diff --git a/conda-env.yml b/conda-env.yml
deleted file mode 100644
index 9654478d5..000000000
--- a/conda-env.yml
+++ /dev/null
@@ -1,29 +0,0 @@
-# Conda packages needed by mirgecom.
-# The packages listed here are common to all OS/architectures,
-# Linux systems also need pocl-cuda (which is installed directly by emirge).
-#
-name: ceesd
-channels:
-- conda-forge
-- nodefaults
-dependencies:
-- git
-- gh
-- mypy
-- conda-forge::numpy
-- pocl
-- clinfo
-- pudb
-- islpy
-- oct2py
-- pyopencl
-- pymetis
-- python=3.11
-- pip
-- pytest
-- pylint
-- pydocstyle
-- cantera
-- h5py * nompi_*  # Make sure cantera does not pull in MPI through h5py
-- gmsh
-- vtk
diff --git a/conda-lock.yml b/conda-lock.yml
new file mode 100644
index 000000000..c94fbe907
--- /dev/null
+++ b/conda-lock.yml
@@ -0,0 +1,4309 @@
+# This lock file was generated by conda-lock (https://github.com/conda-incubator/conda-lock). DO NOT EDIT!
+#
+# A "lock file" contains a concrete list of package versions (with checksums) to be installed. Unlike
+# e.g. `conda env create`, the resulting environment will not change as new package versions become
+# available, unless you explicitly update the lock file.
+#
+# Install this environment as "YOURENV" with:
+#     conda-lock install -n YOURENV --file conda-lock.yml
+# To update a single package to the latest version compatible with the version constraints in the source:
+#     conda-lock lock  --lockfile conda-lock.yml --update PACKAGE
+# To re-solve the entire environment, e.g. after changing a version constraint in the source file:
+#     conda-lock -f /home/andreas/src/mirgecom/conda-env.yml -f /home/andreas/src/mirgecom/pyproject.toml --lockfile conda-lock.yml
+metadata:
+  channels:
+  - url: conda-forge
+    used_env_vars: []
+  - url: nodefaults
+    used_env_vars: []
+  content_hash:
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+    linux-ppc64le: ae86bb61008595723036fc55a423e9ff1d6feb46887ce39f086fca8cc7a248d6
+    osx-64: f01c93a44f2e5b329e8e605a02c6237910e29e47b77b991fab60eacd9960087b
+    osx-arm64: 62d7900d7a97aefd89b683ff8642c77b274a25f6c3f8cba1d2361cd7f1c53c3c
+  platforms:
+  - linux-64
+  - linux-ppc64le
+  - osx-64
+  - osx-arm64
+  sources:
+  - /home/andreas/src/mirgecom/conda-env.yml
+  - /home/andreas/src/mirgecom/pyproject.toml
+package:
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+  dependencies: {}
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+    sha256: a5ab4a6a532235cfe4a59a0ffd0dca50a7036e8c9fe83ef4669132c0c0b64fd9
+  manager: conda
+  name: cantera
+  optional: false
+  platform: osx-arm64
+  url: https://conda.anaconda.org/conda-forge/osx-arm64/cantera-2.6.0-py311h8b267df_5.tar.bz2
+  version: 2.6.0
+- category: main
+  dependencies:
+    pytools: '>=2022.1.14'
+  hash:
+    sha256: abc967bae94cb5c11a737a18e76cc8f0408e6f31e979c366c88cb0f305174af9
+  manager: pip
+  name: pymbolic
+  optional: false
+  platform: osx-arm64
+  source:
+    type: url
+    url: https://github.com/inducer/pymbolic/archive/6e9c0a491c9aa7e1bdb9a2f0637db180a408f288.zip#sha256=abc967bae94cb5c11a737a18e76cc8f0408e6f31e979c366c88cb0f305174af9
+  url: https://github.com/inducer/pymbolic/archive/6e9c0a491c9aa7e1bdb9a2f0637db180a408f288.zip
+  version: '2022.2'
+version: 1
diff --git a/pyproject.toml b/pyproject.toml
new file mode 100644
index 000000000..461e45da8
--- /dev/null
+++ b/pyproject.toml
@@ -0,0 +1,56 @@
+# While this is a valid pyproject.toml for use with poetry, we are using
+# conda-lock. To update the lock file (conda-lock.yml), run
+#
+# conda-lock -f pyproject.toml
+#
+# To install the locked versions:
+# conda lock install -n ENVIRONMENT_NAME
+
+# See https://github.com/conda/conda-lock for more.
+
+[build-system]
+requires = [
+    "setuptools!=50",
+    "poetry>=0.12",
+]
+build-backend = "poetry.masonry.api"
+
+[tool.conda-lock]
+platforms = [
+    'osx-64', 'osx-arm64', 'linux-64', 'linux-ppc64le'
+]
+channels = [
+    'conda-forge', 'nodefaults'
+]
+
+[tool.poetry.dependencies]
+python = "3.11"
+pip = "^23.1.2"
+numpy = "^1.15"
+islpy = "^2023.1"
+pyopencl = "^2023.1"
+pymetis = "^2023.1"
+cantera = "^2.6.0"
+
+# FIXME Needs revisions added for other packages
+# NOTE: These will be re-downloaded and re-installed every time
+# 'conda-lock install' is run.
+pymbolic = {url = "https://github.com/inducer/pymbolic/archive/6e9c0a491c9aa7e1bdb9a2f0637db180a408f288.zip#sha256=abc967bae94cb5c11a737a18e76cc8f0408e6f31e979c366c88cb0f305174af9"}
+
+# FIXME: Needs versions added
+# [tool.poetry.dev-dependencies]
+# git
+# gh
+# mypy
+# clinfo
+# pudb
+# oct2py
+# pytest
+# pylint
+# pydocstyle
+# gmsh
+# vtk
+
+[tool.conda-lock.dependencies]
+h5py = "* nompi_*"
+pocl = ">=3.0"