Changelog
All notable changes to this project will be documented in this file.
[1.0.0] - 2025-11-13
Release Notes
- Initial release of MethylPredict, a Nextflow pipeline for predicting DNA methylation from Oxford Nanopore sequencing data.
- Implements modular Nextflow DSL2 workflow with sample-wise output organization.
- Major features:
- No methylation calls required - Works with standard ONT basecalled data containing base quality values (Guppy, Dorado).
- Variant-aware methylation prediction - excludes CpG sites affected by variants.
- Supports execution with Docker, Singularity, Apptainer, and SLURM HPC environments.