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Copy pathLIF1CH0PD1_sbml.xml
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LIF1CH0PD1_sbml.xml
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<?xml version="1.0" encoding="UTF-8"?>
<!-- Created by BioNetGen 2.3.1 -->
<sbml xmlns="http://www.sbml.org/sbml/level2/version3" level="2" version="3">
<model id="mESC_generatingSBML">
<listOfCompartments>
<compartment id="cell" size="1"/>
</listOfCompartments>
<listOfSpecies>
<species id="S1" compartment="cell" initialConcentration="1" name="STAT3(b,b,nA~0,nR~0)"/>
<species id="S2" compartment="cell" initialConcentration="1" name="GBX2(b,b,nA~0,nR~0)"/>
<species id="S3" compartment="cell" initialConcentration="1" name="KLF4(b,b,nA~0,nR~0)"/>
<species id="S4" compartment="cell" initialConcentration="1" name="KLF2(b,b,nA~0,nR~0)"/>
<species id="S5" compartment="cell" initialConcentration="1" name="SALL4(b,b,nA~0,nR~0)"/>
<species id="S6" compartment="cell" initialConcentration="1" name="OCT4(b,b,nA~0,nR~0)"/>
<species id="S7" compartment="cell" initialConcentration="1" name="SOX2(b,b,nA~0,nR~0)"/>
<species id="S8" compartment="cell" initialConcentration="1" name="NANOG(b,b,nA~0,nR~0)"/>
<species id="S9" compartment="cell" initialConcentration="1" name="ESRRB(b,b,nA~0,nR~0)"/>
<species id="S10" compartment="cell" initialConcentration="1" name="TFCP2L1(b,b,nA~0,nR~0)"/>
<species id="S11" compartment="cell" initialConcentration="1" name="TCF3(b,b,nA~0,nR~0)"/>
<species id="S12" compartment="cell" initialConcentration="1" name="MEKERK(b,b,nA~0,nR~0)"/>
<species id="S13" compartment="cell" initialConcentration="0" name="stat3(s)"/>
<species id="S14" compartment="cell" initialConcentration="0" name="gbx2(s)"/>
<species id="S15" compartment="cell" initialConcentration="0" name="klf4(s)"/>
<species id="S16" compartment="cell" initialConcentration="0" name="klf2(s)"/>
<species id="S17" compartment="cell" initialConcentration="0" name="sall4(s)"/>
<species id="S18" compartment="cell" initialConcentration="0" name="oct4(s)"/>
<species id="S19" compartment="cell" initialConcentration="0" name="sox2(s)"/>
<species id="S20" compartment="cell" initialConcentration="0" name="nanog(s)"/>
<species id="S21" compartment="cell" initialConcentration="0" name="esrrb(s)"/>
<species id="S22" compartment="cell" initialConcentration="0" name="tfcp2l1(s)"/>
<species id="S23" compartment="cell" initialConcentration="0" name="tcf3(s)"/>
<species id="S24" compartment="cell" initialConcentration="0" name="mekerk(s)"/>
<species id="S25" compartment="cell" initialConcentration="0" name="lif(s)"/>
<species id="S26" compartment="cell" initialConcentration="0" name="ch(s)"/>
<species id="S27" compartment="cell" initialConcentration="0" name="pd(s)"/>
<species id="S28" compartment="cell" initialConcentration="0" name="STAT3(b!1,b,nA~1,nR~0).lif(s!1)"/>
<species id="S29" compartment="cell" initialConcentration="0" name="TCF3(b!1,b,nA~0,nR~1).ch(s!1)"/>
<species id="S30" compartment="cell" initialConcentration="0" name="MEKERK(b!1,b,nA~0,nR~1).pd(s!1)"/>
<species id="S31" compartment="cell" initialConcentration="0" name="GBX2(b!1,b,nA~1,nR~0).stat3(s!1)"/>
<species id="S32" compartment="cell" initialConcentration="0" name="KLF4(b!1,b,nA~1,nR~0).stat3(s!1)"/>
<species id="S33" compartment="cell" initialConcentration="0" name="TFCP2L1(b!1,b,nA~1,nR~0).stat3(s!1)"/>
<species id="S34" compartment="cell" initialConcentration="0" name="KLF4(b!1,b,nA~1,nR~0).gbx2(s!1)"/>
<species id="S35" compartment="cell" initialConcentration="0" name="KLF2(b!1,b,nA~1,nR~0).klf4(s!1)"/>
<species id="S36" compartment="cell" initialConcentration="0" name="SALL4(b!1,b,nA~1,nR~0).tfcp2l1(s!1)"/>
<species id="S37" compartment="cell" initialConcentration="0" name="KLF2(b!1,b,nA~1,nR~0).sall4(s!1)"/>
<species id="S38" compartment="cell" initialConcentration="0" name="OCT4(b!1,b,nA~1,nR~0).klf2(s!1)"/>
<species id="S39" compartment="cell" initialConcentration="0" name="TFCP2L1(b!1,b,nA~1,nR~0).klf4(s!1)"/>
<species id="S40" compartment="cell" initialConcentration="0" name="NANOG(b!1,b,nA~1,nR~0).klf2(s!1)"/>
<species id="S41" compartment="cell" initialConcentration="0" name="SOX2(b!1,b,nA~1,nR~0).sall4(s!1)"/>
<species id="S42" compartment="cell" initialConcentration="0" name="OCT4(b!1,b,nA~1,nR~0).sox2(s!1)"/>
<species id="S43" compartment="cell" initialConcentration="0" name="NANOG(b!1,b,nA~1,nR~0).oct4(s!1)"/>
<species id="S44" compartment="cell" initialConcentration="0" name="ESRRB(b!1,b,nA~1,nR~0).nanog(s!1)"/>
<species id="S45" compartment="cell" initialConcentration="0" name="SOX2(b!1,b,nA~1,nR~0).nanog(s!1)"/>
<species id="S46" compartment="cell" initialConcentration="0" name="ESRRB(b!1,b,nA~1,nR~0).tfcp2l1(s!1)"/>
<species id="S47" compartment="cell" initialConcentration="0" name="TCF3(b!1,b,nA~0,nR~1).mekerk(s!1)"/>
<species id="S48" compartment="cell" initialConcentration="0" name="NANOG(b!1,b,nA~0,nR~1).mekerk(s!1)"/>
<species id="S49" compartment="cell" initialConcentration="0" name="TFCP2L1(b!1,b,nA~0,nR~1).tcf3(s!1)"/>
<species id="S50" compartment="cell" initialConcentration="0" name="ESRRB(b!1,b,nA~0,nR~1).tcf3(s!1)"/>
<species id="S51" compartment="cell" initialConcentration="0" name="OCT4(b!1,b,nA~0,nR~1).esrrb(s!1)"/>
<species id="S52" compartment="cell" initialConcentration="0" name="TFCP2L1(b!1,b,nA~0,nR~1).oct4(s!1)"/>
<species id="S53" compartment="cell" initialConcentration="0" name="STAT3(b!1,b!2,nA~2,nR~0).lif(s!2).lif(s!1)"/>
<species id="S54" compartment="cell" initialConcentration="0" name="TCF3(b!1,b!2,nA~0,nR~2).ch(s!2).ch(s!1)"/>
<species id="S55" compartment="cell" initialConcentration="0" name="TCF3(b!1,b!2,nA~0,nR~2).ch(s!2).mekerk(s!1)"/>
<species id="S56" compartment="cell" initialConcentration="0" name="MEKERK(b!1,b!2,nA~0,nR~2).pd(s!2).pd(s!1)"/>
<species id="S57" compartment="cell" initialConcentration="0" name="GBX2(b!1,b!2,nA~2,nR~0).stat3(s!2).stat3(s!1)"/>
<species id="S58" compartment="cell" initialConcentration="0" name="KLF4(b!1,b!2,nA~2,nR~0).stat3(s!2).stat3(s!1)"/>
<species id="S59" compartment="cell" initialConcentration="0" name="KLF4(b!1,b!2,nA~2,nR~0).gbx2(s!1).stat3(s!2)"/>
<species id="S60" compartment="cell" initialConcentration="0" name="TFCP2L1(b!1,b!2,nA~1,nR~1).stat3(s!2).tcf3(s!1)"/>
<species id="S61" compartment="cell" initialConcentration="0" name="TFCP2L1(b!1,b!2,nA~1,nR~1).oct4(s!1).stat3(s!2)"/>
<species id="S62" compartment="cell" initialConcentration="0" name="TFCP2L1(b!1,b!2,nA~2,nR~0).stat3(s!2).stat3(s!1)"/>
<species id="S63" compartment="cell" initialConcentration="0" name="TFCP2L1(b!1,b!2,nA~2,nR~0).klf4(s!1).stat3(s!2)"/>
<species id="S64" compartment="cell" initialConcentration="0" name="KLF4(b!1,b!2,nA~2,nR~0).gbx2(s!2).gbx2(s!1)"/>
<species id="S65" compartment="cell" initialConcentration="0" name="KLF2(b!1,b!2,nA~2,nR~0).klf4(s!2).klf4(s!1)"/>
<species id="S66" compartment="cell" initialConcentration="0" name="KLF2(b!1,b!2,nA~2,nR~0).klf4(s!2).sall4(s!1)"/>
<species id="S67" compartment="cell" initialConcentration="0" name="SALL4(b!1,b!2,nA~2,nR~0).tfcp2l1(s!2).tfcp2l1(s!1)"/>
<species id="S68" compartment="cell" initialConcentration="0" name="KLF2(b!1,b!2,nA~2,nR~0).sall4(s!2).sall4(s!1)"/>
<species id="S69" compartment="cell" initialConcentration="0" name="OCT4(b!1,b!2,nA~1,nR~1).esrrb(s!1).klf2(s!2)"/>
<species id="S70" compartment="cell" initialConcentration="0" name="OCT4(b!1,b!2,nA~2,nR~0).klf2(s!2).klf2(s!1)"/>
<species id="S71" compartment="cell" initialConcentration="0" name="OCT4(b!1,b!2,nA~2,nR~0).klf2(s!2).sox2(s!1)"/>
<species id="S72" compartment="cell" initialConcentration="0" name="TFCP2L1(b!1,b!2,nA~1,nR~1).klf4(s!2).tcf3(s!1)"/>
<species id="S73" compartment="cell" initialConcentration="0" name="TFCP2L1(b!1,b!2,nA~1,nR~1).klf4(s!2).oct4(s!1)"/>
<species id="S74" compartment="cell" initialConcentration="0" name="TFCP2L1(b!1,b!2,nA~2,nR~0).klf4(s!2).klf4(s!1)"/>
<species id="S75" compartment="cell" initialConcentration="0" name="NANOG(b!1,b!2,nA~1,nR~1).klf2(s!2).mekerk(s!1)"/>
<species id="S76" compartment="cell" initialConcentration="0" name="NANOG(b!1,b!2,nA~2,nR~0).klf2(s!2).klf2(s!1)"/>
<species id="S77" compartment="cell" initialConcentration="0" name="NANOG(b!1,b!2,nA~2,nR~0).klf2(s!2).oct4(s!1)"/>
<species id="S78" compartment="cell" initialConcentration="0" name="SOX2(b!1,b!2,nA~2,nR~0).sall4(s!2).sall4(s!1)"/>
<species id="S79" compartment="cell" initialConcentration="0" name="SOX2(b!1,b!2,nA~2,nR~0).nanog(s!1).sall4(s!2)"/>
<species id="S80" compartment="cell" initialConcentration="0" name="OCT4(b!1,b!2,nA~1,nR~1).esrrb(s!1).sox2(s!2)"/>
<species id="S81" compartment="cell" initialConcentration="0" name="OCT4(b!1,b!2,nA~2,nR~0).sox2(s!2).sox2(s!1)"/>
<species id="S82" compartment="cell" initialConcentration="0" name="NANOG(b!1,b!2,nA~1,nR~1).mekerk(s!1).oct4(s!2)"/>
<species id="S83" compartment="cell" initialConcentration="0" name="NANOG(b!1,b!2,nA~2,nR~0).oct4(s!2).oct4(s!1)"/>
<species id="S84" compartment="cell" initialConcentration="0" name="ESRRB(b!1,b!2,nA~1,nR~1).nanog(s!2).tcf3(s!1)"/>
<species id="S85" compartment="cell" initialConcentration="0" name="ESRRB(b!1,b!2,nA~2,nR~0).nanog(s!2).nanog(s!1)"/>
<species id="S86" compartment="cell" initialConcentration="0" name="ESRRB(b!1,b!2,nA~2,nR~0).nanog(s!2).tfcp2l1(s!1)"/>
<species id="S87" compartment="cell" initialConcentration="0" name="SOX2(b!1,b!2,nA~2,nR~0).nanog(s!2).nanog(s!1)"/>
<species id="S88" compartment="cell" initialConcentration="0" name="ESRRB(b!1,b!2,nA~1,nR~1).tcf3(s!1).tfcp2l1(s!2)"/>
<species id="S89" compartment="cell" initialConcentration="0" name="ESRRB(b!1,b!2,nA~2,nR~0).tfcp2l1(s!2).tfcp2l1(s!1)"/>
<species id="S90" compartment="cell" initialConcentration="0" name="TCF3(b!1,b!2,nA~0,nR~2).mekerk(s!2).mekerk(s!1)"/>
<species id="S91" compartment="cell" initialConcentration="0" name="NANOG(b!1,b!2,nA~0,nR~2).mekerk(s!2).mekerk(s!1)"/>
<species id="S92" compartment="cell" initialConcentration="0" name="TFCP2L1(b!1,b!2,nA~0,nR~2).tcf3(s!2).tcf3(s!1)"/>
<species id="S93" compartment="cell" initialConcentration="0" name="TFCP2L1(b!1,b!2,nA~0,nR~2).oct4(s!1).tcf3(s!2)"/>
<species id="S94" compartment="cell" initialConcentration="0" name="ESRRB(b!1,b!2,nA~0,nR~2).tcf3(s!2).tcf3(s!1)"/>
<species id="S95" compartment="cell" initialConcentration="0" name="OCT4(b!1,b!2,nA~0,nR~2).esrrb(s!2).esrrb(s!1)"/>
<species id="S96" compartment="cell" initialConcentration="0" name="TFCP2L1(b!1,b!2,nA~0,nR~2).oct4(s!2).oct4(s!1)"/>
</listOfSpecies>
<listOfParameters>
<!-- Independent variables -->
<parameter id="Omega" value="10000"/>
<parameter id="gamma" value="1"/>
<parameter id="LIF" value="10000"/>
<parameter id="CH" value="0"/>
<parameter id="PD" value="10000"/>
<parameter id="kon" value="16"/>
<parameter id="koff" value="1.5"/>
<parameter id="alphamax" value="1"/>
<parameter id="alpham" value="0.01"/>
<parameter id="_rateLaw1" value="0"/>
<parameter id="_rateLaw2" value="0"/>
<parameter id="_rateLaw3" value="0"/>
<parameter id="_rateLaw4" value="0"/>
<parameter id="_rateLaw5" value="0"/>
<parameter id="_rateLaw6" value="0"/>
<parameter id="_rateLaw7" value="0"/>
<parameter id="_rateLaw8" value="0"/>
<parameter id="_rateLaw9" value="0"/>
<parameter id="_rateLaw10" value="0"/>
<parameter id="_rateLaw11" value="0"/>
<parameter id="_rateLaw12" value="0"/>
<parameter id="_rateLaw13" value="0"/>
<parameter id="_rateLaw14" value="0"/>
<parameter id="_rateLaw15" value="0"/>
<parameter id="_rateLaw16" value="0"/>
<parameter id="_rateLaw17" value="0"/>
<parameter id="_rateLaw18" value="0"/>
<!-- Dependent variables -->
<parameter id="konIB" constant="true"/>
<parameter id="koffIB" constant="true"/>
<parameter id="alphamIB" constant="true"/>
<parameter id="alphamaxIB" constant="true"/>
<parameter id="LIFIB" constant="true"/>
<parameter id="CHIB" constant="true"/>
<parameter id="PDIB" constant="true"/>
<!-- Observables -->
<parameter id="lif" constant="false"/>
<parameter id="ch" constant="false"/>
<parameter id="pd" constant="false"/>
<parameter id="stat3" constant="false"/>
<parameter id="gbx2" constant="false"/>
<parameter id="klf4" constant="false"/>
<parameter id="klf2" constant="false"/>
<parameter id="sall4" constant="false"/>
<parameter id="oct4" constant="false"/>
<parameter id="sox2" constant="false"/>
<parameter id="nanog" constant="false"/>
<parameter id="esrrb" constant="false"/>
<parameter id="tfcp2l1" constant="false"/>
<parameter id="tcf3" constant="false"/>
<parameter id="mekerk" constant="false"/>
</listOfParameters>
<listOfInitialAssignments>
<!-- Dependent variables -->
<initialAssignment symbol="konIB">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<divide/>
<ci> kon </ci>
<ci> Omega </ci>
</apply>
</math>
</initialAssignment>
<initialAssignment symbol="koffIB">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<ci> koff </ci>
</math>
</initialAssignment>
<initialAssignment symbol="alphamIB">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> alpham </ci>
<ci> Omega </ci>
</apply>
</math>
</initialAssignment>
<initialAssignment symbol="alphamaxIB">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> alphamax </ci>
<ci> Omega </ci>
</apply>
</math>
</initialAssignment>
<initialAssignment symbol="LIFIB">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> LIF </ci>
<ci> Omega </ci>
</apply>
</math>
</initialAssignment>
<initialAssignment symbol="CHIB">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> CH </ci>
<ci> Omega </ci>
</apply>
</math>
</initialAssignment>
<initialAssignment symbol="PDIB">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> PD </ci>
<ci> Omega </ci>
</apply>
</math>
</initialAssignment>
</listOfInitialAssignments>
<listOfRules>
<!-- Observables -->
<assignmentRule variable="lif">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<plus/>
<cn> 0 </cn>
<ci> S25 </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable="ch">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<plus/>
<cn> 0 </cn>
<ci> S26 </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable="pd">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<plus/>
<cn> 0 </cn>
<ci> S27 </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable="stat3">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<plus/>
<cn> 0 </cn>
<ci> S13 </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable="gbx2">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<plus/>
<cn> 0 </cn>
<ci> S14 </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable="klf4">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<plus/>
<cn> 0 </cn>
<ci> S15 </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable="klf2">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<plus/>
<cn> 0 </cn>
<ci> S16 </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable="sall4">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<plus/>
<cn> 0 </cn>
<ci> S17 </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable="oct4">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<plus/>
<cn> 0 </cn>
<ci> S18 </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable="sox2">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<plus/>
<cn> 0 </cn>
<ci> S19 </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable="nanog">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<plus/>
<cn> 0 </cn>
<ci> S20 </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable="esrrb">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<plus/>
<cn> 0 </cn>
<ci> S21 </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable="tfcp2l1">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<plus/>
<cn> 0 </cn>
<ci> S22 </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable="tcf3">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<plus/>
<cn> 0 </cn>
<ci> S23 </ci>
</apply>
</math>
</assignmentRule>
<assignmentRule variable="mekerk">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<plus/>
<cn> 0 </cn>
<ci> S24 </ci>
</apply>
</math>
</assignmentRule>
</listOfRules>
<listOfReactions>
<reaction id="R1" reversible="false">
<listOfProducts>
<speciesReference species="S25"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> LIFIB </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R2" reversible="false">
<listOfReactants>
<speciesReference species="S25"/>
</listOfReactants>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> gamma </ci>
<ci> S25 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R3" reversible="false">
<listOfProducts>
<speciesReference species="S26"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> CHIB </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R4" reversible="false">
<listOfReactants>
<speciesReference species="S26"/>
</listOfReactants>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> gamma </ci>
<ci> S26 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R5" reversible="false">
<listOfProducts>
<speciesReference species="S27"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> PDIB </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R6" reversible="false">
<listOfReactants>
<speciesReference species="S27"/>
</listOfReactants>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> gamma </ci>
<ci> S27 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R7" reversible="false">
<listOfReactants>
<speciesReference species="S1"/>
<speciesReference species="S25"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S28"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S1 </ci>
<ci> S25 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R8" reversible="false">
<listOfReactants>
<speciesReference species="S11"/>
<speciesReference species="S26"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S29"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S11 </ci>
<ci> S26 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R9" reversible="false">
<listOfReactants>
<speciesReference species="S12"/>
<speciesReference species="S27"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S30"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S12 </ci>
<ci> S27 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R10" reversible="false">
<listOfReactants>
<speciesReference species="S2"/>
<speciesReference species="S13"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S31"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S2 </ci>
<ci> S13 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R11" reversible="false">
<listOfReactants>
<speciesReference species="S3"/>
<speciesReference species="S13"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S32"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S3 </ci>
<ci> S13 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R12" reversible="false">
<listOfReactants>
<speciesReference species="S10"/>
<speciesReference species="S13"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S33"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S10 </ci>
<ci> S13 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R13" reversible="false">
<listOfReactants>
<speciesReference species="S3"/>
<speciesReference species="S14"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S34"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S3 </ci>
<ci> S14 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R14" reversible="false">
<listOfReactants>
<speciesReference species="S4"/>
<speciesReference species="S15"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S35"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S4 </ci>
<ci> S15 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R15" reversible="false">
<listOfReactants>
<speciesReference species="S5"/>
<speciesReference species="S22"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S36"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S5 </ci>
<ci> S22 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R16" reversible="false">
<listOfReactants>
<speciesReference species="S4"/>
<speciesReference species="S17"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S37"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S4 </ci>
<ci> S17 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R17" reversible="false">
<listOfReactants>
<speciesReference species="S6"/>
<speciesReference species="S16"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S38"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S6 </ci>
<ci> S16 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R18" reversible="false">
<listOfReactants>
<speciesReference species="S10"/>
<speciesReference species="S15"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S39"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S10 </ci>
<ci> S15 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R19" reversible="false">
<listOfReactants>
<speciesReference species="S8"/>
<speciesReference species="S16"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S40"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S8 </ci>
<ci> S16 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R20" reversible="false">
<listOfReactants>
<speciesReference species="S7"/>
<speciesReference species="S17"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S41"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S7 </ci>
<ci> S17 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R21" reversible="false">
<listOfReactants>
<speciesReference species="S6"/>
<speciesReference species="S19"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S42"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S6 </ci>
<ci> S19 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R22" reversible="false">
<listOfReactants>
<speciesReference species="S8"/>
<speciesReference species="S18"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S43"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S8 </ci>
<ci> S18 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R23" reversible="false">
<listOfReactants>
<speciesReference species="S9"/>
<speciesReference species="S20"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S44"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S9 </ci>
<ci> S20 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R24" reversible="false">
<listOfReactants>
<speciesReference species="S7"/>
<speciesReference species="S20"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S45"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S7 </ci>
<ci> S20 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R25" reversible="false">
<listOfReactants>
<speciesReference species="S10"/>
<speciesReference species="S21"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S33"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S10 </ci>
<ci> S21 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R26" reversible="false">
<listOfReactants>
<speciesReference species="S9"/>
<speciesReference species="S22"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S46"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S9 </ci>
<ci> S22 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R27" reversible="false">
<listOfReactants>
<speciesReference species="S11"/>
<speciesReference species="S24"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S47"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S11 </ci>
<ci> S24 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R28" reversible="false">
<listOfReactants>
<speciesReference species="S8"/>
<speciesReference species="S24"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S48"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S8 </ci>
<ci> S24 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R29" reversible="false">
<listOfReactants>
<speciesReference species="S10"/>
<speciesReference species="S23"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S49"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S10 </ci>
<ci> S23 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R30" reversible="false">
<listOfReactants>
<speciesReference species="S9"/>
<speciesReference species="S23"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S50"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S9 </ci>
<ci> S23 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R31" reversible="false">
<listOfReactants>
<speciesReference species="S6"/>
<speciesReference species="S21"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S51"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S6 </ci>
<ci> S21 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R32" reversible="false">
<listOfReactants>
<speciesReference species="S10"/>
<speciesReference species="S18"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S52"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<cn> 2 </cn>
<ci> konIB </ci>
<ci> S10 </ci>
<ci> S18 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R33" reversible="false">
<listOfReactants>
<speciesReference species="S1"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S1"/>
<speciesReference species="S13"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> _rateLaw2 </ci>
<ci> S1 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R34" reversible="false">
<listOfReactants>
<speciesReference species="S2"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="S2"/>
<speciesReference species="S14"/>
</listOfProducts>
<kineticLaw>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> _rateLaw4 </ci>
<ci> S2 </ci>
</apply>
</math>
</kineticLaw>
</reaction>
<reaction id="R35" reversible="false">
<listOfReactants>
<speciesReference species="S3"/>