Merge pull request #768 from SysBioChalmers/fix/linolenoyl_beta_oxida…

…tion Remove Duplicate Linolenoyl-CoA Beta-Oxidation Reactions
SysBioChalmers · Dec 18, 2023 · 04a85be · 04a85be
2 parents cee575c + f4a32e0
commit 04a85be
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Showing 3 changed files with 20 additions and 67 deletions.
diff --git a/data/deprecatedIdentifiers/deprecatedReactions.tsv b/data/deprecatedIdentifiers/deprecatedReactions.tsv
@@ -269,3 +269,5 @@ rxns	rxnKEGGID	rxnBiGGID	rxnEHMNID	rxnHepatoNET1ID	rxnREACTOMEID	rxnRecon3DID	rx
 "MAR03422"	""	""	""	""	""	"HMR_3422"	""	"HMR_3422"	"RCR12667"	""	0	""	""	"HMR_3422"
 "MAR03748"	"R01210"	"OIVD2m"	"R03171M"	"r0600"	""	"OIVD2m"	"MNXR102173;MNXR107999"	"HMR_3748"	"RCR14420"	""	0	""	"RHEA:13997"	"HMR_3748"
 "MAR03780"	"R03171"	"OIVD3m"	"R03171M"	"r0602"	""	"OIVD3m"	"MNXR102174;MNXR107999"	"HMR_3780"	"RCR10345"	""	0	""	"RHEA:30907"	"HMR_3780"
+"MAR00789"	""	"FAOXC183803m"	""	""	""	"FAOXC183803m"	"MNXR99325"	""	""	""	0	""	""	"FAOXC183803m"
+"MAR03426"	""	"HMR_3426"	""	""	""	"HMR_3426"	""	"HMR_3426"	"RCR12671"	""	0	""	""	"HMR_3426"
diff --git a/model/Human-GEM.yml b/model/Human-GEM.yml
@@ -119159,29 +119159,6 @@
       - subsystem:
           - "Beta oxidation of even-chain fatty acids (mitochondrial)"
       - confidence_score: 0
-    - !!omap
-      - id: "MAR03426"
-      - name: ""
-      - metabolites: !!omap
-          - MAM01261m: 9
-          - MAM01597m: -8
-          - MAM01802m: -5
-          - MAM01803m: 5
-          - MAM02039m: 8
-          - MAM02040m: -8
-          - MAM02390m: -1
-          - MAM02552m: -8
-          - MAM02553m: 8
-      - lower_bound: 0
-      - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000060971 or ENSG00000072506 or ENSG00000072778 or ENSG00000084754 or ENSG00000115361 or ENSG00000117054 or ENSG00000127884 or ENSG00000138029 or ENSG00000138796 or ENSG00000167315 or ENSG00000177646"
-      - rxnNotes: ""
-      - rxnFrom: "HMRdatabase"
-      - eccodes: "4.2.1.17;1.1.1.35;1.1.1.211;1.3.8.7;1.3.8.8;1.3.8.9;2.3.1.16"
-      - references: ""
-      - subsystem:
-          - "Beta oxidation of even-chain fatty acids (mitochondrial)"
-      - confidence_score: 0
     - !!omap
       - id: "MAR09719"
       - name: ""
@@ -221754,30 +221731,6 @@
       - subsystem:
           - "Fatty acid oxidation"
       - confidence_score: 0
-    - !!omap
-      - id: "MAR00789"
-      - name: "Beta Oxidation of Fatty Acid"
-      - metabolites: !!omap
-          - MAM01261m: 5
-          - MAM01597m: -5
-          - MAM01802m: -2
-          - MAM01803m: 2
-          - MAM02039m: 5
-          - MAM02040m: -5
-          - MAM02390m: -1
-          - MAM02552m: -5
-          - MAM02553m: 5
-          - MAM02644m: 1
-      - lower_bound: 0
-      - upper_bound: 1000
-      - gene_reaction_rule: "ENSG00000117054 or ENSG00000122971"
-      - rxnNotes: ""
-      - rxnFrom: "Recon3D"
-      - eccodes: "4.2.1.74"
-      - references: ""
-      - subsystem:
-          - "Fatty acid oxidation"
-      - confidence_score: 0
     - !!omap
       - id: "MAR00799"
       - name: "Beta Oxidation of Fatty Acid"

diff --git a/model/reactions.tsv b/model/reactions.tsv
@@ -178,7 +178,7 @@ rxns	rxnKEGGID	rxnBiGGID	rxnEHMNID	rxnHepatoNET1ID	rxnREACTOMEID	rxnRecon3DID	rx
 "MAR00719"	"R08198"	""	""	""	""	"HMR_0719"	"MNXR111769"	"HMR_0719"	"RCR11097"	""	0	""	"RHEA:13449"	"HMR_0719"
 "MAR01434"	"R00238"	"ACACT1r"	"R00238M"	"r0069"	""	"ACACT1r"	"MNXR95194"	"HMR_1434"	"RCR10465"	""	0	"RHEA:21039"	"RHEA:21036"	"HMR_1434"
 "MAR01436"	"R01357"	"AACOAT"	"R01357M"	"r0320"	""	"AACOAT"	"MNXR95136"	"HMR_1436"	"RCR10466"	""	0	"RHEA:16118"	"RHEA:16117"	"HMR_1436"
-"MAR03163"	"R01175"	"ACOAD1fm"	""	""	"R-HSA-77319"	"ACOAD1fm;HMR_3422"	"MNXR95302"	"HMR_3163;HMR_3422"	"RCR11098;RCR12667"	""	0	""	"RHEA:24004"	"HMR_3163;HMR_3422;MAR03422"
+"MAR03163"	"R01175"	"ACOAD1fm;HMR_3426"	""	""	"R-HSA-77319"	"ACOAD1fm;HMR_3422;HMR_3426"	"MNXR95302"	"HMR_3163;HMR_3422;HMR_3426"	"RCR11098;RCR12667;RCR12671"	""	0	""	"RHEA:24004"	"HMR_3163;HMR_3422;MAR03422;HMR_3426;MAR03426"
 "MAR04461"	"R01361"	"BDHm"	"R01361C"	"r0323"	""	"BDHm"	"MNXR96232"	"HMR_4461"	"RCR10467"	""	0	"RHEA:20524"	"RHEA:20521"	"HMR_4461"
 "MAR04604"	"R01978"	""	"R01978C"	"r0463"	""	"r0463"	"MNXR100660;MNXR107257"	"HMR_4604"	"RCR11099"	""	0	""	"RHEA:10188"	"HMR_4604"
 "MAR05351"	"R01000"	""	""	""	""	"2HBO"	"MNXR94796"	"HMR_5351"	"RCR10152"	""	0	""	"RHEA:36371"	"HMR_5351"
@@ -740,9 +740,9 @@ rxns	rxnKEGGID	rxnBiGGID	rxnEHMNID	rxnHepatoNET1ID	rxnREACTOMEID	rxnRecon3DID	rx
 "MAR08026"	""	"LYSMTF2n"	""	""	""	"LYSMTF2n"	"MNXR101260"	"HMR_8026"	"RCR11349"	""	0	""	""	"HMR_8026"
 "MAR08027"	"R04867"	"LYSMTF3n"	""	""	""	"LYSMTF3n"	"MNXR101261"	"HMR_8027"	"RCR11350"	""	0	""	"RHEA:54200"	"HMR_8027"
 "MAR08029"	""	"PLYSPSer"	""	""	""	"PLYSPSer"	"MNXR103039"	"HMR_8029"	"RCR14338"	""	0	""	""	"HMR_8029"
-"MAR03164"	"R03026"	"ECOAH1m"	"R03026M"	"r0588"	""	"ECOAH1m;HMR_3422"	"MNXR97883"	"HMR_3164;HMR_3422"	"RCR11351;RCR12667"	""	0	""	"RHEA:26558"	"HMR_3164;HMR_3422;MAR03422"
-"MAR03166"	"R01975"	"HACD1m"	"R01975M"	"r0460"	""	"HACD1m;HMR_3422"	"MNXR100541"	"HMR_3166;HMR_3422"	"RCR11352;RCR12667"	""	0	""	"RHEA:30799"	"HMR_3166;HMR_3422;MAR03422"
-"MAR03885"	"R00238"	"ACACT1m"	"R00238M"	"r0070"	""	"ACACT1rm;HMR_3422"	"MNXR95194"	"HMR_3885;HMR_3422"	"RCR10247;RCR12667"	""	0	"RHEA:21039"	"RHEA:21036"	"HMR_3885;HMR_3422;MAR03422"
+"MAR03164"	"R03026"	"ECOAH1m;HMR_3426"	"R03026M"	"r0588"	""	"ECOAH1m;HMR_3422;HMR_3426"	"MNXR97883"	"HMR_3164;HMR_3422;HMR_3426"	"RCR11351;RCR12667;RCR12671"	""	0	""	"RHEA:26558"	"HMR_3164;HMR_3422;MAR03422;HMR_3426;MAR03426"
+"MAR03166"	"R01975"	"HACD1m;HMR_3426"	"R01975M"	"r0460"	""	"HACD1m;HMR_3422;HMR_3426"	"MNXR100541"	"HMR_3166;HMR_3422;HMR_3426"	"RCR11352;RCR12667;RCR12671"	""	0	""	"RHEA:30799"	"HMR_3166;HMR_3422;MAR03422;HMR_3426;MAR03426"
+"MAR03885"	"R00238"	"ACACT1m;HMR_3426"	"R00238M"	"r0070"	""	"ACACT1rm;HMR_3422;HMR_3426"	"MNXR95194"	"HMR_3885;HMR_3422;HMR_3426"	"RCR10247;RCR12667;RCR12671"	""	0	"RHEA:21039"	"RHEA:21036"	"HMR_3885;HMR_3422;MAR03422;HMR_3426;MAR03426"
 "MAR04250"	"R04293"	"QUILSYN"	""	"r0675"	""	"QUILSYN"	"MNXR103396"	"HMR_4250"	"RCR11353"	""	1	""	"RHEA:25147"	"HMR_4250"
 "MAR08091"	""	"3HXKYNDCL"	""	""	""	"3HXKYNDCL"	"MNXR94906"	"HMR_8091"	"RCR11354"	""	0	""	""	"HMR_8091"
 "MAR08092"	"R04907"	"3HXKYNOXDA"	""	""	""	"3HXKYNOXDA"	"MNXR94907"	"HMR_8092"	"RCR11355"	""	0	""	""	"HMR_8092"
@@ -2652,9 +2652,9 @@ rxns	rxnKEGGID	rxnBiGGID	rxnEHMNID	rxnHepatoNET1ID	rxnREACTOMEID	rxnRecon3DID	rx
 "MAR03151"	"R04745"	""	"R04745M"	"r0730"	""	"r0730;HMR_3422"	"MNXR100544"	"HMR_3151;HMR_3422"	"RCR12651;RCR12667"	""	0	""	"RHEA:31195"	"HMR_3151;HMR_3422;MAR03422"
 "MAR03153"	"R04747"	""	"R04747M"	"r0732"	""	"r0732;HMR_3422"	"MNXR109092"	"HMR_3153;HMR_3422"	"RCR12652;RCR12667"	""	0	"RHEA:31205"	"RHEA:31203"	"HMR_3153;HMR_3422;MAR03422"
 "MAR03156"	"R04751"	"r1450"	""	""	"R-HSA-77327"	"HMR_3156;r1450;HMR_3422"	"MNXR109093"	"HMR_3156;HMR_3422"	"RCR12653;RCR12667"	""	0	""	"RHEA:31207"	"HMR_3156;r1450;MAR02372;HMR_3422;MAR03422"
-"MAR03157"	"R04749"	""	"R04749M"	"r0734"	""	"r0734;HMR_3422"	"MNXR97886"	"HMR_3157;HMR_3422"	"RCR12654;RCR12667"	""	0	""	"RHEA:30547"	"HMR_3157;HMR_3422;MAR03422"
-"MAR03158"	"R04748"	""	"R04748M"	"r0733"	"R-HSA-77323"	"r0733;HMR_3422"	"MNXR100543"	"HMR_3158;HMR_3422"	"RCR12655;RCR12667"	""	0	""	"RHEA:31143"	"HMR_3158;HMR_3422;MAR03422"
-"MAR03160"	"R01177"	""	"R01177M"	"r0287"	"R-HSA-77321"	"r0287;HMR_3422"	"MNXR95196"	"HMR_3160;HMR_3422"	"RCR12656;RCR12667"	""	0	""	"RHEA:31111"	"HMR_3160;HMR_3422;MAR03422"
+"MAR03157"	"R04749"	"HMR_3426"	"R04749M"	"r0734"	""	"r0734;HMR_3422;HMR_3426"	"MNXR97886"	"HMR_3157;HMR_3422;HMR_3426"	"RCR12654;RCR12667;RCR12671"	""	0	""	"RHEA:30547"	"HMR_3157;HMR_3422;MAR03422;HMR_3426;MAR03426"
+"MAR03158"	"R04748"	"HMR_3426"	"R04748M"	"r0733"	"R-HSA-77323"	"r0733;HMR_3422;HMR_3426"	"MNXR100543"	"HMR_3158;HMR_3422;HMR_3426"	"RCR12655;RCR12667;RCR12671"	""	0	""	"RHEA:31143"	"HMR_3158;HMR_3422;MAR03422;HMR_3426;MAR03426"
+"MAR03160"	"R01177"	"HMR_3426"	"R01177M"	"r0287"	"R-HSA-77321"	"r0287;HMR_3422;HMR_3426"	"MNXR95196"	"HMR_3160;HMR_3422;HMR_3426"	"RCR12656;RCR12667;RCR12671"	""	0	""	"RHEA:31111"	"HMR_3160;HMR_3422;MAR03422;HMR_3426;MAR03426"
 "MAR03398"	""	"HMR_3398"	""	""	""	"HMR_3398"	""	"HMR_3398"	"RCR12657"	""	0	""	""	"HMR_3398"
 "MAR03406"	""	"HMR_3406"	""	""	""	"HMR_3406"	""	"HMR_3406"	"RCR12658"	""	0	""	""	"HMR_3406"
 "MAR03407"	""	""	""	""	""	"HMR_3407"	""	"HMR_3407"	"RCR12659"	""	0	""	""	"HMR_3407"
@@ -2668,7 +2668,6 @@ rxns	rxnKEGGID	rxnBiGGID	rxnEHMNID	rxnHepatoNET1ID	rxnREACTOMEID	rxnRecon3DID	rx
 "MAR03423"	""	"HMR_3423"	""	""	""	"HMR_3423"	""	"HMR_3423"	"RCR12668"	""	0	""	""	"HMR_3423"
 "MAR03424"	""	""	""	""	""	"HMR_3424"	""	"HMR_3424"	"RCR12669"	""	0	""	""	"HMR_3424"
 "MAR03425"	""	""	""	""	""	"HMR_3425"	""	"HMR_3425"	"RCR12670"	""	0	""	""	"HMR_3425"
-"MAR03426"	""	"HMR_3426"	""	""	""	"HMR_3426"	""	"HMR_3426"	"RCR12671"	""	0	""	""	"HMR_3426"
 "MAR09719"	""	""	""	""	""	"HMR_9719"	""	"HMR_9719"	"RCR12672"	""	0	""	""	"HMR_9719"
 "MAR03427"	""	""	""	""	""	"HMR_3427"	""	"HMR_3427"	"RCR12673"	""	0	""	""	"HMR_3427"
 "MAR03428"	""	""	""	""	""	"HMR_3428"	""	"HMR_3428"	"RCR12674"	""	0	""	""	"HMR_3428"
@@ -8263,7 +8262,6 @@ rxns	rxnKEGGID	rxnBiGGID	rxnEHMNID	rxnHepatoNET1ID	rxnREACTOMEID	rxnRecon3DID	rx
 "MAR00784"	""	"FAOXC1811603m"	""	""	""	"FAOXC1811603m"	"MNXR99317"	""	""	""	0	""	""	"FAOXC1811603m"
 "MAR00785"	""	"FAOXC182806m"	""	""	""	"FAOXC182806m"	"MNXR99321"	""	""	""	0	""	""	"FAOXC182806m"
 "MAR00788"	""	"FAOXC18280m"	""	""	""	"FAOXC18280m"	"MNXR99322"	""	""	""	0	""	""	"FAOXC18280m"
-"MAR00789"	""	"FAOXC183803m"	""	""	""	"FAOXC183803m"	"MNXR99325"	""	""	""	0	""	""	"FAOXC183803m"
 "MAR00799"	""	"FAOXC183806m"	""	""	""	"FAOXC183806m"	"MNXR99326"	""	""	""	0	""	""	"FAOXC183806m"
 "MAR00800"	""	"FAOXC183806x"	""	""	""	"FAOXC183806x"	"MNXR99326"	""	""	""	0	""	""	"FAOXC183806x"
 "MAR00818"	""	"FAOXC18480m"	""	""	""	"FAOXC18480m"	"MNXR99330"	""	""	""	0	""	""	"FAOXC18480m"
@@ -9225,13 +9223,13 @@ rxns	rxnKEGGID	rxnBiGGID	rxnEHMNID	rxnHepatoNET1ID	rxnREACTOMEID	rxnRecon3DID	rx
 "MAR04968"	""	"FAOXC101C8x"	""	""	""	"FAOXC101C8x"	""	""	""	""	0	""	""	"FAOXC101C8x"
 "MAR04970"	""	"FAOXC102C101m"	""	""	""	"FAOXC102C101m;HMR_3422"	""	"HMR_3422"	"RCR12667"	""	0	""	""	"FAOXC102C101m;HMR_3422;MAR03422"
 "MAR04974"	""	"FAOXC102C101x"	""	""	""	"FAOXC102C101x"	""	""	""	""	0	""	""	"FAOXC102C101x"
-"MAR04978"	""	"FAOXC102C103m"	""	""	""	"FAOXC102C103m"	""	""	""	""	0	""	""	"FAOXC102C103m"
+"MAR04978"	""	"FAOXC102C103m;HMR_3426"	""	""	""	"FAOXC102C103m;HMR_3426"	""	"HMR_3426"	"RCR12671"	""	0	""	""	"FAOXC102C103m;HMR_3426;MAR03426"
 "MAR04981"	""	"FAOXC102C103x"	""	""	""	"FAOXC102C103x"	""	""	""	""	0	""	""	"FAOXC102C103x"
-"MAR04984"	""	"FAOXC102C81m"	""	""	""	"FAOXC102C81m"	""	""	""	""	0	""	""	"FAOXC102C81m"
+"MAR04984"	""	"FAOXC102C81m;HMR_3426"	""	""	""	"FAOXC102C81m;HMR_3426"	""	"HMR_3426"	"RCR12671"	""	0	""	""	"FAOXC102C81m;HMR_3426;MAR03426"
 "MAR04987"	""	"FAOXC102C81x"	""	""	""	"FAOXC102C81x"	""	""	""	""	0	""	""	"FAOXC102C81x"
-"MAR04988"	""	"FAOXC102m"	""	""	""	"FAOXC102m"	""	""	""	""	0	""	""	"FAOXC102m"
+"MAR04988"	""	"FAOXC102m;HMR_3426"	""	""	""	"FAOXC102m;HMR_3426"	""	"HMR_3426"	"RCR12671"	""	0	""	""	"FAOXC102m;HMR_3426;MAR03426"
 "MAR04991"	""	"FAOXC102x"	""	""	""	"FAOXC102x"	""	""	""	""	0	""	""	"FAOXC102x"
-"MAR05001"	""	"FAOXC103C102m"	""	""	""	"FAOXC103C102m"	""	""	""	""	0	""	""	"FAOXC103C102m"
+"MAR05001"	""	"FAOXC103C102m;HMR_3426"	""	""	""	"FAOXC103C102m;HMR_3426"	""	"HMR_3426"	"RCR12671"	""	0	""	""	"FAOXC103C102m;HMR_3426;MAR03426"
 "MAR05017"	""	"FAOXC103C102x"	""	""	""	"FAOXC103C102x"	""	""	""	""	0	""	""	"FAOXC103C102x"
 "MAR05019"	""	"FAOXC10C10OHm"	""	""	""	"FAOXC10C10OHm"	""	""	""	""	0	""	""	"FAOXC10C10OHm"
 "MAR05024"	""	"FAOXC10080m"	""	""	""	"FAOXC10C8m"	"MNXR99262"	""	""	""	0	""	""	"FAOXC10C8m"
@@ -9244,9 +9242,9 @@ rxns	rxnKEGGID	rxnBiGGID	rxnEHMNID	rxnHepatoNET1ID	rxnREACTOMEID	rxnRecon3DID	rx
 "MAR05072"	""	"FAOXC122C101m"	""	""	""	"FAOXC122C101m;HMR_3422"	""	"HMR_3422"	"RCR12667"	""	0	""	""	"FAOXC122C101m;HMR_3422;MAR03422"
 "MAR05075"	""	"FAOXC122m"	""	""	""	"FAOXC122m;HMR_3422"	""	"HMR_3422"	"RCR12667"	""	0	""	""	"FAOXC122m;HMR_3422;MAR03422"
 "MAR05081"	""	"FAOXC122x"	""	""	""	"FAOXC122x"	""	""	""	""	0	""	""	"FAOXC122x"
-"MAR05083"	""	"FAOXC123C102m"	""	""	""	"FAOXC123C102m"	""	""	""	""	0	""	""	"FAOXC123C102m"
+"MAR05083"	""	"FAOXC123C102m;HMR_3426"	""	""	""	"FAOXC123C102;HMR_3426m"	""	"HMR_3426"	"RCR12671"	""	0	""	""	"FAOXC123C102m;HMR_3426;MAR03426"
 "MAR05086"	""	"FAOXC123C102x"	""	""	""	"FAOXC123C102x"	""	""	""	""	0	""	""	"FAOXC123C102x"
-"MAR05090"	""	"FAOXC123m"	""	""	""	"FAOXC123m"	""	""	""	""	0	""	""	"FAOXC123m"
+"MAR05090"	""	"FAOXC123m;HMR_3426"	""	""	""	"FAOXC123m;HMR_3426"	""	"HMR_3426"	"RCR12671"	""	0	""	""	"FAOXC123m;HMR_3426;MAR03426"
 "MAR05093"	""	"FAOXC123x"	""	""	""	"FAOXC123x"	""	""	""	""	0	""	""	"FAOXC123x"
 "MAR05095"	""	"FAOXC120100m"	""	""	""	"FAOXC12C10m"	"MNXR99273"	""	""	""	0	""	""	"FAOXC12C10m"
 "MAR05097"	""	"FAOXC120100x"	""	""	""	"FAOXC12C10x"	"MNXR99274"	""	""	""	0	""	""	"FAOXC12C10x"
@@ -9263,7 +9261,7 @@ rxns	rxnKEGGID	rxnBiGGID	rxnEHMNID	rxnHepatoNET1ID	rxnREACTOMEID	rxnRecon3DID	rx
 "MAR05123"	""	"FAOXC142C122m"	""	""	""	"FAOXC142C122m;HMR_3422"	""	"HMR_3422"	"RCR12667"	""	0	""	""	"FAOXC142C122m;HMR_3422;MAR03422"
 "MAR05175"	""	"FAOXC142C122x"	""	""	""	"FAOXC142C122x"	""	""	""	""	0	""	""	"FAOXC142C122x"
 "MAR05176"	""	"FAOXC142C142OHm"	""	""	""	"FAOXC142C142OHm"	""	""	""	""	0	""	""	"FAOXC142C142OHm"
-"MAR05177"	""	"FAOXC143C123m"	""	""	""	"FAOXC143C123m"	""	""	""	""	0	""	""	"FAOXC143C123m"
+"MAR05177"	""	"FAOXC143C123m;HMR_3426"	""	""	""	"FAOXC143C123m;HMR_3426"	""	"HMR_3426"	"RCR12671"	""	0	""	""	"FAOXC143C123m;HMR_3426;MAR03426"
 "MAR05178"	""	"FAOXC143C123x"	""	""	""	"FAOXC143C123x"	""	""	""	""	0	""	""	"FAOXC143C123x"
 "MAR05179"	""	"FAOXC140120m"	""	""	""	"FAOXC14C12m"	"MNXR99282"	""	""	""	0	""	""	"FAOXC14C12m"
 "MAR05180"	""	"FAOXC140120x"	""	""	""	"FAOXC14C12x"	"MNXR99283"	""	""	""	0	""	""	"FAOXC14C12x"
@@ -9280,7 +9278,7 @@ rxns	rxnKEGGID	rxnBiGGID	rxnEHMNID	rxnHepatoNET1ID	rxnREACTOMEID	rxnRecon3DID	rx
 "MAR05191"	""	"FAOXC162C142m"	""	""	""	"FAOXC162C142m"	""	""	""	""	0	""	""	"FAOXC162C142m"
 "MAR05192"	""	"FAOXC162C162OHm"	""	""	""	"FAOXC162C162OHm"	""	""	""	""	0	""	""	"FAOXC162C162OHm"
 "MAR05193"	""	"FAOXC163C142x"	""	""	""	"FAOXC163C142x"	""	""	""	""	0	""	""	"FAOXC163C142x"
-"MAR05194"	""	"FAOXC163C143m"	""	""	""	"FAOXC163C143m"	""	""	""	""	0	""	""	"FAOXC163C143m"
+"MAR05194"	""	"FAOXC163C143m;HMR_3426"	""	""	""	"FAOXC163C143m;HMR_3426"	""	"HMR_3426"	"RCR12671"	""	0	""	""	"FAOXC163C143m;HMR_3426;MAR03426"
 "MAR05195"	""	"FAOXC163C164Gm"	""	""	""	"FAOXC163C164Gm;HMR_3422"	""	"HMR_3422"	"RCR12667"	""	0	""	""	"FAOXC163C164Gm;HMR_3422;MAR03422"
 "MAR05196"	""	"FAOXC163C164x"	""	""	""	"FAOXC163C164x"	""	""	""	""	0	""	""	"FAOXC163C164x"
 "MAR05208"	""	"FAOXC163GC142m"	""	""	""	"FAOXC163GC142m;HMR_3422"	""	"HMR_3422"	"RCR12667"	""	0	""	""	"FAOXC163GC142m;HMR_3422;MAR03422"
@@ -9309,7 +9307,7 @@ rxns	rxnKEGGID	rxnBiGGID	rxnEHMNID	rxnHepatoNET1ID	rxnREACTOMEID	rxnRecon3DID	rx
 "MAR05356"	""	"FAOXC182C162m"	""	""	""	"FAOXC182C162m"	""	""	""	""	0	""	""	"FAOXC182C162m"
 "MAR05357"	""	"FAOXC182C182OHm"	""	""	""	"FAOXC182C182OHm"	""	""	""	""	0	""	""	"FAOXC182C182OHm"
 "MAR05358"	""	"FAOXC183C163Gm"	""	""	""	"FAOXC183C163Gm"	""	""	""	""	0	""	""	"FAOXC183C163Gm"
-"MAR05359"	""	"FAOXC183C163m"	""	""	""	"FAOXC183C163m"	""	""	""	""	0	""	""	"FAOXC183C163m"
+"MAR05359"	""	"FAOXC183C163m;HMR_3426"	""	""	""	"FAOXC183C163m;HMR_3426"	""	"HMR_3426"	"RCR12671"	""	0	""	""	"FAOXC183C163m;HMR_3426;MAR03426"
 "MAR05360"	""	"FAOXC184C163m"	""	""	""	"FAOXC184C163m;HMR_3422"	""	"HMR_3422"	"RCR12667"	""	0	""	""	"FAOXC184C163m;HMR_3422;MAR03422"
 "MAR05364"	""	"FAOXC184C163x"	""	""	""	"FAOXC184C163x"	""	""	""	""	0	""	""	"FAOXC184C163x"
 "MAR05365"	""	"FAOXC184C164m"	""	""	""	"FAOXC184C164m"	""	""	""	""	0	""	""	"FAOXC184C164m"
@@ -9350,13 +9348,13 @@ rxns	rxnKEGGID	rxnBiGGID	rxnEHMNID	rxnHepatoNET1ID	rxnREACTOMEID	rxnRecon3DID	rx
 "MAR06278"	""	"FAOXC5OHc"	""	""	""	"FAOXC5OHc"	""	""	""	""	0	""	""	"FAOXC5OHc"
 "MAR06279"	""	"FAOXC61C4m"	""	""	""	"FAOXC61C4m"	""	""	""	""	0	""	""	"FAOXC61C4m"
 "MAR06280"	""	"FAOXC61C4x"	""	""	""	"FAOXC61C4x"	""	""	""	""	0	""	""	"FAOXC61C4x"
-"MAR06281"	""	"FAOXC61m"	""	""	""	"FAOXC61m"	""	""	""	""	0	""	""	"FAOXC61m"
+"MAR06281"	""	"FAOXC61m;HMR_3426"	""	""	""	"FAOXC61m;HMR_3426"	""	"HMR_3426"	"RCR12671"	""	0	""	""	"FAOXC61m;HMR_3426;MAR03426"
 "MAR06282"	""	"FAOXC61x"	""	""	""	"FAOXC61x"	""	""	""	""	0	""	""	"FAOXC61x"
 "MAR06283"	""	"FAOXC6C4m"	""	""	""	"FAOXC6C4m"	""	""	""	""	0	""	""	"FAOXC6C4m"
 "MAR06284"	""	"FAOXC6C4x"	""	""	""	"FAOXC6C4x"	""	""	""	""	0	""	""	"FAOXC6C4x"
 "MAR06285"	""	"FAOXC6DCC4DCx"	""	""	""	"FAOXC6DCC4DCx"	""	""	""	""	0	""	""	"FAOXC6DCC4DCx"
 "MAR06319"	""	"FAOXC7C5m"	""	""	""	"FAOXC7C5m"	""	""	""	""	0	""	""	"FAOXC7C5m"
-"MAR06320"	""	"FAOXC81C61m"	""	""	""	"FAOXC81C61m"	""	""	""	""	0	""	""	"FAOXC81C61m"
+"MAR06320"	""	"FAOXC81C61m;HMR_3426"	""	""	""	"FAOXC81C61m;HMR_3426"	""	"HMR_3426"	"RCR12671"	""	0	""	""	"FAOXC81C61m;HMR_3426;MAR03426"
 "MAR06322"	""	"FAOXC81C61x"	""	""	""	"FAOXC81C61x"	""	""	""	""	0	""	""	"FAOXC81C61x"
 "MAR06329"	""	"FAOXC8C6m"	""	""	""	"FAOXC8C6m"	""	""	""	""	0	""	""	"FAOXC8C6m"
 "MAR06344"	""	"FAOXC8C6x"	""	""	""	"FAOXC8C6x"	""	""	""	""	0	""	""	"FAOXC8C6x"