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NEWS
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FEATURES IN VERSION 1.03
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o Now the tool also calculates the fold-change and give it in the output.
o Users now have the option to enter background genes for tissue-specific gene enrichment.
FEATURES IN VERSION 1.00
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The TissueEnrich package is used to calculate enrichment of tissue-specific genes in a set of input genes. For example, the user can input the most highly expressed genes from RNA-Seq data, or gene co-expression modules to determine which tissue-specific genes are enriched in those datasets. It has the following three functions.
o "teEnrichment": Given a gene list as input, this function calculates the tissue-specific gene enrichment using tissue-specific genes from either human or mouse RNA-Seq datasets.
o "teGeneRetrieval": Given gene expression data across tissues, this function defines tissue-specific genes by using the algorithm from the HPA.
o "teEnrichmentCustom": Given a gene list and tissue-specific genes from teGeneRetrieval as input, this function calculates the tissue-specific gene enrichment.