diff --git a/pkg/sql/logictest/BUILD.bazel b/pkg/sql/logictest/BUILD.bazel
index a54b6ee2b99b..5d2ed6e64db2 100644
--- a/pkg/sql/logictest/BUILD.bazel
+++ b/pkg/sql/logictest/BUILD.bazel
@@ -58,6 +58,7 @@ go_library(
         "//pkg/kv/kvclient/rangefeed",
         "//pkg/kv/kvserver",
         "//pkg/kv/kvserver/kvserverbase",
+        "//pkg/kv/kvserver/txnwait",
         "//pkg/multitenant/tenantcapabilities",
         "//pkg/security/username",
         "//pkg/server",
diff --git a/pkg/sql/logictest/logic.go b/pkg/sql/logictest/logic.go
index 0f39b9b66c7c..ff73735a9ee7 100644
--- a/pkg/sql/logictest/logic.go
+++ b/pkg/sql/logictest/logic.go
@@ -42,6 +42,7 @@ import (
 	"github.com/cockroachdb/cockroach/pkg/kv/kvclient/rangefeed"
 	"github.com/cockroachdb/cockroach/pkg/kv/kvserver"
 	"github.com/cockroachdb/cockroach/pkg/kv/kvserver/kvserverbase"
+	"github.com/cockroachdb/cockroach/pkg/kv/kvserver/txnwait"
 	"github.com/cockroachdb/cockroach/pkg/multitenant/tenantcapabilities"
 	"github.com/cockroachdb/cockroach/pkg/security/username"
 	"github.com/cockroachdb/cockroach/pkg/server"
@@ -1705,6 +1706,21 @@ func (t *logicTest) newCluster(
 					t.Fatal(err)
 				}
 			}
+			if _, err := conn.Exec(
+				"RESET CLUSTER SETTING kv.closed_timestamp.target_duration",
+			); err != nil {
+				t.Fatal(err)
+			}
+			if _, err := conn.Exec(
+				"RESET CLUSTER SETTING kv.closed_timestamp.side_transport_interval",
+			); err != nil {
+				t.Fatal(err)
+			}
+			if _, err := conn.Exec(
+				"RESET CLUSTER SETTING kv.rangefeed.closed_timestamp_refresh_interval",
+			); err != nil {
+				t.Fatal(err)
+			}
 		}
 
 		capabilities := toa.capabilities
@@ -4323,6 +4339,18 @@ func RunLogicTest(
 	if *printErrorSummary {
 		defer lt.printErrorSummary()
 	}
+	if config.UseSecondaryTenant == logictestbase.Always {
+		// Under multitenant configs running in EngFlow, we have seen that logic
+		// tests can be flaky due to an overload condition where schema change
+		// transactions do not heartbeat quickly enough. This allows background jobs
+		// such as the spanconfig reconciler or the job registry "remove claims from
+		// dead sessions" loop.
+		// See https://github.com/cockroachdb/cockroach/pull/140400#issuecomment-2634346278
+		// and https://github.com/cockroachdb/cockroach/issues/140494#issuecomment-2640208187
+		// for a detailed analysis of this issue.
+		cleanup := txnwait.TestingOverrideTxnLivenessThreshold(30 * time.Second)
+		defer cleanup()
+	}
 	// Each test needs a copy because of Parallel
 	serverArgsCopy := serverArgs
 	serverArgsCopy.ForceProductionValues = serverArgs.ForceProductionValues || nonMetamorphicBatchSizes