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.Rhistory

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library("devtools")
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install_github("AlexandrovLab/SigProfilerMatrixGeneratorR")
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install_github("AlexandrovLab/SigProfilerMatrixGeneratorR")
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library("reticulate")
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README.md

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# SigProfilerMatrixGeneratorR
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An R wrapper for running the SigProfilerMatrixGenerator (https://osf.io/s93d5/wiki/home/) framework.
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**INTRODUCTION**
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The purpose of this document is to provide a guide for using the SigProfilerMatrixGenerator framework to generate mutational matrices for a set of samples with associated mutational catalogues. An extensive Wiki page detailing the usage of this tool can be found at https://osf.io/s93d5/wiki/home/. For users that prefer working in a Python environment, the tool is written in Python and can be found and installed from: https://github.com/AlexandrovLab/SigProfilerMatrixGenerator
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**CITATION**
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E.N. Bergstrom, M.N. Huang, U. Mahto, M. Barnes, M.R. Stratton, S.G. Rozen, and L.B. Alexandrov (2019) SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events. https://www.biorxiv.org/content/10.1101/653097v1
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Bergstrom EN, Huang MN, Mahto U, Barnes M, Stratton MR, Rozen SG, Alexandrov LB: SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events. BMC Genomics 2019, 20:685
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https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-019-6041-2
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**COPYRIGHT**
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Copyright (c) 2019, Erik Bergstrom [Alexandrov Lab] All rights reserved.
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Copyright (c) 2020, Erik Bergstrom [Alexandrov Lab] All rights reserved.
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Redistribution and use in source and binary forms, with or without modification, are permitted provided that the following conditions are met:
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