Skip to content
View mohamedtalaat-gif's full-sized avatar
17 followers · 93 following

Block or report mohamedtalaat-gif

Block user

Prevent this user from interacting with your repositories and sending you notifications. Learn more about blocking users.

You must be logged in to block users.

Content in all repositories owned by your account will be closed.
Maximum 250 characters. Please don’t include any personal information such as legal names or email addresses. This note will only be visible to you.
Report abuse

Contact GitHub support about this user’s behavior. Learn more about reporting abuse.

Report abuse
mohamedtalaat-gif/README.md

Muhammad Talaat

Computational Pharmaceutics Engineer — BPharm, Ain Shams University.

I build open-source tools at the intersection of pharmaceutical science and computation: drug delivery system engineering, cheminformatics, QSAR/ADMET modeling, and the physics behind why a molecule does or doesn't reach where it needs to go.

CYPMode — Type I/II heme-coordination screen for TDC's binary CYP450 inhibition labels — structurally validated against real CYP3A4 cryo-EM data with Boltz-2.

PharmAMP — Pharmaceutical-developability metrics (aggregation propensity, solubility) for AI-designed antimicrobial peptides — seqme-compatible, validated against real wet-lab safety data.

CEREBRO-X — a computational pipeline for screening CNS drug-delivery formulations (PBPK, DLVO colloidal stability, docking, QSAR), built and audited in the open, including a public record of its own bugs found and fixed.

I'd rather ship something real and say what's still rough than ship something polished and hide what isn't.

Popular repositories Loading

  1. CYPMode CYPMode Public

    Reproducible predictors for time-dependent CYP3A4 and CYP2D6 inhibition and CYP3A4-ligand structures (OpenADMET CYP Inhibition Blind Challenge): nested cross-validation without selection bias, pre-…

    Python 6 1

  2. Stepan_Surfactant_Cheminformatics Stepan_Surfactant_Cheminformatics Public

    The surfactants and conditioning actives of the Stepan personal care seminar (Azelis, October 2026) as structures, physical chemistry and molecular dynamics: a cheminformatics dry lab with RDKit, O…

    Python 2

  3. mohamedtalaat-gif.github.io mohamedtalaat-gif.github.io Public

    Muhammad Talaat — personal site. Computational pharmaceutics, cheminformatics, drug delivery system engineering.

    HTML

  4. mohamedtalaat-gif mohamedtalaat-gif Public

    Profile README

  5. CEREBRO-X CEREBRO-X Public

    Open-source computational pipeline for CNS drug-delivery formulation screening — real PBPK, DLVO colloidal stability, AutoDock Vina docking, and ChEMBL-trained QSAR, with a public audit trail of it…

    Python

  6. PharmAMP PharmAMP Public

    Pharmaceutical-developability metrics (aggregation propensity, solubility) for AI-designed antimicrobial peptides — seqme-compatible, validated against real wet-lab safety data.

    Python