diff --git a/doc/conf.py b/doc/conf.py
index 91da1f1b..3e96e59e 100644
--- a/doc/conf.py
+++ b/doc/conf.py
@@ -1,5 +1,3 @@
-# -*- coding: utf-8 -*-
-#
 # Tarantool python client library documentation build configuration file, created by
 # sphinx-quickstart on Tue Nov 29 06:29:57 2011.
 #
diff --git a/setup.py b/setup.py
index 7d84f4fd..3ee55f05 100755
--- a/setup.py
+++ b/setup.py
@@ -1,5 +1,5 @@
 #!/usr/bin/env python
-# -*- coding: utf-8 -*-
+
 import codecs
 import os
 import re
diff --git a/tarantool/__init__.py b/tarantool/__init__.py
index c0b50cfc..9cef1d01 100644
--- a/tarantool/__init__.py
+++ b/tarantool/__init__.py
@@ -1,4 +1,3 @@
-# -*- coding: utf-8 -*-
 # pylint: disable=C0301,W0105,W0401,W0614
 
 import sys
diff --git a/tarantool/connection.py b/tarantool/connection.py
index 702254a1..eb11ab5a 100644
--- a/tarantool/connection.py
+++ b/tarantool/connection.py
@@ -1,4 +1,3 @@
-# -*- coding: utf-8 -*-
 # pylint: disable=C0301,W0105,W0401,W0614
 '''
 This module provides low-level API for Tarantool
@@ -18,10 +17,7 @@
 
 import ctypes
 import ctypes.util
-try:
-    from ctypes import c_ssize_t
-except ImportError:
-    from ctypes import c_longlong as c_ssize_t
+from ctypes import c_ssize_t
 
 import msgpack
 
@@ -85,7 +81,6 @@
     check_key,
     greeting_decode,
     version_id,
-    string_types,
     ENCODING_DEFAULT,
 )
 
@@ -640,7 +635,7 @@ def replace(self, space_name, values):
 
         :rtype: `Response` instance
         '''
-        if isinstance(space_name, string_types):
+        if isinstance(space_name, str):
             space_name = self.schema.get_space(space_name).sid
         request = RequestReplace(self, space_name, values)
         return self._send_request(request)
@@ -697,7 +692,7 @@ class JoinState:
     def _ops_process(self, space, update_ops):
         new_ops = []
         for op in update_ops:
-            if isinstance(op[1], string_types):
+            if isinstance(op[1], str):
                 op = list(op)
                 op[1] = self.schema.get_field(space, op[1])['id']
             new_ops.append(op)
@@ -733,7 +728,7 @@ def insert(self, space_name, values):
 
         :rtype: `Response` instance
         '''
-        if isinstance(space_name, string_types):
+        if isinstance(space_name, str):
             space_name = self.schema.get_space(space_name).sid
         request = RequestInsert(self, space_name, values)
         return self._send_request(request)
@@ -754,9 +749,9 @@ def delete(self, space_name, key, **kwargs):
         index_name = kwargs.get("index", 0)
 
         key = check_key(key)
-        if isinstance(space_name, string_types):
+        if isinstance(space_name, str):
             space_name = self.schema.get_space(space_name).sid
-        if isinstance(index_name, string_types):
+        if isinstance(index_name, str):
             index_name = self.schema.get_index(space_name, index_name).iid
         request = RequestDelete(self, space_name, index_name, key)
         return self._send_request(request)
@@ -826,9 +821,9 @@ def upsert(self, space_name, tuple_value, op_list, **kwargs):
         '''
         index_name = kwargs.get("index", 0)
 
-        if isinstance(space_name, string_types):
+        if isinstance(space_name, str):
             space_name = self.schema.get_space(space_name).sid
-        if isinstance(index_name, string_types):
+        if isinstance(index_name, str):
             index_name = self.schema.get_index(space_name, index_name).iid
         op_list = self._ops_process(space_name, op_list)
         request = RequestUpsert(self, space_name, index_name, tuple_value,
@@ -902,9 +897,9 @@ def update(self, space_name, key, op_list, **kwargs):
         index_name = kwargs.get("index", 0)
 
         key = check_key(key)
-        if isinstance(space_name, string_types):
+        if isinstance(space_name, str):
             space_name = self.schema.get_space(space_name).sid
-        if isinstance(index_name, string_types):
+        if isinstance(index_name, str):
             index_name = self.schema.get_index(space_name, index_name).iid
         op_list = self._ops_process(space_name, op_list)
         request = RequestUpdate(self, space_name, index_name, key, op_list)
@@ -985,9 +980,9 @@ def select(self, space_name, key=None, **kwargs):
         # tuples)
         key = check_key(key, select=True)
 
-        if isinstance(space_name, string_types):
+        if isinstance(space_name, str):
             space_name = self.schema.get_space(space_name).sid
-        if isinstance(index_name, string_types):
+        if isinstance(index_name, str):
             index_name = self.schema.get_index(space_name, index_name).iid
         request = RequestSelect(self, space_name, index_name, key, offset,
                                 limit, iterator_type)
diff --git a/tarantool/connection_pool.py b/tarantool/connection_pool.py
index 6bf78a54..165d655e 100644
--- a/tarantool/connection_pool.py
+++ b/tarantool/connection_pool.py
@@ -1,5 +1,3 @@
-# -*- coding: utf-8 -*-
-
 import abc
 import itertools
 import queue
diff --git a/tarantool/const.py b/tarantool/const.py
index 476af38a..8035f479 100644
--- a/tarantool/const.py
+++ b/tarantool/const.py
@@ -1,4 +1,3 @@
-# -*- coding: utf-8 -*-
 # pylint: disable=C0301,W0105,W0401,W0614
 
 IPROTO_CODE = 0x00
diff --git a/tarantool/dbapi.py b/tarantool/dbapi.py
index cda09948..515e4689 100644
--- a/tarantool/dbapi.py
+++ b/tarantool/dbapi.py
@@ -1,4 +1,3 @@
-# -*- coding: utf-8 -*-
 from tarantool.connection import Connection as BaseConnection
 from tarantool.error import *
 
diff --git a/tarantool/error.py b/tarantool/error.py
index 9ea49d71..6bbe012a 100644
--- a/tarantool/error.py
+++ b/tarantool/error.py
@@ -1,4 +1,3 @@
-# -*- coding: utf-8 -*-
 # pylint: disable=C0301,W0105,W0401,W0614
 '''
 Python DB API compatible exceptions
@@ -6,7 +5,7 @@
 
 The PEP-249 says that database related exceptions must be inherited as follows:
 
-    StandardError
+    Exception
     |__Warning
     |__Error
        |__InterfaceError
@@ -30,21 +29,13 @@
 import warnings
 
 
-try:
-    class Warning(StandardError):
-        '''Exception raised for important warnings
-        like data truncations while inserting, etc. '''
-except NameError:
-    class Warning(Exception):
-        '''Exception raised for important warnings
-        like data truncations while inserting, etc. '''
 
-try:
-    class Error(StandardError):
-        '''Base class for error exceptions'''
-except NameError:
-    class Error(Exception):
-        '''Base class for error exceptions'''
+class Warning(Exception):
+    '''Exception raised for important warnings
+    like data truncations while inserting, etc. '''
+
+class Error(Exception):
+    '''Base class for error exceptions'''
 
 
 class InterfaceError(Error):
diff --git a/tarantool/mesh_connection.py b/tarantool/mesh_connection.py
index 09596d94..33387fd2 100644
--- a/tarantool/mesh_connection.py
+++ b/tarantool/mesh_connection.py
@@ -1,4 +1,3 @@
-# -*- coding: utf-8 -*-
 '''
 This module provides the MeshConnection class with automatic switch
 between Tarantool instances by the basic round-robin strategy.
@@ -33,11 +32,6 @@
     RequestCall
 )
 
-try:
-    string_types = basestring
-except NameError:
-    string_types = str
-
 default_addr_opts = {
     'transport': DEFAULT_TRANSPORT,
     'ssl_key_file': DEFAULT_SSL_KEY_FILE,
@@ -55,7 +49,7 @@ def parse_error(uri, msg):
 
     if not uri:
         return parse_error(uri, 'should not be None or empty string')
-    if not isinstance(uri, string_types):
+    if not isinstance(uri, str):
         return parse_error(uri, 'should be of a string type')
     if uri.count(':') != 1:
         return parse_error(uri, 'does not match host:port scheme')
@@ -117,7 +111,7 @@ def format_error(address, err):
         if 'host' not in result or result['host'] is None:
             return format_error(result,
                                 'host is mandatory for an inet result')
-        if not isinstance(result['host'], string_types):
+        if not isinstance(result['host'], str):
             return format_error(result,
                                 'host must be a string for an inet result')
 
@@ -131,7 +125,7 @@ def format_error(address, err):
 
         # Looks okay.
         return result, None
-    elif isinstance(result['port'], string_types):
+    elif isinstance(result['port'], str):
         # Looks like a unix address.
 
         # Expect no host.
@@ -140,7 +134,7 @@ def format_error(address, err):
                 result, 'host must be unset or None for a unix result')
 
         # Validate port.
-        if not isinstance(result['port'], string_types):
+        if not isinstance(result['port'], str):
             return format_error(result,
                                 'port must be a string for a unix result')
 
diff --git a/tarantool/request.py b/tarantool/request.py
index 44fb5a3c..419f7832 100644
--- a/tarantool/request.py
+++ b/tarantool/request.py
@@ -1,18 +1,13 @@
-# -*- coding: utf-8 -*-
 # pylint: disable=C0301,W0105,W0401,W0614
 '''
 Request types definitions
 '''
 
 import sys
-import collections
 import msgpack
 import hashlib
 
-try:
-    collectionsAbc = collections.abc
-except AttributeError:
-    collectionsAbc = collections
+from collections.abc import Sequence, Mapping
 
 
 from tarantool.error import DatabaseError
@@ -56,7 +51,6 @@
 from tarantool.response import Response, ResponseExecute
 from tarantool.utils import (
     strxor,
-    binary_types
 )
 
 from tarantool.msgpack_ext.packer import default as packer_default
@@ -87,9 +81,6 @@ def __init__(self, conn):
         # The option controls whether to pack binary (non-unicode)
         # string values as mp_bin or as mp_str.
         #
-        # The default behaviour of the Python 2 connector is to pack
-        # both bytes and Unicode strings as mp_str.
-        #
         # The default behaviour of the Python 3 connector (since
         # default encoding is "utf-8") is to pack bytes as mp_bin
         # and Unicode strings as mp_str. encoding=None mode must
@@ -119,7 +110,7 @@ def __init__(self, conn):
         # just always set it for all msgpack versions to get rid
         # of the warning on msgpack-0.5.0 and to keep our
         # behaviour on msgpack-1.0.0.
-        if conn.encoding is None or sys.version_info.major == 2:
+        if conn.encoding is None:
             packer_kwargs['use_bin_type'] = False
         else:
             packer_kwargs['use_bin_type'] = True
@@ -187,7 +178,7 @@ def sha1(values):
             sha = hashlib.sha1()
             for i in values:
                 if i is not None:
-                    if isinstance(i, binary_types):
+                    if isinstance(i, bytes):
                         sha.update(i)
                     else:
                         sha.update(i.encode())
@@ -408,9 +399,9 @@ class RequestExecute(Request):
 
     def __init__(self, conn, sql, args):
         super(RequestExecute, self).__init__(conn)
-        if isinstance(args, collectionsAbc.Mapping):
+        if isinstance(args, Mapping):
             args = [{":%s" % name: value} for name, value in args.items()]
-        elif not isinstance(args, collectionsAbc.Sequence):
+        elif not isinstance(args, Sequence):
             raise TypeError("Parameter type '%s' is not supported. "
                             "Must be a mapping or sequence" % type(args))
 
diff --git a/tarantool/response.py b/tarantool/response.py
index 3e367787..4566acd5 100644
--- a/tarantool/response.py
+++ b/tarantool/response.py
@@ -1,12 +1,6 @@
-# -*- coding: utf-8 -*-
 # pylint: disable=C0301,W0105,W0401,W0614
 
-try:
-    # Python 3.3+
-    from collections.abc import Sequence
-except ImportError:
-    # Python 2
-    from collections import Sequence
+from collections.abc import Sequence
 
 import json
 import msgpack
diff --git a/tarantool/schema.py b/tarantool/schema.py
index ba34885a..3c06963d 100644
--- a/tarantool/schema.py
+++ b/tarantool/schema.py
@@ -1,14 +1,9 @@
-# -*- coding: utf-8 -*-
 # pylint: disable=R0903
 '''
 This module provides the :class:`~tarantool.schema.Schema` class.
 It is a Tarantool schema description.
 '''
 
-from tarantool.utils import (
-    string_types,
-    integer_types,
-)
 from tarantool.error import (
     Error,
     SchemaError,
@@ -151,7 +146,7 @@ def fetch_space(self, space):
             )
         elif len(space_row) == 0 or not len(space_row[0]):
             # We can't find space with this name or id
-            temp_name = 'name' if isinstance(space, string_types) else 'id'
+            temp_name = 'name' if isinstance(space, str) else 'id'
             errmsg = "There's no space with {1} '{0}'".format(space, temp_name)
             raise SchemaError(errmsg)
 
@@ -161,7 +156,7 @@ def fetch_space(self, space):
 
     def fetch_space_from(self, space):
         _index = None
-        if isinstance(space, string_types):
+        if isinstance(space, str):
             _index = const.INDEX_SPACE_NAME
         else:
             _index = const.INDEX_SPACE_PRIMARY
@@ -212,7 +207,7 @@ def fetch_index(self, space_object, index):
             )
         elif len(index_row) == 0 or not len(index_row[0]):
             # We can't find index with this name or id
-            temp_name = 'name' if isinstance(index, string_types) else 'id'
+            temp_name = 'name' if isinstance(index, str) else 'id'
             errmsg = ("There's no index with {2} '{0}'"
                       " in space '{1}'").format(index, space_object.name,
                                                 temp_name)
@@ -229,7 +224,7 @@ def fetch_index_all(self):
 
     def fetch_index_from(self, space, index):
         _index = None
-        if isinstance(index, string_types):
+        if isinstance(index, str):
             _index = const.INDEX_INDEX_NAME
         else:
             _index = const.INDEX_INDEX_PRIMARY
@@ -269,7 +264,7 @@ def get_field(self, space, field):
         try:
             return _space.format[field]
         except:
-            tp = 'name' if isinstance(field, string_types) else 'id'
+            tp = 'name' if isinstance(field, str) else 'id'
             errmsg = "There's no field with {2} '{0}' in space '{1}'".format(
                     field, _space.name, tp
             )
diff --git a/tarantool/space.py b/tarantool/space.py
index 9c3f9fdc..5ebe297c 100644
--- a/tarantool/space.py
+++ b/tarantool/space.py
@@ -1,4 +1,3 @@
-# -*- coding: utf-8 -*-
 # pylint: disable=C0301,W0105,W0401,W0614
 '''
 This module provides the :class:`~tarantool.space.Space` class.
diff --git a/tarantool/utils.py b/tarantool/utils.py
index 7909e12a..1427d9d0 100644
--- a/tarantool/utils.py
+++ b/tarantool/utils.py
@@ -1,39 +1,14 @@
-# -*- coding: utf-8 -*-
 import sys
 import uuid
 
-# Compatibility layer for Python2/Python3
-if sys.version_info.major == 2:
-    string_types     = (basestring, )
-    integer_types    = (int, long)
-    supported_types  = integer_types + string_types + (float,)
+supported_types = (int, str, bytes, float,)
 
-    ENCODING_DEFAULT = None
+ENCODING_DEFAULT = "utf-8"
 
-    if sys.version_info.minor < 6:
-        binary_types = (str, )
-    else:
-        binary_types = (bytes, )
-    from base64 import decodestring as base64_decode
+from base64 import decodebytes as base64_decode
 
-    def strxor(rhs, lhs):
-        return "".join(chr(ord(x) ^ ord(y)) for x, y in zip(rhs, lhs))
-
-elif sys.version_info.major == 3:
-    binary_types    = (bytes, )
-    string_types    = (str, )
-    integer_types   = (int, )
-    supported_types = integer_types + string_types + binary_types + (float,)
-
-    ENCODING_DEFAULT = "utf-8"
-
-    from base64 import decodebytes as base64_decode
-
-    def strxor(rhs, lhs):
-        return bytes([x ^ y for x, y in zip(rhs, lhs)])
-
-else:
-    pass # unreachable
+def strxor(rhs, lhs):
+    return bytes([x ^ y for x, y in zip(rhs, lhs)])
 
 def check_key(*args, **kwargs):
     if 'first' not in kwargs:
diff --git a/test/setup_command.py b/test/setup_command.py
index 1711e2d1..da0cb6c4 100755
--- a/test/setup_command.py
+++ b/test/setup_command.py
@@ -1,5 +1,5 @@
 #!/usr/bin/env python
-# -*- coding: utf-8 -*-
+
 import os
 import sys
 import unittest
diff --git a/test/suites/lib/remote_tarantool_server.py b/test/suites/lib/remote_tarantool_server.py
index fa983f9b..5d6afd77 100644
--- a/test/suites/lib/remote_tarantool_server.py
+++ b/test/suites/lib/remote_tarantool_server.py
@@ -1,5 +1,3 @@
-from __future__ import print_function
-
 import sys
 import os
 import random
diff --git a/test/suites/lib/tarantool_server.py b/test/suites/lib/tarantool_server.py
index 2573a78a..d11ef623 100644
--- a/test/suites/lib/tarantool_server.py
+++ b/test/suites/lib/tarantool_server.py
@@ -1,5 +1,3 @@
-# -*- coding: utf-8 -*-
-
 import os
 import os.path
 import errno
diff --git a/test/suites/test_datetime.py b/test/suites/test_datetime.py
index 17643f6d..a6ce0341 100644
--- a/test/suites/test_datetime.py
+++ b/test/suites/test_datetime.py
@@ -1,7 +1,3 @@
-# -*- coding: utf-8 -*-
-
-from __future__ import print_function
-
 import sys
 import re
 import unittest
diff --git a/test/suites/test_dbapi.py b/test/suites/test_dbapi.py
index 1435bb4f..3873fa84 100644
--- a/test/suites/test_dbapi.py
+++ b/test/suites/test_dbapi.py
@@ -1,7 +1,3 @@
-# -*- coding: utf-8 -*-
-
-from __future__ import print_function
-
 import sys
 import unittest
 
diff --git a/test/suites/test_decimal.py b/test/suites/test_decimal.py
index ad633ddb..4745669f 100644
--- a/test/suites/test_decimal.py
+++ b/test/suites/test_decimal.py
@@ -1,7 +1,3 @@
-# -*- coding: utf-8 -*-
-
-from __future__ import print_function
-
 import sys
 import unittest
 import decimal
diff --git a/test/suites/test_dml.py b/test/suites/test_dml.py
index 6463778f..6c7808f6 100644
--- a/test/suites/test_dml.py
+++ b/test/suites/test_dml.py
@@ -1,7 +1,3 @@
-# -*- coding: utf-8 -*-
-
-from __future__ import print_function
-
 import sys
 import unittest
 import tarantool
@@ -183,7 +179,7 @@ def test_07_call_16(self):
         ans = con.call('fiber.time64')
         self.assertEqual(len(ans), 1)
         self.assertEqual(len(ans[0]), 1)
-        self.assertIsInstance(ans[0][0], tarantool.utils.integer_types)
+        self.assertIsInstance(ans[0][0], int)
         ans = con.call('uuid.str')
         self.assertEqual(len(ans), 1)
         self.assertEqual(len(ans[0]), 1)
@@ -207,7 +203,7 @@ def test_07_call_17(self):
         self.assertIsInstance(ans[0], float)
         ans = con.call('fiber.time64')
         self.assertEqual(len(ans), 1)
-        self.assertIsInstance(ans[0], tarantool.utils.integer_types)
+        self.assertIsInstance(ans[0], int)
         ans = con.call('uuid.str')
         self.assertEqual(len(ans), 1)
         self.assertIsInstance(ans[0], str)
diff --git a/test/suites/test_encoding.py b/test/suites/test_encoding.py
index f5f5f8c0..e434b2d5 100644
--- a/test/suites/test_encoding.py
+++ b/test/suites/test_encoding.py
@@ -1,7 +1,3 @@
-# -*- coding: utf-8 -*-
-
-from __future__ import print_function
-
 import sys
 import unittest
 import tarantool
diff --git a/test/suites/test_execute.py b/test/suites/test_execute.py
index 53fd9f2e..f90b2fc3 100644
--- a/test/suites/test_execute.py
+++ b/test/suites/test_execute.py
@@ -1,7 +1,3 @@
-# -*- coding: utf-8 -*-
-
-from __future__ import print_function
-
 import sys
 import unittest
 
diff --git a/test/suites/test_interval.py b/test/suites/test_interval.py
index 0913dacb..63a3c0ca 100644
--- a/test/suites/test_interval.py
+++ b/test/suites/test_interval.py
@@ -1,7 +1,3 @@
-# -*- coding: utf-8 -*-
-
-from __future__ import print_function
-
 import re
 import sys
 import unittest
diff --git a/test/suites/test_mesh.py b/test/suites/test_mesh.py
index df0b059a..cb0bce7c 100644
--- a/test/suites/test_mesh.py
+++ b/test/suites/test_mesh.py
@@ -1,7 +1,3 @@
-# -*- coding: utf-8 -*-
-
-from __future__ import print_function
-
 import sys
 import unittest
 import warnings
diff --git a/test/suites/test_pool.py b/test/suites/test_pool.py
index 12263d79..f10b6287 100644
--- a/test/suites/test_pool.py
+++ b/test/suites/test_pool.py
@@ -1,7 +1,3 @@
-# -*- coding: utf-8 -*-
-
-from __future__ import print_function
-
 import sys
 import time
 import unittest
diff --git a/test/suites/test_protocol.py b/test/suites/test_protocol.py
index 2e31f185..9442b0b0 100644
--- a/test/suites/test_protocol.py
+++ b/test/suites/test_protocol.py
@@ -1,7 +1,3 @@
-# -*- coding: utf-8 -*-
-
-from __future__ import print_function
-
 import sys
 import unittest
 from tarantool.utils import greeting_decode, version_id
diff --git a/test/suites/test_reconnect.py b/test/suites/test_reconnect.py
index 403fd351..fc41cb57 100644
--- a/test/suites/test_reconnect.py
+++ b/test/suites/test_reconnect.py
@@ -1,7 +1,3 @@
-# -*- coding: utf-8 -*-
-
-from __future__ import print_function
-
 import sys
 import unittest
 import warnings
diff --git a/test/suites/test_schema.py b/test/suites/test_schema.py
index c5f12282..f289fe74 100644
--- a/test/suites/test_schema.py
+++ b/test/suites/test_schema.py
@@ -1,7 +1,3 @@
-# -*- coding: utf-8 -*-
-
-from __future__ import print_function
-
 import sys
 import unittest
 import tarantool
diff --git a/test/suites/test_ssl.py b/test/suites/test_ssl.py
index c2d4ba2b..977474f3 100644
--- a/test/suites/test_ssl.py
+++ b/test/suites/test_ssl.py
@@ -1,5 +1,3 @@
-# -*- coding: utf-8 -*-
-
 import os
 import sys
 import unittest
diff --git a/test/suites/test_uuid.py b/test/suites/test_uuid.py
index c51c8c82..a0203538 100644
--- a/test/suites/test_uuid.py
+++ b/test/suites/test_uuid.py
@@ -1,7 +1,3 @@
-# -*- coding: utf-8 -*-
-
-from __future__ import print_function
-
 import sys
 import unittest
 import uuid