P49711 CTCF (PTHR24404) and Q8NI51 CTCFL (PTHR24406) should probably be in the same tree

[pgaudet]

Similarity is very high

CLUSTAL O(1.2.4) multiple sequence alignment

SP|P49711|CTCF_HUMAN MEGDAVEAIVEESETFIKGKERKTYQRRREGG-QEEDACHL---------PQNQTDGGEV 50
SP|Q8NI51|CTCFL_HUMAN MAATE---ISVLSEQFTKIKELELMPEKGLKEEEKDGVCREKDHRSPSELEAERTSGAFQ 57
* . * ** * * ** : .: :::..: ::.*.

SP|P49711|CTCF_HUMAN VQDVNSSVQMVMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINI 110
SP|Q8NI51|CTCFL_HUMAN DSVLEEEVELV--------------------LAPS---EESEKYILTLQTVHFTSEAVEL 94
. ::..:: :. .:. :.*:: .: :::

SP|P49711|CTCF_HUMAN GELQLVQV------------PVPVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTL 158
SP|Q8NI51|CTCFL_HUMAN QDMSLLSIQQQEGVQVVVQQPGPGLLWLEEGPRQSLQQCVAISI------------QQEL 142
::.*:.: * * : : :.** . .: : *

SP|P49711|CTCF_HUMAN PLPEGFQVVKVGANGEVETLEQGELPPQEDPSWQ----------KDPDYQPPAKKTKKTK 208
SP|Q8NI51|CTCFL_HUMAN YSPQEMEVLQFHA------LEENVMVASEDSKLAVSLAETTGLIKLEEEQEKNQLLAERT 196
: ::::. * :. : . . * : * : : .

SP|P49711|CTCF_HUMAN KSKLRYTE------EGKDVDVSV--YDFEEEQQEGLLSEVNAEKVVGNMKPPKPTKIKKK 260
SP|Q8NI51|CTCFL_HUMAN KEQLFFVETMSGDERSDEIVLTVSNSNVEEQEDQPTAGQADAE-----KAKSTKNQRKTK 251
.: :.* ...:: ::* :.:::: .:.: . .: .

SP|P49711|CTCF_HUMAN GVKKTFQCELCSYTCPRRSNLDRHMKSHTDERPHKCHLCGRAFRTVTLLRNHLNTHTGTR 320
SP|Q8NI51|CTCFL_HUMAN GAKGTFHCDVCMFTSSRMSSFNRHMKTHTSEKPHLCHLCLKTFRTVTLLRNHVNTHTGTR 311
. ::: :. * .::**:.:** **** ::**:

SP|P49711|CTCF_HUMAN PHKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDYASVEVSKLKRHIRSHTGERPFQ 380
SP|Q8NI51|CTCFL_HUMAN PYKCNDCNMAFVTSGELVRHRRYKHTHEKPFKCSMCKYASVEASKLKRHVRSHTGERPFQ 371
:* :****************************..:*******

SP|P49711|CTCF_HUMAN CSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQSGTMKMHILQKHTENVAKFHCP 440
SP|Q8NI51|CTCFL_HUMAN CCQCSYASRDTYKLKRHMRTHSGEKPYECHICHTRFTQSGTMKIHILQKHGENVPKYQCP 431
*. *******::: *** ::

SP|P49711|CTCF_HUMAN HCDTVIARKSDLGVHLRKQHSYIEQGKKCRYCDAVFHERYALIQHQKSHKNEKRFKCDQC 500
SP|Q8NI51|CTCFL_HUMAN HCATIIARKSDLRVHMRNLHAYSAAELKCRYCSAVFHERYALIQHQKTHKNEKRFKCKHC 491
** :****** :*: : .:*.:

SP|P49711|CTCF_HUMAN DYACRQERHMIMHKRTHTGEKPYACSHCDKTFRQKQLLDMHFKRYHDPNFVPAAFVCSKC 560
SP|Q8NI51|CTCFL_HUMAN SYACKQERHMTAHIRTHTGEKPFTCLSCNKCFRQKQLLNAHFRKYHDANFIPTVYKCSKC 551
.:** * *******:: : *****: :: **::.: ****

SP|P49711|CTCF_HUMAN GKTFTRRNTMARHADNCAGPDGVEGENGGETKKSKRGRKRKMRSKKEDSSDSENAEPDLD 620
SP|Q8NI51|CTCFL_HUMAN GKGFSRWINLHRHSEKCGSGEAKSAASGKGR----RTRKRKQTILKEATKGQKEAAKGWK 607
** : .: **:::.. :. .. . * **** ** :...::* . .

SP|P49711|CTCF_HUMAN DNEDEEEPAVE----IEPEPEPQPVTPAPPPAKKRRGRPPGRTNQPKQNQPTAIIQVEDQ 676
SP|Q8NI51|CTCFL_HUMAN EAANGDEAAAEEASTTKGEQFPGEMFPVA--CRET----------------TARV-KEE- 647
: : :* . : * * : *. .:: ** : *:

SP|P49711|CTCF_HUMAN NTGAIENIIVEVKKEPDAEPAEGEEEEAQPAATDAPNGDLTPEMILSMMDR 727
SP|Q8NI51|CTCFL_HUMAN -----------------------------------VDEGVTCEMLLNTMDK 663
: .:* **:*. **:

Thanks, Pascale