataSpec: @@ -13,8 +16,6 @@ dataSpec: - value_col - normal_col_low - normal_col_high -package: safetyCharts -export: true workflow: init: init_paneledOutlierExplorer widget: paneledOutlierExplorer diff --git a/inst/config/safetyDeltaDelta.yaml b/inst/config/safetyDeltaDelta.yaml index af4b40d..d1d5b24 100644 --- a/inst/config/safetyDeltaDelta.yaml +++ b/inst/config/safetyDeltaDelta.yaml @@ -3,6 +3,7 @@ label: Delta-Delta type: htmlwidget package: safetyCharts export: true +order: 10 domain: - labs dataSpec: diff --git a/inst/config/safetyHistogram.yaml b/inst/config/safetyHistogram.yaml index 9a79cbb..e0b2562 100644 --- a/inst/config/safetyHistogram.yaml +++ b/inst/config/safetyHistogram.yaml @@ -2,6 +2,8 @@ env: safetyGraphics label: Histogram type: htmlwidget package: safetyCharts +export: true +order: 5 domain: - labs dataSpec: @@ -11,7 +13,6 @@ dataSpec: - value_col - normal_col_low - normal_col_high -export: true workflow: widget: safetyHistogram links: diff --git a/inst/config/safetyOutlierExplorer.yaml b/inst/config/safetyOutlierExplorer.yaml index 6e615e4..a4b22ab 100644 --- a/inst/config/safetyOutlierExplorer.yaml +++ b/inst/config/safetyOutlierExplorer.yaml @@ -3,6 +3,7 @@ label: Outlier Explorer type: htmlwidget package: safetyCharts export: true +order: 7 domain: - dm - labs diff --git a/inst/config/safetyResultsOverTime.yaml b/inst/config/safetyResultsOverTime.yaml index 5a07bd1..65967de 100644 --- a/inst/config/safetyResultsOverTime.yaml +++ b/inst/config/safetyResultsOverTime.yaml @@ -3,6 +3,7 @@ label: Results Over Time type: htmlwidget package: safetyCharts export: true +order: 6 domain: - labs dataSpec: @@ -21,3 +22,4 @@ links: Issues: https://github.com/RhoInc/safety-results-over-time/issues Demo: https://rhoinc.github.io/safety-results-over-time/test-page/ safetyCharts: https://github.com/SafetyGraphics/safetycharts + diff --git a/inst/config/safetyShiftPlot.yaml b/inst/config/safetyShiftPlot.yaml index bcd6339..309edfb 100644 --- a/inst/config/safetyShiftPlot.yaml +++ b/inst/config/safetyShiftPlot.yaml @@ -3,6 +3,7 @@ label: Shift Plot type: htmlwidget package: safetyCharts export: true +order: 9 domain: - labs dataSpec: @@ -21,3 +22,4 @@ links: Issues: https://github.com/RhoInc/safety-shift-plot/issues Demo: https://rhoinc.github.io/safety-shift-plot/test-page/ safetyCharts: https://github.com/SafetyGraphics/safetycharts + diff --git a/inst/config/safetyVitalsOverTime.yaml b/inst/config/safetyVitalsOverTime.yaml index c066bfe..610877b 100644 --- a/inst/config/safetyVitalsOverTime.yaml +++ b/inst/config/safetyVitalsOverTime.yaml @@ -3,7 +3,8 @@ label: Vitals Over Time type: htmlwidget package: safetyCharts export: true -domain: +order: -6.1 +domain: - vitals dataSpec: vitals: @@ -21,3 +22,4 @@ links: Issues: https://github.com/RhoInc/safety-results-over-time/issues Demo: https://rhoinc.github.io/safety-results-over-time/test-page/ safetyCharts: https://github.com/SafetyGraphics/safetycharts + diff --git a/inst/config/tendril.yaml b/inst/config/tendril.yaml index 46feb6f..1247e7e 100644 --- a/inst/config/tendril.yaml +++ b/inst/config/tendril.yaml @@ -3,7 +3,7 @@ label: Tendril Plot type: plot package: safetyCharts export: true -order: 4 +order: 9999 domain: - dm - aes diff --git a/inst/htmlwidgets/lib/defineWidget.js b/inst/htmlwidgets/lib/defineWidget.js index 845e97c..01ba31a 100644 --- a/inst/htmlwidgets/lib/defineWidget.js +++ b/inst/htmlwidgets/lib/defineWidget.js @@ -5,6 +5,7 @@ const defineWidget = function(name, fn) { factory: function(el, width, height) { return { renderValue: function(inputs) { + console.log(inputs); // clear element el.innerHTML = ""; From da577da64ce3506085e41cd24932f129f4d088d6 Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Tue, 27 Jun 2023 19:34:45 -0400 Subject: [PATCH 42/50] fix #148 --- R/init_safetyOutlierExplorer.R | 51 +++++++++++++++++------- inst/htmlwidgets/lib/addClickListener.js | 1 - inst/htmlwidgets/lib/defineWidget.js | 1 - 3 files changed, 37 insertions(+), 16 deletions(-) diff --git a/R/init_safetyOutlierExplorer.R b/R/init_safetyOutlierExplorer.R index ba3485f..4f10a9d 100644 --- a/R/init_safetyOutlierExplorer.R +++ b/R/init_safetyOutlierExplorer.R @@ -5,14 +5,15 @@ #' #' @return returns list with data and settings #' -#' @importFrom dplyr left_join +#' @importFrom dplyr left_join select #' @importFrom stats setNames #' #' @export init_safetyOutlierExplorer <- function(data, settings) { + # Keep only those column in DM not present in LB. dm <- data$dm %>% - select( + dplyr::select( settings$dm$id_col, setdiff( names(data$dm), @@ -20,26 +21,48 @@ init_safetyOutlierExplorer <- function(data, settings) { ) ) + # Merge DM onto LB. labs <- data$labs %>% - left_join( + dplyr::left_join( dm, - setNames( + stats::setNames( settings$dm$id_col, settings$labs$id_col ) ) - print(names(labs)) - View(labs) + # Capture both ordinal and discrete longitudinal settings. settings$labs$time_cols <- data.frame( - value_col = c(settings[["labs"]][["visit_col"]], settings[["labs"]][["studyday_col"]]), - type = c("ordinal", "linear"), - order_col = c(settings[["labs"]][["visitn_col"]], "null"), - label = c("Visit", "Study Day"), - rotate_tick_labels = c(T, F), - vertical_space = c(100, 0) + value_col = c( + settings$labs$visit_col, + settings$labs$studyday_col + ), + type = c( + "ordinal", + "linear" + ), + order_col = c( + settings$labs$visitn_col, + "null" + ), + label = c( + "Visit", + "Study Day" + ), + rotate_tick_labels = c( + T, + F + ), + vertical_space = c( + 100, + 0 + ) ) - View(settings) - return(list(data = labs, settings = settings$labs)) + return( + list( + data = labs, + settings = settings$labs + ) + ) } diff --git a/inst/htmlwidgets/lib/addClickListener.js b/inst/htmlwidgets/lib/addClickListener.js index 9491057..c383c4b 100644 --- a/inst/htmlwidgets/lib/addClickListener.js +++ b/inst/htmlwidgets/lib/addClickListener.js @@ -1,6 +1,5 @@ // Communicate participantsSelected event with safetyGraphics when Shiny exists in the environment. const addClickListener = function(instance, el) { - console.log(instance); if (!!Shiny) { const wrap = instance.hasOwnProperty('chart') ? instance.chart.wrap diff --git a/inst/htmlwidgets/lib/defineWidget.js b/inst/htmlwidgets/lib/defineWidget.js index 01ba31a..845e97c 100644 --- a/inst/htmlwidgets/lib/defineWidget.js +++ b/inst/htmlwidgets/lib/defineWidget.js @@ -5,7 +5,6 @@ const defineWidget = function(name, fn) { factory: function(el, width, height) { return { renderValue: function(inputs) { - console.log(inputs); // clear element el.innerHTML = ""; From f7c9edc21fa63bc183689ef29d008fd2d8dc3303 Mon Sep 17 00:00:00 2001 From: nandriychuk Date: Mon, 17 Jul 2023 15:43:57 -0400 Subject: [PATCH 43/50] add fix for tibble --- R/stack_events.R | 3 ++- 1 file changed, 2 insertions(+), 1 deletion(-) diff --git a/R/stack_events.R b/R/stack_events.R index 1d0d9f7..bf50c94 100644 --- a/R/stack_events.R +++ b/R/stack_events.R @@ -76,7 +76,8 @@ standardize_events <- function(data, settings, domain=""){ dplyr::select(-settings[["stdy_col"]]) %>% dplyr::select(-settings[["endy_col"]]) %>% purrr::imap( ~ paste(.y, .x, sep=": ")) %>% - tibble::as_tibble %>% + dplyr::bind_cols() %>% + tibble::as_tibble() %>% tidyr::unite("details", sep="\n") # get id, start day and end day From b7c9404bf93089cf52ee569fceee1a5ebf427439 Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Fri, 28 Jul 2023 13:32:46 -0400 Subject: [PATCH 44/50] fix mod_demogRTF.R --- NAMESPACE | 3 +++ R/mod_demogRTF.R | 7 +++++-- R/stack_events.R | 2 +- 3 files changed, 9 insertions(+), 3 deletions(-) diff --git a/NAMESPACE b/NAMESPACE index 00766c2..acab307 100644 --- a/NAMESPACE +++ b/NAMESPACE @@ -37,6 +37,8 @@ importFrom(DT,DTOutput) importFrom(DT,renderDT) importFrom(RColorBrewer,brewer.pal) importFrom(Tendril,Tendril) +importFrom(dplyr,left_join) +importFrom(dplyr,select) importFrom(forcats,fct_drop) importFrom(forcats,fct_reorder) importFrom(htmltools,br) @@ -71,6 +73,7 @@ importFrom(purrr,list_modify) importFrom(purrr,map) importFrom(rlang,.data) importFrom(rlang,sym) +importFrom(stats,setNames) importFrom(stringr,str_detect) importFrom(tidyr,unite) importFrom(utils,hasName) diff --git a/R/mod_demogRTF.R b/R/mod_demogRTF.R index 9b74e2a..b905811 100644 --- a/R/mod_demogRTF.R +++ b/R/mod_demogRTF.R @@ -82,14 +82,17 @@ demogRTF_server <- function(input, output, session, params) { #' #' @export -demogRTF_table <- function(data, settings) { +demogRTF_table <- function( + data, + settings +) { tplyr_tab <- Tplyr::tplyr_table(data, !!sym(settings$treatment_col)) %>% Tplyr::add_total_group() %>% Tplyr::add_layer( Tplyr::group_desc(!!sym(settings$age_col), by = "Age (Years)") ) %>% Tplyr::add_layer( - Tplyr::group_desc(!!sym(settings$sex_col), by = "Sex") + Tplyr::group_count(!!sym(settings$sex_col), by = "Sex") ) %>% Tplyr::add_layer( Tplyr::group_count(!!sym(settings$race_col), by = "Race") diff --git a/R/stack_events.R b/R/stack_events.R index 29f2a86..7445390 100644 --- a/R/stack_events.R +++ b/R/stack_events.R @@ -23,7 +23,7 @@ stack_events <- function(data, settings, domains = c("aes","cm", "ex")) { return(NULL) } else { domain_data <- data[[domain]] - domain_settings<- settings[[domain]] + domain_settings <- settings[[domain]] return(standardize_events(domain_data, domain_settings, domain=domain)) } From ec560bf71bd94a5f5f8b7203f9fdd616300dfa91 Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Fri, 28 Jul 2023 13:36:12 -0400 Subject: [PATCH 45/50] update r-lib/actions/setup-r to v2 --- .github/workflows/R-CMD-check.yaml | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/.github/workflows/R-CMD-check.yaml b/.github/workflows/R-CMD-check.yaml index a970009..9a13cf8 100644 --- a/.github/workflows/R-CMD-check.yaml +++ b/.github/workflows/R-CMD-check.yaml @@ -15,7 +15,7 @@ jobs: GITHUB_PAT: ${{ secrets.GITHUB_TOKEN }} steps: - uses: actions/checkout@v2 - - uses: r-lib/actions/setup-r@v1 + - uses: r-lib/actions/setup-r@v2 - name: Install dependencies run: | install.packages(c("remotes", "rcmdcheck")) From 876e53e331b6bf0257325d4ec6ec411688c42336 Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Fri, 28 Jul 2023 13:39:13 -0400 Subject: [PATCH 46/50] update imports in description --- DESCRIPTION | 2 ++ 1 file changed, 2 insertions(+) diff --git a/DESCRIPTION b/DESCRIPTION index 30ca381..b178bf7 100644 --- a/DESCRIPTION +++ b/DESCRIPTION @@ -22,6 +22,7 @@ Imports: DT, forcats, ggplot2, + htmltools, htmlwidgets, huxtable, jsonlite, @@ -34,6 +35,7 @@ Imports: shiny, stringr, Tendril, + tidyr, Tplyr Suggests: testthat, From 4fc45c118a2585b621a13b69d90277e7c5b759bf Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Fri, 28 Jul 2023 13:46:21 -0400 Subject: [PATCH 47/50] update namespace and add default arguments to `stack_events` --- NAMESPACE | 2 ++ R/stack_events.R | 29 ++++++++++++++++++++++++++++- man/stack_events.Rd | 12 +++++++++++- 3 files changed, 41 insertions(+), 2 deletions(-) diff --git a/NAMESPACE b/NAMESPACE index acab307..c704517 100644 --- a/NAMESPACE +++ b/NAMESPACE @@ -72,8 +72,10 @@ importFrom(purrr,imap) importFrom(purrr,list_modify) importFrom(purrr,map) importFrom(rlang,.data) +importFrom(rlang,set_names) importFrom(rlang,sym) importFrom(stats,setNames) importFrom(stringr,str_detect) +importFrom(tibble,as_tibble) importFrom(tidyr,unite) importFrom(utils,hasName) diff --git a/R/stack_events.R b/R/stack_events.R index 7445390..18da05f 100644 --- a/R/stack_events.R +++ b/R/stack_events.R @@ -10,10 +10,36 @@ #' stack_events() #' #' @importFrom purrr map +#' @importFrom rlang set_names #' #' @export -stack_events <- function(data, settings, domains = c("aes","cm", "ex")) { +stack_events <- function( + data = list( + aes = safetyData::sdtm_ae, + cm = safetyData::sdtm_cm, + ex = safetyData::sdtm_ex + ), + settings = list( + aes = rlang::set_names( + as.list(safetyCharts::meta_aes$standard_sdtm), + safetyCharts::meta_aes$col_key + ), + cm = rlang::set_names( + as.list(safetyCharts::meta_cm$standard_sdtm), + safetyCharts::meta_cm$col_key + ), + ex = rlang::set_names( + as.list(safetyCharts::meta_ex$standard_sdtm), + safetyCharts::meta_ex$col_key + ) + ), + domains = c( + "aes", + "cm", + "ex" + ) +) { all_events <- domains %>% purrr::map(function(domain) { # check it exists in the data @@ -43,6 +69,7 @@ stack_events <- function(data, settings, domains = c("aes","cm", "ex")) { #' #' @import dplyr #' @importFrom purrr imap +#' @importFrom tibble as_tibble #' @importFrom tidyr unite #' #' @export diff --git a/man/stack_events.Rd b/man/stack_events.Rd index 017f0c0..c595e80 100644 --- a/man/stack_events.Rd +++ b/man/stack_events.Rd @@ -4,7 +4,17 @@ \alias{stack_events} \title{Combine Event Domains} \usage{ -stack_events(data, settings, domains = c("aes", "cm", "ex")) +stack_events( + data = list(aes = safetyData::sdtm_ae, cm = safetyData::sdtm_cm, ex = + safetyData::sdtm_ex), + settings = list(aes = rlang::set_names(as.list(safetyCharts::meta_aes$standard_sdtm), + safetyCharts::meta_aes$col_key), cm = + rlang::set_names(as.list(safetyCharts::meta_cm$standard_sdtm), + safetyCharts::meta_cm$col_key), ex = + rlang::set_names(as.list(safetyCharts::meta_ex$standard_sdtm), + safetyCharts::meta_ex$col_key)), + domains = c("aes", "cm", "ex") +) } \arguments{ \item{data}{safetyGraphics data object} From 11ca0d41c7937c31b47f7515b784d1c7cee1aeab Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Fri, 28 Jul 2023 13:47:20 -0400 Subject: [PATCH 48/50] update description... again --- DESCRIPTION | 1 + 1 file changed, 1 insertion(+) diff --git a/DESCRIPTION b/DESCRIPTION index b178bf7..bf12b3f 100644 --- a/DESCRIPTION +++ b/DESCRIPTION @@ -35,6 +35,7 @@ Imports: shiny, stringr, Tendril, + tibble, tidyr, Tplyr Suggests: From 4340e69cd893cd13829cafda7ef9d6971a63ec48 Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Fri, 28 Jul 2023 13:52:24 -0400 Subject: [PATCH 49/50] fix `check()` warning --- R/stack_events.R | 13 +++++++------ man/stack_events.Rd | 6 +++--- man/standardize_events.Rd | 6 +++--- 3 files changed, 13 insertions(+), 12 deletions(-) diff --git a/R/stack_events.R b/R/stack_events.R index 18da05f..a931370 100644 --- a/R/stack_events.R +++ b/R/stack_events.R @@ -1,8 +1,8 @@ #' Combine Event Domains #' -#' @param data safetyGraphics data object -#' @param settings safetyGraphics settings object -#' @param domains list of safetyGraphics domains. Adverse events ('aes'), concominate medications ('cm') and exposure ('ex') included by default. +#' @param data `list` Named list of data domains. +#' @param settings `list` Named list of settings objects containing column and value mappings. +#' @param domains `character` Vector of data domain names to stack. #' #' @return combined dataset with stacked AE and CM data #' @@ -62,9 +62,10 @@ stack_events <- function( #' #' Create an event data set with a standard set of hard-coded column names using standard safetyGraphics settings and data. The settings for each specified domain should contain valid mappings for ID ("id_col"), event start date ("stdy_col") and event end date ("endy_col"). Missing start day and end day values are extrapolated to NA. All other columns specified in settings are collapsed into a single "details" column. The final standardized data contains the following columns: "id", "domain", "stdy", "endy", "details". #' -#' @param data safetyGraphics data object -#' @param settings safetyGraphics settings object. -#' @param domains list of safetyGraphics domains. Adverse events ('aes'), concominate medications ('cm') and exposure ('ex') included by default. +#' @param data `data.frame` Data domain. +#' @param settings `list` List of column and value mappings. +#' @param domain `character` Name of data domain. +#' #' @return combined dataset with stacked AE and CM data #' #' @import dplyr diff --git a/man/stack_events.Rd b/man/stack_events.Rd index c595e80..eaae58c 100644 --- a/man/stack_events.Rd +++ b/man/stack_events.Rd @@ -17,11 +17,11 @@ stack_events( ) } \arguments{ -\item{data}{safetyGraphics data object} +\item{data}{\code{list} Named list of data domains.} -\item{settings}{safetyGraphics settings object} +\item{settings}{\code{list} Named list of settings objects containing column and value mappings.} -\item{domains}{list of safetyGraphics domains. Adverse events ('aes'), concominate medications ('cm') and exposure ('ex') included by default.} +\item{domains}{\code{character} Vector of data domain names to stack.} } \value{ combined dataset with stacked AE and CM data diff --git a/man/standardize_events.Rd b/man/standardize_events.Rd index 2554ac0..f0ffa22 100644 --- a/man/standardize_events.Rd +++ b/man/standardize_events.Rd @@ -7,11 +7,11 @@ standardize_events(data, settings, domain = "") } \arguments{ -\item{data}{safetyGraphics data object} +\item{data}{\code{data.frame} Data domain.} -\item{settings}{safetyGraphics settings object.} +\item{settings}{\code{list} List of column and value mappings.} -\item{domains}{list of safetyGraphics domains. Adverse events ('aes'), concominate medications ('cm') and exposure ('ex') included by default.} +\item{domain}{\code{character} Name of data domain.} } \value{ combined dataset with stacked AE and CM data From 42c5b01c0aa83c888dd5f79a36ee568f89e0e08f Mon Sep 17 00:00:00 2001 From: Spencer Childress Date: Fri, 20 Sep 2024 14:11:41 -0400 Subject: [PATCH 50/50] Update DESCRIPTION --- DESCRIPTION | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/DESCRIPTION b/DESCRIPTION index bf12b3f..e85c8e3 100644 --- a/DESCRIPTION +++ b/DESCRIPTION @@ -1,6 +1,6 @@ Package: safetyCharts Title: Charts for Monitoring Clinical Trial Safety -Version: 0.3.0 +Version: 0.4.0 Authors@R: person( given = "Jeremy",
    +
    + + + + +
    + +
    +
    +
    +

    Safety Results Over Time plot

    + Source: R/safety_results_over_time.R + +
    + +
    +

    Safety Results Over Time plot

    +
    + + 
    safety_results_over_time(data, settings)
    + +

    Arguments

    + + + + + + + + + + +
    data

    labs data structured as one record per person per visit per measurement. See details for column requirements.

    settings

    named list of settings with the parameters specified below.

    + +

    Value

    + +

    returns a chart object

    +

    Details

    + +

    The settings object provides details the columns in the data set.

    +
      +

    • "value_col"Value column

      • +

    • "measure_col"Measure column

      • +

    • "measure_values"Measure values

      • +

    • "visit_col"Study Visit

      • +

    • "visitn_col"Study Number

      • +

    • "group_col"Grouping column

      • +

    • "violins"Show Violin plots?

      • +

    • "boxplots"Show Box Plots?

      • +

    • "axis"set to "log" to use a log transformed axis, linear otherwise

      • +

    • "drop_visit_string"Drop visits that contain this string. e.g. "unscheduled"

      • +
    + + +

    Examples

    + 
    library(dplyr)
+
    #> 
+#> Attaching package: ‘dplyr’
    #> The following objects are masked from ‘package:stats’:
+#> 
+#>     filter, lag
    #> The following objects are masked from ‘package:base’:
+#> 
+#>     intersect, setdiff, setequal, union
    lb <- safetyData::sdtm_lb
+sub_ids <- unique(lb$USUBJID)[1:100]
+lb<-lb %>% filter(USUBJID %in% sub_ids)
+settings <- list(
+    value_col = "LBORRES",
+    measure_col = "LBTEST",
+    measure_values = c("Chloride"),
+    visit_col = "VISIT",
+    visitn_col = "VISITNUM",
+    axis = "log"
+)
+safety_results_over_time(lb, settings)
+
    #> Warning: `fun.y` is deprecated. Use `fun` instead.
    
+# remove unscheduled visits, add violin plot and 2nd panel
+settings$drop_visit_string <- "unscheduled"
+settings$violins <- TRUE
+settings$measure_values <- c("Albumin")
+safety_results_over_time(lb, settings)
+
    #> Warning: `fun.y` is deprecated. Use `fun` instead.
    #> Warning: Groups with fewer than two data points have been dropped.
    
+# add grouping by treatment
+dm_sub <- safetyData::sdtm_dm %>% select(USUBJID, ARM)
+dm_lb <- dm_sub %>% left_join(lb)
+
    #> Joining, by = "USUBJID"
    settings$group_col <- "ARM"
+safety_results_over_time(dm_lb, settings)
+
    #> Warning: `fun.y` is deprecated. Use `fun` instead.
    #> Warning: Groups with fewer than two data points have been dropped.
    
+
    +
    + +
    + + +
    +
    +

    Developed by Jeremy Wildfire.

    +
    + +
    +

    Site built with pkgdown 1.6.1.

    +
    + +
    +

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