diff --git a/src/addr_validate.rs b/src/addr_validate.rs
index cd39bcac..6a136e76 100644
--- a/src/addr_validate.rs
+++ b/src/addr_validate.rs
@@ -28,7 +28,7 @@ fn create_pipe() -> nix::Result<(i32, i32)> {
 }
 
 #[inline]
-#[cfg(any(target_os = "macos", target_os = "freebsd"))]
+#[cfg(any(target_os = "macos", target_os = "freebsd", target_os = "openbsd"))]
 fn create_pipe() -> nix::Result<(i32, i32)> {
     use nix::fcntl::{fcntl, FcntlArg, FdFlag, OFlag};
     use nix::unistd::pipe;
diff --git a/src/profiler.rs b/src/profiler.rs
index 69aeadbd..05ece635 100644
--- a/src/profiler.rs
+++ b/src/profiler.rs
@@ -248,6 +248,11 @@ impl ErrnoProtector {
                 let errno = *libc::__error();
                 Self(errno)
             }
+            #[cfg(target_os = "openbsd")]
+            {
+                let errno = *libc::__errno();
+                Self(errno)
+            }
         }
     }
 }
@@ -267,6 +272,10 @@ impl Drop for ErrnoProtector {
             {
                 *libc::__error() = self.0;
             }
+            #[cfg(target_os = "openbsd")]
+            {
+                *libc::__errno() = self.0;
+            }
         }
     }
 }
@@ -306,6 +315,8 @@ extern "C" fn perf_signal_handler(
 
                 #[cfg(all(target_arch = "x86_64", target_os = "freebsd"))]
                 let addr = unsafe { (*ucontext).uc_mcontext.mc_rip as usize };
+                #[cfg(all(target_arch = "x86_64", target_os = "openbsd"))]
+                let addr = unsafe { (*ucontext).sc_rip as usize };
 
                 #[cfg(all(target_arch = "x86_64", target_os = "macos"))]
                 let addr = unsafe {