diff --git a/data/testResults/README.md b/data/testResults/README.md
index 1b9e6248..bc5611be 100644
--- a/data/testResults/README.md
+++ b/data/testResults/README.md
@@ -4,7 +4,7 @@ The file here contains results from the [MACAW](https://github.com/Devlin-Moyer/
 
 The test results shown here were obtained by the GitHub Actions run in:
 
-- **PR #959** (MACAW)
+- **PR #960** (MACAW)
 - **PR #962** (gene essentiality)
 
 The results will be updated by any subsequent pull request. Summary results are shown as a comment in the corresponding pull request.
diff --git a/model/Human-GEM.yml b/model/Human-GEM.yml
index 6523031d..671c0456 100644
--- a/model/Human-GEM.yml
+++ b/model/Human-GEM.yml
@@ -161220,7 +161220,7 @@
           - MAM02819e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161235,7 +161235,7 @@
           - MAM01253e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000108932 or ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161250,7 +161250,7 @@
           - MAM01833e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161265,7 +161265,7 @@
           - MAM02772e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161295,7 +161295,7 @@
           - MAM02833e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161310,7 +161310,7 @@
           - MAM01253e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161340,7 +161340,7 @@
           - MAM01252e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161355,7 +161355,7 @@
           - MAM01833e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161370,7 +161370,7 @@
           - MAM02772e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161400,7 +161400,7 @@
           - MAM01410e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161415,7 +161415,7 @@
           - MAM02833e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161430,7 +161430,7 @@
           - MAM02819e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161445,7 +161445,7 @@
           - MAM02819e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161460,7 +161460,7 @@
           - MAM02819e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161475,7 +161475,7 @@
           - MAM02819e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161490,7 +161490,7 @@
           - MAM02819e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161505,7 +161505,7 @@
           - MAM02819e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161535,7 +161535,7 @@
           - MAM02819e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161550,7 +161550,7 @@
           - MAM01306e: 1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161565,7 +161565,7 @@
           - MAM01833e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161580,7 +161580,7 @@
           - MAM02772e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161595,7 +161595,7 @@
           - MAM01306e: 1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161610,7 +161610,7 @@
           - MAM02403e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161625,7 +161625,7 @@
           - MAM01410e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161640,7 +161640,7 @@
           - MAM02833e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161655,7 +161655,7 @@
           - MAM01306e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000108932 or ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161670,7 +161670,7 @@
           - MAM01306e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161685,7 +161685,7 @@
           - MAM01833e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161700,7 +161700,7 @@
           - MAM02772e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161715,7 +161715,7 @@
           - MAM02403e: 1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000100156 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161730,7 +161730,7 @@
           - MAM01410e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161745,7 +161745,7 @@
           - MAM02833e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161760,7 +161760,7 @@
           - MAM01252e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000118596 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem:
@@ -161775,7 +161775,7 @@
           - MAM02772e: -1
       - lower_bound: -1000
       - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000100156 or ENSG00000108932 or ENSG00000118596 or ENSG00000141526 or ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
+      - gene_reaction_rule: "ENSG00000155380 or ENSG00000168679 or ENSG00000170190"
       - rxnFrom: "HMRdatabase"
       - references: "PMID:12739169"
       - subsystem: