diff --git a/packages/profiling-node/src/cpu_profiler.ts b/packages/profiling-node/src/cpu_profiler.ts
index 4897745ededa..ed4ad83e7b31 100644
--- a/packages/profiling-node/src/cpu_profiler.ts
+++ b/packages/profiling-node/src/cpu_profiler.ts
@@ -172,6 +172,12 @@ class Bindings implements V8CpuProfilerBindings {
       return;
     }
 
+    if (typeof PrivateCpuProfilerBindings.startProfiling !== 'function') {
+      DEBUG_BUILD &&
+        logger.log('[Profiling] Native startProfiling function is not available, ignoring call to startProfiling.');
+      return;
+    }
+
     return PrivateCpuProfilerBindings.startProfiling(name);
   }
 
@@ -187,6 +193,12 @@ class Bindings implements V8CpuProfilerBindings {
       return null;
     }
 
+    if (typeof PrivateCpuProfilerBindings.stopProfiling !== 'function') {
+      DEBUG_BUILD &&
+        logger.log('[Profiling] Native stopProfiling function is not available, ignoring call to stopProfiling.');
+      return null;
+    }
+
     return PrivateCpuProfilerBindings.stopProfiling(
       name,
       format as unknown as any,
diff --git a/packages/profiling-node/src/types.ts b/packages/profiling-node/src/types.ts
index 2423ca94651b..9b8f039b3c95 100644
--- a/packages/profiling-node/src/types.ts
+++ b/packages/profiling-node/src/types.ts
@@ -52,15 +52,15 @@ export interface RawChunkCpuProfile extends BaseProfile {
 }
 
 export interface PrivateV8CpuProfilerBindings {
-  startProfiling(name: string): void;
+  startProfiling?: (name: string) => void;
 
-  stopProfiling(
+  stopProfiling?(
     name: string,
     format: ProfileFormat.THREAD,
     threadId: number,
     collectResources: boolean,
   ): RawThreadCpuProfile | null;
-  stopProfiling(
+  stopProfiling?(
     name: string,
     format: ProfileFormat.CHUNK,
     threadId: number,
diff --git a/packages/profiling-node/test/cpu_profiler.test.ts b/packages/profiling-node/test/cpu_profiler.test.ts
index 4db0b98891a3..1719b570e28e 100644
--- a/packages/profiling-node/test/cpu_profiler.test.ts
+++ b/packages/profiling-node/test/cpu_profiler.test.ts
@@ -69,28 +69,28 @@ const assertValidMeasurements = (measurement: RawThreadCpuProfile['measurements'
 
 describe('Private bindings', () => {
   it('does not crash if collect resources is false', async () => {
-    PrivateCpuProfilerBindings.startProfiling('profiled-program');
+    PrivateCpuProfilerBindings.startProfiling!('profiled-program');
     await wait(100);
     expect(() => {
-      const profile = PrivateCpuProfilerBindings.stopProfiling('profiled-program', 0, 0, false);
+      const profile = PrivateCpuProfilerBindings.stopProfiling!('profiled-program', 0, 0, false);
       if (!profile) throw new Error('No profile');
     }).not.toThrow();
   });
 
   it('throws if invalid format is supplied', async () => {
-    PrivateCpuProfilerBindings.startProfiling('profiled-program');
+    PrivateCpuProfilerBindings.startProfiling!('profiled-program');
     await wait(100);
     expect(() => {
-      const profile = PrivateCpuProfilerBindings.stopProfiling('profiled-program', Number.MAX_SAFE_INTEGER, 0, false);
+      const profile = PrivateCpuProfilerBindings.stopProfiling!('profiled-program', Number.MAX_SAFE_INTEGER, 0, false);
       if (!profile) throw new Error('No profile');
     }).toThrow('StopProfiling expects a valid format type as second argument.');
   });
 
   it('collects resources', async () => {
-    PrivateCpuProfilerBindings.startProfiling('profiled-program');
+    PrivateCpuProfilerBindings.startProfiling!('profiled-program');
     await wait(100);
 
-    const profile = PrivateCpuProfilerBindings.stopProfiling('profiled-program', 0, 0, true);
+    const profile = PrivateCpuProfilerBindings.stopProfiling!('profiled-program', 0, 0, true);
     if (!profile) throw new Error('No profile');
 
     expect(profile.resources.length).toBeGreaterThan(0);
@@ -104,10 +104,10 @@ describe('Private bindings', () => {
   });
 
   it('does not collect resources', async () => {
-    PrivateCpuProfilerBindings.startProfiling('profiled-program');
+    PrivateCpuProfilerBindings.startProfiling!('profiled-program');
     await wait(100);
 
-    const profile = PrivateCpuProfilerBindings.stopProfiling('profiled-program', 0, 0, false);
+    const profile = PrivateCpuProfilerBindings.stopProfiling!('profiled-program', 0, 0, false);
     if (!profile) throw new Error('No profile');
 
     expect(profile.resources.length).toBe(0);
@@ -337,4 +337,27 @@ describe('Profiler bindings', () => {
     const hasDeoptimizedFrame = profile.frames.some(f => f.deopt_reasons && f.deopt_reasons.length > 0);
     expect(hasDeoptimizedFrame).toBe(true);
   });
+
+  it('does not crash if the native startProfiling function is not available', async () => {
+    const original = PrivateCpuProfilerBindings.startProfiling;
+    PrivateCpuProfilerBindings.startProfiling = undefined;
+
+    expect(() => {
+      CpuProfilerBindings.startProfiling('profiled-program');
+    }).not.toThrow();
+
+    PrivateCpuProfilerBindings.startProfiling = original;
+  });
+
+  it('does not crash if the native stopProfiling function is not available', async () => {
+    // eslint-disable-next-line @typescript-eslint/unbound-method
+    const original = PrivateCpuProfilerBindings.stopProfiling;
+    PrivateCpuProfilerBindings.stopProfiling = undefined;
+
+    expect(() => {
+      CpuProfilerBindings.stopProfiling('profiled-program', 0);
+    }).not.toThrow();
+
+    PrivateCpuProfilerBindings.stopProfiling = original;
+  });
 });