Panache is a web-based interface designed for the visualization of linearized pangenomes. It can be used to show presence/absence information of pangenomic blocks of sequence or genes in a browser-like display.
An instance of Panache is currently running at https://panache.ird.fr/ where anyone can upload its own data.
To see an instance with an existing dataset (Banana Pangenome by Rijzaani H. et al, 2021), you can visit the Banana Genome Hub.
Eloi Durant, François Sabot, Matthieu Conte and Mathieu Rouard. Panache: a Web Viewer for Linearized Pangenomes. BioRxiv. 2021.04.27.441597; doi: https://doi.org/10.1101/2021.04.27.441597
Panache comes with a Docker container. Please make sure your machine already have Docker and Docker-compose (version >=
1.10) installed. If not, you might install it using apt install docker docker-compose
.
After cloning Panache's repository, the container can be built and launched running bash start.sh
(with your sudo
rights enabled; this will both create a build version and serve it with nginx). The web interface will be available
after 1-2 minutes once everything is built. Access the visualization through your localhost (by
default a dev version will be served throught port 8080 and a prod version through port 1337).
The visualization could be served on a custom IP when specified inside the nginx.conf file, instead of (or alongside with) localhost.
If you wish to use another web server directly with the production version of files instead, you will have to
run npm install
, followed with npm install @vue/cli
. Finally make sure to run npm run build
to have
the production version files available, they will be all stored in the directory called 'dist', ready to be served.
Panache offers an interactive view of a presence/absence matrix of genomes and 'pangenome blocks'---such blocks being either sequences or gene. This matrix can be explored similarly to genome browsers, by clicking on the desired location on the miniature.
More descriptive documentation (FAQ, feature description, linearization...) is available at Panache's wiki.
Panache was built to display linear representations of pangenomes instead of graph-like display. With every block ordered on a single string, it becomes easier to parse the representation with human eyes and makes sense of per-node data. It also makes a good baseline for additional information or metadata, that can be layed out on dedicated spaces without overloading the rest of the visualization.
File examples can be find in the public
folder, and detailed information are available in
the Files and Formats section of the wiki
See the Wiki for full documentation, examples and other information.
Panache would not have come to light without the help of Romain Basset (transition to Vue JS framework) and Mel Florance (Docker container and various enhancements). Thank you to Gaetan Droc for setting up Panache on the Banana Genome Hub.
Panache is published under the terms of the MIT LICENSE
panache, noun
an ornamental tuft (as of feathers) especially on a helmet
> The palace guard had a panache on his helmet.dash or flamboyance in style and action
> flashed his … smile and waved with the panache of a big-city mayor. — Joe Morgenstern
Definition from Merriam-Webster